Quantum computing is entering a period in which progress will be shaped as much by advances in computer science as by improvements in hardware. The central thesis of this report is that early fault-tolerant quantum computing shifts many of the primary bottlenecks from device physics alone to computer-science-driven system design, integration, and evaluation. While large-scale, fully fault-tolerant quantum computers remain a long-term objective, near- and medium-term systems will support early fault-tolerant computation with small numbers of logical qubits and tight constraints on error rates, connectivity, latency, and classical control. How effectively such systems can be used will depend on advances across algorithms, error correction, software, and architecture. This report identifies key research challenges for computer scientists and organizes them around these four areas, each centered on a fundamental question.
Quantum computing is entering a period in which progress will be shaped as much by advances in computer science as by improvements in hardware. The central thesis of this report is that early fault-tolerant quantum computing shifts many of the primary bottlenecks from device physics alone to computer-science-driven system design, integration, and evaluation. While large-scale, fully fault-tolerant quantum computers remain a long-term objective, near- and medium-term systems will support early fault-tolerant computation with small numbers of logical qubits and tight constraints on error rates, connectivity, latency, and classical control. How effectively such systems can be used will depend on advances across algorithms, error correction, software, and architecture. This report identifies key research challenges for computer scientists and organizes them around these four areas, each centered on a fundamental question.
Quantum computing is an emerging computational paradigm that uses the principles of quantum mechanics, including superposition, entanglement, and quantum interference, to process information in fundamentally different ways from classical computers. During the last decade, quantum computing has progressed from theoretical research toward experimental and cloud-accessible systems. Recent developments have focused on increasing the number and quality of qubits, reducing gate errors, developing quantum error correction, improving quantum software, and integrating quantum processors with classical high-performance computing systems. Despite significant progress, practical large-scale quantum computing remains challenging because quantum states are extremely sensitive to environmental disturbances, resulting in decoherence and computational errors. Other challenges include limited qubit coherence time, gate fidelity, scalability, cryogenic requirements, quantum error correction overhead, hardware connectivity, programming complexity, and the difficulty of demonstrating useful quantum advantage for real-world applications. Recent developments from major research organizations indicate a shift from simply increasing physical qubit counts toward building reliable logical qubits and fault-tolerant quantum systems. Google has reported progress toward error-corrected logical qubits, while IBM\\\'s roadmap focuses on increasingly complex processors, modular architectures, quantum-classical integration, and fault-tolerant systems. Microsoft is pursuing a topological-qubit approach aimed at scalable quantum computing. This paper reviews the current state of quantum computing, examines major technological and scientific challenges, analyzes current research directions, and identifies future opportunities in drug discovery, materials science, optimization, cryptography, artificial intelligence, finance, and scientific simulation. The study concludes that the most realistic future is likely to involve quantum-centric computing, in which quantum processors work together with classical CPUs, GPUs, high-performance computing systems, and quantum networks rather than completely replacing classical computers.
Quantum computing is a paradigm shift in computational science, where computational tasks that cannot be computationally tackled with binary computing systems can be tackled using quantum mechanics principles, including superposition, entanglement, and quantum interference. The present paper gives a comprehensive summary of the present condition of quantum computing, including the most advanced hardware systems, such as topological qubits, photonics processors, trapped-ion systems and superconducting qubits, and their corresponding advantages and technical challenges. Also, quantum algorithms, including the Quantum Approximate Optimization Algorithm (QAOA) and the variational quantum eigen solvers (VQE), include a summary of the first algorithm, Shor's factorization method, and the second algorithm, Grover's search algorithm. Applications of such algorithms are evaluated in such areas as financial modeling, machine learning, material science, drug discovery, and cryptography. Taking into account the information provided by large research facilities and technology firms, the conditions under which quantum systems can outperform conventional technology, such a concept as quantum advantage is given specific focus in this review. Moreover, this paper pays particular attention to the key barriers to effective implementation, such as qubit decoherence, large error rates, scalability issues, and the lack of fault-tolerant quantum devices that can be sold commercially. Regarding the noisy intermediate-scale quantum (NISQ) devices that are expected to be available in the near future, we discuss novel approaches to quantum error correction, especially surface code and concatenated code. The quantum software industry, such as IBM Qiskit, Google Cirq, and Microsoft Q, and an evaluation of quantum workforce and research facility readiness across the globe is also discussed. In the end, this work highlights essential potential future paths, such as standards for post-quantum cryptography, hybrid quantum-classical computation, quantum networking and the quantum internet, and the long-term aims for universal fault- tolerant quantum computers. The review should provide researchers, graduate students, and practitioners with a systematic and up-to-date base to understand the fast-growing discipline of quantum computing and its extensive implications on science and business.
In recent years, research in quantum computing has largely focused on two approaches: near-term intermediate-scale quantum (NISQ) computing and future fault-tolerant quantum computing (FTQC). A growing body of research into early fault-tolerant quantum computing (EFTQC) is exploring how to utilize quantum computers during the transition between these two eras. However, without agreed-upon characterizations of this transition, it is unclear how best to utilize EFTQC architectures. We argue for the perspective that this transition period will be characterized by a law of diminishing returns in quantum error correction (QEC), where the ability of the architecture to maintain quality operations at scale determines the point of diminishing returns. Two challenges emerge from this picture: how to model this phenomenon of diminishing return of QEC as the performance of devices is continually improving and how to design algorithms to make the most use of these devices. To address these challenges, we present models for the performance of EFTQC architectures, capturing the diminishing returns of QEC. We then use these models to elucidate the regimes in which algorithms suited to such architectures are advantageous. As a concrete example, we show that for the canonical task of phase estimation, in a regime of moderate scalability and using just over one million physical qubits, the “reach” of the quantum computer can be extended (compared to the standard approach) from 90-qubit instances to over 130-qubit instances using a simple early fault-tolerant quantum algorithm, which reduces the number of operations per circuit by a factor of 100 and increases the number of circuit repetitions by a factor of 10 000. This clarifies the role that such algorithms might play in the era of limited-scalability quantum computing. Published by the American Physical Society 2024
Quantum computing represents a transformative paradigm that exploits the principles of quantum mechanics—superposition, entanglement, and quantum interference—to perform computations beyond the capabilities of classical computers. This review presents a comprehensive overview of the fundamental concepts underlying quantum computation, including qubits, quantum gates, quantum algorithms and measurement theory. It further examines major physical implementations of quantum computers, such as superconducting circuits, trapped ions, photonic systems, spin-based qubits, and topological approaches, highlighting their operational principles, advantages, and technological limitations. Key challenges hindering large-scale quantum computation—decoherence, error rates, qubit scalability, and fault tolerance—are critically discussed. Additionally, recent progress in quantum error correction, hybrid quantum–classical algorithms, and hardware optimization is summarized. The review concludes by outlining future research directions and potential applications of quantum computing in cryptography, materials science, optimization, and drug discovery. By integrating theoretical foundations with experimental advancements, this article aims to provide a clear and accessible reference for students, researchers, and scientists entering the rapidly evolving field of quantum computing.
The predictive simulation of molecules and materials has had a broad and significant impact. It nevertheless remains constrained by the cost of accurately treating electronic correlation, excited states, and complex energy landscapes. Quantum computing offers a fundamentally different computational paradigm in which quantum states are encoded and manipulated directly rather than approximated on classical hardware. Here we discuss where this approach may provide a genuine scientific advantage in chemistry, materials science, and biochemistry. Promising directions include the high-accuracy treatment of correlated active spaces, improved excited-state simulations, and accelerated exploration of combinatorial structure spaces. The central challenge is therefore not qubit scaling alone, but demonstrably chemically meaningful gains in predictive reliability. We argue that near-term value is most likely to come from disciplined workflow integration rather than wholesale replacement of classical methods. Noisy physical devices, error-mitigated utility experiments, early fault-tolerant devices, and fully fault-tolerant quantum computers offer different scientific prospects, and claims of usefulness must be tied to the specific regime being discussed. Quantum computing will become scientifically valuable when it demonstrably reduces uncertainty in computed energies, rates, spectra, or materials stability after the full costs of state preparation, measurement, error handling, and coupling to classical simulation are included.
Quantum computing is advancing rapidly, offering the potential to transform computational paradigms and tackle problems that are intractable for classical systems. Realizing practical quantum systems demands the development of an entirely new computing stack—from qubits and quantum processors to components, wiring and control electronics, transpilers, error handling, software, algorithms, and the compute architecture to integrate quantum and classical resources at scale. This plenary will provide an overview of the current state of quantum computing and outline the milestones on the path toward building a large-scale, fault-tolerant quantum computer by 2029. The significant improvements in hardware, software, and system integration, pushing the performance of quantum computing to reach quantum utility and advance toward quantum advantage, will be presented. Breakthroughs in error correction and a modular approach indicated in the IBM Quantum Roadmap outline a clear path to quantum systems using 200 logical qubits and 100 million quantum operations by 2029 and 2,000 logical qubits a few years later. Furthermore, advances in quantum algorithms, combined with the integration of quantum systems and high-performance computing (HPC), will unlock powerful synergies—accelerating the timeline for applications previously considered to be far in the future.