Multiple Raman Coherent Process in Generation of Biomolecular Complexes

Abstract

This chapter introduces an optical framework for the generation of molecular superstructures from tertiary components through Raman-induced interactions with a bimodal cavity field. A nonlinear model is developed based on cooperative processes analogous to multiple Raman scattering and their integration with biomolecular assemblies. Particular attention is given to phase transitions leading to the formation of supramolecular structures, where induced Raman excitation enables the stabilization of multimeric states such as dimers, trimers, tetramers, and pentamers. The proposed master equation describes the synthesis and stabilization of such structures under Raman excitation. Importantly, the model can also be applied inversely, where large molecular aggregates are dissociated into smaller components via induced multiple Raman scattering. This dual mechanism provides a theoretical basis for designing highly efficient optical metamaterials with potential applications in advanced decontamination technologies. To illustrate the applicability, experimental investigations were performed using yeast fungi as a surrogate for more sensitive pathogens (viruses and bacteria). The results revealed two distinct decontamination regimes under nanosecond-pulsed ultraviolet C radiation, consistent with the predictions of the multiple Raman dimerization model. These findings highlight the potential of Raman-driven cooperative processes in both molecular synthesis and selective pathogen inactivation.