<!--HTML-->A universal fault-tolerant quantum computer that can solve efficiently problems such as integer factorization and unstructured database search requires millions of qubits with low error rates and long coherence times. While the experimental advancement towards realizing such devices will potentially take decades of research, noisy intermediate-scale quantum (NISQ) computers already exist. These computers are composed of hundreds of noisy qubits, i.e. qubits that are not error-corrected, and therefore perform imperfect operations in a limited coherence time. In the search for quantum advantage with these devices, algorithms have been proposed for applications in various disciplines spanning physics, machine learning, quantum chemistry and combinatorial optimization. The goal of such algorithms is to leverage the limited available resources to perform classically challenging tasks. In this talk, I provide an overview of NISQ algorithms, their limitations and potential advantages.
<!--HTML-->A universal fault-tolerant quantum computer that can solve efficiently problems such as integer factorization and unstructured database search requires millions of qubits with low error rates and long coherence times. While the experimental advancement towards realizing such devices will potentially take decades of research, noisy intermediate-scale quantum (NISQ) computers already exist. These computers are composed of hundreds of noisy qubits, i.e. qubits that are not error-corrected, and therefore perform imperfect operations in a limited coherence time. In the search for quantum advantage with these devices, algorithms have been proposed for applications in various disciplines spanning physics, machine learning, quantum chemistry and combinatorial optimization. The goal of such algorithms is to leverage the limited available resources to perform classically challenging tasks. In this talk, I provide an overview of NISQ algorithms, their limitations and potential advantages.
A universal fault-tolerant quantum computer that can solve efficiently problems such as integer factorization and unstructured database search requires millions of qubits with low error rates and long coherence times. While the experimental advancement towards realizing such devices will potentially take decades of research, noisy intermediate-scale quantum (NISQ) computers already exist. These computers are composed of hundreds of noisy qubits, i.e. qubits that are not error-corrected, and therefore perform imperfect operations in a limited coherence time. In the search for quantum advantage with these devices, algorithms have been proposed for applications in various disciplines spanning physics, machine learning, quantum chemistry and combinatorial optimization. The goal of such algorithms is to leverage the limited available resources to perform classically challenging tasks. In this review, we provide a thorough summary of NISQ computational paradigms and algorithms. We discuss the key structure of these algorithms, their limitations, and advantages. We additionally provide a comprehensive overview of various benchmarking and software tools useful for programming and testing NISQ devices.
Quantum computing has transitioned from a theoretical curiosity to an emerging technological paradigm with demonstrable computational advantages in specific problem domains. This paper presents a comprehensive review of current advances in quantum computing hardware, software, and near-term applications within the Noisy Intermediate-Scale Quantum (NISQ) era. We examine the architectural evolution of leading quantum platforms, including superconducting, trapped-ion, and photonic systems, analyzing their qubit counts, gate fidelities, and coherence times. The paper evaluates key quantum algorithms Shor's factoring algorithm [1], Grover's search algorithm [2], the Variational Quantum Eigensolver (VQE) [3], and the Quantum Approximate Optimization Algorithm (QAOA) [4] in the context of their practical applicability to real-world problems. We further discuss the milestone of quantum computational advantage demonstrated by Google's Sycamore processor [5] and IBM's ambitious hardware roadmap toward fault-tolerant quantum computing [6]. Our analysis reveals that while universal fault-tolerant quantum computing remains a long-term objective, NISQ-era devices are already yielding valuable results in quantum chemistry simulation, combinatorial optimization, and quantum machine learning. We conclude by identifying the critical challenges—error correction, scalability, and algorithm design that must be addressed to realize the full potential of quantum computing.
Quantum computing has the potential to solve complex problems that are outside the scope of classical systems, making it a standard shifter. Current devices, which are considered as Noisy Intermediate-Scale Quantum (NISQ) systems, are insufficient in their practical utility due to hardware limitations, error rates, and qubit counts. The dynamic growths wanted to exceed the NISQ era and grow scalable quantum algorithms and architectures that can achieve useful quantum benefit in real-world applications are reviewed in this research. This research gives a comprehensive examination of the complications in scaling quantum systems, adjacent resource efficacy, qubit connectivity, and error correction. In addition to connecting architectural innovations like modular quantum computing, error-resilient circuit design, and distributed quantum systems, the paper provides new hybrid quantum-classical algorithms planned to exploit performance in noisy environments. Results from benchmarking in arenas like machine learning, optimization, and quantum chemistry show how these methods can provide short-term quantum benefit. Lastly, this paper proposes a research roadmap for quantum computing that highlights the requirement of co-designing algorithms, software, and hardware. The goal of this effort is to straighten the progress of quantum systems that can resolve problems in the real world at scale by addressing the inadequacies of NISQ devices and emphasizing scalable solutions.
Noisy intermediate-scale quantum (NISQ) computers are coming online. The lack of error-correction in these devices prevents them from realizing the full potential of fault-tolerant quantum computation, a technology that is known to have significant practical applications, but which is years, if not decades, away. A major open question is whether NISQ devices will have practical applications. In this thesis, we explore and implement proposals for using NISQ devices to achieve practical applications. In particular, we develop and execute variational quantum algorithms for solving problems in combinatorial optimization and quantum chemistry. We also execute a prototype of a protocol for generating certified random numbers. We perform our experiments on a superconducting qubit processor developed at Google. While we do not perform any quantum computations that are beyond the capabilities of classical computers, we address many implementation challenges that must be overcome to succeed in such an endeavor, including optimization, efficient compilation, and error mitigation. In addressing these challenges, we push the limits of what can currently be done with NISQ technology, going beyond previous quantum computing demonstrations in terms of the scale of our experiments and the types of problems we tackle. While our experiments demonstrate progress in the utilization of quantum computers, the limits that we reached underscore the fundamental challenges in scaling up towards the classically intractable regime. Nevertheless, our results are a promising indication that NISQ devices may indeed deliver practical applications.
Quantum computing is expected to offer exponential or polynomial speedups over classical computing for many socially important problems, including integer factorization, combinatorial optimization, and quantum chemistry.This promise has fueled strong expectations for quantum computers as next-generation computing infrastructure.Most algorithms with provable quantum advantage require large-scale quantum error correction, making fault-tolerant quantum computers (FTQC) essential.However, currently available devices are noisy intermediate-scale quantum (NISQ) devices, and further breakthroughs, such as advances in large-scale integration, are required to realize practical implementations of quantum error correction.
The Noisy Intermediate-Scale Quantum (NISQ) era, defined by qubit counts in the hundreds and gate error rates that preclude long coherence times, imposes severe constraints on purely quantum computation. The central problem is that achieving practical quantum advantage for real-world tasks must overcome these hardware limitations, yet fault-tolerant quantum computers with full error correction remain years away. To address this, we present a systematic survey of hybrid classical-quantum computing models, in which classical high-performance resources orchestrate the workflow, perform iterative optimization, and apply error mitigation to noisy quantum processing units. Our review encompasses variational quantum algorithms, such as the variational quantum eigensolver and quantum approximate optimization algorithm; classical optimizers tailored for noisy quantum landscapes; error mitigation techniques including zero-noise extrapolation and probabilistic error cancellation; and circuit knitting that partitions large circuits across small QPUs. We find that these hybrid architectures have already demonstrated domain-specific utility in quantum chemistry for molecular ground-state estimation, in logistics and finance for combinatorial optimization, and in machine learning for generative and recommendation models. Notably, they often surpass purely classical or purely quantum approaches on carefully chosen benchmarks. The evidence indicates that hybrid classical-quantum systems are not a temporary stopgap but a durable paradigm. Their role will persist into the early fault-tolerant era, where small, logical qubits will similarly require classical coordination. Consequently, the field urgently demands the establishment of standardized hybrid performance benchmarks, the maturation of robust quantum-classical middleware capable of efficient transpiration and execution management, and holistic co-design frameworks that seamlessly integrate hardware constraints, software stack layers, and application-specific requirements from the outset.