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International Journal of Nanomedicine

Molecular buffer using a PANDA ring resonator for drug delivery use

Preecha P. Yupapin, Preecha P. Yupapin, Nathaporn Suwanpayak, Ma, Aziz, Ali -

Published Mar 1, 2011• 22 citations
Publisher

Abstract

A novel design of molecular buffer for molecule storage and delivery using a PANDA ring resonator is proposed. The optical vortices can be generated and controlled to form the trapping tools in the same way as the optical tweezers. In theory, the trapping force is formed by the combination between the gradient field and scattering photons, which is reviewed. By using the intense optical vortices generated within the PANDA ring resonator, the required molecules can be trapped and moved (transported) dynamically within the wavelength router or network, ie, a molecular buffer. This can be performed within the wavelength router before reaching the required destination. The advantage of the proposed system is that a transmitter and receiver can be formed within the same system, which is available for molecule storage and transportation.

DOI
10.2147/ijn.s17772

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Advanced materials research•Jun 24, 2014•0 citations
A novel design of molecular buffer for molecule storage and delivery using a PANDA ring resonator is proposed. The optical vortices can be generated and controlled to form the trapping tools in the same way as the optical tweezers. In theory, the trapping force is formed by the combination between the gradient field and scattering photons, which is reviewed. By using the intense optical vortices generated within the PANDA ring resonator, the required molecules can be trapped and moved (transported) dynamically within the wavelength router or network, ie, a molecular buffer. This can be performed within the wavelength router before reaching the required destination. The advantage of the proposed system is that a transmitter and receiver can be formed within the same system, which is available for molecule storage and transportation.
A novel design of molecular buffer for molecule storage and delivery using a PANDA ring resonator is proposed. The optical vortices can be generated and controlled to form the trapping tools in the same way as the optical tweezers. In theory, the trapping force is formed by the combination between the gradient field and scattering photons, which is reviewed. By using the intense optical vortices generated within the PANDA ring resonator, the required molecules can be trapped and moved (transported) dynamically within the wavelength router or network, in which the molecular buffer can be performed within the wavelength router before reaching the required destination. The advantage of the proposed system is that a transmitter and receiver can be formed within the same system, which is available for molecule storage and transportation. Relevant patents are also reviewed in this manuscript. Keywords: Molecular buffer, molecular memory, molecular transceiver, molecular repeater, Optical Router, PANDA Ring Resonator, optical tweezers, tweezer amplification, trapping forces, light polarization state
Optical buffer is recognized as an essential component in a wavelength router, in which packets of data can be stored for resolving packet contention problem and also to delay the outgoing packets [1-2]. In practice, optical router patents have been proposed and recorded [3-5], which can be useful for various applications. Recently, promising techniques of microscopic volume trapping and transportation within an add/drop multiplexer have been reported in both theory [6]and experiment [7], respectively. The transporter in these techniques is known as an optical tweezer. The technique for generating optical tweezers has become a powerful tool for manipulating of micrometer-sized particles. Useful static tweezers have now been well recognized and realized. The use of dynamic tweezers has also been realized in practical works [8-10]. Schulz et al. [11] have shown that trapped atoms between can be transported between two optical potentials. Optical tweezers use forces exerted by intensity gradients in strongly focused beams of light to trap and move nanoscopic volumes of matter. During the movement, another combination of forces is induced between photons due to their interactions caused by photon scattering effects. The field intensity can also be adjusted and tuned to the desired gradient field and scattering force so that the suitable trapping force can be formed. Thus, by configuring the appropriated force for the transmitter/ receiver part, nanoscopic particles can be transported over a long distance. In this chapter, the methods for generating the dynamic optical tweezers/vortices using a dark soliton, a bright soliton and a Gaussian pulse propagating within an add/drop optical multiplexer with two nanoring resonators (PANDA ring resonator) will be discussed. The dynamic behaviors of a soliton and Gaussian pulses are well described. [12]. By using the proposed system, the transceiver can be integrated to form a single device. The transceiver can be used to transport nanoscopic volumes of matter [13], especially, molecules in liquid core waveguide [14, 15], drugs, and DNA, where a buffer is needed before the substance reaches its destination.
A novel design of Molecular Transistor using a microring resonator called a PANDA microring resonator is proposed. A molecular transistor can control its output in proportion to the input signal; that is, it can act as an amplifier. Alternatively, it can be used to turn current on or off in a circuit as an electrically controlled switch. By using the optic tweezers, the trapped molecule can be used to form in the same way of photonic transistor, in which the increasing in magnitude of force can increase the trapped molecules. The trapping probe can be adjusted to fit for the molecules size of 10 nm to 15 nm by control ring's parameters. The molecules can be transport at the through port and storage at the drop port. In application, the number of molecules can be controlled to perform the constant and amplification characteristics, which will be suitable for molecular transistor performance.
An optical thin film battery is a good candidate for such a device [5]. However, the requirement of a nanobattery is that it should have a construction technique that is reliable. Recently, Suwanpayak et al. [24] reported the use of a PANDA ring resonator for drug trapping and delivery applications. In this device, the photons/atoms/ molecules can be trapped and moved within an optical router. In this chapter, we will present the use of a trapping tool for moving atoms/ molecules for their delivery and collection within a thin film grating, where finally, the wavelength-selected tweezers will be formed. An atom assembly within the desired thin film grating can be made by using a PANDA microring resonator. The design for a thin film grating and the simulation result for it have been discussed in this chapter.
A generation of optical capsules and tweezers within a modified optical add-drop filter known as PANDA ring resonator with a new concept is proposed. By using dark and bright solitons, the orthogonal tweezers can be formed within the system and observed simultaneously at the output ports. Under the resonant condition, the optical capsules and tweezers generated by dark and bright soliton pair corresponding to the left-hand and right-hand rotating solitons (tweezers) can be generated. When a soliton is interacted by an object, an angular momentum of either bright or dark tweezers is imparted to the object, in which two possible spin states known as tweezer spins are exhibited. Furthermore, an array of molecular capsules and spins, i.e., trapped molecules can be generated and detected by using the proposed system, which can be used to form large scale tweezer or capsule spins. In application, the trapped molecules can be moved and rotated securely to the required destinations, which can be useful for many applications, especially, in medical diagnosis, therapy and surgery.
We propose a new system of the multi-quantum tweezers array generation using a soliton generation control within the triple ring resonator system, whereas the dynamic tweezers can be generated within a microring device. By using the quantum processor, the entangle photon states of the tweezers can be formed, which is allowed to form the molecular quantum transmission. We have also theoretically shown that the optical tweezers can be controlled and tuned by varying the couple coefficient (κ) between 0.25 and 0.9, with ring resonator radii between 7 and 15 μm, which is available for molecule trapping. In application, the transmission of tweezers with different molecules or DNA can be performed, which is available for high density and security molecular transportation via the optical communication system.