Quantum computing promises computational speedups over classical approaches for certain problem classes; however, in near term quantum and classical hybrid workflows, the overall performance is often constrained by classical processing overhead. The time cost associated with circuit compilation, which includes gate decomposition, topology aware qubit mapping, and depth optimization, together with protocol level communication such as circuit transfer and measurement result exchange, frequently exceeds the actual quantum circuit execution time and has become a critical bottleneck to practical deployment. In this paper, we propose QPanda 3.0, a high performance quantum programming framework optimized to accelerate the classical compilation path that underpins NISQ era hybrid integration. Leveraging an optimized compilation pipeline, a custom binary instruction stream (OriginBIS), and hardware aware execution strategies, QPanda 3.0 achieves up to 86.9 × faster encoding and 35.6 × faster decoding than OpenQASM 2.0, as well as an average 10.7 × compilation speedup over Qiskit across the four evaluated connectivity topologies, with a peak speedup of 597 × for a 118-qubit W-state circuit on a square topology. These capabilities enable the development of scalable quantum algorithms across various domains, including finance, materials science, and combinatorial optimization, supporting both industrial deployment and cloud based execution in hybrid computing environments.
Quantum computing promises computational speedups over classical approaches for certain problem classes; however, in near term quantum and classical hybrid workflows, the overall performance is often constrained by classical processing overhead. The time cost associated with circuit compilation, which includes gate decomposition, topology aware qubit mapping, and depth optimization, together with protocol level communication such as circuit transfer and measurement result exchange, frequently exceeds the actual quantum circuit execution time and has become a critical bottleneck to practical deployment. In this paper, we propose QPanda 3.0, a high performance quantum programming framework optimized to accelerate the classical compilation path that underpins NISQ era hybrid integration. Leveraging an optimized compilation pipeline, a custom binary instruction stream (OriginBIS), and hardware aware execution strategies, QPanda 3.0 achieves up to 86.9 × faster encoding and 35.6 × faster decoding than OpenQASM 2.0, as well as an average 10.7 × compilation speedup over Qiskit across the four evaluated connectivity topologies, with a peak speedup of 597 × for a 118-qubit W-state circuit on a square topology. These capabilities enable the development of scalable quantum algorithms across various domains, including finance, materials science, and combinatorial optimization, supporting both industrial deployment and cloud based execution in hybrid computing environments.
In emerging quantum-classical integration applications, the classical time cost-especially from compilation and protocol-level communication often exceeds the execution time of quantum circuits themselves, posing a severe bottleneck to practical deployment. To overcome these limitations, QPanda3 has been extensively optimized as a high-performance quantum programming framework tailored for the demands of the NISQ era and quantum-classical hybrid workflows. It features optimized circuit compilation, a custom binary instruction stream (OriginBIS), and hardware-aware execution strategies to significantly reduce latency and communication overhead. OriginBIS achieves up to 86.9× faster encoding and 35.6× faster decoding than OpenQASM 2.0, addressing critical bottlenecks in hybrid quantum systems. Benchmarks show 10.7× compilation speedup and up to 597× acceleration in compiling large-scale circuits (e.g., a 118-qubit W-state) compared to Qiskit. n high-performance simulation, QPanda3 excels in variational quantum algorithms, achieving up to 26× faster gradient computation than Qiskit, with minimal time-complexity growth across circuit depths. These capabilities make QPanda3 well-suited for scalable quantum algorithm development in finance, materials science, and combinatorial optimization, while supporting industrial deployment and cloud-based execution in quantum-classical hybrid computing scenarios.
To address the urgent need in the NISQ era for high-performance, scalable quantum compilers and to advance the integration of classical and quantum computing, we present QLLVM, an advanced Quantum-Classical co-compilation framework built on LLVM. To our knowledge, QLLVM delivers an end-to-end, LLVM-based compilation workflow that unifies the build of classical high-performance programs, including CUDA, MPI, and C++, together with quantum programs into a single executable. For quantum program compilation, QLLVM adopts a three-stage design: high-level optimizations are implemented in the MLIR Quantum dialect and then lowered to QIR, an LLVM IR-based representation, for low-level optimization and hardware mapping. Its extensible architecture and seamless interoperability with classical high-performance computing provide an efficient, flexible, industrial-grade compilation infrastructure for future quantum software development. Experimental results show that, on the MQTBench benchmark suite, QLLVM reduces circuit depth and gate counts compared with state-of-the-art compilers and demonstrates clear advantages in compiling hybrid classical-quantum programs.
The recent times of fast development of quantum computers has been followed by many researchers who want to run the larger and more difficult quantum algorithms on it and they have promised such speedup several times. Notwithstanding this, commercial quantum computers are currently fraught with instability and errors. This paper is centered on development of the customized compiler for quantum computing with aid of Qiskit Terra, a QIS framework. We target central classes such as circuit representation structures, programming techniques based on OpenQASM, challenges in the QC architecture, high-level routing optimization, and the structure of the Qiskit Terra compiler. In every circuit, the optimization is provided by methods of Qiskit Terra, including Trivial Layout, Noise Adaptive Layout, Dense Layout, and Custom Layout. These optimization levels address many problems that emerge when circuits are being compiled and executed, and thus, the optimization levels seek to boost circuit efficiency, reduce the count of gates, and enhance the overall performance. The introduction of numerous optimization passes starting from unroller passes that translate gates, the layout passes that map virtual to physical qubits, and the optimization algorithm aimed at the runtime reduction. Modern quantum compilation technologies are being currently developed based on economic (and theoretical) analyses to underpin the investigation and development of optimal quantum computation procedures.
Hybridizing machine learning (ML) with quantum computing has become an attractive strategy to increase computational power on Noisy Intermediate Scale Quantum (NISQ) devices. Although these can be potentially quantum advantage devices, their qubit numbers and noise are bounded and there are challenges when it comes to practical quantum circuit realization. This work concentrates on the creation of optimized quantum circuits via ML-based strategies, to enhance the performance of the circuits, to reduce the error rate and to accommodate the particular noise profile of the hardware of NISQ devices. The resulting suboptimal mappings with little or no consideration of noise and hardware topology in traditional quantum compilers can ruin the fidelity of quantum algorithm. Leveraging machine learning, and specifically reinforcement and supervised learning methods, our method learns to optimize compilation strategy for specific quantum hardware architecture. The paper proposes a framework that uses machine learning models to predict qubit mappings, gate decompositions, and transpilation paths that minimize gate depth and error accumulation. We also investigate transfer learning methods for propagating the learned compilation strategies to novel NISQ machines. Such methods are empirically validated on both simulated and real quantum hardware backends, providing evidence of circuit depth, execution time and error reductions. The results show that ML-assisted compilation can achieve better success probabilities for benchmark quantum algorithms like VQE and QAOA than conventional compilers. Furthermore, the work examines the interpretability of ML models providing hardware-aware optimization recommendations and understanding the noise patterns and methods of error correction. Our work highlights the key role of ML for transferring between theoretical quantum algorithms and their practical NISQ implementations. This integration boosts the immediate applicability of existing quantum devices and provides a basis for adaptive and scalable likelihood-based compilation for the era of fault-tolerant quantum computation. Our results motivate further investigation of hybrid classical-quantum workflows, in which ML iteratively improves compilation in accordance with changing hardware noise and capabilities. By improving quantum circuit compilation onNISQ computers, this work is taking steps toward the realization of quantum advantage in application scenarios such as optimization, cryptography, and quantum simulation without needing to wait for fully fault-tolerant large-scale quantum computers.
The rapid evolution of Noisy Intermediate-Scale Quantum (NISQ) devices has intensified the need for robust compilation strategies capable of mitigating hardware-induced errors while maximizing computational efficiency. Quantum compilers play a pivotal role in translating high-level quantum algorithms into hardware-executable instructions, yet they face significant challenges related to qubit connectivity constraints, limited coherence times, and stochastic noise. This paper examines error-resilient quantum compiler design for efficient qubit mapping, gate optimization, and noise mitigation in NISQ-era devices, proposing a framework that integrates topology-aware mapping, adaptive gate synthesis, and probabilistic error suppression techniques. By synthesizing advances in quantum circuit optimization, hardware-aware scheduling, and hybrid classical–quantum error correction strategies, the study evaluates how compiler-level innovations can substantially enhance execution fidelity and resource efficiency. The findings suggest that intelligent compiler architectures are critical enablers of practical quantum advantage during the transitional NISQ phase, bridging theoretical algorithm design with real-world hardware constraints.
Quantum computing, leveraging the principles of superposition and entanglement, holds the potential to revolutionize computational problem-solving across a wide array of fields, from cryptography to complex system simulations. However, unlocking the full power of quantum computing requires the development of advanced quantum compilation techniques that can efficiently map high-level algorithms onto physical quantum hardware. This paper delves into state-of-the-art optimization strategies within quantum compilers, with a particular focus on methods such as Relaxed Peephole Optimization (RPO), gate reordering techniques for the Quantum Approximate Optimization Algorithm (QAOA), and reinforcement learning (RL)-driven frameworks. It also explores innovative approaches like distributed quantum compilation, parity quantum optimization, and the Paulihedral framework, all designed to minimize gate counts, reduce circuit depth, and optimize overall resource utilization. A key contribution of this work is the introduction of error mitigation techniques that enhance the fidelity and scalability of quantum circuits, particularly on noisy intermediate-scale quantum (NISQ) devices. Through comprehensive empirical evaluations across a variety of quantum algorithms, the paper demonstrates significant improvements in critical performance metrics such as circuit depth, gate count, and execution efficiency, providing a promising direction for optimizing quantum circuit design tailored to diverse quantum hardware platforms.