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arXiv:2610.13038 · IEEE Access

Error Mitigation by Zero-Noise Extrapolation (ZNE) in Indirect-Control System

Arijit Das, Masaki Owari

quant-phSubmitted Oct 9, 2026• Announced Oct 12, 2026• 0 citations
arXivHTMLPDF

Abstract

The indirect-control paradigm offers a scalable approach to quantum computation by restricting external operations to a small subset of qubits, whereas the entire system evolves under its intrinsic many-body Hamiltonian. This framework reduces hardware complexity and limits the noise introduced through control channels. Recently, Anan et al. proposed an implementation of the variational quantum eigensolver (VQE) within this indirect-control architecture. However, the impact and integration of quantum error mitigation techniques in such a setting remain largely unexplored. In particular, zero-noise extrapolation (ZNE), a widely used error mitigation strategy, has not yet been systematically adapted to indirect-control VQE. A key requirement of ZNE is the controlled amplification of noise, which is commonly achieved through circuit-level techniques such as unitary folding. In the indirect-control framework, however, quantum operations are largely governed by continuous time-evolution under the system Hamiltonian, making the construction of physically realizable inverse operations non-trivial. In this study, we investigate the feasibility of implementing ZNE within the indirect-controlVQEframework.We address the challenges associated with unitary folding in the presence of time-evolution operators and, with a minimal relaxation of the indirect-control constraint, we propose a ZNE-based error-mitigation strategy that exploits the symmetry of the one-dimensional XY spin chain.

DOI
10.1109/ACCESS.2026.3741203
Comments
28 pages, 21 figures, 5 tables. Accepted for publication in IEEE Access

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The indirect-control paradigm offers a scalable approach to quantum computation by restricting external operations to a small subset of qubits, whereas the entire system evolves under its intrinsic many-body Hamiltonian. This framework reduces hardware complexity and limits the noise introduced through control channels. Recently, Anan et al. proposed an implementation of the variational quantum eigensolver (VQE) within this indirect-control architecture. However, the impact and integration of quantum error mitigation techniques in such a setting remain largely unexplored. In particular, zero-noise extrapolation (ZNE), a widely used error mitigation strategy, has not yet been systematically adapted to indirect-control VQE. A key requirement of ZNE is the controlled amplification of noise, which is commonly achieved through circuit-level techniques such as unitary folding. In the indirect-control framework, however, quantum operations are largely governed by continuous time-evolution under the system Hamiltonian, making the construction of physically realizable inverse operations non-trivial. In this study, we investigate the feasibility of implementing ZNE within the indirect-controlVQEframework.We address the challenges associated with unitary folding in the presence of time-evolution operators and, with a minimal relaxation of the indirect-control constraint, we propose a ZNE-based error-mitigation strategy that exploits the symmetry of the one-dimensional XY spin chain.
Zero-noise extrapolation (ZNE) is an increasingly popular technique for mitigating errors in noisy quantum computations without using additional quantum resources. We review the fundamentals of ZNE and propose several improvements to noise scaling and extrapolation, the two key components in the technique. We introduce unitary folding and parameterized noise scaling. These are digital noise scaling frameworks, i.e. one can apply them using only gate-level access common to most quantum instruction sets. We also study different extrapolation methods, including a new adaptive protocol that uses a statistical inference framework. Benchmarks of our techniques show error reductions of 18X to 24X over non-mitigated circuits and demonstrate ZNE's effectiveness at larger qubit numbers than have been tested previously. In addition to presenting new results, this work is a self-contained introduction to the practical use of ZNE by quantum programmers.
Near term quantum processors operate in a noise dominated regime, motivating error mitigation techniques that recover accurate expectation values without full fault tolerance. Zero Noise Extrapolation (ZNE) is a widely used but biased error mitigation method that lacks rigorous error bounds. Its effective application requires nontrivial technical choices, most notably the selection of noise scaling factors and extrapolation models, making ZNE sensitive to user expertise and often necessitating costly trial and error procedures. Here, we introduce Folding Free Zero Noise Extrapolation (FF-ZNE), a method that removes the need for noise factor selection by achieving effective noise amplification without circuit folding. FF-ZNE exploits isomorphic hardware layouts with distinct native noise profiles, such that executing a fixed circuit across these layouts induces controllable variations in the effective noise strength. Under a depolarizing noise model, we analytically show that the resulting extrapolation admits a fixed linear form, eliminating extrapolator choice and enabling a seamless, user independent mitigation procedure. We further propose two algorithms that identify sets of isomorphic hardware layouts on which a given circuit yields sufficiently distinct expectation values to enable reliable zero noise extrapolation. Experiments on a 133 qubit IBM Quantum device demonstrate that FF-ZNE yields mitigated expectation values with average deviations of ~6% and 4.5% for up to 50 qubit EfficientSU2 (sparse) and Hamiltonian simulation (dense) circuits, respectively. The method is thus scalable and applicable to a broad range of circuits. By eliminating noise factor and extrapolator selection, FF-ZNE transforms zero noise extrapolation from a technique requiring expert tuning into a practical, scalable, and broadly accessible error mitigation method for current quantum hardware.
We propose a quantum error mitigation strategy for the variational quantum eigensolver (VQE) algorithm. We find, via numerical simulation, that very small amounts of coherent noise in VQE can cause substantially large errors that are difficult to suppress by conventional mitigation methods, and yet our proposed mitigation strategy is able to significantly reduce these errors. The proposed strategy is a combination of previously reported techniques, namely randomized compiling (RC) and zero-noise extrapolation (ZNE). Intuitively, randomized compiling turns coherent errors in the circuit into stochastic Pauli errors, which facilitates extrapolation to the zero-noise limit when evaluating the cost function. Our numerical simulation of VQE for small molecules shows that the proposed strategy can mitigate energy errors induced by various types of coherent noise by up to two orders of magnitude.
Quantum computers in the NISQ era are prone to noise. A range of quantum error mitigation techniques has been proposed to address this issue. Zero-noise extrapolation (ZNE) stands out as a promising one. ZNE involves increasing the noise levels in a circuit and then using extrapolation to infer the zero noise case from the noisy results obtained. This paper presents a novel ZNE approach that does not require circuit folding or noise scaling to mitigate depolarizing and/or decoherence noise. To mitigate depolarizing noise, we propose leveraging the extreme/infinite noisy case, which allows us to avoid circuit folding. Specifically, the circuit output with extreme noise becomes the maximally mixed state. We show that using circuit-reliability metrics, simple linear extrapolation can effectively mitigate depolarizing noise. With decoherence noise, different states decay into the all-zero state at a rate that depends on the number of excited states and time. Therefore, we propose a state- and latency-aware exponential extrapolation that does not involve folding or scaling. When dealing with a quantum system affected by both decoherence and depolarizing noise, we propose to use our two mitigation techniques in sequence: first applying decoherence error mitigation, followed by depolarizing error mitigation. A common limitation of ZNE schemes is that if the circuit of interest suffers from high noise, scaling-up noise levels could not provide useful data for extrapolation. We propose using circuit-cut techniques to break a large quantum circuit into smaller sub-circuits to overcome this limitation. This way, the noise levels of the sub-circuits are lower than the original circuit, and ZNE can become more effective in mitigating their noises.
Reliable benchmarking of Quantum Error Mitigation (QEM) requires distinguishing genuine improvements from artefacts of the post-processing arithmetic. In this paper, we expose a failure mode in Richardson Zero-Noise Extrapolation (ZNE), a widely used technique routinely (and often implicitly) relied upon in benchmarks and experiments. When noise amplification operates beyond usable signals - a regime that is quickly reached on current hardware for non-trivial circuits - we show that the extrapolation no longer reflects the underlying physics, but collapses into a fixed rescaling of a single noisy measurement, producing a bogus apparent improvement that is independent of noise amplification. This poses a rarely considered threat to the validity of many empirical evaluations in quantum computing. Measurements on real hardware (IQM Euro-Q-Exa) confirm this collapse with ordinary folding alone: as circuit depth erodes the signal, the reported estimate decouples from the truth and overshoots the ideal by up to 21%. We further introduce a matched-cost "garbage-folding" negative control that carries no usable signal yet reports a larger apparent improvement than genuine folding - showing that the magnitude of an improvement is not evidence of its correctness - alongside a zero-cost check flagging the artefact from data a benchmark already holds. We distil both into a short reporting checklist for ZNE benchmarks.
Current noisy intermediate-scale quantum (NISQ) trapped-ion devices are subject to errors which can significantly impact the accuracy of calculations if left unchecked. A form of error mitigation called zero noise extrapolation (ZNE) can decrease an algorithm's sensitivity to these errors without increasing the number of required qubits. Here we explore different methods for integrating this error mitigation technique into the Variational Quantum Eigensolver (VQE) algorithm for calculating the ground state of the HeH+{\text{HeH}}^{+}HeH+ molecule at 0.8A˚0.8\phantom{\rule{3.33333pt}{0ex}}\text{\AA{}}0.8A˚ in the presence of experimental noise. Using the Quantum Scientific Computing Open User Testbed (QSCOUT) trapped-ion device, we test three methods of scaling noise for extrapolation: time stretching the two-qubit gates, scaling the sideband detuning parameter, and inserting two-qubit gate identity operations into the ansatz circuit. We find that time stretching and sideband detuning scaling fail to scale the noise on our particular hardware in a way that can be extrapolated to zero noise. Scaling our noise with global gate identity insertions and extrapolating after variational optimization, we achieve error suppression of 96.896.8%96.8, resulting in an energy estimate within $\ensuremath{-}0.004\ifmmode\pm\else\textpm\fi{}0.04$ hartree of the ground state energy. This is an improvement, but still outside the chemical accuracy threshold of 0.0016 hartree. Our results show that the efficacy of this error mitigation technique depends on choosing the correct implementation for a given device architecture.