Transitioning quantum computing from laboratory physical demonstrations to practical, utility-scale processing requires bridging a multi-order-of-magnitude gap between physical gate fidelities and algorithmic error thresholds. While fault-tolerant quantum computing relies on quantum error correction to span this divide, traditional evaluation metrics focused on isolated physical components fail to reflect real-world execution capacity. In this Perspective, we analyze the physical and microarchitectural bottlenecks governing scalable quantum compute engines: the spatial footprint trade-offs between code encoding efficiency and hardware routing, the temporal latencies of closed-loop decoding under strict cryogenic thermal budgets, and the structural performance asymmetries of modular multi-chip networks. We argue that overcoming these multi-faceted scalability barriers demands moving beyond single-layer hardware optimizations toward a holistic full-stack co-design paradigm—jointly tailoring error-correcting code topologies, control microarchitectures, and interconnect networks to unlock sustainable logical throughput.
Transitioning quantum computing from laboratory physical demonstrations to practical, utility-scale processing requires bridging a multi-order-of-magnitude gap between physical gate fidelities and algorithmic error thresholds. While fault-tolerant quantum computing relies on quantum error correction to span this divide, traditional evaluation metrics focused on isolated physical components fail to reflect real-world execution capacity. In this Perspective, we analyze the physical and microarchitectural bottlenecks governing scalable quantum compute engines: the spatial footprint trade-offs between code encoding efficiency and hardware routing, the temporal latencies of closed-loop decoding under strict cryogenic thermal budgets, and the structural performance asymmetries of modular multi-chip networks. We argue that overcoming these multi-faceted scalability barriers demands moving beyond single-layer hardware optimizations toward a holistic full-stack co-design paradigm—jointly tailoring error-correcting code topologies, control microarchitectures, and interconnect networks to unlock sustainable logical throughput.
The promise of fault-tolerant quantum computation rests on its ability to solve certain intractable problems exponentially faster than classical computers. However, this theoretical promise is challenged by a cascade of interconnected physical bottlenecks, where the act of scaling quantum resources to suppress errors creates insurmountable thermal and classical processing loads. This paper develops an integrated thermal equilibrium model that quantitatively links physical gate fidelity, quantum error correction (QEC) overhead, and cryogenic cooling capacity to determine the viability of a large-scale system. Through numerical analysis of a system designed to execute Shor’s algorithm, the model demonstrates that even under optimistic technological assumptions, the required physical resources—in terms of qubit count, cooling power, and classical decoding speed—remain orders of magnitude beyond plausible near-term capabilities. The findings indicate that the primary barrier to scalable quantum computation is not a single engineering challenge but a systemic, multi-physics resource gap, where the polynomial scaling of classical support systems fails to keep pace with the exponential demands of the quantum core. This suggests that progress requires a holistic co-design of algorithms, hardware, and control systems rather than isolated improvements in qubit count alone.
Quantum error correction (QEC) has transitioned from a theoretical promise to an experimental reality, with recent demonstrations of below-threshold logical qubits marking a turning point in the quest for fault-tolerant quantum computing. Over the past five years, breakthroughs in surface code implementations, low-latency decoders, and improved physical qubit fidelities have brought us to the brink of scalable logical qubit systems. Yet the road to practical quantum advantage remains steep: correlated noise, cryogenic control complexity, and the resource overhead of magic state distillation still pose major barriers. Here, we synthesize recent progress across superconductng, trapped-ion, and neutral-atom platforms, assess the state-of the-art in topological and LDPC codes, and highlight engineering challenges that must be overcome to achieve systems with thousands of logical qubits. We argue that the 2025-2035 decade will be decisive for quantum computing, with success hinging on co-design of hardware, software, and algorithms. This perspective outlines a roadmap for the next generation of fault tolerant systems and discusses the societal and economic implications of entering the era of practical quantum advantage.
Scalable quantum computation is expected to rely on fault-tolerant quantum computation (FTQC), in which quantum error correction (QEC) suppresses physical errors sufficiently to support reliable logical operations. This requires quantum compilation to move beyond general-purpose circuit optimization toward encoding-aware and protocol-structured compilation across the full stack of fault-tolerant quantum computers. Beyond circuit synthesis and hardware mapping, an FTQC compiler must lower algorithm-level operations into the logical gate set supported by the chosen code, coordinate encoded data and ancilla resources, realize logical operations together with repeated syndrome extraction under hardware constraints, and provide the resulting measurement stream to real-time decoding.
This survey presents a full-stack view of compiler design for QEC-protected quantum computation. We organize existing work into three interacting layers: logical-level QEC compilation, physical-level QEC realization, and decoder runtime integration. At the logical level, we review surface-code lattice-surgery compilers, beyond-surface-code code-surgery frameworks including emerging qLDPC approaches, and compilation support for non-Clifford operations such as magic-state distillation and code switching. At the physical level, we survey hardware-aware QEC realization on superconducting, trapped-ion, and neutral-atom platforms. We further examine decoder models, real-time decoding systems, and frame-management mechanisms that close the feedback loop during fault-tolerant execution. Finally, we identify open challenges in cross-layer optimization, qLDPC compilation, compiler-decoder co-design, runtime adaptivity, and the development of integrated and benchmarkable FTQC compilation stacks. An actively maintained paper list is available at: github.com/chenghongz/QEC-compiler-design.
The transition from noisy intermediate-scale quantum (NISQ) processors to large-scale fault-tolerant machines requires more than incremental improvements in physical qubit fidelity. While advances in quantum error correction (QEC) theory continue to lower the theoretical overhead of quantum computing, much of this research remains abstracted from the physical realities of qubit implementations. This disconnect often results in hardware-agnostic designs that are inefficient or impractical to build. In this dissertation, I identify three primary gaps between theoretical QEC research and practical hardware: (1) the high levels of noise and temporal instability in experimental devices that impede scalable QEC; (2) the prohibitively large qubit and time costs of useful algorithms, driven largely by the limitations of the standard surface code; and (3) the failure of current resource estimates to account for hardware-level constraints, such as limited connectivity and the complexity of implementing non-local operations. To bridge these gaps, I propose a holistic, cross-stack approach where the error correction protocols and the physical hardware are designed in concert. By developing realistic device models and hardware-aware solutions at the lowest levels of the software stack, we can accelerate the path toward functional fault-tolerance. I present my work across three research thrusts: first, leveraging codesign to mitigate hardware-specific noise and reduce physical error rates; second, developing software tools for fault-tolerant quantum computers to reduce the space-time overhead of the QEC layer; and third, proposing two novel hardware-aware QEC architectures that provide practical, high-performance routes to scalable quantum computation.
Quantum error correction (QEC) represents the cornerstone technology for realizing fault-tolerant quantum computing, addressing the fundamental challenge of quantum state decoherence in noisy intermediate-scale quantum (NISQ) devices. This comprehensive review examines recent advances in QEC implementations from 2020-2024, spanning theoretical foundations to practical hardware demonstrations. We analyze the evolution from pioneering stabilizer codes to modern topological approaches, with particular emphasis on surface codes and low-density parity-check (LDPC) codes that have demonstrated below-threshold error correction in superconducting and trapped-ion systems. The paper provides a comparative analysis of classical and machine learning-based decoder algorithms, evaluating their performance through complexity analysis and threshold comparisons in real-time error correction scenarios. Through examination of breakthrough experiments by Google, IBM, Quantinuum, and emerging platforms, we assess the current state of fault-tolerant quantum computing and identify critical engineering challenges including correlated noise models, cryogenic control systems, and scalable logical gate implementations. Our quantitative analysis reveals that while significant progress has been made toward practical fault-tolerance thresholds, achieving the resource efficiency and reliability required for large-scale quantum computation remains challenging. We provide detailed resource estimates for key applications including Shor's algorithm and optimization problems, along with analysis of industry roadmaps toward thousand-logical-qubit systems. This review serves as a comprehensive guide for researchers and engineers working toward the next generation of fault-tolerant quantum computers, with particular focus on information-theoretic perspectives relevant to quantum information entropy and syndrome processing.
Quantum computing is transitioning from laboratory research to industrial deployment, yet significant challenges persist: system scalability and performance, fabrication yields, and the advancement of algorithms and applications. We emphasize that in building quantum computers -- spanning quantum chips, system integration, instruction sets, algorithms, and middleware such as quantum error correction schemes -- design is everywhere. In this paper, we advocate for a holistic design perspective in quantum computing, a perspective we argue is pivotal to unlocking innovative co-design opportunities and addressing the aforementioned key challenges. To equip readers with sufficient background for exploring co-optimization opportunities, we detail how interconnected computational methods and tools collaborate to enable end-to-end quantum computer design. This coverage encompasses critical stages -- such as chip layout design automation, high-fidelity system-level simulation, Hamiltonian derivation for quantum system modeling, control pulse simulation, decoherence analysis, and physical verification and testing -- followed by quantum instruction set design. We then proceed to quantum system and software development, including quantum circuit synthesis, quantum error correction and fault tolerance, and logic verification and testing. Through these discussions, we illustrate with concrete examples -- including co-optimizing quantum instruction sets with algorithmic considerations, customizing error correction circuits to hardware-specific constraints, and streamlining quantum chip design through tailored code design, among others. We hope that the detailed end-to-end design workflow as well as these examples will foster dialogue between the hardware and software communities, ultimately facilitating the translation of meaningful research findings into future quantum hardware implementations.