To address the growing needs for scalable High Performance Computing (HPC) and Quantum Computing (QC) integration, we present our HPC-QC full stack framework and its hybrid workload development capability with modular hardware/device-agnostic software integration approach. The latest development in extensible interfaces for quantum programming, dispatching, and compilation within existing mature HPC programming environment are demonstrated. Our HPC-QC full stack enables high-level, portable invocation of quantum kernels from commercial quantum SDKs within HPC meta-program in compiled languages (C/C++ and Fortran) as well as Python through a quantum programming interface library extension. An adaptive circuit knitting hypervisor is being developed to partition large quantum circuits into sub-circuits that fit on smaller noisy quantum devices and classical simulators. At the lower-level, we leverage Cray LLVM-based compilation framework to transform and consume LLVM IR and Quantum IR (QIR) from commercial quantum software frontends in a retargetable fashion to different hardware architectures. Several hybrid HPC-QC multi-node multi-CPU and GPU workloads (including solving linear system of equations, quantum optimization, and simulating quantum phase transitions) have been demonstrated on HPE EX supercomputers to illustrate functionality and execution viability for all three components developed so far. This work provides the framework for a unified quantum-classical programming environment built upon classical HPC software stack (compilers, libraries, parallel runtime and process scheduling).
To address the growing needs for scalable High Performance Computing (HPC) and Quantum Computing (QC) integration, we present our HPC-QC full stack framework and its hybrid workload development capability with modular hardware/device-agnostic software integration approach. The latest development in extensible interfaces for quantum programming, dispatching, and compilation within existing mature HPC programming environment are demonstrated. Our HPC-QC full stack enables high-level, portable invocation of quantum kernels from commercial quantum SDKs within HPC meta-program in compiled languages (C/C++ and Fortran) as well as Python through a quantum programming interface library extension. An adaptive circuit knitting hypervisor is being developed to partition large quantum circuits into sub-circuits that fit on smaller noisy quantum devices and classical simulators. At the lower-level, we leverage Cray LLVM-based compilation framework to transform and consume LLVM IR and Quantum IR (QIR) from commercial quantum software frontends in a retargetable fashion to different hardware architectures. Several hybrid HPC-QC multi-node multi-CPU and GPU workloads (including solving linear system of equations, quantum optimization, and simulating quantum phase transitions) have been demonstrated on HPE EX supercomputers to illustrate functionality and execution viability for all three components developed so far. This work provides the framework for a unified quantum-classical programming environment built upon classical HPC software stack (compilers, libraries, parallel runtime and process scheduling).
To harness the power of quantum computing (QC) in the near future, tight and efficient integration of QC with high performance computing (HPC) infrastructure (both on the software (SW) and the hardware (HW) level) is crucial. This paper addresses the development of a unified quantum platform (UQP) and how it is being integrated into the HPC ecosystem. It builds on the concepts of hybrid high performance computing - quantum computing (HPCQC) workflows and a unified HPCQC toolchain, introduced in our previous work and makes the next needed step: it unifies the low-level interface between the existing classical HPC systems and the emerging quantum hardware technologies, including but not limited to machines based on superconducting qubits, neutral atoms or trapped ions. The UQP consists of three core components: a runtime library, an instruction set architecture (ISA) and a quantum control processor (QCP) micro-architecture. In particular, this work contributes a unified HPCQC runtime library that bridges the gap between programming systems built on quantum intermediate representation (QIR) standard with a novel, unified hybrid ISA. It then introduces the initial extension of an ISA and QCP micro-architecture to be platform and technology agnostic and enables it as an efficient execution platform. The UQP has been verified to ensure correctness. Further, our performance analysis shows that the execution time and memory requirements of the runtime library scale super-linearly with number of qubits, which is critical to support scalability efforts in OC hardware.
High-performance computing (HPC) has evolved over decades through multiple architectural transitions, from vector supercomputers to massively parallel CPU clusters and GPU-accelerated systems, continuously expanding the frontier of scientific discovery. With the emergence of quantum processing units (QPUs) as practical computational accelerators, a new opportunity arises to further extend this trajectory by integrating quantum and classical computing paradigms. Building on the emerging vision of Quantum Integrated High-Performance Computing (QHPC), this paper contributes a full-stack layered architecture that integrates QPUs as first-class accelerators within, not merely alongside, the classical HPC software and hardware stack, with tight, on-premise quantum-classical coupling as its defining characteristic. The architecture comprises of unified resource management, quantum-aware scheduling, hybrid workflow orchestration, middleware and programming abstraction, interconnect technologies, and a tiered execution model enabling seamless workload partitioning across classical and quantum backends. A central aspect of this architecture is a strong user requests abstraction layer that exposes heterogeneous resources through a unified job submission interface, similar in spirit to existing schedulers such as Slurm, allowing users to describe workloads in a consistent template independent of underlying compute type or location. Drawing insights from prior accelerator integration eras, we outline how QHPC can support emerging workloads in quantum chemistry, materials discovery, combinatorial optimization, and climate modeling. We conclude by highlighting open challenges in building scalable, reliable, and programmable quantum-classical infrastructures that seamlessly connect global users to heterogeneous compute resources for future quantum-classical HPC ecosystems.
High-performance computing (HPC) has evolved over decades through multiple architectural transitions, from vector supercomputers to massively parallel CPU clusters and GPU-accelerated systems, continuously expanding the frontier of scientific discovery. With the emergence of quantum processing units (QPUs) as practical computational accelerators, a new opportunity arises to further extend this trajectory by integrating quantum and classical computing paradigms. Building on the emerging vision of Quantum Integrated High-Performance Computing (QHPC), this paper contributes a full-stack layered architecture that integrates QPUs as first-class accelerators within, not merely alongside, the classical HPC software and hardware stack, with tight, on-premise quantum–classical coupling as its defining characteristic. The architecture comprises of unified resource management, quantum-aware scheduling, hybrid workflow orchestration, middleware and programming abstraction, interconnect technologies, and a tiered execution model enabling seamless workload partitioning across classical and quantum backends. A central aspect of this architecture is a strong user requests abstraction layer that exposes heterogeneous resources through a unified job submission interface, similar in spirit to existing schedulers such as Slurm, allowing users to describe workloads in a consistent template independent of underlying compute type or location. Drawing insights from prior accelerator integration eras, we outline how QHPC can support emerging workloads in quantum chemistry, materials discovery, combinatorial optimization, and climate modeling. We conclude by highlighting open challenges in building scalable, reliable, and programmable quantum–classical infrastructures that seamlessly connect global users to heterogeneous compute resources for future quantum–classical HPC ecosystems.
To address the urgent need in the NISQ era for high-performance, scalable quantum compilers and to advance the integration of classical and quantum computing, we present QLLVM, an advanced Quantum-Classical co-compilation framework built on LLVM. To our knowledge, QLLVM delivers an end-to-end, LLVM-based compilation workflow that unifies the build of classical high-performance programs, including CUDA, MPI, and C++, together with quantum programs into a single executable. For quantum program compilation, QLLVM adopts a three-stage design: high-level optimizations are implemented in the MLIR Quantum dialect and then lowered to QIR, an LLVM IR-based representation, for low-level optimization and hardware mapping. Its extensible architecture and seamless interoperability with classical high-performance computing provide an efficient, flexible, industrial-grade compilation infrastructure for future quantum software development. Experimental results show that, on the MQTBench benchmark suite, QLLVM reduces circuit depth and gate counts compared with state-of-the-art compilers and demonstrates clear advantages in compiling hybrid classical-quantum programs.
In this work, we demonstrate hybrid High Performance Computing-Quantum Computing (HPCQC) workflows on a production petascale system. The demonstration combines three components: the SuperMUC-NG supercomputer at the Leibniz Supercomputing Centre (LRZ), a 20-qubit superconducting quantum processor provided by IQM Quantum Computers (IQM), and Munich Quantum Valley (MQV)'s Munich Quantum Software Stack (MQSS).
Integrating quantum processors into High Performance Computing (HPC) systems requires a heterogeneous software stack capable of orchestrating classical and quantum resources within established supercomputing workflows. MQSS treats Quantum Processing Units (QPUs) as scheduler-managed accelerators and it performs resource coordination following a two-level scheduling scheme. Slurm performs system-level allocation by exposing QPUs as Generic RESources (GRES), while the MQSS Quantum Resource Manager & Compiler Infrastructure (QRM&CI) performs just-in-time compilation and subsequent dispatch of quantum circuits.
To integrate with existing HPC operations without modifying the scheduler core, MQSS introduces an open-source SLURM Plugin Suite based on Prolog/Epilog scripts and SPANK modules. Experimental results show that hybrid HPCQC workflows can be executed without significant latency overhead compared to conventional workloads.
The presented architecture provides a portable integration model for quantum accelerators on large-scale HPC systems and is directly applicable to next-generation Hewlett Packard Enterprise (HPE) Cray platforms, including LRZ's upcoming 'Blue Lion' supercomputer.
The connection and eventual integration of High-Performance Computing (HPC) with Quantum Computing (QC) represents a transformative advancement in computational technology, promising significant enhancements in solving complex, previously intractable problems. This manuscript provides a comprehensive overview of the current state of HPC-QC interfacing, detailing architectural methodologies, software stack developments, middleware functionalities, and hardware integration strategies. It critically assesses existing hardware-level integration models, ranging from standalone and loosely-coupled architectures to tightly-integrated and on-node systems. The software ecosystem is analyzed, highlighting prominent frameworks such as Qiskit, PennyLane, CUDA-Q, and middleware solutions like Pilot-Quantum, essential for seamless hybrid computing environments. Furthermore, the manuscript discusses practical applications in optimization, machine learning, and many-body dynamics, where hybrid HPC-QC systems can offer substantial advantages. It also describes existing challenges, including hardware limitations (coherence, scalability, connectivity), software maturity, communication overhead, resource management complexities, and cost factors. Finally, future directions towards tighter hardware and software integration are discussed, emphasizing ongoing research developments and emerging trends that promise to expand the capabilities and accessibility of hybrid HPC-QC systems.