Abstract Airline itinerary and scheduling represent some of the most difficult computational problems that exist in transportation. The problems require choosing the best flight routes while determining schedules and allocating resources through various constraints which include regulatory requirements and maintenance schedules and dynamic demand patterns. The solution of small and medium-scale instances has been achieved through mixed-integer programming and heuristic methods including simulated annealing and genetic algorithms and branch-and-price but these methods become impractical for larger real-world instances due to exponential scaling issues. Quantum computing has introduced fresh solutions which enable the resolution of these problems. Quantum mechanical phenomena particularly superposition and entanglement enable optimization algorithms to examine an exponentially expanded solution space simultaneously. Our research applies a basic airline scheduling problem to the Traveling Salesman Problem (TSP) before converting it into a Quadratic Unconstrained Binary Optimization (QUBO) problem. The Quantum Approximate Optimization Algorithm (QAOA) serves as a hybrid quantum-classical method to solve this formulation. The experimental evaluation of a 4-city scenario shows that quantum-based optimization generates performance levels comparable to traditional methods and indicates that improved quantum hardware development will provide computational benefits for complex airline scheduling problems. This research holds dual importance because it can minimize operational expenses and improve scheduling performance and it establishes fundamental principles for complex combinatorial problem optimization across the transportation industry. The research establishes fundamental principles for quantum-enabled applications that will revolutionize airline operations and other transportation networks by solving critical scalability and solution quality problems.
Abstract Airline itinerary and scheduling represent some of the most difficult computational problems that exist in transportation. The problems require choosing the best flight routes while determining schedules and allocating resources through various constraints which include regulatory requirements and maintenance schedules and dynamic demand patterns. The solution of small and medium-scale instances has been achieved through mixed-integer programming and heuristic methods including simulated annealing and genetic algorithms and branch-and-price but these methods become impractical for larger real-world instances due to exponential scaling issues. Quantum computing has introduced fresh solutions which enable the resolution of these problems. Quantum mechanical phenomena particularly superposition and entanglement enable optimization algorithms to examine an exponentially expanded solution space simultaneously. Our research applies a basic airline scheduling problem to the Traveling Salesman Problem (TSP) before converting it into a Quadratic Unconstrained Binary Optimization (QUBO) problem. The Quantum Approximate Optimization Algorithm (QAOA) serves as a hybrid quantum-classical method to solve this formulation. The experimental evaluation of a 4-city scenario shows that quantum-based optimization generates performance levels comparable to traditional methods and indicates that improved quantum hardware development will provide computational benefits for complex airline scheduling problems. This research holds dual importance because it can minimize operational expenses and improve scheduling performance and it establishes fundamental principles for complex combinatorial problem optimization across the transportation industry. The research establishes fundamental principles for quantum-enabled applications that will revolutionize airline operations and other transportation networks by solving critical scalability and solution quality problems.
Airline and space mission scheduling present complex combinatorial optimization challenges, requiring sophisticated coordination of multiple resources under stringent operational constraints. This paper introduces a novel hybrid quantum-classical framework for scheduling optimization, the Quantum Scheduling Optimization Algorithm (QSOA), addressing crew assignment, gate allocation, and trajectory planning through advanced quantum machine learning techniques. We formulate the scheduling problems as stochastic multi-objective optimization and propose three integrated solution approaches: (1) hybrid quantum optimization via QAOA with constraint-aware loss functions and problem decomposition strategies, (2) classical-quantum integration using graph partitioning and variational circuit optimization, and (3) comprehensive baselines including mixed-integer programming, genetic algorithms, and reinforcement learning formulations. For multi-objective handling, we develop Pareto-optimal sampling techniques combining quantum superposition with classical post-processing for constraint repair and solution refinement. Our experimental evaluation on realistic airline crew scheduling benchmarks and space mission simulators demonstrates significant improvements: the hybrid QSOA achieves 19.2\% cost reduction in airline scheduling compared to classical heuristics, while quantum methods provide competitive solutions for moderate-sized space mission subproblems with 15-18\% improvement in multi-objective trade-offs. The framework shows promise for scalable deployment in real-world transportation networks, with practical implications for next-generation scheduling optimization in complex operational environments.
This study explores quantum computing for combinatorial optimization, focusing on the Traveling Salesman Problem (TSP). Using Qiskit, the Quantum Approximate Optimization Algorithm (QAOA) is implemented on simulators and quantum hardware, and compared with classical optimization using Gurobi. TSP instances are encoded as Quadratic Unconstrained Binary Optimization (QUBO) problems derived from the Miller–Tucker–Zemlin formulation, with quadratic penalties enforcing degree and subtour constraints. Results indicate that QAOA consistently generates feasible tours, but classical branch-and-bound methods achieve better solution quality and runtime. On Noisy Intermediate-Scale Quantum (NISQ) devices, performance degrades with problem size due to sensitivity to parameter tuning, penalty scaling, and hardware noise. Among the tested classical optimizers, COBYLA provides the best balance of efficiency and noise tolerance. Overall, this work establishes a reproducible quantum-classical workflow, provides performance baselines, and identifies critical factors such as encoding design, optimizer choice, and error mitigation for improving near-term quantum heuristic performance.
Combinatorial Optimization (CO) is one of the most important areas in the field of optimization, with practical applications found in every industry, including both the private and public sectors. In recent years, it was discovered that a mathematical formulation known as QUBO (Quadratic Unconstrained Binary Optimization) problem can embrace an exceptional variety of important CO problems found in the industry. In this work, we explore the Quantum Approximate Optimization Algorithm (QAOA) as a quantum computing approach to solve the Knapsack Problem efficiently by formulating the problem as a QUBO model. Here we implemented QAOA on a quantum emulator, leveraging quantum superposition and entanglement to explore multiple solutions simultaneously. The method offers a promising route for solving large, complex scheduling and resource allocation problems that are tough for classical algorithms, with potential applications in logistics, HPC resource scheduling, and energy optimization.
The Traveling Salesman Problem (TSP) is a fundamental challenge in combinatorial optimization, widely applied in logistics and transportation. As the size of TSP instances grows, traditional algorithms often struggle to produce high-quality solutions within reasonable timeframes. This study investigates the potential of the Quantum Approximate Optimization Algorithm (QAOA), a hybrid quantum-classical method, to solve TSP under realistic constraints. We adopt a QUBO-based formulation of TSP that integrates real-world logistical constraints reflecting operational conditions, such as vehicle capacity, road accessibility, and time windows, while ensuring compatibility with the limitations of current quantum hardware. Our experiments are conducted in a simulated environment using high-performance computing (HPC) resources to assess QAOA's performance across different problem sizes and quantum circuit depths. In order to improve scalability, we propose clustering QAOA (Cl-QAOA), a hybrid approach combining classical machine learning with QAOA. This method decomposes large TSP instances into smaller sub-problems, making quantum optimization feasible even on devices with a limited number of qubits. The results offer a comprehensive evaluation of QAOA's strengths and limitations in solving constrained TSP scenarios. This study advances quantum optimization and lays groundwork for future large-scale applications.
This thesis explores quantum computing for combinatorial optimization through the Traveling Salesman Problem (TSP), which aims to find a minimum-cost Hamiltonian cycle visiting each city exactly once. Using Qiskit, we implement the Quantum Approximate Optimization Algorithm (QAOA) on both simulators and quantum hardware, and compare its performance with that of classical exact optimization via the Gurobi solver. TSP instances are encoded as Quadratic Unconstrained Binary Optimization (QUBO) problems derived from the Miller–Tucker–Zemlin formulation, with degree and subtour constraints embedded using quadratic penalties. Results indicate that QAOA consistently generates feasible tours, but classical branch-and-bound solvers outperform it in both solution quality and runtime. On Noisy Intermediate-Scale Quantum (NISQ) devices, the optimality gap grows with problem size, reflecting sensitivity to variational parameter tuning, penalty scaling, and hardware noise. Among classical optimizers for QAOA, COBYLA offers the most effective tradeoff between efficiency and noise tolerance. Overall, this work establishes a reproducible quantum-classical workflow, provides performance baselines, and identifies critical factors such as encoding design, optimizer choice, and error mitigation for improving near-term quantum heuristic performance.
The Traveling Salesman Problem (TSP) is a cornerstone of combinatorial optimization with widespread applications in logistics and transportation. As problem sizes increase, classical algorithms often fail to deliver high-quality solutions within practical time constraints. This paper explores the use of the Quantum Approximate Optimization Algorithm (QAOA), a hybrid quantum-classical algorithm, to address TSP instances under realistic conditions. We present a QUBO-based formulation of the TSP that integrates practical constraints reflecting real-world conditions—such as vehicle capacity, road accessibility, and time windows—while maintaining compatibility with limitations of current quantum hardware. Our analysis is conducted in a simulated environment, leveraging high-performance computing (HPC) resources to evaluate the algorithm’s performance across varying problem sizes and circuit depths. This approach enables a comprehensive assessment of QAOA’s capabilities and limitations in solving constrained TSP scenarios, thereby laying the groundwork for its deployment on future large-scale quantum hardware.