As a degenerative disease that seriously affects the central nervous system, early diagnosis of Parkinson's disease is important for slowing down the course of the disease and improving patients' quality of life.In recent years, machine learning has shown great potential in medical data analysis, and support vector machines (SVMs) are widely used in classification and prediction tasks.However, traditional SVMs have some limitations in high dimensionality and complex data processing.With the rapid development of quantum computing, quantum support vector machines (QSVMs) have become an emerging technology that has attracted much attention due to its ability to process largescale data and its potential for modeling high-dimensional features.In this paper, we compare traditional SVMs and QSVMs in the analysis of Parkinson's disease data, and evaluate their performance in terms of classification accuracy.The experiments are conducted on a publicly available dataset and analyzed in detail through the steps of model construction, data preprocessing, algorithm implementation, and performance evaluation.The results show that QSVM outperforms traditional SVM in complex feature space, which demonstrates its potential advantages and application prospects in medical data analysis.
As a degenerative disease that seriously affects the central nervous system, early diagnosis of Parkinson's disease is important for slowing down the course of the disease and improving patients' quality of life.In recent years, machine learning has shown great potential in medical data analysis, and support vector machines (SVMs) are widely used in classification and prediction tasks.However, traditional SVMs have some limitations in high dimensionality and complex data processing.With the rapid development of quantum computing, quantum support vector machines (QSVMs) have become an emerging technology that has attracted much attention due to its ability to process largescale data and its potential for modeling high-dimensional features.In this paper, we compare traditional SVMs and QSVMs in the analysis of Parkinson's disease data, and evaluate their performance in terms of classification accuracy.The experiments are conducted on a publicly available dataset and analyzed in detail through the steps of model construction, data preprocessing, algorithm implementation, and performance evaluation.The results show that QSVM outperforms traditional SVM in complex feature space, which demonstrates its potential advantages and application prospects in medical data analysis.
Parkinson’s disease (PD) is a progressive neurodegenerative disorder affecting millions worldwide, where early and accurate diagnosis plays a critical role in improving patient outcomes. While classical machine learning methods have shown strong performance in PD classification using clinical and acoustic data, they remain limited in capturing complex nonlinear feature interactions in high-dimensional spaces. This study explores the application of quantum machine learning (QML) techniques for PD prediction, focusing on Variational Quantum Classifiers (VQC) and Quantum Support Vector Machines (QSVM), and compares their performance with strong classical baselines including Logistic Regression, SVM, Random Forest, Grid Search–optimized models, and XGBoost. Experiments were conducted using stratified train–test splits and validated through cross-validation and statistical testing. Results show that classical models achieve competitive performance, with XGBoost reaching 91.9% accuracy. However, quantum models demonstrate slightly improved performance, with the VQC using EfficientSU2 achieving the highest accuracy of 93.1%, followed by the Real Amplitudes VQC (92.6%) and QSVM (92.2%). These improvements are consistent across evaluation metrics including F1-score and recall. Statistical analysis using 10-fold cross-validation indicates that the VQC (EfficientSU2) shows a significant improvement over classical baselines ( p = 0.031), while other quantum models do not achieve statistical significance over XGBoost ( p > 0.05). McNemar’s test on the independent test set confirms no significant difference in final prediction distributions between quantum and classical models. Overall, the findings suggest that quantum machine learning models are competitive with state-of-the-art classical approaches, offering marginal but consistent performance gains. This study highlights the potential of quantum-enhanced learning frameworks for biomedical classification tasks, while also emphasizing that their advantages remain incremental rather than definitive under current simulation-based implementations.
The prompt detection of neurodegenerative diseases (NDDs) like Alzheimer's Disease (AD), Mild Cognitive Impairment (MCI), and Parkinson's Disease (PD) is essential yet difficult. This research proposes a hybrid quantum-classical machine learning methodology to categorize NDD using multimodal brain imaging data.ADNI and PPMI datasets' MRI, PET, and fMRI images were preprocessing by Python-based tools such as Scikit-image, SimpleITK, and FreeSurfer via Nipype. Major steps were denoising, registration, normalization, segmentation, and extraction of features from structural and functional imaging. Training was done with a Quantum Support Vector Machine (QSVM) using Qiskit's ZZFeatureMap and QuantumKernel and compared with a conventional SVM. Performance measures-precision, recall, F1-score, class accuracy, AUC, and 10-fold cross-validation-were calculated. QSVM performed better than the standard SVM on all metrics, with 91.25% overall accuracy and macro F1-score of 0.913 as opposed to 87.75% and 0.879 for the SVM. The results validate QSVM's advantage in handling complex, high-dimensional neuroimaging data and its relevance to aiding clinical diagnosis. Keywords: Quantum Machine Learning, Neuroimaging, QSVM, Alzheimer’s Disease, Parkinson’s Disease, Multimodal Classification
Quantum-assisted machine learning approaches have become a significant area of research in the healthcare domain by offering alternative solutions to classical methods, particularly when dealing with high-dimensional and complex datasets. This study presents a comparative evaluation of the classification performance of classical Support Vector Machines (SVM) and quantum-based algorithms Quantum Support Vector Machine (QSVM) and Pegasos-QSVM on healthcare data. Experimental analyses were conducted using three distinct medical datasets related to liver disease, breast cancer, and heart failure. The results demonstrate that the QSVM model consistently achieved the highest and most stable classification accuracy. Although the Pegasos-QSVM model achieved comparable accuracy rates in certain configurations, its performance was generally more variable. Nevertheless, thanks to its lower computational cost and faster processing time, Pegasos-QSVM emerges as a promising alternative, particularly in resource-constrained environments. The findings suggest that quantum-assisted models can deliver performance levels competitive with classical approaches, particularly highlighting the effectiveness of QSVM on small- to medium-sized datasets.
Effective and accurate diagnosis of diseases such as cancer, diabetes, and heart failure is crucial for timely medical intervention and improving patient survival rates. Machine learning has revolutionized diagnostic methods in recent years by developing classification models that detect diseases based on selected features. However, these classification tasks are often highly imbalanced, limiting the performance of classical models. Quantum models offer a promising alternative, exploiting their ability to express complex patterns by operating in a higher-dimensional computational space through superposition and entanglement. These unique properties make quantum models potentially more effective in addressing the challenges of imbalanced datasets. This work evaluates the potential of quantum classifiers in healthcare, focusing on Quantum Neural Networks (QNNs) and Quantum Support Vector Machines (QSVMs), comparing them with popular classical models. The study is based on three well-known healthcare datasets—Prostate Cancer, Heart Failure, and Diabetes.The results indicate that QSVMs outperform QNNs across all datasets due to their susceptibility to overfitting. Furthermore, quantum models prove the ability to overcome classical models in scenarios with high dataset imbalance. Although preliminary, these findings highlight the potential of quantum models in healthcare classification tasks and lead the way for further research in this domain.
A chronic metabolic disease, diabetes mellitus has become a serious global public health concern. Using the Indian Pima Diabetes Dataset, this study compares Classical Support Vector Machines (CSVM) with Quantum Support Vector Machines (QSVM) for diabetes prediction. To address the challenges associated with high-dimensional data and feature redundancy, before classification, a feature reduction method called Principal Component Analysis (PCA) is used. Experimental results demonstrate that PCA effectively reduces computational complexity while preserving essential information required for classification. Furthermore, the study investigates the potential advantages of quantum-enhanced learning in healthcare prediction tasks by comparing the predictive capabilities and computational characteristics of QSVM against its classical counterpart. The findings provide insights into the applicability of quantum machine learning techniques for medical diagnosis and highlight the opportunities and challenges associated with implementing quantum algorithms on real-world healthcare datasets.
Parkinson's disease (PD) is a progressive neuro-degenerative condition with an urgent need for timely and pinpoint diagnosis for adequate treatment. Despite potential for prediction with traditional machine learning techniques, PD data remains difficult to solve for traditional machine learning techniques due to the high computational complexity and the nature of data. We introduce in this work a Hybrid Quantum-Classical AI Framework that combines advantages of QC and provide benefits in predictive accuracy as well as computational efficiency for real time Parkinson's disease detection. We use classical deep learning models in conjunction with Variational Quantum Circuits (VQC) to perform efficient feature extraction and classification of biomedical signals: speech and its recordings, gait analysis, and EEG data. We evaluate the performance of our proposed framework against deep learning models that are standard and based on the accuracy, precision, recall and processing time. Our experimental results suggest that our hybrid quantum classical model outperforms classical methods for both accuracy and efficiency, demonstrating the potential of quantum machine learning (QML) in healthcare. This work gives a taste of the quantum revolution realized in medical diagnostics and paves the way for what could in the future be quantum enhanced disease prediction.