Challenges
Datasets
Workspaces
Papers
Discussions
Leaderboard
Log inSign up
Challenges
Datasets
Workspaces
Papers
Discussions
Leaderboard
Blog
Job Board
Q3AS

© 2026 Aqora Quantum S.A.S.

TermsPrivacyLegal Notice

International Conference on Engineering, Technologies and Systems (TechSys)

Quantum Machine Learning for Enhanced Cardiovascular Disease Risk Prediction

Vеskа Gаnchеvа, Valentin Tsvetkov

Published Jul 21, 2026• 0 citations
Publisher

Abstract

Quantum computing has emerged as a powerful tool for solving complex problems in various fields. Personalized medicine, tailoring medical treatment to patients based on their genetic and health data, is one area where predictive analytics can be useful. This work explores the application of quantum algorithms for predictive analytics, specifically in the context of predicting outcomes of cardiovascular disease based on patient data. This research is focused on the quantum-based predictive models for the case study of cardiovascular disease. The models are based on Quantum Support Vector Machines, Quantum Neural Networks, and Variational Quantum Eigensolver algorithms. The software implementation is based on the Python programming language, including an integrated quantum algorithm. A dataset of cardiovascular disease from an online platform is used to train and evaluate the models.

DOI
10.3390/engproc2026150039

Related papers

Comparative Analysis on Cardiovascular Disease Prediction using Quantum Machine Learning

S. Venkata Ramana, K. N. Hanumantha Rao, L. Hima Teja +1 more

Cardiovascular disease is one of the most common reasons of increases the global death rate, suggesting initial detection and timely treatment crucial. While traditional machine learning models have been effective in predicting heart disease, Quantum Computing (QC) introduces new possibilities for improving accuracy and processing speed. In this regard the application of Quantum Machine Learning (QML) approaches-categorically, Quantum Neural Networks (QNN) and Quantum Support Vector Classification (QSVC)-to predict heart disease using key health indicators such as present-age, levels of cholesterol, Blood Pressure (BP), and lifestyle choices. QNN is utilized to recognize complex patterns in patient data, leveraging deep learning to understand intricate connections between various risk factors. Meanwhile, QSVC takes advantage of QC ability to compute large amounts of information at once, making classification faster and more precise. Both models are trained and tested on a heart disease dataset and compared with traditional machine learning methods to assess their accuracy, efficiency, and scalability. The results show that while quantum and classical models achieve similar accuracy, quantum computing significantly reduces processing time, making it highly efficient for analyzing large datasets. This study highlights the strength of QC in transforming medical diagnostics, offering faster and more reliable predictive models for early heart disease detection. By integrating quantum algorithms into healthcare, this research contributes to the advancement of AI-driven medical solutions, resulting in more efficient and individual patient care.

IEEE Wireless Antenna and Microwave Symposium (WAMS)•Jun 5, 2025•1 citation

A Comparative Review of Quantum Neural Networks and Classical Machine Learning for Cardiovascular Disease Risk Prediction

Nouf Ali AL Ajmi, Muhammad Shoaib

Cardiac risk prediction is critical for the early detection and prevention of cardiovascular diseases, a leading global cause of mortality. In response to the growing volume and complexity of healthcare data, there has been increasing reliance on computational approaches to enhance clinical decision-making and improve early detection of cardiac risks. Although classical machine learning techniques have demonstrated strong performance in cardiovascular disease prediction, their efficiency and scalability are increasingly challenged by high-dimensional and large-scale medical datasets. Emerging advances in quantum computing have introduced quantum machine learning (QML) as a promising alternative, offering novel computational paradigms with the potential to outperform classical methods in terms of speed and problem-solving capability. This review analyzed twelve studies, evaluating data types, quantum architecture, performance metrics, and comparative efficacy against classical machine learning models. Our findings indicate that QNNs show promise for enhanced predictive accuracy and computational efficiency. However, significant challenges in scalability, noise resilience, and clinical integration persist. The translation of quantum advantage into clinical practice necessitates further validation on large-scale with diverse datasets.

Computers•Feb 2, 2026•2 citations

Quantum-Enhanced Multi-Modal Cardiac Biomarker Analysis for Cardiovascular Disease Risk Prediction

Pathan, Shadman Mahmood Khan, Imran, Sakan Binte, Vahala, Linda

Cardiovascular disease (CVD) remains a major global health challenge, necessitating advanced predictive models for early detection and risk assessment. This paper presents a quantum-enhanced machine learning framework for multi-modal cardiac biomarker analysis. The model integrates quantum feature encoding with a deep learning-based classification pipeline. Multi-modal data from imaging, electrophysiological signals, and genetic biomarkers are mapped into quantum-enhanced feature spaces using Cirq. These transformed features are then fed into a hybrid quantum-classical neural network (QNN) to improve prediction accuracy. The proposed approach is benchmarked against classical machine learning methods such as Support Vector Machines (SVM) and Random Forest (RF). Results show the potential of quantum computing in advancing precision medicine by leveraging high-dimensional feature transformations.

•Apr 22, 2025•0 citations

A Comparative Study of Classical and Quantum Algorithms for Heart Disease Prediction Using Patients' Vital Signs

Paramita Basak Upama, Parama Sridevi, Masud Rabbani +5 more

The aim of this study is to enhance the accuracy and reduce the time complexity of predicting cardiac illnesses by utilizing patient vital signs exclusively. The importance of timely treatment in critical situations where quick decisions are necessary is emphasized here. Precise predictions have the potential to prevent health deterioration and even save lives. By analyzing vast datasets (images, texts etc.) and detecting subtle patterns, quantum machine learning algorithms (QML) can offer more accurate results in a shorter period compared to classical algorithms. The feature set used here is a novel one to be used for the quick detection and early prediction of cardiovascular diseases, and also a convenient one for this task. To predict heart diseases or abnormalities, both classical and quantum machine learning techniques have been employed in this paper. We have developed four models based on Support Vector Machine (SVM), Neural Network (NN), Quantum Support Vector Machine (QSVM), and Quantum Neural Network (QNN) and compared their performance on a balanced sample of a vast dataset for heart diseases prediction. After comparing the models' performance, we found that Quantum Support Vector Machine (QSVM) performed best with an accuracy of 75% and to-fold Cross-validation score of 80%.

IEEE Annual International Computer Software and Applications Conference (COMPSAC)•Jul 2, 2024•2 citations

Design and Implement a Variational Quantum Classifier for Heart Disease Prediction

Vijayalaxmi Jeure, Veena K

Heart disease is one of the major global causes of death, requiring early and precise detection for efficient treatment.With advancements in quantum computing, Variational Quantum Circuits (VQCs) have gained recognition as a valuable technique for improving learning models in medical diagnosis.This study further explores the application of VQC-based models for heart disease prediction, leveraging quantum computing to enhance classification accuracy.A hybrid quantum-classical model has been developed, which combines classical preprocessing for feature extraction from patient datasets with a VQC-based classifier for medical predictions.The quantum circuit using variational parameters is optimized to reduce the loss function and facilitate effective learning from complex medical data.This proposed approach is tested on benchmark heart disease datasets and evaluated against classical Machine Learning (ML) models, including Support Vector Machines (SVMs), Random Forests, and Neural Networks.The experimental results show that VQC-based models achieve high accuracy and outperform classical models, notably on high-dimensional, non-linearly separable data.The quantum advantage of VQCs lies in their ability to encode and process data in a huge Hilbert space.However, challenges such as noise in near-term quantum devices and scalability issues remain key.This research underscores the efficacy of VQCbased quantum machine learning in medical diagnosis, paving the way for future studies on quantum-enhanced healthcare solutions.Further advancements in quantum hardware and hybrid learning techniques could allow quantum-assisted heart disease prediction to become an effective clinical tool.

International Journal of Drug Delivery Technology•Jul 11, 2026•0 citations

HEART DISEASE RISK PREDICITION USING QUANTUM MACHINE LEARNING

RACHAKONDA KOUSHIK SAGAR, S VARA PRASAD, ANABATHULA RUCHITA +2 more

Cardiovascular disease remains one of the leading causes of death worldwide, making early and accurate risk prediction essential. Conventional machine learning models often struggle to handle complex medical data, resulting in limited accuracy and reduced interpretability. To address these challenges, this study presents a hybrid prediction framework that combines Quantum Machine Learning (QML) with ensemble learning techniques. Classical models such as Support Vector Classifier (SVC) and Artificial Neural Network (ANN) are used as baseline approaches. In addition, quantum models including QSVC, Variational Quantum Classifier (VQC), and Quantum Neural Network (QNN) are employed to capture complex non-linear patterns present in clinical data. To further enhance performance, a Bagging-QSVC ensemble model is proposed, improving robustness and overall classification accuracy. Interpretability is incorporated using SHAP, allowing the model’s predictions to be more transparent and easier to understand in a clinical context. Experimental results indicate that the proposed quantum ensemble achieves an accuracy of around 90%, outperforming both classical models and individual quantum models. Furthermore, a real-time user interface is developed, enabling clinicians to input patient data and receive immediate risk predictions. Overall, the system provides a reliable and interpretable solution suitable for practical clinical decision support.

Technix International Journal for Engineering Research•Jan 1, 2026•0 citations
Quantum computing has emerged as a powerful tool for solving complex problems in various fields. Personalized medicine, tailoring medical treatment to patients based on their genetic and health data, is one area where predictive analytics can be useful. This work explores the application of quantum algorithms for predictive analytics, specifically in the context of predicting outcomes of cardiovascular disease based on patient data. This research is focused on the quantum-based predictive models for the case study of cardiovascular disease. The models are based on Quantum Support Vector Machines, Quantum Neural Networks, and Variational Quantum Eigensolver algorithms. The software implementation is based on the Python programming language, including an integrated quantum algorithm. A dataset of cardiovascular disease from an online platform is used to train and evaluate the models.
Cardiovascular disease is one of the most common reasons of increases the global death rate, suggesting initial detection and timely treatment crucial. While traditional machine learning models have been effective in predicting heart disease, Quantum Computing (QC) introduces new possibilities for improving accuracy and processing speed. In this regard the application of Quantum Machine Learning (QML) approaches-categorically, Quantum Neural Networks (QNN) and Quantum Support Vector Classification (QSVC)-to predict heart disease using key health indicators such as present-age, levels of cholesterol, Blood Pressure (BP), and lifestyle choices. QNN is utilized to recognize complex patterns in patient data, leveraging deep learning to understand intricate connections between various risk factors. Meanwhile, QSVC takes advantage of QC ability to compute large amounts of information at once, making classification faster and more precise. Both models are trained and tested on a heart disease dataset and compared with traditional machine learning methods to assess their accuracy, efficiency, and scalability. The results show that while quantum and classical models achieve similar accuracy, quantum computing significantly reduces processing time, making it highly efficient for analyzing large datasets. This study highlights the strength of QC in transforming medical diagnostics, offering faster and more reliable predictive models for early heart disease detection. By integrating quantum algorithms into healthcare, this research contributes to the advancement of AI-driven medical solutions, resulting in more efficient and individual patient care.
Cardiac risk prediction is critical for the early detection and prevention of cardiovascular diseases, a leading global cause of mortality. In response to the growing volume and complexity of healthcare data, there has been increasing reliance on computational approaches to enhance clinical decision-making and improve early detection of cardiac risks. Although classical machine learning techniques have demonstrated strong performance in cardiovascular disease prediction, their efficiency and scalability are increasingly challenged by high-dimensional and large-scale medical datasets. Emerging advances in quantum computing have introduced quantum machine learning (QML) as a promising alternative, offering novel computational paradigms with the potential to outperform classical methods in terms of speed and problem-solving capability. This review analyzed twelve studies, evaluating data types, quantum architecture, performance metrics, and comparative efficacy against classical machine learning models. Our findings indicate that QNNs show promise for enhanced predictive accuracy and computational efficiency. However, significant challenges in scalability, noise resilience, and clinical integration persist. The translation of quantum advantage into clinical practice necessitates further validation on large-scale with diverse datasets.
Cardiovascular disease (CVD) remains a major global health challenge, necessitating advanced predictive models for early detection and risk assessment. This paper presents a quantum-enhanced machine learning framework for multi-modal cardiac biomarker analysis. The model integrates quantum feature encoding with a deep learning-based classification pipeline. Multi-modal data from imaging, electrophysiological signals, and genetic biomarkers are mapped into quantum-enhanced feature spaces using Cirq. These transformed features are then fed into a hybrid quantum-classical neural network (QNN) to improve prediction accuracy. The proposed approach is benchmarked against classical machine learning methods such as Support Vector Machines (SVM) and Random Forest (RF). Results show the potential of quantum computing in advancing precision medicine by leveraging high-dimensional feature transformations.
The aim of this study is to enhance the accuracy and reduce the time complexity of predicting cardiac illnesses by utilizing patient vital signs exclusively. The importance of timely treatment in critical situations where quick decisions are necessary is emphasized here. Precise predictions have the potential to prevent health deterioration and even save lives. By analyzing vast datasets (images, texts etc.) and detecting subtle patterns, quantum machine learning algorithms (QML) can offer more accurate results in a shorter period compared to classical algorithms. The feature set used here is a novel one to be used for the quick detection and early prediction of cardiovascular diseases, and also a convenient one for this task. To predict heart diseases or abnormalities, both classical and quantum machine learning techniques have been employed in this paper. We have developed four models based on Support Vector Machine (SVM), Neural Network (NN), Quantum Support Vector Machine (QSVM), and Quantum Neural Network (QNN) and compared their performance on a balanced sample of a vast dataset for heart diseases prediction. After comparing the models' performance, we found that Quantum Support Vector Machine (QSVM) performed best with an accuracy of 75% and to-fold Cross-validation score of 80%.
Heart disease is one of the major global causes of death, requiring early and precise detection for efficient treatment.With advancements in quantum computing, Variational Quantum Circuits (VQCs) have gained recognition as a valuable technique for improving learning models in medical diagnosis.This study further explores the application of VQC-based models for heart disease prediction, leveraging quantum computing to enhance classification accuracy.A hybrid quantum-classical model has been developed, which combines classical preprocessing for feature extraction from patient datasets with a VQC-based classifier for medical predictions.The quantum circuit using variational parameters is optimized to reduce the loss function and facilitate effective learning from complex medical data.This proposed approach is tested on benchmark heart disease datasets and evaluated against classical Machine Learning (ML) models, including Support Vector Machines (SVMs), Random Forests, and Neural Networks.The experimental results show that VQC-based models achieve high accuracy and outperform classical models, notably on high-dimensional, non-linearly separable data.The quantum advantage of VQCs lies in their ability to encode and process data in a huge Hilbert space.However, challenges such as noise in near-term quantum devices and scalability issues remain key.This research underscores the efficacy of VQCbased quantum machine learning in medical diagnosis, paving the way for future studies on quantum-enhanced healthcare solutions.Further advancements in quantum hardware and hybrid learning techniques could allow quantum-assisted heart disease prediction to become an effective clinical tool.
Cardiovascular disease remains one of the leading causes of death worldwide, making early and accurate risk prediction essential. Conventional machine learning models often struggle to handle complex medical data, resulting in limited accuracy and reduced interpretability. To address these challenges, this study presents a hybrid prediction framework that combines Quantum Machine Learning (QML) with ensemble learning techniques. Classical models such as Support Vector Classifier (SVC) and Artificial Neural Network (ANN) are used as baseline approaches. In addition, quantum models including QSVC, Variational Quantum Classifier (VQC), and Quantum Neural Network (QNN) are employed to capture complex non-linear patterns present in clinical data. To further enhance performance, a Bagging-QSVC ensemble model is proposed, improving robustness and overall classification accuracy. Interpretability is incorporated using SHAP, allowing the model’s predictions to be more transparent and easier to understand in a clinical context. Experimental results indicate that the proposed quantum ensemble achieves an accuracy of around 90%, outperforming both classical models and individual quantum models. Furthermore, a real-time user interface is developed, enabling clinicians to input patient data and receive immediate risk predictions. Overall, the system provides a reliable and interpretable solution suitable for practical clinical decision support.