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arXiv:2605.02066 · Physical Review Research

Accelerating Noisy Variational Quantum Algorithms with Physics-Informed Denoising Networks

Jie Liu, Xin Wang

quant-phcond-mat.dis-nnphysics.comp-phSubmitted May 3, 2026• Announced May 5, 2026• 0 citations
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Abstract

Variational quantum algorithms are promising for near-term quantum computing, but are severely limited by hardware noise and the substantial circuit overhead required for error mitigation methods such as Zero-Noise Extrapolation (ZNE). We propose a Physics-Informed Denoising Network (PIDN) that reduces the cost of ZNE by learning a surrogate model of its optimization dynamics. By viewing the variational update as a trajectory in the parameter space, PIDN is trained to reproduce ZNE-mitigated expectation values and gradient directions while incorporating a physics-informed loss that preserves the gradient descent dynamics. Once trained, PIDN replaces repeated multi-noise evaluations with denoised expectation and gradient estimation directly from the current noisy observation and the historical trajectory, significantly reducing circuit executions. We benchmark the approach on the quantum approximate optimization algorithm for 3-regular graphs, Sherrington-Kirkpatrick, and transverse-field Ising models, as well as the variational quantum eigensolver for LiH, BeH$_2$ and H$_2$O. Across all tasks, PIDN attains performance comparable to ZNE, while reducing the number of circuit executions by a factor of approximately 4 to 6. Gradient cosine similarity with ZNE remains above 0.95 throughout training. Robustness analysis shows that PIDN fails only when ZNE itself becomes unreliable, and ablation studies confirm the necessity of the physics-informed loss for maintaining directional consistency. We further find that PIDN tracks optimization dynamics most accurately when the effective loss landscape retains strong low-frequency structure. These results establish PIDN as a scalable, resource-efficient strategy for noise-resilient variational optimization in the noisy intermediate-scale quantum regime.

Comments
19 pages, 9 figs

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Variational quantum algorithms are promising for near-term quantum computing, but are severely limited by hardware noise and the substantial circuit overhead required for error mitigation methods such as Zero-Noise Extrapolation (ZNE). We propose a Physics-Informed Denoising Network (PIDN) that reduces the cost of ZNE by learning a surrogate model of its optimization dynamics. By viewing the variational update as a trajectory in the parameter space, PIDN is trained to reproduce ZNE-mitigated expectation values and gradient directions while incorporating a physics-informed loss that preserves the gradient descent dynamics. Once trained, PIDN replaces repeated multi-noise evaluations with denoised expectation and gradient estimation directly from the current noisy observation and the historical trajectory, significantly reducing circuit executions. We benchmark the approach on the quantum approximate optimization algorithm for 3-regular graphs, Sherrington-Kirkpatrick, and transverse-field Ising models, as well as the variational quantum eigensolver for LiH, BeH2_22​ and H2_22​O. Across all tasks, PIDN attains performance comparable to ZNE, while reducing the number of circuit executions by a factor of approximately 4 to 6. Gradient cosine similarity with ZNE remains above 0.95 throughout training. Robustness analysis shows that PIDN fails only when ZNE itself becomes unreliable, and ablation studies confirm the necessity of the physics-informed loss for maintaining directional consistency. We further find that PIDN tracks optimization dynamics most accurately when the effective loss landscape retains strong low-frequency structure. These results establish PIDN as a scalable, resource-efficient strategy for noise-resilient variational optimization in the noisy intermediate-scale quantum regime.
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Variational quantum circuits (VQCs) solving partial differential equations (PDEs) on near-term quantum hardware face a critical challenge: hardware noise degrades solution fidelity and disrupts convergence. We present a systematic study of three noise channels; depolarizing, amplitude damping, and bit-flip on VQCs constrained by PDE residual loss functions for the heat equation, Burgers' equation, and the Saint-Venant shallow water equations. We benchmark three error mitigation strategies: zero-noise extrapolation (ZNE) via Richardson polynomial fitting, probabilistic error cancellation (PEC), and measurement error mitigation through inverse confusion matrices. Our numerical experiments on 6-qubit, 4-layer circuits demonstrate that ZNE reduces absolute error by 82-96% at low noise (p = 0.001), with effectiveness degrading gracefully at higher noise strengths. We prove analytically and confirm numerically that physics-constrained circuits exhibit inherent noise resilience: at p = 0.01, constrained circuits maintain 25-47% higher fidelity than unconstrained counterparts, with the advantage scaling with PDE complexity. PEC provides near-exact correction at low gate counts but incurs exponential sampling overhead, rendering it impractical beyond ~60 gates at p >= 0.02. Error budget decomposition reveals that systematic errors dominate at all noise levels (43-58%), while the PDE residual component grows from ~10% to ~31% as noise increases, indicating that physics constraints absorb noise through structured gradient information. These results establish practical guidelines for deploying variational PDE solvers on NISQ hardware.
Noisy Intermediate-Scale Quantum (NISQ) devices show great promise for quantum advantage via Parametrized Quantum Circuits (PQCs) and Variational Quantum Algorithms (VQAs). Due to hardware imperfections, however, especially barren plateaus and environmental Pauli noise, the cost landscape is highly distorted, resulting in inaccurate classical optimization during training. To overcome these challenges, a robust quantum gradient descent framework is presented with the integration of error mitigation directly within the optimization loop. A noise-resilient parameter-shift rule is defined and modeled analytically, as is a variant of stochastic gradient descent with real-time Pauli noise mitigation. The framework is based on a 6-qubit system, which is tested on the Max-Cut problem in the presence of different amounts of depolarizing noise. It is shown experimentally that the proposed algorithm is able to achieve the final cost error of 0.045 under significant noise, whereas the standard quantum gradient descent fails to achieve better than 0.320 under this noise. Moreover, the methodology is consistent, converging without a noise-induced flat landscape and without local minima. The method offers a scalable route towards future applications of quantum machine learning on non-fault-tolerant hardware that does not suffer from the large sampling overhead often associated with conventional error mitigation techniques.
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