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Physics of Particles and Nuclei

Simulations of the Quantum Entangled States Migration Process in Cell Microtubules

S.Eh. Shirmovsky, A. Yu. Chizhov

Published Jun 1, 2024• 3 citations
Publisher

Abstract

Abstract The work simulates the process of migration of quantum entangled states between tryptophans in cell microtubules connected by dipole-dipole interaction, so that microtubules can be considered as a signaling system for transmitting information via the quantum channel. The paper shows that the rate of propagation of entangled states falls within the range of the nerve impulse velocity.

DOI
10.1134/s1063779624030754

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Recent experimental research with marine algae points towards quantum entanglement at ambient temperature, with correlations between essential biological units separated by distances as long as 20 Angströms. The associated decoherence times, due to environmental influences, are found to be of order 400 fs. This prompted some authors to connect such findings with the possibility of some kind of quantum computation taking place in these biological entities: within the decoherence time scales, the cell "quantum calculates" the optimal "path" along which energy and signal would be transported more efficiently. Prompted by these experimental results, in this talk I remind the audience of a related topic proposed several years ago in connection with the possible rôle of quantum mechanics and/or field theory on dissipation-free energy transfer in microtubules (MT), which constitute fundamental cell substructures. The basic assumption was to view the cell MT as quantum electrodynamical cavities, providing sufficient isolation in vivo to enable the formation of electric-dipole quantum coherent solitonic states across the tubulin dimer walls. Crucial to this, were argued to be the electromagnetic interactions of the dipole moments of the tubulin dimers with the dipole quanta in the ordered water interiors of the MT, that play the rôle of quantum coherent cavity modes. Quantum entanglement between tubulin dimers was argued to be possible, provided there exists sufficient isolation from other environmental cell effects. The model was based on certain ferroelectric aspects of MT. Subsequent experiments in vitro could not confirm ferroelectricity at room temperatures, however they provided experimental measurements of the induced electric dipole moments of the MT under the influence of external electric fields. Nevertheless, this does not demonstrate that in vivo MT are not ferroelectric materials. More refined experiments should be done. In the talk I review the model and the associated experimental tests so far and discuss future directions, especially in view of the algae photo-experiments.

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Abstract The work simulates the process of migration of quantum entangled states between tryptophans in cell microtubules connected by dipole-dipole interaction, so that microtubules can be considered as a signaling system for transmitting information via the quantum channel. The paper shows that the rate of propagation of entangled states falls within the range of the nerve impulse velocity.
Recent experimental research with marine algae points towards quantum entanglement at ambient temperature, with correlations between essential biological units separated by distances as long as 20 Angströms. The associated decoherence times, due to environmental influences, are found to be of order 400 fs. This prompted some authors to connect such findings with the possibility of some kind of quantum computation taking place in these biological entities: within the decoherence time scales, the cell "quantum calculates" the optimal "path" along which energy and signal would be transported more efficiently. Prompted by these experimental results, in this talk I remind the audience of a related topic proposed several years ago in connection with the possible rôle of quantum mechanics and/or field theory on dissipation-free energy transfer in microtubules (MT), which constitute fundamental cell substructures. The basic assumption was to view the cell MT as quantum electrodynamical cavities, providing sufficient isolation in vivo to enable the formation of electric-dipole quantum coherent solitonic states across the tubulin dimer walls. Crucial to this, were argued to be the electromagnetic interactions of the dipole moments of the tubulin dimers with the dipole quanta in the ordered water interiors of the MT, that play the rôle of quantum coherent cavity modes. Quantum entanglement between tubulin dimers was argued to be possible, provided there exists sufficient isolation from other environmental cell effects. The model was based on certain ferroelectric aspects of MT. Subsequent experiments in vitro could not confirm ferroelectricity at room temperatures, however they provided experimental measurements of the induced electric dipole moments of the MT under the influence of external electric fields. Nevertheless, this does not demonstrate that in vivo MT are not ferroelectric materials. More refined experiments should be done. In the talk I review the model and the associated experimental tests so far and discuss future directions, especially in view of the algae photo-experiments.
Prompted by recent experimental results in marine algae, indicating quantum entanglement at ambient temperature, with correlations between essential biological units separated by distances as long as 20 Angstroms and decoherence times, due to environmental influences, of order 400 fs, I review here a related topic proposed several years ago in connection with the possible rôle of quantum mechanics and/or field theory on dissipation-free energy transfer in (brain) microtubules (MT). The basic assumption was to view the cell MT as quantum electrodynamical cavities, providing sufficient isolation in vivo to enable the formation of electric-dipole quantum coherent solitonic states across the tubulin dimer walls. Crucial to this, were argued to be the electromagnetic interactions of the dipole moments of the tubulin dimers with the dipole quanta in the ordered water interiors of the MT, that play the rôle of quantum coherent cavity modes. Quantum entanglement between tubulin dimers was argued to be possible, provided there exists sufficient isolation from other environmental cell effects. Thus, decoherence times as long as 10 −7 −10 −6 s could characterise the MT systems. The model was based on certain ferroelectric aspects of MT. In the talk I revisit these decoherence time scales in light of the algae measurements and argue that, even if the environmental decoherence implies short time scales of order of a few hundreds of fs, this is a sufficient time for some kind of quantum computation to take place in (brain) MT, so that within these time scales the cell "quantum calculates" the optimal "path" along which energy and signal (information) are transported most efficiently along the MT.
This paper aims to address the possibility of parametric resonance effects in microtubules via tryptophan qubits, using the Hamiltonian of the cavity quantum electrodynamics (QED) model involving photons in a waveguide and the surrounding environment. The time evolution equations for qubits and photons are derived using the input–output formulation. Input signals with a 560 nm wavelength are amplified by Rabi oscillations for tryptophan qubits in excited states. Here, the qubits organized in multiple layers are all in excited states. When an appropriate decay to the environment occurs as internal loss, which is prepared in multiple layers, we find binary patterns of the parametric amplification of input signals and the reduction of output signals. This property might help us to understand the information processing of optical signals by filtering them with the use of tryptophan residues in microtubules and diffused nonlocal processing spreading over the whole brain in the form of holograms.
In this paper, we introduce waveguide Quantum Electrodynamics (wQED) for the description of tryptophans in microtubules representing data qubits for information storage and, possibly, information processing. We propose a Hamiltonian in wQED and derive Heisenberg equations for qubits and photons. Using the Heisenberg equations, we derive time-evolution equations for the probability of qubits and the distribution of photons both at zero and finite temperature. We then demonstrate the resultant sub-radiance with small decay rates, which is required to achieve robust data qubits for information storage by coupling tryptophan residues containing data qubits with water molecules as Josephson quantum filters (JQFs). We also describe an oscillation processes of qubits in a tubulin dimer through the propagation of excitations with changing decay rates of JQFs. Data qubits are found to retain initial values by adopting sub-radiant states involving entanglement with water degrees of freedom.
Abstract This paper provides a model of how tryptophan and water qubit states in neuronal microtubules can be manipulated by external photon supply. The formalism employed is cavity quantum electrodynamics represented by Tavis–Cummings Hamiltonian with the degrees of freedom that include upper polariton, lower polariton (LP) states and dark states, coupled with photons in a waveguide and the environment. Time-evolution equations for tryptophan and water qubits and photons are derived. Within this framework, a possible phase-modulation mechanism relevant to holographic information processing is proposed and described. External photon supply at frequencies corresponding to LP states might induce dynamical evolution in tryptophan and water qubits, suggesting a possible phase-modulation mechanism relevant to holographic information processing.
Microtubules,one of the primary components and function units in cytoskeleton system,are filled with water.Due to the interactions between the electronic dipole field of water molecules confined within microtubule and the quantized electromagnetic radiation field,the incoherent,thermal and disordered molecular movement excited the water molecules from ground state to excited state and transferred into the collective coherent radiation.Water is a kerr medium which contains non-linear effect.When propagating in it,the coherent state we concerned in this paper can evolve into quantum superposition states.