In 2017, John Preskill defined Noisy Intermediate Scale Quantum (NISQ) computers as an intermediate step on the road to large scale error corrected fault-tolerant quantum computers (FTQC). The NISQ regime corresponds to noisy qubit quantum computers with the potential to solve actual problems of some commercial value faster than conventional supercomputers, or consuming less energy. Over five years on, it is a good time to review the situation. While rapid progress is being made with quantum hardware and algorithms, and many recent experimental demonstrations, no one has yet successfully implemented a use case matching the original definition of the NISQ regime. This paper investigates the space, fidelity and time resources of various NISQ algorithms and highlights several contradictions between NISQ requirements and actual as well as future quantum hardware capabilities. It then covers various techniques which could help like qubit fidelities improvements, various breeds of quantum error mitigation methods, analog/digital hybridization, using specific qubit types like multimode photons as well as quantum annealers and analog quantum computers (aka quantum simulators or programmable Hamiltonian simulators) which seem closer to delivering useful applications although they have their own mid to longer-term scalability challenges. Given all the constraints of these various solutions, it seems possible to expect some practical use cases for NISQ systems, but with a very narrow window before various scaling issues show up. Turning to the future, a scenario can be envisioned where NISQ will not necessarily be an intermediate step on the road to FTQC. Instead, the two may develop along different paths, due to their different requirements. This leaves open a key question on the trade-offs that may be necessary to make between qubit scale and qubit fidelities in future quantum computers designs.
In 2017, John Preskill defined Noisy Intermediate Scale Quantum (NISQ) computers as an intermediate step on the road to large scale error corrected fault-tolerant quantum computers (FTQC). The NISQ regime corresponds to noisy qubit quantum computers with the potential to solve actual problems of some commercial value faster than conventional supercomputers, or consuming less energy. Over five years on, it is a good time to review the situation. While rapid progress is being made with quantum hardware and algorithms, and many recent experimental demonstrations, no one has yet successfully implemented a use case matching the original definition of the NISQ regime. This paper investigates the space, fidelity and time resources of various NISQ algorithms and highlights several contradictions between NISQ requirements and actual as well as future quantum hardware capabilities. It then covers various techniques which could help like qubit fidelities improvements, various breeds of quantum error mitigation methods, analog/digital hybridization, using specific qubit types like multimode photons as well as quantum annealers and analog quantum computers (aka quantum simulators or programmable Hamiltonian simulators) which seem closer to delivering useful applications although they have their own mid to longer-term scalability challenges. Given all the constraints of these various solutions, it seems possible to expect some practical use cases for NISQ systems, but with a very narrow window before various scaling issues show up. Turning to the future, a scenario can be envisioned where NISQ will not necessarily be an intermediate step on the road to FTQC. Instead, the two may develop along different paths, due to their different requirements. This leaves open a key question on the trade-offs that may be necessary to make between qubit scale and qubit fidelities in future quantum computers designs.
Noisy Intermediate-Scale Quantum Computing (NISQ) has dominated headlines in recent years, with the longer-term vision of Fault-Tolerant Quantum Computation (FTQC) offering significant potential albeit at currently intractable resource costs and quantum error correction (QEC) overheads. For problems of interest, FTQC will require millions of physical qubits with long coherence times, high-fidelity gates, and compact sizes to surpass classical systems. Just as heterogeneous specialization has offered scaling benefits in classical computing, it is likewise gaining interest in FTQC. However, systematic use of heterogeneity in either hardware or software elements of FTQC systems remains a serious challenge due to the vast design space and variable physical constraints.
Abstract There has been a good deal of work on algorithms to simulate quantum many-body systems with fault-tolerant quantum computers- those with full error correction. Fault-tolerant quantum computers of scale requisite to achieve computational advantage for these problems are likely over a decade away. Moreover, devices that we can build in the near term, called Noisy Intermediate Scale Quantum computers (NISQ), have too much noise to implement the long circuits required by these algorithms. We review heuristic, short-depth quantum algorithms more suited to NISQ computers; specifically, their scaling properties when applied to electronic and nuclear structure calculations, including Hamiltonian complexity with particle number, ansatz state preparation, convergence, and noise. We will present examples of actual quantum structure calculations with NISQ computers, as well as a newly-developed error mitigation technique that significantly improves accuracy. We end with an outlook for “advantage” – when NISQ systems might excel conventional HPC approaches for comparable problems.
Quantum computing is entering a transitional regime between noisy intermediate-scale quantum (NISQ) processing and early fault-tolerant quantum computation (FTQC), in which increasingly capable hardware is beginning to support repeated syndrome measurements, partial error correction, and logical-qubit operations, while residual physical and logical errors remain non-negligible. In this regime, error suppression, error mitigation, and quantum error correction are increasingly better viewed as complementary layers of a unified error-reduction strategy rather than as separate approaches, with each acting at a different stage of the quantum computation to improve simulation reliability. Thus, in this review, we provide a practical and forward-looking overview of the principal hardware error sources and the corresponding error suppression and mitigation methods for reducing their impact across the current NISQ-FTQC transition. We discuss hardware-aware circuit design, coherent-error suppression, readout mitigation, noise extrapolation, classical inference, and software-supported workflows, with particular emphasis on their implementation on actual quantum processors. We further examine how error mitigation techniques can be adapted to encoded and logical-qubit settings so that they can operate alongside quantum error correction to suppress residual logical errors and improve the accuracy of computation in the early fault-tolerant regime.
A universal fault-tolerant quantum computer that can solve efficiently problems such as integer factorization and unstructured database search requires millions of qubits with low error rates and long coherence times. While the experimental advancement towards realizing such devices will potentially take decades of research, noisy intermediate-scale quantum (NISQ) computers already exist. These computers are composed of hundreds of noisy qubits, i.e. qubits that are not error-corrected, and therefore perform imperfect operations in a limited coherence time. In the search for quantum advantage with these devices, algorithms have been proposed for applications in various disciplines spanning physics, machine learning, quantum chemistry and combinatorial optimization. The goal of such algorithms is to leverage the limited available resources to perform classically challenging tasks. In this review, we provide a thorough summary of NISQ computational paradigms and algorithms. We discuss the key structure of these algorithms, their limitations, and advantages. We additionally provide a comprehensive overview of various benchmarking and software tools useful for programming and testing NISQ devices.
Noisy intermediate-scale quantum (NISQ) computers are coming online. The lack of error-correction in these devices prevents them from realizing the full potential of fault-tolerant quantum computation, a technology that is known to have significant practical applications, but which is years, if not decades, away. A major open question is whether NISQ devices will have practical applications. In this thesis, we explore and implement proposals for using NISQ devices to achieve practical applications. In particular, we develop and execute variational quantum algorithms for solving problems in combinatorial optimization and quantum chemistry. We also execute a prototype of a protocol for generating certified random numbers. We perform our experiments on a superconducting qubit processor developed at Google. While we do not perform any quantum computations that are beyond the capabilities of classical computers, we address many implementation challenges that must be overcome to succeed in such an endeavor, including optimization, efficient compilation, and error mitigation. In addressing these challenges, we push the limits of what can currently be done with NISQ technology, going beyond previous quantum computing demonstrations in terms of the scale of our experiments and the types of problems we tackle. While our experiments demonstrate progress in the utilization of quantum computers, the limits that we reached underscore the fundamental challenges in scaling up towards the classically intractable regime. Nevertheless, our results are a promising indication that NISQ devices may indeed deliver practical applications.
Quantum computing has emerged as a transformative paradigm capable of addressing computational challenges beyond the reach of classical systems.In the current era of Noisy Intermediate-Scale Quantum (NISQ) devices, practical quantum hardware is characterized by limited qubit counts, short coherence times, gate errors, and the absence of full error correction.Despite these constraints, significant progress has been made in developing quantum machine learning (QML) techniques tailored to operate on near-term quantum processors.This paper presents a comprehensive review of Quantum Machine Learning in the context of NISQ computing.We first outline the fundamental principles of quantum computing, including qubits, superposition, entanglement, and quantum parallelism, followed by a detailed discussion of the NISQ computing model and its hardware limitations.The review then examines hybrid quantum-classical learning frameworks, variational quantum algorithms, quantum data encoding strategies, and noise mitigation techniques that enable practical implementation on existing platforms.Emerging applications across healthcare, finance, cybersecurity, climate modeling, and materials science are also surveyed to highlight the real-world potential of QML.Furthermore, key challenges such as scalability, trainability issues, and algorithmic robustness are analyzed, along with current research efforts aimed at overcoming these barriers.The paper concludes by identifying promising future directions for advancing QML toward quantum advantage.This review aims to provide researchers and practitioners with a structured understanding of the capabilities, limitations, and opportunities of quantum machine learning in the NISQ era .