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Optical and Quantum Sensing and Precision Metrology

Quantum x-ray imaging for medical and industrial applications

Brian D. Yanoff, S. Shwartz, Eliahu Cohen, V.B. Neculaes, Uwe Wiedmann, Jonathan R. Owens, Loucas Tsakalakos

Published Mar 4, 2021• 1 citation
Publisher

Abstract

We provide an introductory overview of medical and industrial x-ray imaging applications and requirements for readers whose primary background is in quantum imaging. We discuss some opportunities for quantum X-ray imaging and related techniques such as ghost imaging to provide meaningful benefits in imaging and explain some of the key challenges that remain before practical applications can reach end users.

DOI
10.1117/12.2586972

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Abstract Quantum imaging is a multifaceted field of research that promises highly efficient imaging in extreme spectral ranges as well as ultralow‐light microscopy. Since the first proof‐of‐concept experiments over 30 years ago, the field has evolved from highly fascinating academic research to the verge of demonstrating practical technological enhancements in imaging and microscopy. Here, the aim is to give researchers from outside the quantum optical community, in particular those applying imaging technology, an overview of several promising quantum imaging approaches and evaluate both the quantum benefit and the prospects for practical usage in the near future. Several use case scenarios are discussed and a careful analysis of related technology requirements and necessary developments toward practical and commercial application is provided.
Quantum imaging is emerging as a transformative approach for biomedical applications, applying nonclassical properties of light, such as entanglement, squeezing, and quantum correlations, to overcome fundamental limits of conventional techniques. These methods promise superior spatial resolution, enhanced signal-to-noise ratios, improved phase sensitivity, and reduced radiation dose, for potentially safer and more precise imaging for delicate biological samples. Here, we present an overview of quantum optical biomedical imaging technologies as well as quantum-inspired imaging methods, including quantum optical coherence tomography, quantum optical microscopy, ghost imaging, multi-parameter quantum imaging, and imaging with quantum-grade cameras. We describe the operating principles, biomedical applications, and unique advantages of each approach, along with the specific challenges for their translation into real-life practice. This review aims to guide future research toward advancing quantum imaging from experimental demonstrations to impactful biomedical tools.
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