Challenges
Datasets
Workspaces
Papers
Discussions
Leaderboard
Log inSign up
Challenges
Datasets
Workspaces
Papers
Discussions
Leaderboard
Blog
Job Board
Q3AS

© 2026 Aqora Quantum S.A.S.

TermsPrivacyLegal Notice

Uluslararası sürdürülebilir mühendislik ve teknoloji dergisi.

COMPARATIVE ANALYSIS OF CLASSICAL AND QUANTUM SVM MODELS ON MEDICAL DIAGNOSIS DATASETS

Gamzepelin Aksoy, Zeynep Özpolat

Published Jun 30, 2025• 3 citations
Publisher

Abstract

Quantum-assisted machine learning approaches have become a significant area of research in the healthcare domain by offering alternative solutions to classical methods, particularly when dealing with high-dimensional and complex datasets. This study presents a comparative evaluation of the classification performance of classical Support Vector Machines (SVM) and quantum-based algorithms Quantum Support Vector Machine (QSVM) and Pegasos-QSVM on healthcare data. Experimental analyses were conducted using three distinct medical datasets related to liver disease, breast cancer, and heart failure. The results demonstrate that the QSVM model consistently achieved the highest and most stable classification accuracy. Although the Pegasos-QSVM model achieved comparable accuracy rates in certain configurations, its performance was generally more variable. Nevertheless, thanks to its lower computational cost and faster processing time, Pegasos-QSVM emerges as a promising alternative, particularly in resource-constrained environments. The findings suggest that quantum-assisted models can deliver performance levels competitive with classical approaches, particularly highlighting the effectiveness of QSVM on small- to medium-sized datasets.

DOI
10.62301/usmtd.1716034

Related papers

Quantum Machine Learning in Healthcare: Evaluating QNN and QSVM Models

Antonio Tudisco, Deborah Volpe, Giovanna Turvani

Effective and accurate diagnosis of diseases such as cancer, diabetes, and heart failure is crucial for timely medical intervention and improving patient survival rates. Machine learning has revolutionized diagnostic methods in recent years by developing classification models that detect diseases based on selected features. However, these classification tasks are often highly imbalanced, limiting the performance of classical models. Quantum models offer a promising alternative, exploiting their ability to express complex patterns by operating in a higher-dimensional computational space through superposition and entanglement. These unique properties make quantum models potentially more effective in addressing the challenges of imbalanced datasets. This work evaluates the potential of quantum classifiers in healthcare, focusing on Quantum Neural Networks (QNNs) and Quantum Support Vector Machines (QSVMs), comparing them with popular classical models. The study is based on three well-known healthcare datasets—Prostate Cancer, Heart Failure, and Diabetes.The results indicate that QSVMs outperform QNNs across all datasets due to their susceptibility to overfitting. Furthermore, quantum models prove the ability to overcome classical models in scenarios with high dataset imbalance. Although preliminary, these findings highlight the potential of quantum models in healthcare classification tasks and lead the way for further research in this domain.

arXiv:2505.20804•International Joint Conference on Neural Networks (IJCNN)•Jun 30, 2025•9 citations

Conventional Support Vector Machines vs. Quantum Support Vector Machines in Parkinson’s Comparative studies in the analysis of disease data

Zixiu Li

As a degenerative disease that seriously affects the central nervous system, early diagnosis of Parkinson's disease is important for slowing down the course of the disease and improving patients' quality of life.In recent years, machine learning has shown great potential in medical data analysis, and support vector machines (SVMs) are widely used in classification and prediction tasks.However, traditional SVMs have some limitations in high dimensionality and complex data processing.With the rapid development of quantum computing, quantum support vector machines (QSVMs) have become an emerging technology that has attracted much attention due to its ability to process largescale data and its potential for modeling high-dimensional features.In this paper, we compare traditional SVMs and QSVMs in the analysis of Parkinson's disease data, and evaluate their performance in terms of classification accuracy.The experiments are conducted on a publicly available dataset and analyzed in detail through the steps of model construction, data preprocessing, algorithm implementation, and performance evaluation.The results show that QSVM outperforms traditional SVM in complex feature space, which demonstrates its potential advantages and application prospects in medical data analysis.

Advances in computer science research•Jan 1, 2025•0 citations

Comparing Classical and Quantum Machine Learning Models for Breast Cancer Classification on the WDBC Dataset

Jovana Gluhovic

Breast cancer is a major health concern, and early detection can make a great difference in treatment and survival rates for breast cancer patients. Machine learning methods have noticeably improved prediction accuracy on high-dimensional medical datasets and have become widely used tools in medical diagnostics. The transition to a quantum computational framework has opened new directions in machine learning research. By using qubits instead of classical bits, quantum models may provide new ways to represent and process complex medical data. In medical diagnostics, this has led to a growing interest in whether quantum approaches can improve classification performance more effectively than classical methods. The purpose of this paper is to compare classical and quantum machine learning models on the task of breast cancer classification and to determine whether quantum models can achieve higher accuracy and faster prediction on a selected dataset. Alongside the main simulator-based experiment, a smaller experiment was performed on a real IBM quantum computer to demonstrate the practical execution of the same task under current hardware constraints. In the practical part of the study, the Wisconsin Diagnostic Breast Cancer (WDBC) dataset was used. This dataset consists of 569 samples with 30 numerical features extracted from digitized fine needle aspirate images and provides a reliable basis for evaluating model performance. A comparative analysis was conducted between classical and quantum machine learning models, including a support vector machine (SVM), an artificial neural network (ANN), a quantum support vector machine (QSVM), and a hybrid quantum-classical neural network (QNN). In the simulator-based experiment, both SVM and ANN achieved an accuracy of 0.956 with an F1-score of 0.965 on the test set, while QSVM reached an accuracy of 0.807 with an F1-score of 0.866 and the Hybrid QNN achieved 0.623 accuracy with an F1-score of 0.677. These quantum and hybrid models also required substantially longer training times than the classical baselines. A small hardware experiment on an IBM quantum device further illustrates both the practical feasibility and the current limitations of executing this classification task on noisy intermediate-scale quantum hardware.

American Journal of Computer Science and Technology•Aug 6, 2026•0 citations

Comparative Performance Analysis of SVM and QSVM in Breast Cancer Diagnosis

Gita Kartika, Muhamad Akrom

The application of machine learning has shown significant progress in various fields, including clinical data classification. This study presents a comparative analysis between the classical Support Vector Machine (SVM) and Quantum Support Vector Machine (QSVM) for breast cancer classification using the Wisconsin Diagnostic Breast Cancer (WDBC) dataset. Principal Component Analysis (PCA) was applied as dimension reduction strategy across three configurations (PCA = 2, PCA = 4, and PCA = 6) to evaluate the sensitivity of both models to the feature space dimension. Preprocessing included log1p transformation on 22 skewed features, Manual SMOTE balancing, and MinMaxScaler normalization. SVM was optimized via GridSearchCV (80 parameter combinations, cv = 5), while QSVM employed a ZZFeatureMap quantum kernel (reps = 2, entanglement = full) on qasm_simulator. Experimental results demonstrate that SVM achieved superior accuracy across all configurations, with peak performance at PCA = 6 (Accuracy= 98.83%, AUC = 0.9985, Specificity = 1.0000, Sensitivity = 0.9688, Precision = 1.0000, NPV = 0.9817, and F1-score for malignant = 0.98). QSVM achieved its highest accuracy at PCA = 4 (92.98%), AUC = 0.9622, Sensitivity = 0.9219, Precision = 0.8939, NPV = 0.9524, and F1-score for malignant = 0.91. Across the three PCA configurations, QSVM exhibited a non-monotonic relationship between PCA dimensions and quantum kernel performance . These findings provide a quantitative benchmark for comparing quantum and classical machine learning in breast cancer diagnosis.

Journal of Applied Informatics and Computing•Oct 18, 2026•0 citations

SARS-CoV-2 Classification Using Classical vs. Quantum Machine Learning: A Performance Comparison of SVM, QSVM, and Pegasos

Sthefanie Jofer Gomes Passo, Muntakim Haque, Vishal H. Kothavade +1 more

Quantum Machine Learning (QML) integrates principles of quantum computation with statistical learning to address classification tasks. This paper conducts a comparative study of three paradigms—classical Support Vector Classification (SVC), Quantum Support Vector Classification (QSVC) using quantum kernels, and QSVC enhanced via the Pegasos stochastic algorithm. We benchmark classification accuracy on a SARS-CoV-2 dataset, analyzing model robustness and resource requirements. Our results indicate that while classical SVC maintains superior scalability and stability for large datasets, QSVC variants show competitive accuracy across simulator backends (Central Processing Units or CPUs and Graphical Processor Units or GPUs) and may achieve quantum advantage as hardware matures. Implications for hybrid workflows and future research directions are discussed.

IEEE International Conference on AI in Cybersecurity (ICAIC)•Feb 18, 2026•3 citations

A Comparative Study of Classical and Variational Quantum Machine Learning Models for Breast Cancer Classification

Divya Guthi

Early and accurate diagnosis of breast cancer plays a critical role in improving patient survival rates and reducing treatment costs. Classical machine learning algorithms such as Logistic Regression and Support Vector Machines (SVM) have demonstrated strong performance in medical diagnosis tasks; however, their scalability and representational limits motivate the exploration of emerging paradigms. Quantum Machine Learning (QML), particularly Variational Quantum Classifiers (VQC), has recently gained attention due to its potential to model complex decision boundaries using quantum circuits. This paper presents a comparative analysis between a Variational Quantum Classifier and classical machine learning models for binary breast cancer classification. The study employs dimensionality-reduced clinical data and evaluates model performance using accuracy, confusion matrices, decision boundary visualization, Principal Component Analysis (PCA), and Receiver Operating Characteristic (ROC) curves. Experimental results indicate that the VQC achieves competitive performance with classical approaches, demonstrating its feasibility for small-scale medical datasets and highlighting the promise of quantum-enhanced learning in healthcare applications.

International Journal of Science and Research (IJSR)•Dec 16, 2025•0 citations
Quantum-assisted machine learning approaches have become a significant area of research in the healthcare domain by offering alternative solutions to classical methods, particularly when dealing with high-dimensional and complex datasets. This study presents a comparative evaluation of the classification performance of classical Support Vector Machines (SVM) and quantum-based algorithms Quantum Support Vector Machine (QSVM) and Pegasos-QSVM on healthcare data. Experimental analyses were conducted using three distinct medical datasets related to liver disease, breast cancer, and heart failure. The results demonstrate that the QSVM model consistently achieved the highest and most stable classification accuracy. Although the Pegasos-QSVM model achieved comparable accuracy rates in certain configurations, its performance was generally more variable. Nevertheless, thanks to its lower computational cost and faster processing time, Pegasos-QSVM emerges as a promising alternative, particularly in resource-constrained environments. The findings suggest that quantum-assisted models can deliver performance levels competitive with classical approaches, particularly highlighting the effectiveness of QSVM on small- to medium-sized datasets.
Effective and accurate diagnosis of diseases such as cancer, diabetes, and heart failure is crucial for timely medical intervention and improving patient survival rates. Machine learning has revolutionized diagnostic methods in recent years by developing classification models that detect diseases based on selected features. However, these classification tasks are often highly imbalanced, limiting the performance of classical models. Quantum models offer a promising alternative, exploiting their ability to express complex patterns by operating in a higher-dimensional computational space through superposition and entanglement. These unique properties make quantum models potentially more effective in addressing the challenges of imbalanced datasets. This work evaluates the potential of quantum classifiers in healthcare, focusing on Quantum Neural Networks (QNNs) and Quantum Support Vector Machines (QSVMs), comparing them with popular classical models. The study is based on three well-known healthcare datasets—Prostate Cancer, Heart Failure, and Diabetes.The results indicate that QSVMs outperform QNNs across all datasets due to their susceptibility to overfitting. Furthermore, quantum models prove the ability to overcome classical models in scenarios with high dataset imbalance. Although preliminary, these findings highlight the potential of quantum models in healthcare classification tasks and lead the way for further research in this domain.
As a degenerative disease that seriously affects the central nervous system, early diagnosis of Parkinson's disease is important for slowing down the course of the disease and improving patients' quality of life.In recent years, machine learning has shown great potential in medical data analysis, and support vector machines (SVMs) are widely used in classification and prediction tasks.However, traditional SVMs have some limitations in high dimensionality and complex data processing.With the rapid development of quantum computing, quantum support vector machines (QSVMs) have become an emerging technology that has attracted much attention due to its ability to process largescale data and its potential for modeling high-dimensional features.In this paper, we compare traditional SVMs and QSVMs in the analysis of Parkinson's disease data, and evaluate their performance in terms of classification accuracy.The experiments are conducted on a publicly available dataset and analyzed in detail through the steps of model construction, data preprocessing, algorithm implementation, and performance evaluation.The results show that QSVM outperforms traditional SVM in complex feature space, which demonstrates its potential advantages and application prospects in medical data analysis.
Breast cancer is a major health concern, and early detection can make a great difference in treatment and survival rates for breast cancer patients. Machine learning methods have noticeably improved prediction accuracy on high-dimensional medical datasets and have become widely used tools in medical diagnostics. The transition to a quantum computational framework has opened new directions in machine learning research. By using qubits instead of classical bits, quantum models may provide new ways to represent and process complex medical data. In medical diagnostics, this has led to a growing interest in whether quantum approaches can improve classification performance more effectively than classical methods. The purpose of this paper is to compare classical and quantum machine learning models on the task of breast cancer classification and to determine whether quantum models can achieve higher accuracy and faster prediction on a selected dataset. Alongside the main simulator-based experiment, a smaller experiment was performed on a real IBM quantum computer to demonstrate the practical execution of the same task under current hardware constraints. In the practical part of the study, the Wisconsin Diagnostic Breast Cancer (WDBC) dataset was used. This dataset consists of 569 samples with 30 numerical features extracted from digitized fine needle aspirate images and provides a reliable basis for evaluating model performance. A comparative analysis was conducted between classical and quantum machine learning models, including a support vector machine (SVM), an artificial neural network (ANN), a quantum support vector machine (QSVM), and a hybrid quantum-classical neural network (QNN). In the simulator-based experiment, both SVM and ANN achieved an accuracy of 0.956 with an F1-score of 0.965 on the test set, while QSVM reached an accuracy of 0.807 with an F1-score of 0.866 and the Hybrid QNN achieved 0.623 accuracy with an F1-score of 0.677. These quantum and hybrid models also required substantially longer training times than the classical baselines. A small hardware experiment on an IBM quantum device further illustrates both the practical feasibility and the current limitations of executing this classification task on noisy intermediate-scale quantum hardware.
The application of machine learning has shown significant progress in various fields, including clinical data classification. This study presents a comparative analysis between the classical Support Vector Machine (SVM) and Quantum Support Vector Machine (QSVM) for breast cancer classification using the Wisconsin Diagnostic Breast Cancer (WDBC) dataset. Principal Component Analysis (PCA) was applied as dimension reduction strategy across three configurations (PCA = 2, PCA = 4, and PCA = 6) to evaluate the sensitivity of both models to the feature space dimension. Preprocessing included log1p transformation on 22 skewed features, Manual SMOTE balancing, and MinMaxScaler normalization. SVM was optimized via GridSearchCV (80 parameter combinations, cv = 5), while QSVM employed a ZZFeatureMap quantum kernel (reps = 2, entanglement = full) on qasm_simulator. Experimental results demonstrate that SVM achieved superior accuracy across all configurations, with peak performance at PCA = 6 (Accuracy= 98.83%, AUC = 0.9985, Specificity = 1.0000, Sensitivity = 0.9688, Precision = 1.0000, NPV = 0.9817, and F1-score for malignant = 0.98). QSVM achieved its highest accuracy at PCA = 4 (92.98%), AUC = 0.9622, Sensitivity = 0.9219, Precision = 0.8939, NPV = 0.9524, and F1-score for malignant = 0.91. Across the three PCA configurations, QSVM exhibited a non-monotonic relationship between PCA dimensions and quantum kernel performance . These findings provide a quantitative benchmark for comparing quantum and classical machine learning in breast cancer diagnosis.
Quantum Machine Learning (QML) integrates principles of quantum computation with statistical learning to address classification tasks. This paper conducts a comparative study of three paradigms—classical Support Vector Classification (SVC), Quantum Support Vector Classification (QSVC) using quantum kernels, and QSVC enhanced via the Pegasos stochastic algorithm. We benchmark classification accuracy on a SARS-CoV-2 dataset, analyzing model robustness and resource requirements. Our results indicate that while classical SVC maintains superior scalability and stability for large datasets, QSVC variants show competitive accuracy across simulator backends (Central Processing Units or CPUs and Graphical Processor Units or GPUs) and may achieve quantum advantage as hardware matures. Implications for hybrid workflows and future research directions are discussed.
Early and accurate diagnosis of breast cancer plays a critical role in improving patient survival rates and reducing treatment costs. Classical machine learning algorithms such as Logistic Regression and Support Vector Machines (SVM) have demonstrated strong performance in medical diagnosis tasks; however, their scalability and representational limits motivate the exploration of emerging paradigms. Quantum Machine Learning (QML), particularly Variational Quantum Classifiers (VQC), has recently gained attention due to its potential to model complex decision boundaries using quantum circuits. This paper presents a comparative analysis between a Variational Quantum Classifier and classical machine learning models for binary breast cancer classification. The study employs dimensionality-reduced clinical data and evaluates model performance using accuracy, confusion matrices, decision boundary visualization, Principal Component Analysis (PCA), and Receiver Operating Characteristic (ROC) curves. Experimental results indicate that the VQC achieves competitive performance with classical approaches, demonstrating its feasibility for small-scale medical datasets and highlighting the promise of quantum-enhanced learning in healthcare applications.