Practical quantum computing on Noisy Intermediate-Scale Quantum (NISQ) devices is fundamentally bottlenecked by hardware imperfections: errors accumulate quickly and can destroy the interference patterns that quantum algorithms rely on. While full quantum error correction promises fault tolerance, its overhead is prohibitive for near-term processors, and many quantum error mitigation techniques trade this limitation for substantial sampling cost, limited applicability, or per-circuit retraining. We propose an active, learning-based circuit-level correction framework that suppresses errors during execution. Our approach interleaves lightweight single-qubit parameterized quantum circuit (PQC) blocks into a target circuit and predicts their corrective rotation angles directly from the circuit's gate sequence. We formalize this setting as a general parameter prediction problem: learn a model that maps circuits to continuous corrective parameters to minimize the expected discrepancy between the ideal and corrected output distributions over the circuit domain. We implement this with a Transformer-Encoder architecture operating on a sliding-window circuit representation, enabling prediction of corrections in a single forward pass. Across diverse random benchmark circuits, the learned predictor achieves zero-shot correction on unseen instances, eliminating expensive per-circuit tuning at inference time. Empirically, our interleaved corrections substantially improve output distribution fidelity, maintaining state fidelities above 0.99 in regimes where uncorrected executions average between 0.3 and 0.5.
Practical quantum computing on Noisy Intermediate-Scale Quantum (NISQ) devices is fundamentally bottlenecked by hardware imperfections: errors accumulate quickly and can destroy the interference patterns that quantum algorithms rely on. While full quantum error correction promises fault tolerance, its overhead is prohibitive for near-term processors, and many quantum error mitigation techniques trade this limitation for substantial sampling cost, limited applicability, or per-circuit retraining. We propose an active, learning-based circuit-level correction framework that suppresses errors during execution. Our approach interleaves lightweight single-qubit parameterized quantum circuit (PQC) blocks into a target circuit and predicts their corrective rotation angles directly from the circuit's gate sequence. We formalize this setting as a general parameter prediction problem: learn a model that maps circuits to continuous corrective parameters to minimize the expected discrepancy between the ideal and corrected output distributions over the circuit domain. We implement this with a Transformer-Encoder architecture operating on a sliding-window circuit representation, enabling prediction of corrections in a single forward pass. Across diverse random benchmark circuits, the learned predictor achieves zero-shot correction on unseen instances, eliminating expensive per-circuit tuning at inference time. Empirically, our interleaved corrections substantially improve output distribution fidelity, maintaining state fidelities above 0.99 in regimes where uncorrected executions average between 0.3 and 0.5.
Hybridizing machine learning (ML) with quantum computing has become an attractive strategy to increase computational power on Noisy Intermediate Scale Quantum (NISQ) devices. Although these can be potentially quantum advantage devices, their qubit numbers and noise are bounded and there are challenges when it comes to practical quantum circuit realization. This work concentrates on the creation of optimized quantum circuits via ML-based strategies, to enhance the performance of the circuits, to reduce the error rate and to accommodate the particular noise profile of the hardware of NISQ devices. The resulting suboptimal mappings with little or no consideration of noise and hardware topology in traditional quantum compilers can ruin the fidelity of quantum algorithm. Leveraging machine learning, and specifically reinforcement and supervised learning methods, our method learns to optimize compilation strategy for specific quantum hardware architecture. The paper proposes a framework that uses machine learning models to predict qubit mappings, gate decompositions, and transpilation paths that minimize gate depth and error accumulation. We also investigate transfer learning methods for propagating the learned compilation strategies to novel NISQ machines. Such methods are empirically validated on both simulated and real quantum hardware backends, providing evidence of circuit depth, execution time and error reductions. The results show that ML-assisted compilation can achieve better success probabilities for benchmark quantum algorithms like VQE and QAOA than conventional compilers. Furthermore, the work examines the interpretability of ML models providing hardware-aware optimization recommendations and understanding the noise patterns and methods of error correction. Our work highlights the key role of ML for transferring between theoretical quantum algorithms and their practical NISQ implementations. This integration boosts the immediate applicability of existing quantum devices and provides a basis for adaptive and scalable likelihood-based compilation for the era of fault-tolerant quantum computation. Our results motivate further investigation of hybrid classical-quantum workflows, in which ML iteratively improves compilation in accordance with changing hardware noise and capabilities. By improving quantum circuit compilation onNISQ computers, this work is taking steps toward the realization of quantum advantage in application scenarios such as optimization, cryptography, and quantum simulation without needing to wait for fully fault-tolerant large-scale quantum computers.
Abstract Quantum computing has recently emerged as a novel paradigm for solving problems otherwise intractable on classical computers, yet the practical progress of quantum computers is severely impacted by noise, decoherence, and imperfect gate operations in Noisy Intermediate-Scale Quantum (NISQ) devices. Specific to IBM Quantum hardware, imperfections due to readout error, gate errors, and device drift, which depends on time, resolves limits for the accuracy of outputs from our algorithms. The mitigation strategies currently used, for example, Measurement Error Mitigation (MEM), Zero Noise Extrapolation (ZNE), and Clifford Data Regression (CDR), offer improvement over raw, unmitigated outputs, but they are static and not dynamic; the reduction of noise in within an NISQ device is temporal and can vary in patterns that are non-zero. In addition to this, using the conventional methods provides inconsistent and suboptimal results.This study will provide enhanced reliability with respect to performing quantum computation on IBM Quantum hardware with a unique mitigation framework that is adaptive and computationally efficient for a high-fidelity output. The problem taken on here is the failure of existing error mitigation strategies to provide adaptive noise compensation, as they assume a statically-distributed error, despite the performance-related characteristics already being documented in regards to calibration drift and variation over time.To achieve this, we propose a Hybrid Adaptive Error Mitigation (HAEM) approach that includes baseline measurement error mitigation and an additional correction layer that utilizes realtime calibration information, along with lightweight machine learning models. The approach can be broken down into three steps: (i) perform standard measurement error mitigation to reduce classical readout noise, (ii) execute compact calibration circuits, such as Bell states, GHZ states and Clifford benchmarks to capture then current error profile of the device, and (iii) use a lightweight machine learning model (having been trained on historical and newest calibration data) to dynamically change the mitigation weights applied for the target quantum algorithm. All implementation is done using Qiskit Runtime to ensure low-latency execution, and we completed experiments on both Qiskit Aer noisy simulators and IBM Quantum devices.Initial results suggest HAEM improved the outputs of quantum algorithms' fidelity compared to the unmitigated runs and the baseline measurement error mitigation (MEM) runs. On the noisy simulators, HAEM increased fidelity from a raw performance of 0.65 to 0.87, nearly a 34% improvement. In fairer hardware-like scenarios, fidelity-on-average was persistently 12% better than MEM, with nearly equal time duration for the additional adaptive measurements. The adaptive aspect of HAEM consistently supported subsequent calibration cycles of the device and was effective to continue providing fidelity improvements despite the static mitigation performance degrading.To sum up, the proposed HAEM framework is a modern and viable alternative for error mitigation which brings together the benefits of baseline approaches with corrections that are driven by fixed-function error-corrective, adaptive learning. As both learning-based and standard baseline approaches can only achieve fixed levels of performance, HAEM, through its use of noise mitigation both at execution time and through correlating it with standard data, provides a route towards reliable quantum computations on current IBM hardware. HAEM also presents a contribution to the NISQ error-resilient landscape, and however it is intended that it will continue to improve future applications of hybrid workflows of quantum and classical computation where error mitigation and resilience is important.
Adaptive quantum computing control is important for the stability and efficiency of quantum systems, especially in the presence of dynamic environmental noise and hardware fluctuations. We present a unified strategy for machine learning (ML) techniques to improve adaptive quantum control in two main directions: optimization speed and out-of-sample error. Here, we propose a hybrid learning method combining reinforcement learning (RL), deep neural networks (DNNs), and quantum-inspired models to actively and adaptively update quantum gate parameters and error mitigation strategies on the fly. Embedding of quantum noise models directly into the learning allows the system to predict and correct for decoherence, gate errors and measurement inaccuracy before they affect computational fidelity. Using extensive simulations as well as experimental validation on noisy intermediate-scale quantum (NISQ) processors, our improved ML model achieves a substantially higher fidelity and robustness compared to standard model-free and static control approaches. We introduce a novel feedback-loop mechanism based on online learning algorithms enabling the system to adjust for changing noise profiles and hardware drift without retraining. The optimization part uses metaheuristic methods to quickly converge to control parameters that perform well, and the error prevention mechanism features anomaly detection and prediction correction layers to minimize the effects of cumulative decoherence. The results demonstrate that our adaptive control framework can be used to not only speed up the convergence in training quantum algorithms, but also sustain the performance of gates against error at a variety of error rates with the reduction of the real-time impact of the error up to 35 %. This work highlights the promise of machine learningaugmented quantum control for improving reliability and scalability in quantum computing and serves as a stepping stone for future incorporation with fault-tolerant designs.
Quantum computing offers exponential advantages for problems in cryptography, optimization, and quantum simulation, yet the practicality of current Noisy Intermediate-Scale Quantum (NISQ) devices is severely constrained by decoherence, gate imperfections, and measurement noise. Conventional quantum error correction (QEC) codes such as Steane and surface codes impose large qubit overheads and require high-fidelity logical operations, making them unsuitable for near-term hardware. To address this gap, this work introduces ML-QEM, an adaptive quantum error mitigation framework that employs machine learning to identify and correct dominant Pauli error patterns in real time using only 3–5 ancillary qubits. By integrating Qiskit Aer noise modeling with a lightweight TensorFlow-based classifier, ML-QEM learns device-specific noise characteristics and applies targeted recovery operations with minimal latency. Evaluations across depolarizing, amplitude damping, and thermal relaxation noise models demonstrate a 28.4% average fidelity improvement, 60–84% lower overhead than Steane and surface codes, and a classical processing delay of only 21.7 ms. ML-QEM thus provides an effective and resource-efficient pathway toward enhancing quantum computation fidelity in the NISQ era.
The pursuit of high-fidelity digital quantum simulation is fundamentally constrained by the inevitable presence of noise in current and near-term quantum processors. While quantum error correction ultimately promises fault-tolerance, its substantial qubit overhead renders it impractical for the noisy intermediate-scale quantum (NISQ) era. This research addresses the critical gap between hardware imperfections and simulation accuracy by designing systematic, resource-efficient machine learning (ML) error-mitigation protocols tailored specifically for digital quantum simulation. Unlike generic error-suppression methods, our approach exploits the unique structural properties of simulated quantum dynamics—including time-translation invariance, locality of interactions, and conserved quantities—to inform the training of lightweight neural networks and Gaussian process regressors. We develop a hybrid framework that combines randomized compiling with data-driven noise-inversion models, enabling real-time estimation and subtraction of both coherent and incoherent errors without exponential sampling overhead. Through extensive numerical benchmarks on spin-chain and Fermi-Hubbard models, we demonstrate that our ML protocols achieve up to an order-of-magnitude reduction in infidelity compared to standard probabilistic error cancellation and zero-noise extrapolation, while requiring fewer calibration circuits. Furthermore, we introduce an adaptive online learning scheme that continuously refines the mitigation model during the simulation runtime, automatically adjusting to time-dependent drift in hardware noise. Our results establish a practical pathway toward scalable, high-accuracy quantum simulations on existing devices, with implications for condensed matter physics, quantum chemistry, and the development of quantum advantage benchmarks.
Noise in quantum hardware is the primary obstacle to realizing the transformative potential of quantum computing. Quantum error mitigation (QEM) offers a promising pathway to enhance computational accuracy on near-term devices, yet existing methods face a difficult trade-off between performance, resource overhead, and theoretical guarantees. In this work, we introduce neighbor-informed learning (NIL), a versatile and scalable QEM framework that unifies and strengthens existing methods such as zero-noise extrapolation (ZNE) and probabilistic error cancellation (PEC), while offering improved flexibility, accuracy, efficiency, and robustness.
NIL learns to predict the ideal output of a target quantum circuit from the noisy outputs of its structurally related ``neighbor'' circuits. A key innovation is our 2-design training method, which generates training data for our machine learning model. In contrast to conventional learning-based QEM protocols that create training circuits by replacing non-Clifford gates with uniformly random Clifford gates, our approach achieves higher accuracy and efficiency, as demonstrated by both theoretical analysis and numerical simulation. Furthermore, we prove that the required size of the training set scales only \emph{logarithmically} with the total number of neighbor circuits, enabling NIL to be applied to problems involving large-scale quantum circuits. Our work establishes a theoretically grounded and practically efficient framework for QEM, paving a viable path toward achieving quantum advantage on noisy hardware.