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Quantum enhanced imaging and sensing with correlated light

Nigam Samantaray

Published Jan 1, 2017• 1 citation
OpenAlex

Abstract

Without light, there would be no sight. Light acts as a probe in various measurement techniques ranging from imaging to spectroscopy, from small scale cantilever displace- ment measurement in atomic force microscopy to large scale mirror motion in interfer- ometry, light detection and ranging (LIDAR) and many other fields. As the light probe intensity rises, it not only allows reducing the background noise effect, but it also aids precision to the measurement by reducing the photon noise (shot-noise) contribution. However, increasing intensity beyond certain threshold level is not always advantageous for ultra sensitive measurements. For example in the detection of gravitational waves, the current power circulating in the large scale interferometers can not be increased further without introducing other noise sources like thermal effects on the mirrors, un- wanted scattered photons, and back action due to radiation pressure. In the imaging of delicate photo sensitive sample, high power can causes cell damage or it may lead to disturb the regular process under investigation, viz. favouring certain biochemical reaction, which do not correspond to natural in vitro behaviour. At low intensity, pho- ton noise is an important concern and quantum states of light with correlated photon fluctuation can ideally represent a fruitful way to build specific measurement strategies to surpass the limitation of standard approach based on classical light sources, offering an avenue of solutions for ultra sensitive measurements. This thesis work focuses on two application of quantum enhanced measurement strate- gies. The first part of the thesis work has been dedicated to the realization of the first wide-field microscope with Sub Shot Noise (SSN) sensitivity. This is based on the ex- ploitation of quantum correlations in the Squeezed Vacuum state. In the second part, the investigations have made on the role of the quantum correlated beams in an unusual interferometric scheme, in which two identical optical interferometers are subject to the same phase fluctuation. The scheme, in the classical regime, has been already imple- mented in a large scale experiment devoted to the search of possible quantum gravity (QG) effects at Fermilab.

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Without light, there would be no sight. Light acts as a probe in various measurement techniques ranging from imaging to spectroscopy, from small scale cantilever displace- ment measurement in atomic force microscopy to large scale mirror motion in interfer- ometry, light detection and ranging (LIDAR) and many other fields. As the light probe intensity rises, it not only allows reducing the background noise effect, but it also aids precision to the measurement by reducing the photon noise (shot-noise) contribution. However, increasing intensity beyond certain threshold level is not always advantageous for ultra sensitive measurements. For example in the detection of gravitational waves, the current power circulating in the large scale interferometers can not be increased further without introducing other noise sources like thermal effects on the mirrors, un- wanted scattered photons, and back action due to radiation pressure. In the imaging of delicate photo sensitive sample, high power can causes cell damage or it may lead to disturb the regular process under investigation, viz. favouring certain biochemical reaction, which do not correspond to natural in vitro behaviour. At low intensity, pho- ton noise is an important concern and quantum states of light with correlated photon fluctuation can ideally represent a fruitful way to build specific measurement strategies to surpass the limitation of standard approach based on classical light sources, offering an avenue of solutions for ultra sensitive measurements. This thesis work focuses on two application of quantum enhanced measurement strate- gies. The first part of the thesis work has been dedicated to the realization of the first wide-field microscope with Sub Shot Noise (SSN) sensitivity. This is based on the ex- ploitation of quantum correlations in the Squeezed Vacuum state. In the second part, the investigations have made on the role of the quantum correlated beams in an unusual interferometric scheme, in which two identical optical interferometers are subject to the same phase fluctuation. The scheme, in the classical regime, has been already imple- mented in a large scale experiment devoted to the search of possible quantum gravity (QG) effects at Fermilab.
Quantum fluctuations in the phase and amplitude quadratures of light set limitations on the sensitivity of modern optical instruments. The sensitivity of the interferometric gravitational-wave detectors, such as the Advanced Laser Interferometer Gravitational-Wave Observatory (LIGO), is limited by quantum shot noise, quantum radiation pressure noise, and a set of classical noises. We show how the quantum properties of light can be used to distinguish these noises using correlation techniques. Particularly, in the first part of the paper we show estimations of the coating thermal noise and gas phase noise, hidden below the quantum shot noise in the Advanced LIGO sensitivity curve. We also make projections on the observatory sensitivity during the next science runs. In the second part of the paper we discuss the correlation technique that reveals the quantum radiation pressure noise from the background of classical noises and shot noise. We apply this technique to the Advanced LIGO data, collected during the first science run, and experimentally estimate the quantum correlations and quantum radiation pressure noise in the interferometer.
The first detections of gravitational waves have opened an exciting new field of astronomy. One of the most fundamental limitations for the sensitivity of current and future interferometric gravitational-wave detectors is imposed by the quantum nature of light: Quantum vacuum fluctuations entering the interferometer through the readout port will contribute to the detection noise, at high frequencies in the form of shot noise and at low frequencies by radiation pressure noise. A promising way to reduce this quantum noise is the injection of squeezed states of light that have a lower uncertainty in one quadrature than the vacuum state. The GEO 600 gravitational-wave detector demonstrated the use of squeezed light in 2010 and it is now the first detector to routinely apply squeezing to improve its sensitivity beyond the limits set by classical quantum shot noise. This thesis details the practical aspects of long-term stable and efficient squeezed-light integration in a large-scale gravitational-wave detector. Imperfections that can limit the amount of observable non-classical noise improvement, such as optical losses and phase fluctuations, were studied in detail and methods for their mitigation were developed. Novel control schemes for the active stabilisation of the squeezed light field's phase and alignment were one main focus of the investigations. At the same time, important experience was gathered in the operation of the squeezed light source over long timescales. Over the course of the thesis work, improvements were implemented that significantly increased the performance of the squeezed-light application. Squeezing was injected with an overall duty cycle of 88%, reaching a noise reduction of up to 4.4 dB, corresponding to a 40% lowered shot-noise level. This work has firmly established the practical application of squeezing as a mature technology. The gained knowledge will directly inform the implementation of squeezed light for all future gravitational-wave detectors.
This thesis reports the development of a quantum enhanced microparticle tracking technique, which applied to measurements within living cells, allowed the first demonstrations of both biological measurements beyond the quantum noise limit and quantum enhanced spatial resolution within biology. The sensitivity of any optical measurement is limited by noise which follows from quantization of the electromagnetic field. This thesis theoretically characterizes the resulting quantum limit on particle tracking precision; both in the limit of perfect measurements and for the measurements used in real experiments, and theoretically establishes an experimental strategy which could allow the quantum limit to be surpassed via the application of non-classical light. Further, a computational tool is developed which allows rapid characterization of particle tracking experiments, thus providing researchers the benefit of rigorous theoretical predictions without requiring detailed calculations. Following this, classical technologies are developed which can improve microparticle tracking sensitivity and which are enabling steps toward integration of non-classical light. An interferometric strategy is described whereby signal-to-noise is improved by removing unwanted light from the detector. An optical lock-in technique is developed which eliminates low-frequency noise, thus allowing quantum noise limited performance at low frequencies. This is a crucial requirement for quantum enhanced measurements, and can also improve precision in classical experiments. Dark-field illumination is also explored as a method to remove unwanted background light, and the optimal illumination angle is calculated for our intended experiments. These advances are then applied in the development of the first quantum enhanced particle tracking apparatus. Squeezed states of light are used to improve particle tracking precision by 2.7 dB, demonstrating quantum enhanced microscopy for the first time. This was applied to perform the first measurements of living systems with quantum enhanced precision. Naturally occurring lipid particles were tracked within the cytoplasm of Saccharomyces cerevisiae yeast cells, with squeezed light enhancing precision by 2.4 dB. The thermal motion of these particles could then be analyzed to infer the viscosity and elasticity of the local environment, with squeezed light allowing 64% faster observations, thus improving the sensitivity to dynamic biological changes. This experiment was then extended to spatially resolved quantum imaging, with lipid particles used as scanning probes in a technique called photonic force microscopy. The particles sample variations in the local environment with resolution limited by measurement precision rather than the diffraction limit. The use of squeezed light was found to enhance spatial resolution by 14% at an absolute resolution level of 10 nm, comparable to leading classical experiments. This was the first demonstration of both sub-diffraction limited resolution and quantum enhanced resolution in biology, and places practical applications of quantum imaging within reach. Finally, the future challenges and prospects of quantum enhanced particle tracking are outlined.n
In optical microscopy, as in any biological measurement performed with light, there is a compromise between increasing power to improve resolution and decreasing power to prevent photodamage to the biological structure. Quantum optics allows this compromise to be overcome, enabling improved precision without increased illumination intensity. This thesis demonstrates, for the first time, absolute quantum advantage in microscopy, with a specific focus on Stimulated Raman Scattering (SRS) microscopy.SRS microscopy is a powerful tool widely used in many fields, especially in biomedical sciences. It uses a two-photon process where the light is downshifted in frequency by being absorbed and subsequently inelastically scattered by the intrinsic molecular vibrations in the sample. Each element or molecule has a different response, allowing selective imaging of biological systems. SRS microscopy is particularly useful because it is label-free (no addition of dyes, beads or any implanted tracer), meaning that imaging contrast is achieved without modification of, or interference with, the specimen. Here I present our newly built state-of-the-art shot-noise limited SRS microscope. I also characterize the Raman microscope, describe the developped imaging system and show SRS spectroscopy and imaging of both polystyrene beads and living yeast cells.The quantisation of light introduces a fundamental uncertainty, or quantum noise, in both the amplitude and phase quadratures of an optical field. A squeezed state of light is a state of the optical field where the uncertainty of one of these quadratures is reduced below the quantum noise. Therefore, it provides an approach to reduce the noise level below this quantum noise limit and consequently increases measured signal-to-noise ratio. Here I describe the concepts involved in this technique and present our newly built light squeezer. I characterize the squeezing and show up to -1.3 dB of noise floor reduction for a 6 picosecond pulsed laser, which is the pulse duration that maximises the Raman interaction.In this thesis we apply squeezed states of light in SRS, developping a quantum-enhanced micro- scope. Our SRS Raman intensity noise is ∆I/I ≈ 10^(−7) and the measured quantum efficiency of the built photodiode is η = 72%. In this proof of principle we show a reduction of the noise floor of at least 13% below the quantum noise limit for Raman imaging of polystyrene beads and living yeast cells. This enhancement allowed us to resolve the cell membrane where with conventional microscope would be unresolvable. It also allowed sub-micron spatial resolution. The improved image contrast and reduced imaging time, while avoiding photodamage in the sample, surpasses the current state-of-the-art Raman microscopes and opens opportunities for new discoveries in biophysics.
Quantum enhanced optical measurement protocols aim at reducing the uncertainty in the estimation of some physical quantities of a system below the shot-noise limit, classically unavoidable. In particular when small number of photons is used the shot noise can be the main source of uncertainty, in these cases the use of quantum light is of great interest. Note that there are several situations where the number of photons in the probe can not be increased arbitrarily, as when fragile biological samples are under investigation. Two different imaging protocols are discussed in the following.
We analyze in detail a system of two interferometers aimed at the detection of extremely faint phase fluctuations. The idea behind is that a correlated phase-signal like the one predicted by some phenomenological theory of Quantum Gravity (QG) could emerge by correlating the output ports of the interferometers, even when in the single interferometer it confounds with the background. We demonstrated that injecting quantum light in the free ports of the interferometers can reduce the photon noise of the system beyond the shot-noise, enhancing the resolution in the phase-correlation estimation. Our results confirm the benefit of using squeezed beams together with strong coherent beams in interferometry, even in this correlated case. On the other hand, our results concerning the possible use of photon number entanglement in twin beam state pave the way to interesting and probably unexplored areas of application of bipartite entanglement and, in particular, the possibility of reaching surprising uncertainty reduction exploiting new interferometric configurations, as in the case of the system described here.