Our research introduces a state-of-the-art bagging ensemble model that leverages Quantum Support Vector Classifiers (QSVC) to assess the risk of heart disease. Testing involved rigorous experimentation on the Cleveland data set for which QSVC has demonstrated better performance compared with benchmark classifiers and other quantum-inspired models as well, achieving an excellent accuracy of 90.16%. The boosted accuracy shows the competence of quantum machine learning in serving as a potential upgrade of predictive analytics within the healthcare industry. In addition to its impressive performance metrics, the model incorporates SHAP (SHapley Additive exPlanations) analysis, which significantly enhances its interpretability. By identifying and elucidating the utmost need of various features in this entire route, SHAP analysis makes the persons who are into medical practicing get to know more about the core of this model. This transparency is crucial in medical applications, where understanding the factors influencing a diagnosis can lead to better key decisions and sentiments of patients. Thus, Implications of this research extend beyond mere performance statistics. The research shows that quantum machine learning, and specifically QSVC, can revolutionize healthcare by providing interpretable and accurate predictive models. Over time, the technology will keep improving, and ultimately it will improve patient care and the quality of healthcare.
Our research introduces a state-of-the-art bagging ensemble model that leverages Quantum Support Vector Classifiers (QSVC) to assess the risk of heart disease. Testing involved rigorous experimentation on the Cleveland data set for which QSVC has demonstrated better performance compared with benchmark classifiers and other quantum-inspired models as well, achieving an excellent accuracy of 90.16%. The boosted accuracy shows the competence of quantum machine learning in serving as a potential upgrade of predictive analytics within the healthcare industry. In addition to its impressive performance metrics, the model incorporates SHAP (SHapley Additive exPlanations) analysis, which significantly enhances its interpretability. By identifying and elucidating the utmost need of various features in this entire route, SHAP analysis makes the persons who are into medical practicing get to know more about the core of this model. This transparency is crucial in medical applications, where understanding the factors influencing a diagnosis can lead to better key decisions and sentiments of patients. Thus, Implications of this research extend beyond mere performance statistics. The research shows that quantum machine learning, and specifically QSVC, can revolutionize healthcare by providing interpretable and accurate predictive models. Over time, the technology will keep improving, and ultimately it will improve patient care and the quality of healthcare.
Nowadays, quantum machine learning is attracting great interest in a wide range of fields due to its potential superior performance and capabilities. The massive increase in computational capacity and speed of quantum computers can lead to a quantum leap in the healthcare field. Heart disease seriously threatens human health since it is the leading cause of death worldwide. Quantum machine learning methods can propose effective solutions to predict heart disease and aid in early diagnosis. In this study, an ensemble machine learning model based on quantum machine learning classifiers is proposed to predict the risk of heart disease. The proposed model is a bagging ensemble learning model where a quantum support vector classifier was used as a base classifier. Furthermore, in order to make the model’s outcomes more explainable, the importance of every single feature in the prediction is computed and visualized using SHapley Additive exPlanations (SHAP) framework. In the experimental study, other stand-alone quantum classifiers, namely, Quantum Support Vector Classifier (QSVC), Quantum Neural Network (QNN), and Variational Quantum Classifier (VQC) are applied and compared with classical machine learning classifiers such as Support Vector Machine (SVM), and Artificial Neural Network (ANN). The experimental results on the Cleveland dataset reveal the superiority of QSVC compared to the others, which explains its use in the proposed bagging model. The Bagging-QSVC model outperforms all aforementioned classifiers with an accuracy of 90.16% while showing great competitiveness compared to some state-of-the-art models using the same dataset. The results of the study indicate that quantum machine learning classifiers perform better than classical machine learning classifiers in predicting heart disease. In addition, the study reveals that the bagging ensemble learning technique is effective in improving the prediction accuracy of quantum classifiers.
Cardiovascular disease remains one of the leading causes of death worldwide, making early and accurate risk prediction essential. Conventional machine learning models often struggle to handle complex medical data, resulting in limited accuracy and reduced interpretability. To address these challenges, this study presents a hybrid prediction framework that combines Quantum Machine Learning (QML) with ensemble learning techniques. Classical models such as Support Vector Classifier (SVC) and Artificial Neural Network (ANN) are used as baseline approaches. In addition, quantum models including QSVC, Variational Quantum Classifier (VQC), and Quantum Neural Network (QNN) are employed to capture complex non-linear patterns present in clinical data. To further enhance performance, a Bagging-QSVC ensemble model is proposed, improving robustness and overall classification accuracy. Interpretability is incorporated using SHAP, allowing the model’s predictions to be more transparent and easier to understand in a clinical context. Experimental results indicate that the proposed quantum ensemble achieves an accuracy of around 90%, outperforming both classical models and individual quantum models. Furthermore, a real-time user interface is developed, enabling clinicians to input patient data and receive immediate risk predictions. Overall, the system provides a reliable and interpretable solution suitable for practical clinical decision support.
Cardiovascular disease is one of the most common reasons of increases the global death rate, suggesting initial detection and timely treatment crucial. While traditional machine learning models have been effective in predicting heart disease, Quantum Computing (QC) introduces new possibilities for improving accuracy and processing speed. In this regard the application of Quantum Machine Learning (QML) approaches-categorically, Quantum Neural Networks (QNN) and Quantum Support Vector Classification (QSVC)-to predict heart disease using key health indicators such as present-age, levels of cholesterol, Blood Pressure (BP), and lifestyle choices. QNN is utilized to recognize complex patterns in patient data, leveraging deep learning to understand intricate connections between various risk factors. Meanwhile, QSVC takes advantage of QC ability to compute large amounts of information at once, making classification faster and more precise. Both models are trained and tested on a heart disease dataset and compared with traditional machine learning methods to assess their accuracy, efficiency, and scalability. The results show that while quantum and classical models achieve similar accuracy, quantum computing significantly reduces processing time, making it highly efficient for analyzing large datasets. This study highlights the strength of QC in transforming medical diagnostics, offering faster and more reliable predictive models for early heart disease detection. By integrating quantum algorithms into healthcare, this research contributes to the advancement of AI-driven medical solutions, resulting in more efficient and individual patient care.
Early and accurate prediction of cardiovascular disease is essential to improve patient outcomes and reduce healthcare costs. This research presents a hybrid classical–quantum machine learning framework for heart disease prediction using the Cleveland dataset. The proposed pipeline integrates advanced feature engineering, bio-inspired optimization, and quantum-inspired learning to improve classification performance and interpretability. The system applies multiple feature selection techniques followed by a hybrid feature fusion strategy. Orthogonal Component Analysis is then used for dimensionality transformation, while quantum-inspired feature mapping simulates quantum state coding. A feature selection mechanism based on a Genetic Algorithm optimizes the subset of features. Classical and quantum machine learning models are evaluated, including Random Forest, Gradient Boosting, K-Nearest Neighbors, Logistic Regression, Quantum Support Vector Classifier, Variational Quantum Classifier, Quantum KNN, and Quantum Neural Networks. Model performance is evaluated using accuracy metrics. To ensure transparency and trustworthiness, explainable AI techniques such as SHAP, LIME and DiCE are integrated to provide local and global interpretability of predictions. Experimental results demonstrate that the proposed hybrid framework improves predictive performance by achieving 90% accuracy compared to traditional machine learning approaches, while maintaining model explainability. The model achieved an overall accuracy of 90%, indicating strong predictive capability in cardiovascular disease risk classification. A detailed analysis of class-wise performance shows that for Class 0, the model obtained a precision of 0.85, a recall of 0.97, and an F1-score of 0.90, demonstrating excellent ability to correctly identify negative cases with minimal false negatives. For Class 1, the model achieved a precision of 0.96, a recall of 0.84, and an F1-score of 0.90, indicating high confidence in positive predictions, though with slightly lower recall compared to Class 0. This study highlights the potential of combining classical feature engineering, evolutionary optimization and quantum-inspired learning for next-generation medical decision support systems. The integration of quantum-inspired techniques also provides a promising direction for improving computational efficiency and model robustness in healthcare analytics. The findings suggest that hybrid classical–quantum learning approaches can support clinicians in making faster and more reliable diagnostic decisions.
Coronary heart disease (CHD) is a severe cardiac disease, and hence, its early diagnosis is essential as it improves treatment results and saves money on medical care. The prevailing development of quantum computing and machine learning (ML) technologies may bring practical improvement to the performance of CHD diagnosis. Quantum machine learning (QML) is receiving tremendous interest in various disciplines due to its higher performance and capabilities. Techniques for QML have the potential to forecast cardiac disease and help in early detection. To predict the risk of coronary heart disease, a hybrid approach utilising an ensemble machine learning model based on QML classifiers is presented in this paper. Our approach, with its unique ability to address multidimensional healthcare data, reassures the method’s robustness by fusing quantum and classical ML algorithms in a multi-step inferential framework. Reducing cardiac morbidity and mortality requires early detection of heart disease. In this research, a hybrid approach utilises techniques with quantum computing capabilities to tackle complex problems that are not amenable to conventional ML algorithms and to minimise computational expenses. The proposed method has been developed in the Raspberry Pi 4B Graphics Processing Unit (GPU) platform and tested on a broad dataset that integrates clinical and imaging data from patients suffering from CHD and healthy controls. The proposed research is developed with a hybrid approach that combines different machine learning algorithms, such as KNN + RF, DT + RF, LR + RF, and Adaboost + RF, for diagnosing coronary illness with higher accuracy through feature selection. The proposed system performance obtained an accuracy of 99%, utilising 20000 datasets with 14 attributes from various datasets collected from the Local Pathology Lab in the Muzaffarnagar District of Uttar Pradesh, India. Compared to classical machine learning models, the accuracy, sensitivity, F1 score, and specificity of the proposed hybrid QML model used with CHD are manifold higher.
Heart disease continues to be among the top causes of death globally, and thus precise and timely detection mechanisms are necessary for successful clinical intervention. This chapter introduces a sophisticated predictive model integrating quantum-enhanced feature extraction with classical and quantum machine learning (QML) models to enhance prediction accuracy and reliability of heart disease. Quantum models like quantum random forest (QRF), quantum k-nearest neighbor (QKNN), and quantum gradient boosting classifier (QGBC) are used in conjunction with traditional models like XGBoost and SVM to investigate hybrid computational synergies. The method utilizes quantum feature mapping and entanglement-based encoding to identify intricate nonlinear patterns present in cardiovascular data. A thorough performance comparison based on the UCI Heart Disease dataset shows that quantum-augmented models exhibit better predictive accuracy, precision, and F1-scores than conventional models. The findings support the potential of quantum computing to speed up healthcare analytics and make more accurate disease diagnosis possible. This work discusses the pioneering merger of quantum computing and machine learning as a revolutionary strategy for data-driven intelligent medical decision support systems.