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Research – Innovation – Innovative Entrepreneurship: International Scientific Congress

Using the coherence proprieties of light in the control processes in biomolecular systems

Marina Ţurcan

Published Jan 1, 2025• 0 citations
Publisher

Abstract

It is particularly important by now to apply the coherent light proprieties in process control from biomolecular system. In this way, the present report has two basic aspects of the interaction of light with the substance are discussed: the nonlinear one of light interaction with the environment, and the cooperative aspect of interaction of photons with matter in specially biomolecules. Another goal of this work is the presentasions and analysys oh the hydrogen bonds between the Guanine - Cytosine (G-C) and behavior of these nucleotide during the Raman processes. Developed on the basis of experimental evidence, the model incorporates the local symmetry inherent in biomolecular structures. The photons transformation and statistic is presented for the control in the biomolecular systems.

DOI
10.46727/c.v2.07-08-06-2025.p386-395

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It is particularly important by now to apply the coherent light proprieties in process control from biomolecular system. In this way, the present report has two basic aspects of the interaction of light with the substance are discussed: the nonlinear one of light interaction with the environment, and the cooperative aspect of interaction of photons with matter in specially biomolecules. Another goal of this work is the presentasions and analysys oh the hydrogen bonds between the Guanine - Cytosine (G-C) and behavior of these nucleotide during the Raman processes. Developed on the basis of experimental evidence, the model incorporates the local symmetry inherent in biomolecular structures. The photons transformation and statistic is presented for the control in the biomolecular systems.
It is particularly important by now to apply the light in processing and development of modern diagnostic. Here with, two basic aspects of the interaction of light with the substance are discussed: the nonlinear one of light interaction with the environment, and the cooperative aspect of interaction of photons with matter (atoms or biomolecules). One should mention the use of metamaterials for tissue decontamination where the specific form of contact surface plays an important role. Another goal of the present work is the study and use of the cooperative effects of bacteria and viruses located in the evanescent field of biomaterials during Raman interaction of light in ultraviolet region. A model is proposed based upon existing experiments which takes into account the local symmetry of biomolecules. New models emerging from the non-linear interaction of the atomic (molecular) subsystem and the electromagnetic field of cavity could be elaborated. The photons statistic is proposed for the diagnosis of the new collective processes.
The goal of the present work is the study and use of the cooperative effects of bacteria located in the evanescent field of biomaterials during Raman interaction of the light in UV region. A model is proposed based upon existing experiments, which takes into account the local symmetry of biomolecules. In this paper is presented the quantum correlations which can be obtained in the processes of Raman scattering in two photon lasing. An interesting behavior of Stokes and anti-Stokes generated field in the Raman processes can be observed for the small number of pump field in nonlinear media. The photons statistic is proposed for the diagnosis of the new collective processes. The set of functions was presented, which describes the probability of simultaneous existence of (2j + 1) Dicke states in the scattering process.Metamaterials with periodical structures like quartz or glass small granules irradiated by ultraviolet-C (UV-C) to act against microbial contamination of translucent liquids and gases are studied. Investigations of the modifications of individual metamaterial elements when UV evanescent waves are dispersed in the optical contact zone, as a function of granule geometry, were performed. Different situations were investigated, when quartz (SiO2), glass, or black (plastic) materials with dimensions of about 0.5–3 mm are separately placed into a quartz tube of about 2.7 cm diameter and 90 cm length, named “core tube”. Quartz granules transmit within the (240–400 nm) region of the Hg lamp and ensure an effective decontamination of translucent liquids and gases. Our approach is based upon the increased transfer of UV radiation via evanescent waves in case of unordered metamaterials present in contaminated fluids. We made a series of estimations of the decontamination rate of this type of metamaterials vs. ordered metamaterials consisting of spherical elements. Experiments have convincingly demonstrated that both quartz and glass metamaterials can effectively annihilate Coliform (including Escherichia coli) or Enterococcus bacteria. Control experiments were performed in the absence of metamaterials and/or UV-C irradiation.
A semi-classical model (classical by the field and quantum by describing biomolecules) is proposed, which establishes the dependence of the DNA/RNA dimerization rate on ultraviolet C (UVC) radiation intensity. The two types of cooperative effects between the converted photons in these multiple steps of Raman lasing are proposed. The first type involves the cooperative process between the photons of one of the steps of Raman conversion. The second cooperative effect appears between the photons belonging to different steps of multiple conversions. This new type of generated coherent state is proposed by novel bimodal entangled sources, which take into consideration both the coherence and collective phenomena between the photons belonging to the system of the bimodal field obtained in multiple Raman emission. The application of higher-order multiple Roman bimodal coherent field quantum information is described in accordance with the definition of quantum amplitude and phase of such entangled states of light.
Modern quantum optics encompasses a wide field of phenomena that are either related to the discrete quantum nature of light, the quantum wave nature of matter or light-matter interactions.We here discuss new perspectives for quantum optics with biological nanoparticles.We focus in particular on the prospects of matter-wave interferometry with amino acids, nucleotides, polypeptides or DNA strands.We motivate the challenge of preparing these objects in a 'biomimetic' environment and argue that hydrated molecular beam sources are promising tools for quantum-assisted metrology.The method exploits the high sensitivity of matter-wave interference fringes to dephasing and shifts in the presence of external perturbations to access and determine molecular properties.
Our recently proposed quantum approach to biomolecular recognition processes is hereby additionally supported by biomolecular Resonant Recognition Model and by quantum-chemical theory of biomolecular non-radiative resonant transitions. Previously developed general quantumdecoherence framework for biopolymer conformational changes in very selective ligandproteins/ target-receptors key/lock biomolecular recognition processes (with electron-conformational coupling, giving rise to dynamical modification of many-electron energy-state hypersurface of the cellular quantum-ensemble ligand-proteins/target-receptors biomolecular macroscopic quantum system, with revealed possibility to consider cellular biomolecular recognition as a Hopfield-like quantum-holographic associative neural network) is further extended from nonlocal macroscopicquantum level of biological cell to nonlocal macroscopic-quantum level of biological organism, based on long-range coherent microwave excitations (as supported by macroscopic quantum-like microwave resonance therapy of the acupuncture system) - which might be of fundamental importance in understanding of underlying macroscopic quantum (quantum-holographic Hopfieldlike) control mechanisms of embryogenesis/ontogenesis and morphogenesis, and their backward influence on the expression of genes.
Our understanding of the physics of biological molecules, such as proteins and DNA, is limited because the approximations we usually apply to model inert materials are not, in general, applicable to soft, chemically inhomogeneous systems. The configurational complexity of biomolecules means the entropic contribution to the free energy is a significant factor in their behaviour, requiring detailed dynamical calculations to fully evaluate. Computer simulations capable of taking all interatomic interactions into account are therefore vital. However, even with the best current supercomputing facilities, we are unable to capture enough of the most interesting aspects of their behaviour to properly understand how they work. This limits our ability to design new molecules, to treat diseases, for example. Progress in biomolecular simulation depends crucially on increasing the computing power available. Faster classical computers are in the pipeline, but these provide only incremental improvements. Quantum computing offers the possibility of performing huge numbers of calculations in parallel, when it becomes available. We discuss the current open questions in biomolecular simulation, how these might be addressed using quantum computation and speculate on the future importance of quantum-assisted biomolecular modelling.