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International Conference on Automation, Computing and Renewable Systems (ICACRS)

Hybrid Quantum and AI Techniques for Ophthalmology Drug Discovery and Early Diagnosis

V. Durgadevi, N. Subbulakshmi

Published Dec 10, 2025• 0 citations
Publisher

Abstract

Recent breakthroughs in medical computational modelling, particularly in ophthalmology, have produced remarkable achievements in disease identification and classification with the aid of deep learning and hybrid quantum–classical methods. Though the current ensemble CNNs have more than 99% accuracy in diagnosing glaucoma, diabetic retinopathy, and other retinal diseases, scalability and interpretability remain problematic. This paper presents a novel hybrid quantum–classical approach that combines quantum feature encoding with ensemble CNNs optimised to improve diagnostic accuracy and lower computational burden. The new model exhibits higher feature extraction efficiency and noise robustness than traditional architectures. Through the use of quantum state representations, the system enables better decision-making, prediction, and personalised therapy suggestions. Integrated automated analysis of behaviour in this system also supports real-time identification and adaptive treatment planning.In general, the main innovation is the integration of quantum encoding and ensembles of deep learning for the classification of ophthalmic disease, providing a scalable avenue toward intelligent, real-time healthcare analysis.

DOI
10.1109/icacrs67045.2025.11324135

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Traditional convolutional neural networks (CNNs) have shown potential for recognizing retinopathy caused by diabetes (DR). However, developing quantum computing has the possibility for improved feature representation. We propose a hybrid approach that combines classical CNNs with quantum circuits to capitalize on both classical and quantum information for DR classification. Using the Keras and Qiskit frameworks, our model encodes picture features into quantum states, allowing for richer representations. Through experiments on a collection of retinal pictures, our model displays competitive performance, with excellent reliability and precision in categorizing DR severity levels. This combination of classical and quantum paradigms offers a fresh approach to enhancing DR diagnosis and therapy.
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