Challenges
Datasets
Workspaces
Papers
Discussions
Leaderboard
Log inSign up
Challenges
Datasets
Workspaces
Papers
Discussions
Leaderboard
Blog
Job Board
Q3AS

© 2026 Aqora Quantum S.A.S.

TermsPrivacyLegal Notice

Quantum in Neurodegeneration: Investigating A New Mechanism of Protein Damage

Ashish Kumar

Published Jun 30, 2026• 0 citations
Publisher

Abstract

Findings related to quantum mechanics over the last century have had a pivotal role in our understanding of key physical, chemical, and biological features. Using manipulations of Schrödinger’s wavefunction, we describe electron tunneling through orbits. We extend our findings to a biological setting where we theorize an imbalance in exothermic biochemical reactions may contribute to protein damage. Additionally, we posit the cellular environment encourages electron binding among higher principal quantum orbits than traditionally assumed. This model can be one of many explanations for the sporadic nature of neurodegenerative disease where protein damage, misfolding, or aggregation is a key characteristic.

DOI
10.33774/coe-2026-9v4wk

Related papers

Quantum in Neurodegeneration: Investigating A New Mechanism of Protein Damage

Ashish Kumar

Findings related to quantum mechanics over the last century have had a pivotal role in our understanding of key physical, chemical, and biological features. Using manipulations of Schrödinger’s wavefunction, we describe electron tunneling through orbits. We extend our findings to a biological setting where we theorize an imbalance in exothermic biochemical reactions may contribute to protein damage. Additionally, we posit the cellular environment encourages electron binding among higher principal quantum orbits than traditionally assumed. This model can be one of many explanations for the sporadic nature of neurodegenerative disease where protein damage, misfolding, or aggregation is a key characteristic.

•Jul 5, 2026•0 citations

Quantum in Neurodegeneration: Investigating a Mechanism of Protein Damage

Ashish Kumar, Hetvin Prajapati, Tushar Kumar

Sporadic cases of neurodegenerative disease affect millions globally and are characterized by lack of a single known genetic cause. We used Schrödinger’s wavefunction and de Broglie’s wavelength for a non-relativistic particle to model tunneling among principal quantum orbits. Expanding on this work, we described electron behaviour in the brief moment an atom absorbs energy. We then contextualized these findings in a biological setting, positing an imbalance in energy-emitting biochemical reactions lead to structural fluctuations in proteins. Additionally, we prove the cellular microenvironment encourages bonds and behaviour among principal quantum orbits greater than traditionally assumed. Investigating the origin of sporadic disease is crucial for therapies that target the events preceding aggregation.

•Sep 3, 2026•0 citations

Quantum Theoretical Modeling of Infectious Disease Mechanisms with Emphasis on Tunneling Effects

S. A. Hosseini, R. Usefi, A. A. Mohammadi

Abstract This work emphasized the importance of quantum principles in Biological systems. Specially theoretically explained the mechanisms of infectious disease according to the laws of quantum mechanics, focusing on quantum tunneling. It determines the role of quantum events in microbial processes and demonstrates Schrödinger's prophetic view of quantum theory. Interactions between viruses and cells, as well as enzyme function and binding, are not well explained by traditional lock-and-key methods, while quantum tunneling, which is used to pass electrons through this method, can best demonstrate the function of spiked proteins with cellular receptors.

•Nov 22, 2025•0 citations

Electron Transfers and Holographic Molecules: Why Neuroscientists Should Take Quantum Phenomena into Consideration

Philippe Anglade, Yamina Larabi, Shigeru Tsuji

Discoveries concerning the neurotransmission mode of the nerve impulse contributed a lot to the development of modern neurosciences. Neurons release chemical agents, such as neurotransmitters and neuromodulators, which bind to receptors of their target cells, enabling, thus, propagation of nerve impulse from cell to cell. In the nervous system, intercellular exchanges of information take place as bindings of ions or molecules to receptor proteins. These bindings induce changes in the conformation of the proteins which can, in this way, integrate and memorize physical and chemical alterations affecting the surrounding neurons. The researches on learning and memory are based on these concepts. However, the revolutionary advances in quantum physics allowed new hypotheses to be addressed in the functioning of the nervous system, particularly in the brain. Indeed, new technologies based on the application of quantum mechanics were recently devised, such as scanning tunneling microscopy and transient absorption spectroscopy. The use of these methods revealed that quantum particles, like electrons, might play so far unknown roles in the biological processes. Thus, electron transfers by tunneling effect have been evidenced between molecules of the photosynthetic and respiratory chains, retina and DNA. Moreover, such biophysical investigations established that proteins could function as holographic media, integrating and recording multiple particles emissions. These data suggest that, in the nervous system, a single molecule might integrate and memorize, in the shape of wave interference figures, a gigantic amount of physical and chemical signals arising from its surrounding medium.

NeuroQuantology•May 13, 2014•2 citations

Exploring Quantum in Cancer Biology: A Comprehensive Review of Nontrivial Quantum Events

Ali Ayesha, Naeem, Muhammad Yasir, Selamoglu Zeliha +1 more

This study explores the potential of quantum computing as an alternative information processing approach, utilizing quantum bits (qubits), superposition, and entanglement to significantly expand computational capabilities in the healthcare domain. It is evident that quantum mechanics has become a foundational component in the construction of our contemporary physical reality. This scientific field is distinguished by its rapid advancement and the potential to transform various aspects of our daily lives. In this era, quantum biology is of significant importance and has the potential to act as a transformative force, particularly in the field of medicine, specifically in addressing the challenges posed by cancer. Cancer is defined as a complex and abnormal alteration of cells, orchestrated through intricate signaling pathways. This transformation is characterized by the accumulation of deleterious mutations. The concept of phenocopy, representing genetic mutations influenced by the environment, challenges the linear process line of molecular biology involving DNA, RNA, and proteins. Notwithstanding the augmented focus on quantum biology in recent decades, a plethora of unresolved issues persist within the domain of cancer biology, thereby giving rise to unexplored avenues. Quantum theory has demonstrated its ability to explain models related to biological and biochemical processes, encompassing the effects of carcinogens on genes, the mechanism of interactions between chemotherapy drugs and DNA, and the understanding of DNA mutations and defective protein synthesis. Recent skepticism among quantum physicists regarding the fundamental role of quantum effects in biology has emerged, particularly with regard to open quantum systems and the impact of decoherence on the destruction of coherence necessary for significant quantum effects. The document under scrutiny herein undertakes an investigation of recent studies that are rooted in the principles of quantum physics, with a particular focus on the manner in which these principles apply to the domains of cancer biology and metabolism.

Archives of Razi Institute•Apr 29, 2025•0 citations

A REVIEW OF QUANTUM PHYSICS IN BIOLOGICAL SYSTEMS

Mohamed Nizam Shah, Jeff Patric, M A Vidya +1 more

This review on quantum biology, a burgeoning eld at the intersection of life and the bizarre rules of the quantum world, is investigating how phenomena like tunneling, superposition, and entanglement might inuence biological processes. From the dance of odor molecules and smell receptors, potentially inuenced by tunneling for odor discrimination, to the mind-bending possibility of entangled electrons guiding bird migration, the eld is uncovering a hidden language within life. In photosynthesis, superposition allows light-excited electrons to explore multiple pathways, maximizing their efciency in converting light into energy. Enzymes, the masterminds of countless reactions, might benet from tunneling, allowing substrates to overcome energy hurdles, and coherence, enhancing selectivity. The radical pair mechanism, with its entangled electrons, is a potential explanation for how birds navigate with Earth's magnetic eld. Finally, the article ventures into the uncharted territory of consciousness, pondering the possibility of quantum effects playing a role in neuronal ion channels, though signicant challenges remain in verifying and understanding these effects within the brain's complex environment. Overall, this exciting nascent eld holds the potential to illuminate intricate biological mechanisms and offer glimpses into the enigmatic realm of consciousness.

Indian Journal Of Applied Research•Mar 1, 2024•0 citations
Findings related to quantum mechanics over the last century have had a pivotal role in our understanding of key physical, chemical, and biological features. Using manipulations of Schrödinger’s wavefunction, we describe electron tunneling through orbits. We extend our findings to a biological setting where we theorize an imbalance in exothermic biochemical reactions may contribute to protein damage. Additionally, we posit the cellular environment encourages electron binding among higher principal quantum orbits than traditionally assumed. This model can be one of many explanations for the sporadic nature of neurodegenerative disease where protein damage, misfolding, or aggregation is a key characteristic.
Findings related to quantum mechanics over the last century have had a pivotal role in our understanding of key physical, chemical, and biological features. Using manipulations of Schrödinger’s wavefunction, we describe electron tunneling through orbits. We extend our findings to a biological setting where we theorize an imbalance in exothermic biochemical reactions may contribute to protein damage. Additionally, we posit the cellular environment encourages electron binding among higher principal quantum orbits than traditionally assumed. This model can be one of many explanations for the sporadic nature of neurodegenerative disease where protein damage, misfolding, or aggregation is a key characteristic.
Sporadic cases of neurodegenerative disease affect millions globally and are characterized by lack of a single known genetic cause. We used Schrödinger’s wavefunction and de Broglie’s wavelength for a non-relativistic particle to model tunneling among principal quantum orbits. Expanding on this work, we described electron behaviour in the brief moment an atom absorbs energy. We then contextualized these findings in a biological setting, positing an imbalance in energy-emitting biochemical reactions lead to structural fluctuations in proteins. Additionally, we prove the cellular microenvironment encourages bonds and behaviour among principal quantum orbits greater than traditionally assumed. Investigating the origin of sporadic disease is crucial for therapies that target the events preceding aggregation.
Abstract This work emphasized the importance of quantum principles in Biological systems. Specially theoretically explained the mechanisms of infectious disease according to the laws of quantum mechanics, focusing on quantum tunneling. It determines the role of quantum events in microbial processes and demonstrates Schrödinger's prophetic view of quantum theory. Interactions between viruses and cells, as well as enzyme function and binding, are not well explained by traditional lock-and-key methods, while quantum tunneling, which is used to pass electrons through this method, can best demonstrate the function of spiked proteins with cellular receptors.
Discoveries concerning the neurotransmission mode of the nerve impulse contributed a lot to the development of modern neurosciences. Neurons release chemical agents, such as neurotransmitters and neuromodulators, which bind to receptors of their target cells, enabling, thus, propagation of nerve impulse from cell to cell. In the nervous system, intercellular exchanges of information take place as bindings of ions or molecules to receptor proteins. These bindings induce changes in the conformation of the proteins which can, in this way, integrate and memorize physical and chemical alterations affecting the surrounding neurons. The researches on learning and memory are based on these concepts. However, the revolutionary advances in quantum physics allowed new hypotheses to be addressed in the functioning of the nervous system, particularly in the brain. Indeed, new technologies based on the application of quantum mechanics were recently devised, such as scanning tunneling microscopy and transient absorption spectroscopy. The use of these methods revealed that quantum particles, like electrons, might play so far unknown roles in the biological processes. Thus, electron transfers by tunneling effect have been evidenced between molecules of the photosynthetic and respiratory chains, retina and DNA. Moreover, such biophysical investigations established that proteins could function as holographic media, integrating and recording multiple particles emissions. These data suggest that, in the nervous system, a single molecule might integrate and memorize, in the shape of wave interference figures, a gigantic amount of physical and chemical signals arising from its surrounding medium.
This study explores the potential of quantum computing as an alternative information processing approach, utilizing quantum bits (qubits), superposition, and entanglement to significantly expand computational capabilities in the healthcare domain. It is evident that quantum mechanics has become a foundational component in the construction of our contemporary physical reality. This scientific field is distinguished by its rapid advancement and the potential to transform various aspects of our daily lives. In this era, quantum biology is of significant importance and has the potential to act as a transformative force, particularly in the field of medicine, specifically in addressing the challenges posed by cancer. Cancer is defined as a complex and abnormal alteration of cells, orchestrated through intricate signaling pathways. This transformation is characterized by the accumulation of deleterious mutations. The concept of phenocopy, representing genetic mutations influenced by the environment, challenges the linear process line of molecular biology involving DNA, RNA, and proteins. Notwithstanding the augmented focus on quantum biology in recent decades, a plethora of unresolved issues persist within the domain of cancer biology, thereby giving rise to unexplored avenues. Quantum theory has demonstrated its ability to explain models related to biological and biochemical processes, encompassing the effects of carcinogens on genes, the mechanism of interactions between chemotherapy drugs and DNA, and the understanding of DNA mutations and defective protein synthesis. Recent skepticism among quantum physicists regarding the fundamental role of quantum effects in biology has emerged, particularly with regard to open quantum systems and the impact of decoherence on the destruction of coherence necessary for significant quantum effects. The document under scrutiny herein undertakes an investigation of recent studies that are rooted in the principles of quantum physics, with a particular focus on the manner in which these principles apply to the domains of cancer biology and metabolism.
This review on quantum biology, a burgeoning eld at the intersection of life and the bizarre rules of the quantum world, is investigating how phenomena like tunneling, superposition, and entanglement might inuence biological processes. From the dance of odor molecules and smell receptors, potentially inuenced by tunneling for odor discrimination, to the mind-bending possibility of entangled electrons guiding bird migration, the eld is uncovering a hidden language within life. In photosynthesis, superposition allows light-excited electrons to explore multiple pathways, maximizing their efciency in converting light into energy. Enzymes, the masterminds of countless reactions, might benet from tunneling, allowing substrates to overcome energy hurdles, and coherence, enhancing selectivity. The radical pair mechanism, with its entangled electrons, is a potential explanation for how birds navigate with Earth's magnetic eld. Finally, the article ventures into the uncharted territory of consciousness, pondering the possibility of quantum effects playing a role in neuronal ion channels, though signicant challenges remain in verifying and understanding these effects within the brain's complex environment. Overall, this exciting nascent eld holds the potential to illuminate intricate biological mechanisms and offer glimpses into the enigmatic realm of consciousness.