Accurate disease diagnosis is becoming a critical challenge owing to the limited success of classical machine-learning approaches, especially in classification problems. Accurate and rapid brain tumor classification in medical diagnosis could aid in early detection and treatment planning. This paper presents a novel quantum-enhanced machine learning approach using a Quantum Support Vector Machine (QSVM) and Variational Quantum Classifier (VQC) models for improved tumor classification. ZFeatureMap is deployed for the conversion of classical data points to quantum space, as it is found to be most suitable for the characteristics of the brain tumor dataset and provides a balance between accuracy, efficiency, and computational feasibility. The QSVM and VQC models are implemented on a publicly available brain tumor dataset, demonstrating significant improvement over classical algorithms. Both models were implemented on a 32-qubit quantum simulator and a seven-qubit quantum computer. The simulation results indicate that the QSVM-based model is 3.62% more accurate and 60.4 times faster, while the VQC-based model is 2.49% more accurate and twice as fast as classical SVM. The findings suggest that quantum-enhanced machine learning has the scope to revolutionize medical diagnosis with more precise and faster results.
Accurate disease diagnosis is becoming a critical challenge owing to the limited success of classical machine-learning approaches, especially in classification problems. Accurate and rapid brain tumor classification in medical diagnosis could aid in early detection and treatment planning. This paper presents a novel quantum-enhanced machine learning approach using a Quantum Support Vector Machine (QSVM) and Variational Quantum Classifier (VQC) models for improved tumor classification. ZFeatureMap is deployed for the conversion of classical data points to quantum space, as it is found to be most suitable for the characteristics of the brain tumor dataset and provides a balance between accuracy, efficiency, and computational feasibility. The QSVM and VQC models are implemented on a publicly available brain tumor dataset, demonstrating significant improvement over classical algorithms. Both models were implemented on a 32-qubit quantum simulator and a seven-qubit quantum computer. The simulation results indicate that the QSVM-based model is 3.62% more accurate and 60.4 times faster, while the VQC-based model is 2.49% more accurate and twice as fast as classical SVM. The findings suggest that quantum-enhanced machine learning has the scope to revolutionize medical diagnosis with more precise and faster results.
Early and accurate diagnosis of breast cancer plays a critical role in improving patient survival rates and reducing treatment costs. Classical machine learning algorithms such as Logistic Regression and Support Vector Machines (SVM) have demonstrated strong performance in medical diagnosis tasks; however, their scalability and representational limits motivate the exploration of emerging paradigms. Quantum Machine Learning (QML), particularly Variational Quantum Classifiers (VQC), has recently gained attention due to its potential to model complex decision boundaries using quantum circuits. This paper presents a comparative analysis between a Variational Quantum Classifier and classical machine learning models for binary breast cancer classification. The study employs dimensionality-reduced clinical data and evaluates model performance using accuracy, confusion matrices, decision boundary visualization, Principal Component Analysis (PCA), and Receiver Operating Characteristic (ROC) curves. Experimental results indicate that the VQC achieves competitive performance with classical approaches, demonstrating its feasibility for small-scale medical datasets and highlighting the promise of quantum-enhanced learning in healthcare applications.
Quantum computing is an emerging field that can effectively solve several machine learning problems. The immensely growing data size has begun to create barriers for classical machine learning algorithms. Quantum computers proficiently handle and process big data composed of metrics and vectors. This paper presents the quantum machine learning model based on quantum support vector machines (QSVM) to classify brain tumours into malignant and benign. The dataset used in this experiment is Brats 2015, available on Kaggle. The QSVM-based model was run on real-time quantum machines and simulators to extract the performance metrics in terms of accuracy and execution time. The QSVM classification model is compared with its classical SVM equivalent. The kernel-based QSVM model implementation on a 32-qubit quantum simulator was 188 times faster with 95% accuracy which is 1.60% better than the classical equivalent. Similarly, the model takes 24.19% less time than the classical SVM model when realized on a 5-qubit real-time superconducting processor with the same accuracy. Hence, the results reveal that quantum machine learning models implemented on quantum computers outperformed their classical equivalents.
Quantum support vector machines (QSVMs) are a novel approach for solving classification problems, combining the principles of quantum computing with the support vector machine algorithm. In this study, we applied a QSVM to the Breast Cancer Wisconsin (Original) data set to classify tumors as benign or malignant. Our results showed that the QSVM outperformed classical support vector machines in terms of classification accuracy, achieving a success rate of 100% while classical SVM shows almost perfect result with its accuracy 95%. Additionally, the QSVM required significantly less training time compared to the classical SVM. These results demonstrate the potential of QSVMs for solving complex classification problems in the field of medical diagnosis.
Brain tumor image classification is an essential pre-processing task for tumor diagnosis and treatment planning. In medical imaging, quantum computing analyse medical imaging data, offering potential speedups and new representations compared to classical methods. The brain images are transformed through resizing and normalization to a uniform 32 × 32 × 3 resolution. Subsequently, these processed images are converted into vectors to enable encoding into quantum states. The feature set is reduced using Principal Component Analysis (PCA) to ensure compatibility with the restricted qubit count in the quantum circuits. Through amplitude encoding, these vectors are mapped to quantum states, allowing for a compact and efficient data representation within the quantum domain. A parameterized Variational Quantum Circuit(VQC), consisting of entangling gates and trainable rotations, processes the encoded quantum states to learn features that can effectively discriminate between classes. The loss is calculated from the measured expectation values of Pauli-Z observables and optimized using classical gradient descent, where the objective function is the mean squared error. The trained quantum model is designed for multi-class classification, specifically distinguishing between meningioma, glioma tumors, pituitary tumors, and the absence of a tumor. The outcome of this proposed work demonstrates the VQC’s advantage over classical baselines, including Random Forest, and Support Vector Machine (SVM) and Multi-Layer Perceptron (MLP). The VQC achieved the highest accuracy of 95% and the best robustness (Specificity 0.983). Crucially, the VQC accomplished this using only 24 trainable parameters, showcasing a significant increase in parameter efficiency compared to the classical models. The novelty of this work is the quantitative demonstration that a custom-designed, resource-efficient quantum model can outperform established classical deep learning methods in both performance and efficiency for complex medical image classification. The VQC provides a 3.5-fold gain in parameter efficiency, achieving the highest accuracy of 95% using only 24 trainable parameters. This efficiency is enabled by the novel application of amplitude encoding to the medical images, which compresses 16 features into just 4 qubits. The VQC demonstrates robustness vital for medical diagnostics, achieving a Specificity of 0.983. Its shallow architecture is also NISQ-friendly and remains stable by avoiding the Barren Plateau issue (Gradient Norm: 0.11), validating the path toward quantum advantage in diagnostic tools. The results of this approach highlight the potential amplitude encoding in quantum machine learning, as a feasible and effective method for classifying real-world medical images. This work also opens avenues for future hybrid quantum-classical diagnostic systems that could utilize richer quantum state encodings for significant gains in computational efficiency and accuracy.
Purpose This study investigates the integration of quantum-enhanced machine learning (QML) into medical image analysis, focusing on classification and feature extraction tasks. It aims to evaluate whether hybrid quantum-classical models can overcome the limitations of traditional machine learning in handling high-dimensional, clinically relevant imaging data. Design/methodology/approach Hybrid architectures combining classical preprocessing with quantum components, specifically variational quantum circuits (VQCs) and quantum kernel methods, were developed and implemented in simulated quantum environments using Qiskit and PennyLane on Google Colab. Publicly available datasets (ChestX-ray14, Brain Tumor MRI and CT Hemorrhage) were preprocessed and encoded into quantum states. Model performance was evaluated against classical baselines (MLP and CNN) using accuracy, precision, recall, F1-score, convergence speed and trainable parameters. Findings Quantum-enhanced models achieved competitive or superior performance compared to classical models with significantly fewer trainable parameters and faster convergence. The Quantum Kernel SVM demonstrated the highest precision (89.1%) and F1-score (88.5%) using only 8 parameters, while VQC models converged up to 2× faster than classical baselines. These results highlight the potential of QML to improve efficiency, robustness and scalability in diagnostic imaging workflows, particularly in resource-constrained or data-limited settings. Research limitations/implications The study relies on simulated quantum environments, which do not capture hardware noise or qubit limitations. Future work will extend to real quantum devices, multimodal data integration and interpretability strategies. Practical implications Quantum kernel methods and lightweight VQC architectures enable faster, resource-efficient diagnostic modeling, making them suitable for clinical environments with limited computational capacity or time-sensitive decision-making needs. Social implications Improving the efficiency and accessibility of medical image analysis has the potential to support faster diagnosis and enhance healthcare delivery, particularly in underserved or resource-limited regions. Originality/value This study provides a practical evaluation of hybrid quantum-classical models applied to multiple real medical imaging datasets in a reproducible simulated environment. It offers an early-stage framework demonstrating how QML techniques can be integrated into existing machine learning pipelines for medical image analysis.
Brain tumor detection is a vital and challenging task in medical diagnosis, requiring highly precise and efficient methods to improve patient treatment outcomes. Traditional approaches rely on classical machine learning and deep learning techniques, which, while effective to a degree, often struggle with capturing the complex and high-dimensional patterns present in medical imaging data. A significant limitation of these conventional methods is their inability to process and analyze intricate features efficiently, which can impact diagnostic accuracy. To address these challenges, this work proposes a novel Quantum Convolutional Neural Network (QCNN) framework that combines quantum computing principles, via quantum circuits, with classical machine learning architectures implemented through tools like PyTorch and PennyLane. This hybrid approach enhances feature extraction and classification capabilities, leading to superior performance. Experimental results demonstrate that the QCNN model achieves an improved accuracy of 90 percent on the test dataset, surpassing traditional methods and showing promise for advancing brain tumor detection technology. This improvement is supported by consistent decreases in training and validation loss during model training, highlighting the robustness and efficacy of the quantum-enhanced model.