Kishor Bharti, Alba Cervera-Lierta, Thi Ha Kyaw, Tobias Haug, Sumner Alperin-Lea, Abhinav Anand, Matthias Degroote, Hermanni Heimonen, Jakob S. Kottmann, Tim Menke, Wai‐Keong Mok, Sukin Sim, L. C. Kwek, Alán Aspuru‐Guzik
A universal fault-tolerant quantum computer that can solve efficiently problems such as integer factorization and unstructured database search requires millions of qubits with low error rates and long coherence times. While the experimental advancement towards realizing such devices will potentially take decades of research, noisy intermediate-scale quantum (NISQ) computers already exist. These computers are composed of hundreds of noisy qubits, i.e. qubits that are not error-corrected, and therefore perform imperfect operations in a limited coherence time. In the search for quantum advantage with these devices, algorithms have been proposed for applications in various disciplines spanning physics, machine learning, quantum chemistry and combinatorial optimization. The goal of such algorithms is to leverage the limited available resources to perform classically challenging tasks. In this review, we provide a thorough summary of NISQ computational paradigms and algorithms. We discuss the key structure of these algorithms, their limitations, and advantages. We additionally provide a comprehensive overview of various benchmarking and software tools useful for programming and testing NISQ devices.
A universal fault-tolerant quantum computer that can solve efficiently problems such as integer factorization and unstructured database search requires millions of qubits with low error rates and long coherence times. While the experimental advancement towards realizing such devices will potentially take decades of research, noisy intermediate-scale quantum (NISQ) computers already exist. These computers are composed of hundreds of noisy qubits, i.e. qubits that are not error-corrected, and therefore perform imperfect operations in a limited coherence time. In the search for quantum advantage with these devices, algorithms have been proposed for applications in various disciplines spanning physics, machine learning, quantum chemistry and combinatorial optimization. The goal of such algorithms is to leverage the limited available resources to perform classically challenging tasks. In this review, we provide a thorough summary of NISQ computational paradigms and algorithms. We discuss the key structure of these algorithms, their limitations, and advantages. We additionally provide a comprehensive overview of various benchmarking and software tools useful for programming and testing NISQ devices.
<!--HTML-->A universal fault-tolerant quantum computer that can solve efficiently problems such as integer factorization and unstructured database search requires millions of qubits with low error rates and long coherence times. While the experimental advancement towards realizing such devices will potentially take decades of research, noisy intermediate-scale quantum (NISQ) computers already exist. These computers are composed of hundreds of noisy qubits, i.e. qubits that are not error-corrected, and therefore perform imperfect operations in a limited coherence time. In the search for quantum advantage with these devices, algorithms have been proposed for applications in various disciplines spanning physics, machine learning, quantum chemistry and combinatorial optimization. The goal of such algorithms is to leverage the limited available resources to perform classically challenging tasks. In this talk, I provide an overview of NISQ algorithms, their limitations and potential advantages.
Quantum computing has the potential to solve complex problems that are outside the scope of classical systems, making it a standard shifter. Current devices, which are considered as Noisy Intermediate-Scale Quantum (NISQ) systems, are insufficient in their practical utility due to hardware limitations, error rates, and qubit counts. The dynamic growths wanted to exceed the NISQ era and grow scalable quantum algorithms and architectures that can achieve useful quantum benefit in real-world applications are reviewed in this research. This research gives a comprehensive examination of the complications in scaling quantum systems, adjacent resource efficacy, qubit connectivity, and error correction. In addition to connecting architectural innovations like modular quantum computing, error-resilient circuit design, and distributed quantum systems, the paper provides new hybrid quantum-classical algorithms planned to exploit performance in noisy environments. Results from benchmarking in arenas like machine learning, optimization, and quantum chemistry show how these methods can provide short-term quantum benefit. Lastly, this paper proposes a research roadmap for quantum computing that highlights the requirement of co-designing algorithms, software, and hardware. The goal of this effort is to straighten the progress of quantum systems that can resolve problems in the real world at scale by addressing the inadequacies of NISQ devices and emphasizing scalable solutions.
Quantum computing has emerged as a transformative paradigm capable of addressing computational challenges beyond the reach of classical systems.In the current era of Noisy Intermediate-Scale Quantum (NISQ) devices, practical quantum hardware is characterized by limited qubit counts, short coherence times, gate errors, and the absence of full error correction.Despite these constraints, significant progress has been made in developing quantum machine learning (QML) techniques tailored to operate on near-term quantum processors.This paper presents a comprehensive review of Quantum Machine Learning in the context of NISQ computing.We first outline the fundamental principles of quantum computing, including qubits, superposition, entanglement, and quantum parallelism, followed by a detailed discussion of the NISQ computing model and its hardware limitations.The review then examines hybrid quantum-classical learning frameworks, variational quantum algorithms, quantum data encoding strategies, and noise mitigation techniques that enable practical implementation on existing platforms.Emerging applications across healthcare, finance, cybersecurity, climate modeling, and materials science are also surveyed to highlight the real-world potential of QML.Furthermore, key challenges such as scalability, trainability issues, and algorithmic robustness are analyzed, along with current research efforts aimed at overcoming these barriers.The paper concludes by identifying promising future directions for advancing QML toward quantum advantage.This review aims to provide researchers and practitioners with a structured understanding of the capabilities, limitations, and opportunities of quantum machine learning in the NISQ era .
Quantum computing has transitioned from a theoretical curiosity to an emerging technological paradigm with demonstrable computational advantages in specific problem domains. This paper presents a comprehensive review of current advances in quantum computing hardware, software, and near-term applications within the Noisy Intermediate-Scale Quantum (NISQ) era. We examine the architectural evolution of leading quantum platforms, including superconducting, trapped-ion, and photonic systems, analyzing their qubit counts, gate fidelities, and coherence times. The paper evaluates key quantum algorithms Shor's factoring algorithm [1], Grover's search algorithm [2], the Variational Quantum Eigensolver (VQE) [3], and the Quantum Approximate Optimization Algorithm (QAOA) [4] in the context of their practical applicability to real-world problems. We further discuss the milestone of quantum computational advantage demonstrated by Google's Sycamore processor [5] and IBM's ambitious hardware roadmap toward fault-tolerant quantum computing [6]. Our analysis reveals that while universal fault-tolerant quantum computing remains a long-term objective, NISQ-era devices are already yielding valuable results in quantum chemistry simulation, combinatorial optimization, and quantum machine learning. We conclude by identifying the critical challenges—error correction, scalability, and algorithm design that must be addressed to realize the full potential of quantum computing.
The Noisy Intermediate-Scale Quantum (NISQ) era, defined by qubit counts in the hundreds and gate error rates that preclude long coherence times, imposes severe constraints on purely quantum computation. The central problem is that achieving practical quantum advantage for real-world tasks must overcome these hardware limitations, yet fault-tolerant quantum computers with full error correction remain years away. To address this, we present a systematic survey of hybrid classical-quantum computing models, in which classical high-performance resources orchestrate the workflow, perform iterative optimization, and apply error mitigation to noisy quantum processing units. Our review encompasses variational quantum algorithms, such as the variational quantum eigensolver and quantum approximate optimization algorithm; classical optimizers tailored for noisy quantum landscapes; error mitigation techniques including zero-noise extrapolation and probabilistic error cancellation; and circuit knitting that partitions large circuits across small QPUs. We find that these hybrid architectures have already demonstrated domain-specific utility in quantum chemistry for molecular ground-state estimation, in logistics and finance for combinatorial optimization, and in machine learning for generative and recommendation models. Notably, they often surpass purely classical or purely quantum approaches on carefully chosen benchmarks. The evidence indicates that hybrid classical-quantum systems are not a temporary stopgap but a durable paradigm. Their role will persist into the early fault-tolerant era, where small, logical qubits will similarly require classical coordination. Consequently, the field urgently demands the establishment of standardized hybrid performance benchmarks, the maturation of robust quantum-classical middleware capable of efficient transpiration and execution management, and holistic co-design frameworks that seamlessly integrate hardware constraints, software stack layers, and application-specific requirements from the outset.
Variational Quantum Algorithms are a major method of harnessing Noisy Intermediate-Scale Quantum devices to solve classically intractable problems in physics, chemistry, optimization, and machine learning. The current review offers a critical overview of VQAs, with special emphasis on their theoretical backgrounds, algorithmic structures, and application performance within realistic models of noise. Several key variants, such as the Variational Quantum Eigensolver, Quantum Approximate Optimization Algorithm, and Quantum Neural Networks, are compared in terms of noise robustness, ansatz archi- tecture, and hybrid quantum-classical methods of optimization. Benchmarks in fields such as quantum chemistry, finance modeling, and particles and nuclei physics reveal the poten- tial of VQAs in achieving practical quantum advantage. Fundamentally limiting factors 1such as barren plateaus, optimization overhead, and hardware constraints are considered in addition to mitigation strategies, including adaptive construction of ansatz, informed training in the presence of noise, and quantum error correction using QVECTOR. The paper is concluded with an overview of the scalability and future of VQAs in the direction of transitioning toward fault-tolerant quantum computing.