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Homeopathy

Treating Leick with like: response to criticisms of the use of entanglement to illustrate homeopathy

Lionel R. Milgrom

Published Apr 1, 2008• 14 citations
Publisher

Abstract

In criticising papers which recently appeared in Homeopathy, Leick claims that no double blind randomised clinical trials (DBRCTs) show that homeopathy is efficacious, and that specific effects of substances diluted beyond Avogadro's limit are implausible. He states that generalised entanglement models should be able to improve the design of experiments to test ultra-high dilutions, and disparages the authors' understandings of quantum physics. The paper responds to those criticisms. Several DBRCTs have shown that homeopathy has effects which are not due to placebo and these are now supported by preclinical work. This area of theory is in its infancy and it is unreasonable to expect it to have generated experiments at this stage. The authors have used accepted interpretations of quantum theory: Leick's view is coloured by skepticism concerning homeopathy.

DOI
10.1016/j.homp.2008.02.002

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Annals of Improbable Research•Jan 1, 1999•1 citation
In criticising papers which recently appeared in Homeopathy, Leick claims that no double blind randomised clinical trials (DBRCTs) show that homeopathy is efficacious, and that specific effects of substances diluted beyond Avogadro's limit are implausible. He states that generalised entanglement models should be able to improve the design of experiments to test ultra-high dilutions, and disparages the authors' understandings of quantum physics. The paper responds to those criticisms. Several DBRCTs have shown that homeopathy has effects which are not due to placebo and these are now supported by preclinical work. This area of theory is in its infancy and it is unreasonable to expect it to have generated experiments at this stage. The authors have used accepted interpretations of quantum theory: Leick's view is coloured by skepticism concerning homeopathy.
INTRODUCTION: In two recent studies of double-blind placebo-controlled homeopathic provings, entanglement was reported to have occurred between verum and placebo arms of the trials. This contrasts directly with the entanglement-disrupting effects of blinding, recently proposed as the reason for the failure of randomized controlled trials (RCTs) to demonstrate unequivocally the efficacy of homeopathy. It is proposed here that such entanglement between remedy and placebo during these double-blind placebo controlled provings is the direct result of the blinding process. METHOD: A previously developed theoretical model of entanglement in homeopathy among patient, practitioner, and remedy (called PPR entanglement) was used in this investigation. RESULTS: In agreement with the results from the proving studies, the model predicts that application of the double-blind RCT methodology to homeopathic provings leads to entanglement between both remedy and placebo arms of the trial. CONCLUSIONS: These theoretical findings can be understood in terms of the act of blinding leading to loss of information because of quantum-like state superposition of the verum and placebo proving groups. This is compared to conclusions drawn from the well-known double-slit experiment of quantum physics, and quantum information processing. It leads to a suggestion for testing entanglement in homeopathic provings.
In previous articles, a description of 'unconventional' experiments (e.g. in vitro or clinical studies based on high dilutions, 'memory of water' or homeopathy) using quantum-like probability was proposed. Because the mathematical formulations of quantum logic are frequently an obstacle for physicians and biologists, a modified modeling that rests on classical probability is described in the present article. This modeling is inspired from a relational interpretation of quantum physics that applies not only to microscopic objects, but also to macroscopic structures, including experimental devices and observers. In this framework, any outcome of an experiment is not an absolute property of the observed system as usually considered but is expressed relatively to an observer. A team of interacting observers is thus described from an external view point based on two principles: the outcomes of experiments are expressed relatively to each observer and the observers agree on outcomes when they interact with each other. If probability fluctuations are also taken into account, correlations between 'expected' and observed outcomes emerge. Moreover, quantum-like correlations are predicted in experiments with local blind design but not with centralized blind design. No assumption on 'memory' or other physical modification of water is necessary in the present description although such hypotheses cannot be formally discarded.In conclusion, a simple modeling of 'unconventional' experiments based on classical probability is now available and its predictions can be tested. The underlying concepts are sufficiently intuitive to be spread into the homeopathy community and beyond. It is hoped that this modeling will encourage new studies with optimized designs for in vitro experiments and clinical trials.
Homeopathy is scientifically banned, both for lack of consistent empirical findings, but more so for lack of a sound theoretical model to explain its purported effects. This paper makes an attempt to introduce an explanatory idea based on a generalized version of quantum mechanics (QM), the weak quantum theory (WQT). WQT uses the algebraic formalism of QM proper, but drops some restrictions and definitions typical for QM. This results in a general axiomatic framework similar to QM, but more generalized and applicable to all possible systems. Most notably, WQT predicts entanglement, which in QM is known as Einstein-Podolsky-Rosen (EPR) correlatedness within quantum systems. According to WQT, this entanglement is not only tied to quantum systems, but is to be expected whenever a global and a local variable describing a system are complementary. This idea is used here to reconstruct homeopathy as an exemplification of generalized entanglement as predicted by WQT. It transpires that homeopathy uses two instances of generalized entanglement: one between the remedy and the original substance (potentiation principle) and one between the individual symptoms of a patient and the general symptoms of a remedy picture (similarity principle). By bringing these two elements together, double entanglement ensues, which is reminiscent of cryptographic and teleportation applications of entanglement in QM proper. Homeopathy could be a macroscopic analogue to quantum teleportation. This model is exemplified and some predictions are derived, which make it possible to test the model.
The assertion that 'local' theories of homeopathy are traditional appears to be contradicted by Hahnemann's description of the action of homeopathic medicines as 'spirit-like'. Entanglement theory prohibits the use of entangled states to convey information. Experimental proof of entanglement can only come indirectly. The implications for clinical research include that positive results will probably be found only in large series and that studies should avoid imposing a causal framework.
The possibility of classifying and unifying some of the recent entanglement models for homeopathy is discussed. Unification involves combining the previous GHZ/WQT-based entanglement model, itself a fusion of Greenberger-Horne-Zeilinger (GHZ) three-particle entanglement and a generalised version of quantum theory, called Weak Quantum Theory (WQT), with Walach's semiotic model involving double entanglement. The new combined model invokes a 'geometry' of patient-practitioner-remedy (PPR) entanglement embedded in a therapeutic state space.