Error mitigation techniques are crucial to achieving near-term quantum advantage. Classical post-processing of quantum computation outcomes is a popular approach for error mitigation, which includes methods such as Zero Noise Extrapolation, Virtual Distillation, and learning-based error mitigation. However, these techniques have limitations due to the propagation of uncertainty resulting from the finite shot number of a quantum measurement. In this work, we introduce general and unbiased methods for quantifying the uncertainty and error of error-mitigated observables based on the strategic sampling of error mitigation outcomes. We then extend our approach to demonstrate the optimization of performance and robustness of error mitigation under uncertainty. To illustrate our methods, we apply them to Zero Noise Extrapolation and Clifford Date Regression in the ground state of the XY model simulated using depolarizing and IBM Toronto noise models, respectively. In particular, we optimize the choice of noise levels and the allocation of shots for Zero Noise Extrapolation and the distribution of the training circuits for Clifford Data Regression. While our methods are readily applicable to any post-processing-based error mitigation approach, in practice they must not be prohibitively expensive – even though they perform optimizations of the error mitigation hyperparameters requiring sampling of a statistical distribution of error mitigation outcomes. By leveraging surrogate-based optimization, we show that our methods can efficiently perform optimal design for a Zero Noise Extrapolation implementation. We then further demonstrate the transferability of learned Zero Noise Extrapolation hyperparameters to other similar circuits.
Error mitigation techniques are crucial to achieving near-term quantum advantage. Classical post-processing of quantum computation outcomes is a popular approach for error mitigation, which includes methods such as Zero Noise Extrapolation, Virtual Distillation, and learning-based error mitigation. However, these techniques have limitations due to the propagation of uncertainty resulting from the finite shot number of a quantum measurement. In this work, we introduce general and unbiased methods for quantifying the uncertainty and error of error-mitigated observables based on the strategic sampling of error mitigation outcomes. We then extend our approach to demonstrate the optimization of performance and robustness of error mitigation under uncertainty. To illustrate our methods, we apply them to Zero Noise Extrapolation and Clifford Date Regression in the ground state of the XY model simulated using depolarizing and IBM Toronto noise models, respectively. In particular, we optimize the choice of noise levels and the allocation of shots for Zero Noise Extrapolation and the distribution of the training circuits for Clifford Data Regression. While our methods are readily applicable to any post-processing-based error mitigation approach, in practice they must not be prohibitively expensive – even though they perform optimizations of the error mitigation hyperparameters requiring sampling of a statistical distribution of error mitigation outcomes. By leveraging surrogate-based optimization, we show that our methods can efficiently perform optimal design for a Zero Noise Extrapolation implementation. We then further demonstrate the transferability of learned Zero Noise Extrapolation hyperparameters to other similar circuits.
The pursuit of practical quantum utility on near-term quantum processors is critically challenged by their inherent noise. Quantum error mitigation (QEM) techniques are leading solutions to improve computation fidelity with relatively low qubit-overhead, while full-scale quantum error correction remains a distant goal. However, QEM techniques incur substantial measurement overheads, especially when applied to families of quantum circuits parameterized by classical inputs. Focusing on zero-noise extrapolation (ZNE), a widely adopted QEM technique, here we devise the surrogate-enabled ZNE (S-ZNE), which leverages classical learning surrogates to perform ZNE entirely on the classical side. Unlike conventional ZNE, whose measurement cost scales linearly with the number of circuits, S-ZNE requires only constant measurement overhead for an entire family of quantum circuits, offering superior scalability. Theoretical analysis indicates that S-ZNE achieves accuracy comparable to conventional ZNE in many practical scenarios, and numerical experiments on up to 100-qubit ground-state energy and quantum metrology tasks confirm its effectiveness. Our approach provides a template that can be effectively extended to other quantum error mitigation protocols, opening a promising path toward scalable error mitigation.
Error mitigation is essential for the practical implementation of quantum algorithms on noisy intermediate-scale quantum (NISQ) devices. This work explores and extends Clifford Data Regression (CDR) to mitigate noise in quantum chemistry simulations using the Variational Quantum Eigensolver (VQE). Using the H4 molecule with the tiled Unitary Product State (tUPS) ansatz, we perform noisy simulations with the ibm torino noise model to investigate in detail the effect of various hyperparameters in CDR on the error mitigation quality. Building on these insights, two improvements to the CDR framework are proposed. The first, Energy Sampling (ES), improves performance by selecting only the lowest-energy training circuits for regression, thereby further biasing the sample energies toward the target state. The second, Non-Clifford Extrapolation (NCE), enhances the regression model by including the number of non-Clifford parameters as an additional input, enabling the model to learn how the noisy-ideal mapping evolves as the circuit approaches the optimal one. Our numerical results demonstrate that both strategies outperform the original CDR.
Error mitigation is an essential component of achieving a practical quantum advantage in the near term, and a number of different approaches have been proposed. In this work, we recognize that many state-of-the-art error mitigation methods share a common feature: they are data-driven, employing classical data obtained from runs of different quantum circuits. For example, Zero-noise extrapolation (ZNE) uses variable noise data and Clifford-data regression (CDR) uses data from near-Clifford circuits. We show that Virtual Distillation (VD) can be viewed in a similar manner by considering classical data produced from different numbers of state preparations. Observing this fact allows us to unify these three methods under a general data-driven error mitigation framework that we call UNIfied Technique for Error mitigation with Data (UNITED). In certain situations, we find that our UNITED method can outperform the individual methods (i.e., the whole is better than the individual parts). Specifically, we employ a realistic noise model obtained from a trapped ion quantum computer to benchmark UNITED, as well as other state-of-the-art methods, in mitigating observables produced from random quantum circuits and the Quantum Alternating Operator Ansatz (QAOA) applied to Max-Cut problems with various numbers of qubits, circuit depths and total numbers of shots. We find that the performance of different techniques depends strongly on shot budgets, with more powerful methods requiring more shots for optimal performance. For our largest considered shot budget ( 10 10 ), we find that UNITED gives the most accurate mitigation. Hence, our work represents a benchmarking of current error mitigation methods and provides a guide for the regimes when certain methods are most useful.
Abstract The pursuit of practical quantum utility on near-term quantum processors is critically challenged by their inherent noise. Quantum error mitigation (QEM) techniques are leading solutions to improve computation fidelity with relatively low qubit-overhead, while full-scale quantum error correction remains a distant goal. However, QEM techniques incur substantial measurement overheads, especially when applied to families of quantum circuits parameterized by classical inputs. Focusing on zero-noise extrapolation (ZNE), a widely adopted QEM technique, here we devise the surrogate-enabled ZNE (S-ZNE), which leverages classical learning surrogates to perform ZNE entirely on the classical side. Unlike conventional ZNE, whose measurement cost scales linearly with the number of circuits, S-ZNE requires only constant measurement overhead for an entire family of quantum circuits, offering superior scalability. Theoretical analysis indicates that S-ZNE achieves accuracy comparable to conventional ZNE in many practical scenarios, and numerical experiments on up to 100-qubit ground-state energy and quantum metrology tasks confirm its effectiveness. Our approach provides a template that can be effectively extended to other quantum error mitigation protocols, opening a promising path toward scalable error mitigation.
Quantum error mitigation (QEM) bridges the gap between today's noisy NISQ hardware and fault-tolerant quantum computing by reducing the effect of hardware errors on expectation value estimates without the qubit overhead of full quantum error correction. This paper proposes the Quantum Error Mitigation Design (QEMD) framework, a systematic evaluation of six QEM techniques across four circuit families on IBM Quantum Eagle and IonQ Forte: Zero-Noise Extrapolation (ZNE), Probabilistic Error Cancellation (PEC), Clifford Data Regression (CDR), Symmetry Verification (SV), Dynamical Decoupling (DD), and a novel Adaptive Ensemble Mitigation (AEM) combining ZNE and CDR with context-aware technique selection. QEMD finds: ZNE 3-point Richardson provides the best cost-performance trade-off for QAOA and VQE circuits (4.8x overhead, 28.4pp error reduction); PEC provides the highest accuracy but at 48x shot overhead -- practical only for n <= 12; DD reduces coherence-limited errors by 18.4% on IonQ Forte at zero shot overhead; AEM outperforms all individual techniques by 6.4pp at 8.4x overhead. QEMD provides a decision guide mapping circuit type, qubit count, and shot budget to optimal QEM technique selection.
We investigate a hybrid quantum-classical approach to quantum error mitigation. We propose Classically Augmented Zero-Noise Extrapolation, a hybrid error-mitigation method in which high-noise Richardson extrapolation nodes are replaced by classically simulated estimates. These classical nodes have negligible sampling variance but introduce deterministic simulation bias. We derive the resulting variance reduction under optimal shot allocation and show that, for linear node spacings and fixed index cutoff, the coefficient-level reduction can be exponential. We validate the prediction numerically using Pauli-propagation simulations and demonstrate a reduction in mean-squared error when the truncation bias is sufficiently small.