The rapid advancement of Noisy Intermediate-Scale Quantum (NISQ) devices has driven the need for efficient design automation tools that can translate complex engineering models into executable quantum circuits. This study explores the development of automated quantum circuit design frameworks focused on gate optimization and noise-aware compilation, enabling practical quantum computation for engineering applications such as optimization, simulation, and control systems. Traditional circuit design methods often fail to account for hardware constraints, decoherence, and gate infidelity, which significantly affect computational accuracy on NISQ devices. To address these challenges, this research introduces a hybrid automation approach combining quantum transpilation, variational circuit pruning, and error-aware synthesis algorithms to enhance circuit reliability and scalability. The framework integrates quantum-classical co-design principles to optimize both logical and physical circuit layers, leveraging hardware-specific calibration data to adapt compilation strategies dynamically. Through simulations and benchmark analysis, the proposed system demonstrates significant improvements in quantum resource utilization, error mitigation, and gate depth reduction compared to conventional compilation methods. This work underscores the growing importance of design automation in quantum engineering, where algorithmic efficiency must be harmonized with physical constraints to realize functional and scalable quantum workflows. By establishing a methodology for gate-level optimization and noise-adaptive design, the study contributes to bridging the gap between theoretical quantum algorithms and real-world engineering implementations within the NISQ computing era.
The rapid advancement of Noisy Intermediate-Scale Quantum (NISQ) devices has driven the need for efficient design automation tools that can translate complex engineering models into executable quantum circuits. This study explores the development of automated quantum circuit design frameworks focused on gate optimization and noise-aware compilation, enabling practical quantum computation for engineering applications such as optimization, simulation, and control systems. Traditional circuit design methods often fail to account for hardware constraints, decoherence, and gate infidelity, which significantly affect computational accuracy on NISQ devices. To address these challenges, this research introduces a hybrid automation approach combining quantum transpilation, variational circuit pruning, and error-aware synthesis algorithms to enhance circuit reliability and scalability. The framework integrates quantum-classical co-design principles to optimize both logical and physical circuit layers, leveraging hardware-specific calibration data to adapt compilation strategies dynamically. Through simulations and benchmark analysis, the proposed system demonstrates significant improvements in quantum resource utilization, error mitigation, and gate depth reduction compared to conventional compilation methods. This work underscores the growing importance of design automation in quantum engineering, where algorithmic efficiency must be harmonized with physical constraints to realize functional and scalable quantum workflows. By establishing a methodology for gate-level optimization and noise-adaptive design, the study contributes to bridging the gap between theoretical quantum algorithms and real-world engineering implementations within the NISQ computing era.
The rapid evolution of Noisy Intermediate-Scale Quantum (NISQ) devices has intensified the need for robust compilation strategies capable of mitigating hardware-induced errors while maximizing computational efficiency. Quantum compilers play a pivotal role in translating high-level quantum algorithms into hardware-executable instructions, yet they face significant challenges related to qubit connectivity constraints, limited coherence times, and stochastic noise. This paper examines error-resilient quantum compiler design for efficient qubit mapping, gate optimization, and noise mitigation in NISQ-era devices, proposing a framework that integrates topology-aware mapping, adaptive gate synthesis, and probabilistic error suppression techniques. By synthesizing advances in quantum circuit optimization, hardware-aware scheduling, and hybrid classical–quantum error correction strategies, the study evaluates how compiler-level innovations can substantially enhance execution fidelity and resource efficiency. The findings suggest that intelligent compiler architectures are critical enablers of practical quantum advantage during the transitional NISQ phase, bridging theoretical algorithm design with real-world hardware constraints.
Noisy Intermediate-Scale Quantum (NISQ) devices are promising platforms for practical quantum computing, but their performance is significantly affected by limited qubit availability, gate errors, decoherence, circuit depth, and hardware-dependent noise. Conventional quantum circuits are generally designed and optimized before execution and may not respond effectively to changing hardware conditions during computation. This research proposes a Self-Adaptive Quantum Circuit framework that dynamically modifies quantum circuits according to the current computational resources and noise characteristics of NISQ devices. The proposed framework monitors parameters such as qubit fidelity, gate error rates, circuit depth, execution time, and resource availability, and automatically selects suitable circuit configurations to improve computational performance. Adaptive mechanisms can be employed to reduce unnecessary gates, optimize qubit utilization, and mitigate the impact of hardware noise while maintaining the required computational accuracy. The framework will be evaluated using simulation platforms and available NISQ quantum hardware, comparing adaptive circuits with conventional static circuits using metrics such as accuracy, fidelity, circuit depth, gate count, execution time, and error rate. The expected outcome is a resource-efficient and noise-aware quantum circuit optimization approach capable of improving the reliability and performance of quantum applications on near-term quantum hardware. The proposed research aims to contribute toward more practical, flexible, and hardware-aware quantum computing systems for NISQ-era applications. Keywords: NISQ Computing, Self-Adaptive Quantum Circuits, Quantum Circuit Optimization, Quantum Error Mitigation, Quantum Noise, Quantum Computing.
Quantum computing, leveraging the principles of superposition and entanglement, holds the potential to revolutionize computational problem-solving across a wide array of fields, from cryptography to complex system simulations. However, unlocking the full power of quantum computing requires the development of advanced quantum compilation techniques that can efficiently map high-level algorithms onto physical quantum hardware. This paper delves into state-of-the-art optimization strategies within quantum compilers, with a particular focus on methods such as Relaxed Peephole Optimization (RPO), gate reordering techniques for the Quantum Approximate Optimization Algorithm (QAOA), and reinforcement learning (RL)-driven frameworks. It also explores innovative approaches like distributed quantum compilation, parity quantum optimization, and the Paulihedral framework, all designed to minimize gate counts, reduce circuit depth, and optimize overall resource utilization. A key contribution of this work is the introduction of error mitigation techniques that enhance the fidelity and scalability of quantum circuits, particularly on noisy intermediate-scale quantum (NISQ) devices. Through comprehensive empirical evaluations across a variety of quantum algorithms, the paper demonstrates significant improvements in critical performance metrics such as circuit depth, gate count, and execution efficiency, providing a promising direction for optimizing quantum circuit design tailored to diverse quantum hardware platforms.
Hybridizing machine learning (ML) with quantum computing has become an attractive strategy to increase computational power on Noisy Intermediate Scale Quantum (NISQ) devices. Although these can be potentially quantum advantage devices, their qubit numbers and noise are bounded and there are challenges when it comes to practical quantum circuit realization. This work concentrates on the creation of optimized quantum circuits via ML-based strategies, to enhance the performance of the circuits, to reduce the error rate and to accommodate the particular noise profile of the hardware of NISQ devices. The resulting suboptimal mappings with little or no consideration of noise and hardware topology in traditional quantum compilers can ruin the fidelity of quantum algorithm. Leveraging machine learning, and specifically reinforcement and supervised learning methods, our method learns to optimize compilation strategy for specific quantum hardware architecture. The paper proposes a framework that uses machine learning models to predict qubit mappings, gate decompositions, and transpilation paths that minimize gate depth and error accumulation. We also investigate transfer learning methods for propagating the learned compilation strategies to novel NISQ machines. Such methods are empirically validated on both simulated and real quantum hardware backends, providing evidence of circuit depth, execution time and error reductions. The results show that ML-assisted compilation can achieve better success probabilities for benchmark quantum algorithms like VQE and QAOA than conventional compilers. Furthermore, the work examines the interpretability of ML models providing hardware-aware optimization recommendations and understanding the noise patterns and methods of error correction. Our work highlights the key role of ML for transferring between theoretical quantum algorithms and their practical NISQ implementations. This integration boosts the immediate applicability of existing quantum devices and provides a basis for adaptive and scalable likelihood-based compilation for the era of fault-tolerant quantum computation. Our results motivate further investigation of hybrid classical-quantum workflows, in which ML iteratively improves compilation in accordance with changing hardware noise and capabilities. By improving quantum circuit compilation onNISQ computers, this work is taking steps toward the realization of quantum advantage in application scenarios such as optimization, cryptography, and quantum simulation without needing to wait for fully fault-tolerant large-scale quantum computers.
Resource-efficient computation is of central importance in the noisy intermediate-scale quantum (NISQ) era, where decoherence, gate errors, and restricted qubit connectivity severely limit the reliable execution of quantum algorithms. In this work, we demonstrate that incorporating circuit design considerations is crucial for developing resource-efficient variational quantum algorithms. By focusing on the Hadamard test circuit architecture, hardware-aware qubit connectivity, and problem-specific adaptive framework, we analyze how circuit design constraints can systematically reduce the measurement overhead associated with repeated evaluations of the candidate gate pool in adaptive algorithms. Specifically, we demonstrate reductions in the required measurement resources ranging from at least 25% to as high as 50% - 55%. To assess the effectiveness of our approach, we investigate the ground state problem of the nonlinear Schrödinger equation. Overall, our work contributes to resource-friendly strategies for quantum computation and underscores that algorithmic frameworks should systematically integrate circuit design constraints with hardware-aware and problem-specific structures to enhance the practical feasibility of quantum devices in the NISQ era.
Quantum circuit compilation is a critical step in realizing quantum algorithms on real quantum hardware. Traditional compilation methods often employ static optimization strategies, neglecting the unique constraints and characteristics of the target quantum device. This paper introduces a novel adaptive quantum circuit compilation framework designed to dynamically adjust circuit designs based on hardware-specific information, aiming to minimize gate count and, consequently, error rates. The core of the framework lies in integrating a hardware simulator directly within the compilation process. This allows the compiler to evaluate the performance of various circuit designs—considering factors like qubit connectivity, gate fidelity, and decoherence models—before committing to a final layout. The proposed approach represents a shift from static to adaptive optimization, providing a more nuanced and effective strategy for translating quantum algorithms into executable code on diverse quantum hardware platforms. This research demonstrates a significant potential improvement in quantum circuit efficiency and fidelity, addressing a key bottleneck in the advancement of quantum computing.