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Quantum Reports

A Hybrid Quantum-Classical Framework for Saliency-Aware Medical Image Encoding

Vrushali Nikam, Trupti S. Atre, Lavanya Santhosh, Asha K N, Praveena M.V

Published May 7, 2026• 0 citations
Publisher

Abstract

Quantum image processing provides significant storage benefits over classical methods. However, current quantum image representation techniques exhibit limitations regarding encoding efficiency, circuit complexity, and adaptability to image content. This paper proposes Saliency-Aware Hybrid Quantum Image Representation (SAHQR), utilizing saliency detection for content-adaptive representation. It selectively focuses on salient regions, allocating quantum resources proportionally to visual importance, whereas existing techniques represent all regions uniformly.The proposed approach is evaluated against ten state-of-the-art quantum image representation techniques using ten criteria: number of qubits, circuit depth, gate complexity, encoding time, scalability, information loss, compression ratio, memory overhead, and implementation complexity Experimental results on 6097 medical images from the MINC database demonstrate that this work should be interpreted as a proof of concept for saliency-aware quantum encoding, rather than as a universally optimal representation.The evaluation is extended to 2000 Synthetic Aperture Radar (SAR) tiles and 2298 Brain Tumor MRI scans to validate cross-domain generalization. Statistical significance tests (p < 0.001) confirm SAHQR yields statistically significant improvements over existing techniques across all three domains.

DOI
10.3390/quantum8020046

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Physica Scripta•Nov 18, 2025•1 citation
Quantum image processing provides significant storage benefits over classical methods. However, current quantum image representation techniques exhibit limitations regarding encoding efficiency, circuit complexity, and adaptability to image content. This paper proposes Saliency-Aware Hybrid Quantum Image Representation (SAHQR), utilizing saliency detection for content-adaptive representation. It selectively focuses on salient regions, allocating quantum resources proportionally to visual importance, whereas existing techniques represent all regions uniformly.The proposed approach is evaluated against ten state-of-the-art quantum image representation techniques using ten criteria: number of qubits, circuit depth, gate complexity, encoding time, scalability, information loss, compression ratio, memory overhead, and implementation complexity Experimental results on 6097 medical images from the MINC database demonstrate that this work should be interpreted as a proof of concept for saliency-aware quantum encoding, rather than as a universally optimal representation.The evaluation is extended to 2000 Synthetic Aperture Radar (SAR) tiles and 2298 Brain Tumor MRI scans to validate cross-domain generalization. Statistical significance tests (p < 0.001) confirm SAHQR yields statistically significant improvements over existing techniques across all three domains.
Abstract Quantum image representation constitutes a foundational component of quantum image processing; however, its practical deployment on Noisy Intermediate-Scale Quantum (NISQ) hardware is fundamentally constrained by the cost of quantum state preparation. Existing representations such as the Flexible Representation of Quantum Images (FRQI) and the Novel Enhanced Quantum Representation (NEQR) rely on uniform, full-resolution encoding strategies that incur rapidly increasing gate counts and circuit depths, leading to severe decoherence and error accumulation on near-term devices. These limitations are particularly pronounced for heterogeneous and information-sparse modalities such as medical Magnetic Resonance Imaging (MRI) and Synthetic Aperture Radar (SAR), where uniform pixel-wise encoding introduces substantial redundant state preparation. To address these constraints, we propose Adaptive Hybrid Quantum Image Representation (AHQIR), a saliency-driven selective quantum state-preparation framework designed for efficient encoding of medical and SAR imagery under NISQ limitations. AHQIR departs from global encoding by employing a classical adaptive preprocessing stage to identify diagnostically significant regions in MRI and dominant backscatter structures in SAR images using a statistical thresholding criterion, thereby restricting quantum encoding to a salient pixel subset S. The quantum realization of AHQIR integrates Perception-Aided Encoding (PE) and Coherent-Size Encoding (CE) mechanisms, which condition state preparation on salient pixel coordinates and eliminate the requirement for power-of-two image padding. As a result, circuit depth and multi-qubit gate count scale with the number of salient pixels rather than total image size, enabling physically realizable circuits within current coherence limits. This selective and intentionally lossy design sacrifices global pixel-level fidelity in non-salient regions in order to preserve semantic and structural fidelity within regions of interest. AHQIR is evaluated against multiple state-of-the-art quantum image encoding schemes, including FRQI and NEQR, across Brain Tumor MRI and real-world SAR datasets. Experimental results demonstrate substantial reductions in gate count and improved robustness under realistic noise models, while maintaining reconstruction errors below clinically and analytically relevant thresholds for salient regions. These findings indicate that saliency-aware, selective state preparation offers a practical and scalable pathway for quantum.
Quantum image representation (QIR) is the basic idea behind quantum image processing. It explains how a normal image is converted into quantum states so that it can be processed using quantum computers. The commonly used models for QIR are Flexible Representation of Quantum Images (FRQIs) and Novel Enhanced Quantum Representation (NEQR). Though these approaches highlight the potential of quantum-based image encoding, the limitation of practical applicability on Noisy Intermediate-Scale Quantum (NISQ) devices exists. In this paper, we propose an intensity-preserving quantum image representation (IP-QIR) scheme that aims to maintain accurate grayscale intensity information while significantly reducing quantum resource usage. The proposed method employs a controlled rotation-based encoding strategy, where pixel intensities are embedded into the measurement probability of a single intensity qubit, and spatial information is represented using position qubits. To further enhance feasibility on near-term quantum hardware, the framework operates on small image patches instead of full-resolution images, thereby reducing circuit depth and overall complexity. The performance of the proposed IP-QIR approach is evaluated through IBM Qiskit simulations on three types of grayscale images: synthetic image patches, synthetic aperture radar (SAR) images, and medical tuberculosis (TB) chest X-ray images. Experimental results demonstrate that IP-QIR achieves better intensity preservation than FRQIs and NEQR, with fidelity values reaching up to 84.12% for both SAR and medical datasets. In addition, IP-QIR represents a 4×4 image patch using only five qubits, which significantly reduces the qubit requirement when compared to NEQR, while still preserving high reconstruction accuracy.
Superposition, entanglement, and quantum parallelism can be utilized in Quantum Image Processing (QIP) as a promising paradigm for expediting large-scale visual computing workloads. However, the majority of existing content-agnostic Quantum Image Representation (QIR) models allocate an equal amount of computational resources to individual pixels, irrespective of their semantic significance. This approach poses particular challenges to Noisy Intermediate-Scale Quantum (NISQ) systems, especially in noise-sensitive applications such as medical imaging and maritime surveillance, where low coherence and noisy gates significantly constrain the achievable circuit depth. In order to apply dynamically local resource assignment conditions by the complexity of the image, this paper presents EBA-QR (Entropy-Based Adaptive Quantum Representation), a content- sensitive encoding scheme, which combines a local Shannon entropy scheme and quantum circuit synthesis. EBA-QR does not process the pixels as equals but divides the image into discrete blocks, calculates the number of pixels in each block, and the block entropy, then uses a threshold, which is adjustable, below which each block is considered to be part of Interest (ROI), or the background. In contrast to low- entropy background blocks, which are coded with gate-skipping algorithms to approximate a fixed cost of a gate per block, high- entropy blocks are coded with the NEQR-like basis-state accuracy. The total cost of preparation is proportional to the size of the regions of ROI, and a formal gate-cost optimization function can also be applied to work with a reduction of up to two orders of magnitude compared to NEQR in sparse sceneries without increasing the number of qubits. These benefits are observed to be the effect of entropy-directed gate allocation, not necessarily of classical masking by an Entropy-Based Mask (EBM) control of a NEQR +Mask control baseline that retains the normal NEQR circuit. There are three datasets that were applied as SAR ship detection imaging based on SSDD, brain tumor MRI scans, and so on. Images of Doha International Airport and ICEYE SAR are benchmarked and tested on 10 performance parameters. The development of Qiskit simulators is accomplished. Circuit and all graphics are downsampled to 32 x 32 so as to look NISQ-era. The findings indicate that EBA-QR possesses the fidelity of the level of NEQR in ROIs and is not prone to common aberrations of transform-based compression schemes, and by a maximum of 78.1 percent on sparse SAR sceneries, simplifying the complexity of gates. 64.7% on brain MRI. Moreover, EBA-QR consents that it is helpful. End to-End image processing system in the NISQ era and a successful building block in future quantum pipelines, edge detection, and medical diagnostics satellite monitoring to help in basic operations on images, like geometric transform, image flipping, and Sobel edge detection.
Accurate and computationally efficient classification of brain tumors from MRI scans is critical for deployment in resource-constrained clinical settings, where conventional deep CNN architectures-despite achieving strong accuracy-often require large parameter counts that limit scalability. This work proposes a hybrid quantum-classical deep learning framework that combines a classical convolutional feature extractor with a variational quantum circuit (VQC) for multi-class tumor classification. Spatial features extracted by the CNN backbone will be dimensionality-reduced and encoded into quantum states using angle encoding; a parameterized quantum circuit will then process these features in a higher-dimensional Hilbert space, leveraging superposition and entanglement to capture non-linear feature correlations. Measurement outputs from the quantum layer will be passed to a classical fully connected layer for classification into glioma, meningioma, pituitary tumor, and no-tumor categories. The proposed framework will be evaluated on a publicly available benchmark MRI dataset and benchmarked against state-of-the-art classical CNN architectures in terms of accuracy, precision, recall, F1-score, and parameter efficiency. This study aims to demonstrate that quantum-enhanced layers can achieve competitive classification performance while substantially reducing trainable parameters, offering a practical direction for efficient, quantum-assisted medical image analysis.
Quantum Image Representation (QIR) has become a key component of Quantum Image Processing (QIP), enabling the encoding and manipulation of visual data within quantum computing environments.Its integration with Quantum Artificial Intelligence (QAI) and Quantum Machine Learning (QML) has attracted significant research interest due to the potential advantages of quantum parallelism and compact data representation.This survey reviews major QIR techniques, analyzes their encoding strategies and computational characteristics, and examines their opportunities, challenges, and future relevance in quantum AI and machine learning applications.A systematic review of 70 peer-reviewed journal and conference publications published between 1992 and 2025 was conducted.The selected studies were evaluated based on encoding mechanisms, qubit requirements, circuit complexity, retrieval capability, scalability, and suitability for quantum image processing and learning tasks.The review covers prominent QIR models, including FRQI, NEQR, MCQI, QPIE, GQIR, QRMW, and tensor-network-based representations.Comparative analysis reveals important trade-offs between qubit efficiency, encoding complexity, retrieval accuracy, and scalability.Amplitude-based approaches provide compact image encoding but suffer from probabilistic retrieval, whereas basis-state representations offer deterministic recovery at the expense of increased circuit complexity.QIR demonstrates significant potential in image classification, feature extraction, image compression, and hybrid quantum-classical learning frameworks.QIR provides a promising foundation for next-generation quantum-enhanced visual intelligence systems.However, practical implementation remains constrained by state preparation overhead, noise, decoherence, limited qubit availability, and the lack of standardized evaluation frameworks.Future research should focus on scalable encoding methods, fault-tolerant quantum architectures, benchmarking standards, and deeper integration with advanced QML models to accelerate the development of practical quantum image analytics.
Abstract Color images (i.e. RGB) contain rich visual information essential for object recognition, spatial context analysis, and decision-making across fields such as medical imaging, remote sensing, and computer vision. Processing such data efficiently requires significant computational resources, which can be addressed by the parallelism and speed of quantum computing. Representing RGB image data within quantum states enables efficient and scalable processing compared to classical methods. In recent years, various quantum image representation techniques have been developed based on probabilistic and basis state encoding. Probabilistic encoding methods are efficient for representing quantum binary images but face challenges in accurately reconstructing RGB images. This is due to the randomness introduced by measurement. To overcome this limitation, several basis state encoding approaches have been proposed. These methods map classical pixel values directly to quantum basis states. Thus enabling accurate grayscale and RGB image representation. However, they often require a larger number of qubits and complex gate operations, leading to higher circuit preparation costs. So, there exists substantial potential for quantum probabilistic RGB image representation using randomized measurements. Hence, our objective is to develop a probabilistic quantum image representation, capable of representing RGB images using fewer qubits. This method aims to reconstruct the classical image with high accuracy using randomized measurements, thereby addressing the major limitations of probabilistic methods. To balance image quality with resource efficiency, we propose an Improved Probabilistic Quantum Image Representation (IPQIR) method based on equal superposition states. This approach utilizes a quantum circuit with Hadamard Gate to encode classical pixel values into equal superposition states. The original image is then reconstructed by performing multiple quantum measurements and applying expectation value estimation to average the outcomes. To align with existing research in quantum image representation, quantum state tomography and different applications are utilized as standard evaluation methods to assess the effectiveness of the proposed algorithm. The tomography achieved a fidelity of 97.51%. In addition, various parametric and non-parametric statistical tests were performed to verify the accuracy of the reconstructed classical image. The high Pearson (0.9983) and Spearman (0.9959) correlation coefficients indicate a nearly perfect linear and monotonic relationship between the original and reconstructed images.