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IEEE Region 10 Conference (TENCON)

Design and Optimization of Complex Quantum Circuits Targeting Near-Term Quantum Processors Using Custom Algorithms and Qiskit Transpiler

Kazi Redwan, Mustakim Ahmed, Md. Faruk Abdullah Al Sohan, Sajedul Islam, Birbal Tamang, Rasmila Lama, Ruja Shrestha, Abu Shufian

Published Oct 27, 2025• 0 citations
Publisher

Abstract

Quantum computing faces challenges such as noise, short coherence time, and limited qubit connections. These challenges worsen as quantum circuits become more complex. One major issue is the increasing depth of quantum circuits. This research proposes an optimization framework targeting depth and gate count reduction in quantum circuits, specifically for Noisy Intermediate-Scale Quantum (NISQ) devices. The proposed approach combines unitary merging of single-qubit gates, CNOT cancellation, gate commuting, and rotation gate rewriting strategies. Consecutive gates acting on the same qubit, such as$R_{x}\left(\theta_{1}\right) \cdot R_{x}\left(\theta_{2}\right)$, are algebraically merged into a single rotation, while pairs of redundant CNOT gates are eliminated based on gate identity relations. The technique is implemented using Qiskit and validated across five diverse circuits including complex, random, and multi-qubit configurations. Experimental results show an average depth reduction of 33.33% and gate count reduction of 32.14%, with runtime improvement of up to 25%. For instance, an input circuit with a depth of 7 and gate count of 11 was reduced to a depth of 2 and 4 gates. All optimized circuits preserve functional correctness with a fidelity$F \geq 0.99$. High-resolution circuit diagrams are presented to visually demonstrate improvements before and after optimization. Additionally, global phase shifts such as$e^{i \pi / 4}$are preserved or analytically characterized where relevant. This work enhances the viability of quantum computations on near-term hardware and opens pathways for future AI-driven quantum optimizations.

DOI
10.1109/tencon66050.2025.11375021

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The current phase of quantum computing is in the Noisy Intermediate-Scale Quantum (NISQ) era. On NISQ devices, two-qubit gates such as CNOTs are much noisier than single-qubit gates, so it is essential to minimize their count. Quantum circuit synthesis is a process of decomposing an arbitrary unitary into a sequence of quantum gates, and can be used as an optimization tool to produce shorter circuits to improve overall circuit fidelity. However, the time-to-solution of synthesis grows exponentially with the number of qubits. As a result, synthesis is intractable for circuits on a large qubit scale. In this paper, we propose a hierarchical, block-by-block optimization framework, QGo, for quantum circuit optimization. Our approach allows an exponential cost optimization to scale to large circuits. QGo uses a combination of partitioning and synthesis: 1) partition the circuit into a sequence of independent circuit blocks; 2) re-generate and optimize each block using quantum synthesis; and 3) re-compose the final circuit by stitching all the blocks together. We perform our analysis and show the fidelity improvements in three different regimes: small-size circuits on real devices, medium-size circuits on noise simulations, and large-size circuits on analytical models. Using a set of NISQ benchmarks, we show that QGo can reduce the number of CNOT gates by 29.9% on average and up to 50% when compared with industrial compilers such as t|ket>. When executed on the IBM Athens system, shorter depth leads to higher circuit fidelity. We also demonstrate the scalability of our QGo technique to optimize circuits of 60+ qubits. Our technique is the first demonstration of successfully employing and scaling synthesis in the compilation toolchain for large circuits. Overall, our approach is robust for direct incorporation in production compiler toolchains.
The current phase of quantum computing is in the Noisy Intermediate-Scale Quantum (NISQ) era. On NISQ devices, two-qubit gates such as CNOTs are much noisier than single-qubit gates, so it is essential to minimize their count. Quantum circuit synthesis is a process of decomposing an arbitrary unitary into a sequence of quantum gates, and can be used as an optimization tool to produce shorter circuits to improve overall circuit fidelity. However, the time-to-solution of synthesis grows exponentially with the number of qubits. As a result, synthesis is intractable for circuits on a large qubit scale. In this paper, we propose a hierarchical, block-by-block optimization framework, QGo, for quantum circuit optimization. Our approach allows an exponential cost optimization to scale to large circuits. QGo uses a combination of partitioning and synthesis: 1) partition the circuit into a sequence of independent circuit blocks; 2) re-generate and optimize each block using quantum synthesis; and 3) re-compose the final circuit by stitching all the blocks together. We perform our analysis and show the fidelity improvements in three different regimes: small-size circuits on real devices, medium-size circuits on noise simulations, and large-size circuits on analytical models. Using a set of NISQ benchmarks, we show that QGo can reduce the number of CNOT gates by 29.9% on average and up to 50% when compared with industrial compilers such as t|ket>. When executed on the IBM Athens system, shorter depth leads to higher circuit fidelity. We also demonstrate the scalability of our QGo technique to optimize circuits of 60+ qubits. Our technique is the first demonstration of successfully employing and scaling synthesis in the compilation toolchain for large circuits. Overall, our approach is robust for direct incorporation in production compiler toolchains.
Quantum circuit optimization - the process of transforming a quantum circuit into an equivalent one with reduced time and space requirements - is crucial for maximizing the utility of current and near-future quantum devices. While most automated optimization techniques focus on transforming circuits into equivalent ones that implement the same unitary, we show that substantial new opportunities for resource reduction can be achieved by (1) allowing approximate local transformations and (2) employing mixed quantum channels to approximate pure circuits. Our novel automated protocol for approximate circuit rewriting is a refined evolution of automated optimization techniques based on the ZX-calculus, where we add a greedy strategy that selectively replaces ZX-diagrams with small phase angles with stochastic mixtures of the identity and carefully chosen over-rotations, which are designed to reduce the overall gate count in expectation while staying within a strict error budget. This approach yields modest two-qubit gate count reduction in random quantum circuits, and achieves a substantial reduction in structured circuits such as the quantum Fourier transform. Fundamentally, our protocol converts experimental noise due to gate applications into deliberately engineered random noise, outperforming many other approximation methods on average. These results highlight the potential of mixed-channel approximations to enhance future quantum circuit performance, suggesting new directions for resource-aware automated quantum compilation beyond pure unitary channels.
The current phase of quantum computing is in the Noisy Intermediate-Scale Quantum (NISQ) era. On NISQ devices, two-qubit gates such as CNOTs are much noisier than single-qubit gates, so it is essential to minimize their count. Quantum circuit synthesis is a process of decomposing an arbitrary unitary into a sequence of quantum gates, and can be used as an optimization tool to produce shorter circuits to improve overall circuit fidelity. However, the time-to-solution of synthesis grows exponentially with the number of qubits. As a result, synthesis is intractable for circuits on a large qubit scale. In this paper, we propose a hierarchical, block-by-block opti-mization framework, QGo, for quantum circuit optimization. Our approach allows an exponential cost optimization to scale to large circuits. QGo uses a combination of partitioning and synthesis: 1) partition the circuit into a sequence of independent circuit blocks; 2) re-generate and optimize each block using quantum synthesis; and 3) re-compose the final circuit by stitching all the blocks together. We perform our analysis and show the fidelity improvements in three different regimes: small-size circuits on real devices, medium-size circuits on noisy simulations, and large-size circuits on analytical models. Our technique can be applied after existing optimizations to achieve higher circuit fidelity. Using a set of NISQ benchmarks, we show that QGo can reduce the number of CNOT gates by 29.9% on average and up to 50% when compared with industrial compiler optimizations such as t|ket). When executed on the IBM Athens system, shorter depth leads to higher circuit fidelity. We also demonstrate the scalability of our QGo technique to optimize circuits of 60+ qubits, Our technique is the first demonstration of successfully employing and scaling synthesis in the compilation tool chain for large circuits. Overall, our approach is robust for direct incorporation in production compiler toolchains to further improve the circuit fidelity.
Quantum computing, leveraging the principles of superposition and entanglement, holds the potential to revolutionize computational problem-solving across a wide array of fields, from cryptography to complex system simulations. However, unlocking the full power of quantum computing requires the development of advanced quantum compilation techniques that can efficiently map high-level algorithms onto physical quantum hardware. This paper delves into state-of-the-art optimization strategies within quantum compilers, with a particular focus on methods such as Relaxed Peephole Optimization (RPO), gate reordering techniques for the Quantum Approximate Optimization Algorithm (QAOA), and reinforcement learning (RL)-driven frameworks. It also explores innovative approaches like distributed quantum compilation, parity quantum optimization, and the Paulihedral framework, all designed to minimize gate counts, reduce circuit depth, and optimize overall resource utilization. A key contribution of this work is the introduction of error mitigation techniques that enhance the fidelity and scalability of quantum circuits, particularly on noisy intermediate-scale quantum (NISQ) devices. Through comprehensive empirical evaluations across a variety of quantum algorithms, the paper demonstrates significant improvements in critical performance metrics such as circuit depth, gate count, and execution efficiency, providing a promising direction for optimizing quantum circuit design tailored to diverse quantum hardware platforms.
We present an analysis of quantum circuit fidelity across the full compilation stack, from high-level gate optimization through pulse-level control. We connect a C++ circuit optimizer to a per-gate Lindblad master-equation fidelity model whose decoherence channels are cross-validated against qiskit-dynamics and whose absolute predictions are benchmarked against execution on real hardware. Across a campaign of 4,452 experiment runs over 371 benchmark circuits, gate cancellation provides the dominant improvement (d=1.66d = 1.66d=1.66, 72% of circuits improved), while circuit size and pulse duration are the strongest negative predictors of process fidelity (input gates r=−0.78r = -0.78r=−0.78; pulse duration r=−0.73r = -0.73r=−0.73, R2=0.53R^2 = 0.53R2=0.53). A formal ablation study shows that pass ordering has no significant effect on two-qubit gate reduction (Kruskal--Wallis p=0.302p = 0.302p=0.302). Comparing against Qiskit transpilation levels, we show that two-qubit gate count, not total gate count, is the hardware-relevant metric: our optimizer attains superior two-qubit reduction on structured circuits (87.8% on QFT, 100% on QAOA) whereas Qiskit's larger total-gate reduction is dominated by single-qubit (u3u_3u3​) consolidation. Finally, executing eight circuits on the IQM Resonance Garnet processor (8/8 jobs completed, job identifiers released) reveals that the model is a consistent upper bound: it preserves the relative difficulty ordering of circuits but overestimates absolute fidelity by a mean of 0.49, quantifying the error budget (crosstalk, leakage, readout) outside a T1T_1T1​/T2T_2T2​/depolarizing model. We release the framework, data, and scripts as open source.