Classical imaging works by scattering photons from an object to be imaged, and achieves resolution scaling as 1/t, with t the imaging time. By contrast, the laws of quantum mechanics allow one to utilize quantum coherence to obtain imaging resolution that can scale as quickly as 1/t -- the so-called ``Heisenberg limit.'' However, ambiguities in the obtained signal often preclude taking full advantage of this quantum enhancement, while imaging techniques designed to be unambiguous often lose this optimal Heisenberg scaling. Here we demonstrate an imaging technique which combines unambiguous detection of the target with Heisenberg scaling of the resolution. We also demonstrate a binary search algorithm which can efficiently locate a coherent target using the technique, resolving a target trapped ion to within 0.3% of the 1/e2 diameter of the excitation beam.
In fluorescence imaging and detection, undesired fluorescence interference (such as autofluorescence) often hampers the contrast of the image and even prevents the identification of structures of interest. Here, we develop a quantum coherent modulation-enhanced (QCME) single-molecule imaging microscopy (SMIM) to substantially eliminate the strong fluorescence interference, based on manipulation of the excited-state population probability of a single molecule. By periodically modulating the phase difference between the ultrashort pulse pairs and performing a discrete Fourier transform of the arrival time of emitted photons, the decimation of single molecules from strong interference in QCME-SMIM has been clearly determined, where the signal-to-interference ratio is enhanced by more than 2 orders of magnitude. This technique, confirmed to be universal to organic dyes and linked with biomacromolecules, paves the way to high-contrast bioimaging under unfavorable conditions.
Ghost imaging is an imaging technique in which the image of an object is revealed only in the correlation measurement between two beams of light, whereas the individual measurements contain no imaging information. Normally, the resolution of the image, which even exceeds the Rayleigh limit, is shown to be related to the transverse coherent length (lc) of the speckle pattern. In this Letter, we demonstrate experimentally that the speckle size can be compressed by a coherent population trapping (CPT) process in atom vapor, and the resolution of GI can be greatly enhanced by the CPT process. The technique we exploit is quite efficient and robust, and it may be useful in the field of quantum and classical two-photon imaging, all-optical image processing, and quantum communication.