Statistical analysis of data from single molecule experiment
Tomasz Burzykowski, Jacek Piotr Szubiakowski, Tobias Rydèn
The maximum-likelihood estimation method is considered. It is based on three-level Dehmelt scheme of isolated quantum system and it makes use of the theory of Markov-modulated Poison process. This method is applied to the analysis of the photon-counting distribution resulting from a single molecule fluorescence experiment. It is assumed that the data available for the estimation contain only the number of collected photons per time interval.
Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE•Nov 18, 2003•4 citations