Abstract The pursuit of practical quantum utility on near-term quantum processors is critically challenged by their inherent noise. Quantum error mitigation (QEM) techniques are leading solutions to improve computation fidelity with relatively low qubit-overhead, while full-scale quantum error correction remains a distant goal. However, QEM techniques incur substantial measurement overheads, especially when applied to families of quantum circuits parameterized by classical inputs. Focusing on zero-noise extrapolation (ZNE), a widely adopted QEM technique, here we devise the surrogate-enabled ZNE (S-ZNE), which leverages classical learning surrogates to perform ZNE entirely on the classical side. Unlike conventional ZNE, whose measurement cost scales linearly with the number of circuits, S-ZNE requires only constant measurement overhead for an entire family of quantum circuits, offering superior scalability. Theoretical analysis indicates that S-ZNE achieves accuracy comparable to conventional ZNE in many practical scenarios, and numerical experiments on up to 100-qubit ground-state energy and quantum metrology tasks confirm its effectiveness. Our approach provides a template that can be effectively extended to other quantum error mitigation protocols, opening a promising path toward scalable error mitigation.
Abstract The pursuit of practical quantum utility on near-term quantum processors is critically challenged by their inherent noise. Quantum error mitigation (QEM) techniques are leading solutions to improve computation fidelity with relatively low qubit-overhead, while full-scale quantum error correction remains a distant goal. However, QEM techniques incur substantial measurement overheads, especially when applied to families of quantum circuits parameterized by classical inputs. Focusing on zero-noise extrapolation (ZNE), a widely adopted QEM technique, here we devise the surrogate-enabled ZNE (S-ZNE), which leverages classical learning surrogates to perform ZNE entirely on the classical side. Unlike conventional ZNE, whose measurement cost scales linearly with the number of circuits, S-ZNE requires only constant measurement overhead for an entire family of quantum circuits, offering superior scalability. Theoretical analysis indicates that S-ZNE achieves accuracy comparable to conventional ZNE in many practical scenarios, and numerical experiments on up to 100-qubit ground-state energy and quantum metrology tasks confirm its effectiveness. Our approach provides a template that can be effectively extended to other quantum error mitigation protocols, opening a promising path toward scalable error mitigation.
The pursuit of practical quantum utility on near-term quantum processors is critically challenged by their inherent noise. Quantum error mitigation (QEM) techniques are leading solutions to improve computation fidelity with relatively low qubit-overhead, while full-scale quantum error correction remains a distant goal. However, QEM techniques incur substantial measurement overheads, especially when applied to families of quantum circuits parameterized by classical inputs. Focusing on zero-noise extrapolation (ZNE), a widely adopted QEM technique, here we devise the surrogate-enabled ZNE (S-ZNE), which leverages classical learning surrogates to perform ZNE entirely on the classical side. Unlike conventional ZNE, whose measurement cost scales linearly with the number of circuits, S-ZNE requires only constant measurement overhead for an entire family of quantum circuits, offering superior scalability. Theoretical analysis indicates that S-ZNE achieves accuracy comparable to conventional ZNE in many practical scenarios, and numerical experiments on up to 100-qubit ground-state energy and quantum metrology tasks confirm its effectiveness. Our approach provides a template that can be effectively extended to other quantum error mitigation protocols, opening a promising path toward scalable error mitigation.
We present a simple, malleable and low-overhead approach for improving generic biased quantum error mitigation (QEM) methods, achieving up to 15% fidelity improvements over standard QEM on 100-qubit circuits with up to 2000 entangling gates. We do so by constructing verifiable benchmark circuits which mirror the application circuit's native-gate structure and thus noise profile. These circuits can be used to benchmark and mitigate the bias of the underlying error mitigation method, requiring only the application circuit and hardware native gate set. We present two methods for generating benchmark circuits; one is agnostic to the target hardware at the expense of a small overhead of single-qubit gates, while the other is specific to the IBM superconducting hardware and has no gate overhead. As a corollary, we introduce benchmarked-noise zero-noise extrapolation (bnZNE) as a simple adaptation of zero-noise extrapolation (ZNE), one of the most popular error mitigation methods. We consider as an example the bias-mitigated ZNE and bnZNE of Trotterized Hamiltonian simulations, observing that our approaches outperform standard ZNE using both small-scale classical simulations and 100-qubit utility-scale experiments on the IBM superconducting hardware. We consider the measurement of both single-site observables as well as two-site correlations along a one-dimensional qubit chain. We also provide a software package for implementing the error mitigation techniques used in this research.
Noise in quantum hardware is the primary obstacle to realizing the transformative potential of quantum computing. Quantum error mitigation (QEM) offers a promising pathway to enhance computational accuracy on near-term devices, yet existing methods face a difficult trade-off between performance, resource overhead, and theoretical guarantees. In this work, we introduce neighbor-informed learning (NIL), a versatile and scalable QEM framework that unifies and strengthens existing methods such as zero-noise extrapolation (ZNE) and probabilistic error cancellation (PEC), while offering improved flexibility, accuracy, efficiency, and robustness.
NIL learns to predict the ideal output of a target quantum circuit from the noisy outputs of its structurally related ``neighbor'' circuits. A key innovation is our 2-design training method, which generates training data for our machine learning model. In contrast to conventional learning-based QEM protocols that create training circuits by replacing non-Clifford gates with uniformly random Clifford gates, our approach achieves higher accuracy and efficiency, as demonstrated by both theoretical analysis and numerical simulation. Furthermore, we prove that the required size of the training set scales only \emph{logarithmically} with the total number of neighbor circuits, enabling NIL to be applied to problems involving large-scale quantum circuits. Our work establishes a theoretically grounded and practically efficient framework for QEM, paving a viable path toward achieving quantum advantage on noisy hardware.
Quantum error mitigation (QEM) infers noiseless expectation values from noisy variants of a target quantum circuit. Unlike quantum error correction, QEM requires no additional hardware resources and is therefore routinely employed in experiments on contemporary quantum processors. QEM strategies based on agnostic noise amplification (ANA) are intrinsically resilient to temporal noise drift during the execution of the experiment, but their sampling cost (runtime overhead) remains a major practical bottleneck. In this work, we introduce the virtual noise scaling framework and combine it with layered mitigation to further enhance performance. While virtual noise scaling consistently reduces sampling overhead, we identify a specific noise threshold for the layered mitigation approach. When the noise level is above this threshold, layered mitigation decreases the sampling overhead; conversely, when below it, the overhead increases. Notably, this threshold is circuit-independent and depends solely on the number of layers. For strong noise, the combination of virtual noise scaling and layered mitigation yields several orders of magnitude reduction in sampling overhead compared with conventional zero-noise extrapolation post-processing. As a result, mitigation tasks that once seemed unrealistic are now challenging but achievable. The proposed approach is compatible with dynamic circuits and can be seamlessly integrated with error detection and quantum error correction schemes. In addition, it is also applicable to ANA-based mitigation of mid-circuit measurements and preparation errors. Our findings extend to any constant-step amplification factors and therefore also apply to probabilistic error amplification (PEA) QEM. We validate our post-processing approach by applying it to previously reported experimental data, where we observe a substantial improvement in mitigation efficiency and accuracy.
Quantum error mitigation (QEM) bridges the gap between today's noisy NISQ hardware and fault-tolerant quantum computing by reducing the effect of hardware errors on expectation value estimates without the qubit overhead of full quantum error correction. This paper proposes the Quantum Error Mitigation Design (QEMD) framework, a systematic evaluation of six QEM techniques across four circuit families on IBM Quantum Eagle and IonQ Forte: Zero-Noise Extrapolation (ZNE), Probabilistic Error Cancellation (PEC), Clifford Data Regression (CDR), Symmetry Verification (SV), Dynamical Decoupling (DD), and a novel Adaptive Ensemble Mitigation (AEM) combining ZNE and CDR with context-aware technique selection. QEMD finds: ZNE 3-point Richardson provides the best cost-performance trade-off for QAOA and VQE circuits (4.8x overhead, 28.4pp error reduction); PEC provides the highest accuracy but at 48x shot overhead -- practical only for n <= 12; DD reduces coherence-limited errors by 18.4% on IonQ Forte at zero shot overhead; AEM outperforms all individual techniques by 6.4pp at 8.4x overhead. QEMD provides a decision guide mapping circuit type, qubit count, and shot budget to optimal QEM technique selection.
Abstract Quantum error mitigation is a key enabling technique for extracting reliable computational results from noisy intermediate-scale quantum devices. Among existing approaches, zero-noise extrapolation (ZNE) is widely employed, but its effectiveness deteriorates in high-noise regimes or deep circuits, where measurement outcomes converge to the random-guessing limit. To address this issue, we propose a lightweight, extrapolation-based error mitigation framework that leverages the intrinsic repetitive structure of quantum algorithms. We classify these algorithms into homogeneous and heterogeneous types and efficiently estimate block fidelities using shallow identity sequences of the core operational block, thereby avoiding global circuit folding. Experiments on IBM’s advanced superconducting platform and its corresponding simulator demonstrate that the proposed framework remains effective even in high-noise regimes where folding-based ZNE(f-ZNE) fails due to noise saturation. For a four-qubit Grover search, our approach restores the success probability to near its theoretical value, whereas f-ZNE yields negligible improvement. We further validate the proposed method on a 17-qubit quantum approximate optimization algorithm with layer-dependent parameters, demonstrating robustness beyond fixed-structure circuits. These results indicate that leveraging algorithmic structure provides a practical pathway to extending the performance of extrapolation-based error mitigation on current quantum processors.