Challenges
Datasets
Workspaces
Papers
Discussions
Leaderboard
Log inSign up
Challenges
Datasets
Workspaces
Papers
Discussions
Leaderboard
Blog
Job Board
Q3AS

© 2026 Aqora Quantum S.A.S.

TermsPrivacyLegal Notice

arXiv:2007.08653

Dementia Prediction Applying Variational Quantum Classifier

Daniel Sierra-Sosa, Juan D. Arcila-Moreno, Begonya García-Zapirain, Cristián Castillo-Olea, Adel Said Elmaghraby

Published Jul 14, 2020• 19 citations
arXivHTMLPDF

Abstract

Dementia is the fifth cause of death worldwide with 10 million new cases every year. Healthcare applications using machine learning techniques have almost reached the physical limits while more data is becoming available resulting from the increasing rate of diagnosis. Recent research in Quantum Machine Learning (QML) techniques have found different approaches that may be useful to accelerate the training process of existing machine learning models and provide an alternative to learn more complex patterns. This work aims to report a real-world application of a Quantum Machine Learning Algorithm, in particular, we found that using the implemented version for Variational Quantum Classiffication (VQC) in IBM's framework Qiskit allows predicting dementia in elderly patients, this approach proves to provide more consistent results when compared with a classical Support Vector Machine (SVM) with a linear kernel using different number of features.

DOI
10.48550/arxiv.2007.08653

Related papers

Design and Implement a Variational Quantum Classifier for Heart Disease Prediction

Vijayalaxmi Jeure, Veena K

Heart disease is one of the major global causes of death, requiring early and precise detection for efficient treatment.With advancements in quantum computing, Variational Quantum Circuits (VQCs) have gained recognition as a valuable technique for improving learning models in medical diagnosis.This study further explores the application of VQC-based models for heart disease prediction, leveraging quantum computing to enhance classification accuracy.A hybrid quantum-classical model has been developed, which combines classical preprocessing for feature extraction from patient datasets with a VQC-based classifier for medical predictions.The quantum circuit using variational parameters is optimized to reduce the loss function and facilitate effective learning from complex medical data.This proposed approach is tested on benchmark heart disease datasets and evaluated against classical Machine Learning (ML) models, including Support Vector Machines (SVMs), Random Forests, and Neural Networks.The experimental results show that VQC-based models achieve high accuracy and outperform classical models, notably on high-dimensional, non-linearly separable data.The quantum advantage of VQCs lies in their ability to encode and process data in a huge Hilbert space.However, challenges such as noise in near-term quantum devices and scalability issues remain key.This research underscores the efficacy of VQCbased quantum machine learning in medical diagnosis, paving the way for future studies on quantum-enhanced healthcare solutions.Further advancements in quantum hardware and hybrid learning techniques could allow quantum-assisted heart disease prediction to become an effective clinical tool.

International Journal of Drug Delivery Technology•Jul 11, 2026•0 citations

A Comparative Study of Classical and Variational Quantum Machine Learning Models for Breast Cancer Classification

Divya Guthi

Early and accurate diagnosis of breast cancer plays a critical role in improving patient survival rates and reducing treatment costs. Classical machine learning algorithms such as Logistic Regression and Support Vector Machines (SVM) have demonstrated strong performance in medical diagnosis tasks; however, their scalability and representational limits motivate the exploration of emerging paradigms. Quantum Machine Learning (QML), particularly Variational Quantum Classifiers (VQC), has recently gained attention due to its potential to model complex decision boundaries using quantum circuits. This paper presents a comparative analysis between a Variational Quantum Classifier and classical machine learning models for binary breast cancer classification. The study employs dimensionality-reduced clinical data and evaluates model performance using accuracy, confusion matrices, decision boundary visualization, Principal Component Analysis (PCA), and Receiver Operating Characteristic (ROC) curves. Experimental results indicate that the VQC achieves competitive performance with classical approaches, demonstrating its feasibility for small-scale medical datasets and highlighting the promise of quantum-enhanced learning in healthcare applications.

International Journal of Science and Research (IJSR)•Dec 16, 2025•0 citations

Quantum Machine Learning: A Comparative Study of Variational Quantum Classifier with Classical Classifier Algorithms

Madona Alhalabi, Hafiz M. Asif, Hesham Alhalabi

With the advancement of quantum computing in the Noisy Intermediate-Scale Quantum (NISQ) era, hybrid quantum-classical algorithms have emerged as promising approaches for addressing certain machine learning tasks. This study investigates the Variational Quantum Classifier (VQC), a hybrid model that integrates parameterized quantum circuits with classical optimization routines, implemented via IBM’s Qiskit framework. We provide a detailed account of the VQC architecture, including feature encoding, ansatz construction, and optimization methodology. To assess its performance, we conduct a comparative analysis between VQC and classical Support Vector Classifiers (SVC) across synthetic and real-world datasets, including Iris and a binary-filtered version of MNIST. Experimental results reveal that classical models consistently achieve higher accuracy and faster training times. However, the VQC demonstrates functional viability, particularly under noise-free conditions and reduced-dimensionality settings. These findings underscore the current limitations of quantum models while highlighting the potential of VQC as a proof-of-concept for quantum-enhanced learning as quantum hardware matures.

International Symposium on Networks, Computers and Communications (ISNCC)•Oct 27, 2025•1 citation

Quantum Machine Learning for Diabetes Risk Prediction Using Patient Health Data

Kelwin Kong, Senghab Cheng, Sochary Vanda +3 more

Diabetes remains one of the common chronic diseases around the world and finding a good early prediction from clinical and lifestyle data is very important for timely help. Classical machine learning models such as regression, decision trees and random forests have been used for this purpose but the complicated non‑linear connections among clinical features might need richer ways of representation. Quantum Machine Learning (QML) gives an approach using quantum feature encoding and variational circuits to find patterns that are expensive to express with classical methods. In this study we show a diabetes prediction pipeline that compares baseline models—logistic regression, decision tree and random forest—with two quantum classifiers built in Qiskit: a Quantum Support Vector Classifier (QSVC) and a Variational Quantum Classifier (VQC). Using the Pima Indians Diabetes dataset we test all models on accuracy, precision, recall and F1‑score. The results show that the classical Random Forest classifier reaches the accuracy (0.73) beating both quantum classifiers. The Quantum Support Vector Classifier (QSVC 0.66) and the Variational Quantum Classifier (VQC 0.65) are still competitive. Do not outdo the classical baselines. These results agree with reports that in the present Noisy Intermediate‑Scale Quantum (NISQ) era quantum models usually match rather than surpass well‑tuned classical approaches on standard health‑care data and that a real quantum advantage will need larger data, deeper circuits and testing, on real quantum hardware.

•Sep 7, 2026•0 citations

Comparative Study of Quantum and Classical Machine Learning Models in Binary Classification

Anand Kumar Mishra, Ramanuj Awasthi

A potential path forward is Quantum Machine Learning (QML), which aims to leverage quantum computing in conjunction with classical machine learning to enhance computing efficiency and the expressiveness of models. In this paper, two different quantum classifiers - Variational Quantum Classifier (VQC) and Quantum Kernel Support Vector Machine (QSVM) - are compared with three classical classifiers as baseline classifiers - Logistic Regression, Support Vector Machine (SVM), and a Multi-Layer Perceptron (MLP) - on the Breast Cancer Wisconsin dataset. The quantum circuits were created in the PennyLane framework and simulated on a classical backend. However, in terms of accuracy, classical Logistic Regression performed better with an accuracy of 97.8%, classical SVM and QSVM with an accuracy of 95.6% each, although the Quantum VQC achieved a lower accuracy of 88.9% and had a recall of 100% for the benign class, though it correctly identified only 12 of the 17 malignant cases (a malignant-class recall of approximately 70.6%). The drawback of quantum models is the higher training time; however, since the quantum circuit needs to be classically simulated, the quantum SVM took 23.29 seconds compared to less than 0.01 seconds for the classical linear models. These results indicate that for small structured datasets, classifiers based on quantum computing have not yet surpassed well-tuned classical counterparts. In some respects (e.g., benign-class recall), they perform competitively, though not on malignant-class recall, where the VQC in particular performed worse than the classical baselines, which is worth further investigation on real quantum computers.

quant-pharXiv:2609.23476•Sep 22, 2026•0 citations

Quantum-Enhanced Sleep Disorder Prediction: Leveraging VQC and QSVM for Improved Diagnosis

Nikhil K Rohidekar, Geetha J, Sowmya B J

The increasing prevalences of sleep disorders such as insomnia and sleep apnea has become most significant global health concern. Conventional machine learning (ML) models often struggle to deliver very high predictive accuracy or to capture complex and non-linear relationships embedded within multifactorial sleep and lifestyle datasets. This study explores a novel solution by applying the Quantum Machine Learning techniques, specifically the Quantum Support Vector Machine (QSVM) and the Variational Quantum Classifier (VQC), to the Sleep Health and Lifestyle Dataset. The dataset incorporates variables such as sleep duration, physical activity level, stress level, and cardiovascular metrics. Results reveal a clear quantum advantage, with overall accuracy improved by +0.0827 (an 8.27% increase), as the QSVM achieved 0.8100 compared to the traditional classical SVM’s 0.7273. Notably, the QSVM demonstrated superior performance in classifying ambiguous cases, raising the F1-score for the "None" class by 15.4%. These findings highlight Quantum Machine Learning as a robust, data driven avenues for enhancing early diagnosis and personalised intervention strategie.

International Conference on Next-Gen Quantum and Advanced Computing: Algorithms, Security, and Beyond (NQComp)•Mar 5, 2026•0 citations
Dementia is the fifth cause of death worldwide with 10 million new cases every year. Healthcare applications using machine learning techniques have almost reached the physical limits while more data is becoming available resulting from the increasing rate of diagnosis. Recent research in Quantum Machine Learning (QML) techniques have found different approaches that may be useful to accelerate the training process of existing machine learning models and provide an alternative to learn more complex patterns. This work aims to report a real-world application of a Quantum Machine Learning Algorithm, in particular, we found that using the implemented version for Variational Quantum Classiffication (VQC) in IBM's framework Qiskit allows predicting dementia in elderly patients, this approach proves to provide more consistent results when compared with a classical Support Vector Machine (SVM) with a linear kernel using different number of features.
Heart disease is one of the major global causes of death, requiring early and precise detection for efficient treatment.With advancements in quantum computing, Variational Quantum Circuits (VQCs) have gained recognition as a valuable technique for improving learning models in medical diagnosis.This study further explores the application of VQC-based models for heart disease prediction, leveraging quantum computing to enhance classification accuracy.A hybrid quantum-classical model has been developed, which combines classical preprocessing for feature extraction from patient datasets with a VQC-based classifier for medical predictions.The quantum circuit using variational parameters is optimized to reduce the loss function and facilitate effective learning from complex medical data.This proposed approach is tested on benchmark heart disease datasets and evaluated against classical Machine Learning (ML) models, including Support Vector Machines (SVMs), Random Forests, and Neural Networks.The experimental results show that VQC-based models achieve high accuracy and outperform classical models, notably on high-dimensional, non-linearly separable data.The quantum advantage of VQCs lies in their ability to encode and process data in a huge Hilbert space.However, challenges such as noise in near-term quantum devices and scalability issues remain key.This research underscores the efficacy of VQCbased quantum machine learning in medical diagnosis, paving the way for future studies on quantum-enhanced healthcare solutions.Further advancements in quantum hardware and hybrid learning techniques could allow quantum-assisted heart disease prediction to become an effective clinical tool.
Early and accurate diagnosis of breast cancer plays a critical role in improving patient survival rates and reducing treatment costs. Classical machine learning algorithms such as Logistic Regression and Support Vector Machines (SVM) have demonstrated strong performance in medical diagnosis tasks; however, their scalability and representational limits motivate the exploration of emerging paradigms. Quantum Machine Learning (QML), particularly Variational Quantum Classifiers (VQC), has recently gained attention due to its potential to model complex decision boundaries using quantum circuits. This paper presents a comparative analysis between a Variational Quantum Classifier and classical machine learning models for binary breast cancer classification. The study employs dimensionality-reduced clinical data and evaluates model performance using accuracy, confusion matrices, decision boundary visualization, Principal Component Analysis (PCA), and Receiver Operating Characteristic (ROC) curves. Experimental results indicate that the VQC achieves competitive performance with classical approaches, demonstrating its feasibility for small-scale medical datasets and highlighting the promise of quantum-enhanced learning in healthcare applications.
With the advancement of quantum computing in the Noisy Intermediate-Scale Quantum (NISQ) era, hybrid quantum-classical algorithms have emerged as promising approaches for addressing certain machine learning tasks. This study investigates the Variational Quantum Classifier (VQC), a hybrid model that integrates parameterized quantum circuits with classical optimization routines, implemented via IBM’s Qiskit framework. We provide a detailed account of the VQC architecture, including feature encoding, ansatz construction, and optimization methodology. To assess its performance, we conduct a comparative analysis between VQC and classical Support Vector Classifiers (SVC) across synthetic and real-world datasets, including Iris and a binary-filtered version of MNIST. Experimental results reveal that classical models consistently achieve higher accuracy and faster training times. However, the VQC demonstrates functional viability, particularly under noise-free conditions and reduced-dimensionality settings. These findings underscore the current limitations of quantum models while highlighting the potential of VQC as a proof-of-concept for quantum-enhanced learning as quantum hardware matures.
Diabetes remains one of the common chronic diseases around the world and finding a good early prediction from clinical and lifestyle data is very important for timely help. Classical machine learning models such as regression, decision trees and random forests have been used for this purpose but the complicated non‑linear connections among clinical features might need richer ways of representation. Quantum Machine Learning (QML) gives an approach using quantum feature encoding and variational circuits to find patterns that are expensive to express with classical methods. In this study we show a diabetes prediction pipeline that compares baseline models—logistic regression, decision tree and random forest—with two quantum classifiers built in Qiskit: a Quantum Support Vector Classifier (QSVC) and a Variational Quantum Classifier (VQC). Using the Pima Indians Diabetes dataset we test all models on accuracy, precision, recall and F1‑score. The results show that the classical Random Forest classifier reaches the accuracy (0.73) beating both quantum classifiers. The Quantum Support Vector Classifier (QSVC 0.66) and the Variational Quantum Classifier (VQC 0.65) are still competitive. Do not outdo the classical baselines. These results agree with reports that in the present Noisy Intermediate‑Scale Quantum (NISQ) era quantum models usually match rather than surpass well‑tuned classical approaches on standard health‑care data and that a real quantum advantage will need larger data, deeper circuits and testing, on real quantum hardware.
A potential path forward is Quantum Machine Learning (QML), which aims to leverage quantum computing in conjunction with classical machine learning to enhance computing efficiency and the expressiveness of models. In this paper, two different quantum classifiers - Variational Quantum Classifier (VQC) and Quantum Kernel Support Vector Machine (QSVM) - are compared with three classical classifiers as baseline classifiers - Logistic Regression, Support Vector Machine (SVM), and a Multi-Layer Perceptron (MLP) - on the Breast Cancer Wisconsin dataset. The quantum circuits were created in the PennyLane framework and simulated on a classical backend. However, in terms of accuracy, classical Logistic Regression performed better with an accuracy of 97.8%, classical SVM and QSVM with an accuracy of 95.6% each, although the Quantum VQC achieved a lower accuracy of 88.9% and had a recall of 100% for the benign class, though it correctly identified only 12 of the 17 malignant cases (a malignant-class recall of approximately 70.6%). The drawback of quantum models is the higher training time; however, since the quantum circuit needs to be classically simulated, the quantum SVM took 23.29 seconds compared to less than 0.01 seconds for the classical linear models. These results indicate that for small structured datasets, classifiers based on quantum computing have not yet surpassed well-tuned classical counterparts. In some respects (e.g., benign-class recall), they perform competitively, though not on malignant-class recall, where the VQC in particular performed worse than the classical baselines, which is worth further investigation on real quantum computers.
The increasing prevalences of sleep disorders such as insomnia and sleep apnea has become most significant global health concern. Conventional machine learning (ML) models often struggle to deliver very high predictive accuracy or to capture complex and non-linear relationships embedded within multifactorial sleep and lifestyle datasets. This study explores a novel solution by applying the Quantum Machine Learning techniques, specifically the Quantum Support Vector Machine (QSVM) and the Variational Quantum Classifier (VQC), to the Sleep Health and Lifestyle Dataset. The dataset incorporates variables such as sleep duration, physical activity level, stress level, and cardiovascular metrics. Results reveal a clear quantum advantage, with overall accuracy improved by +0.0827 (an 8.27% increase), as the QSVM achieved 0.8100 compared to the traditional classical SVM’s 0.7273. Notably, the QSVM demonstrated superior performance in classifying ambiguous cases, raising the F1-score for the "None" class by 15.4%. These findings highlight Quantum Machine Learning as a robust, data driven avenues for enhancing early diagnosis and personalised intervention strategie.