Challenges
Datasets
Workspaces
Papers
Discussions
Leaderboard
Log inSign up
Challenges
Datasets
Workspaces
Papers
Discussions
Leaderboard
Blog
Job Board
Q3AS

© 2026 Aqora Quantum S.A.S.

TermsPrivacyLegal Notice

arXiv:2407.18527 · IEEE International Conference on Quantum Computing and Engineering (QCE)

Integration of Quantum Accelerators into HPC: Toward a Unified Quantum Platform

Amr Elsharkawy, Xiaorang Guo, Martin Schulz

Published Sep 15, 2024• 18 citations
arXivHTMLPDF

Abstract

To harness the power of quantum computing (QC) in the near future, tight and efficient integration of QC with high performance computing (HPC) infrastructure (both on the software (SW) and the hardware (HW) level) is crucial. This paper addresses the development of a unified quantum platform (UQP) and how it is being integrated into the HPC ecosystem. It builds on the concepts of hybrid high performance computing - quantum computing (HPCQC) workflows and a unified HPCQC toolchain, introduced in our previous work and makes the next needed step: it unifies the low-level interface between the existing classical HPC systems and the emerging quantum hardware technologies, including but not limited to machines based on superconducting qubits, neutral atoms or trapped ions. The UQP consists of three core components: a runtime library, an instruction set architecture (ISA) and a quantum control processor (QCP) micro-architecture. In particular, this work contributes a unified HPCQC runtime library that bridges the gap between programming systems built on quantum intermediate representation (QIR) standard with a novel, unified hybrid ISA. It then introduces the initial extension of an ISA and QCP micro-architecture to be platform and technology agnostic and enables it as an efficient execution platform. The UQP has been verified to ensure correctness. Further, our performance analysis shows that the execution time and memory requirements of the runtime library scale super-linearly with number of qubits, which is critical to support scalability efforts in OC hardware.

DOI
10.1109/qce60285.2024.00097

Related papers

Toward a Unified Hybrid HPCQC Toolchain

Philipp Seitz, Amr Elsharkawy, Xiao-Ting Michelle To +1 more

In the expanding field of quantum computing (QC), efficient and seamless integration of QC and high performance computing (HPC) elements (e.g., quantum hardware, classical hardware, and software infrastructure on both sides) plays a crucial role. This paper addresses the development of a unified toolchain designed for hybrid quantum-classical systems. Our work proposes a design for a unified hybrid high performance computing - quantum computing (HPCQC) toolchain that tackles pressing issues such as scalability, cross-technology execution, and ahead-of-time (AOT) optimization.

arXiv:2309.01661•IEEE International Conference on Quantum Computing and Engineering (QCE)•Sep 17, 2023•9 citations

Integration of Quantum Accelerators with High Performance Computing—A Review of Quantum Programming Tools

Amr Elsharkawy, Xiao-Ting Michelle To, Philipp Seitz +9 more

Quantum computing (QC) introduces a novel mode of computation with the possibility of greater computational power that remains to be exploitedpresenting exciting opportunities for high-performance computing (HPC) applications. However, recent advancements in the field have made clear that QC does not supplant conventional HPC, but can rather be incorporated into current heterogeneous HPC infrastructures as an additional accelerator, thereby enabling the optimal utilization of both paradigms. The desire for such integration significantly affects the development of software for quantum computers, which in turn influences the necessary software infrastructure. To date, previous review articles have investigated various quantum programming tools (QPTs) (such as languages, libraries, frameworks) in their ability to program, compile, and execute quantum circuits. However, the integration effort with classical HPC frameworks or systems has not been addressed. This study aims to characterize existing QPTs from an HPC perspective, investigating if existing QPTs have the potential to be efficiently integrated with classical computing models and determining where work is still required. This work structures a set of criteria into an analysis blueprint that enables HPC scientists to assess whether a QPT is suitable for a high-performance computing quantum computing (HPCQC) environment.

arXiv:2309.06167•ACM Transactions on Quantum Computing•Jun 10, 2025•25 citations

Quantum Integrated High-Performance Computing: Envisioning a Layered Architecture for Next-Generation Hybrid Computing Infrastructure

Suman Raj, Siva Sai, Yogesh Simmhan +2 more

High-performance computing (HPC) has evolved over decades through multiple architectural transitions, from vector supercomputers to massively parallel CPU clusters and GPU-accelerated systems, continuously expanding the frontier of scientific discovery. With the emergence of quantum processing units (QPUs) as practical computational accelerators, a new opportunity arises to further extend this trajectory by integrating quantum and classical computing paradigms. Building on the emerging vision of Quantum Integrated High-Performance Computing (QHPC), this paper contributes a full-stack layered architecture that integrates QPUs as first-class accelerators within, not merely alongside, the classical HPC software and hardware stack, with tight, on-premise quantum-classical coupling as its defining characteristic. The architecture comprises of unified resource management, quantum-aware scheduling, hybrid workflow orchestration, middleware and programming abstraction, interconnect technologies, and a tiered execution model enabling seamless workload partitioning across classical and quantum backends. A central aspect of this architecture is a strong user requests abstraction layer that exposes heterogeneous resources through a unified job submission interface, similar in spirit to existing schedulers such as Slurm, allowing users to describe workloads in a consistent template independent of underlying compute type or location. Drawing insights from prior accelerator integration eras, we outline how QHPC can support emerging workloads in quantum chemistry, materials discovery, combinatorial optimization, and climate modeling. We conclude by highlighting open challenges in building scalable, reliable, and programmable quantum-classical infrastructures that seamlessly connect global users to heterogeneous compute resources for future quantum-classical HPC ecosystems.

quant-pharXiv:2604.19814•Apr 20, 2026•0 citations

A Full Stack Framework for High Performance Quantum-Classical Computing

Xin Zhan, Katherine Grace Johnson, Aniello Esposito +5 more

To address the growing needs for scalable High Performance Computing (HPC) and Quantum Computing (QC) integration, we present our HPC-QC full stack framework and its hybrid workload development capability with modular hardware/device-agnostic software integration approach. The latest development in extensible interfaces for quantum programming, dispatching, and compilation within existing mature HPC programming environment are demonstrated. Our HPC-QC full stack enables high-level, portable invocation of quantum kernels from commercial quantum SDKs within HPC meta-program in compiled languages (C/C++ and Fortran) as well as Python through a quantum programming interface library extension. An adaptive circuit knitting hypervisor is being developed to partition large quantum circuits into sub-circuits that fit on smaller noisy quantum devices and classical simulators. At the lower-level, we leverage Cray LLVM-based compilation framework to transform and consume LLVM IR and Quantum IR (QIR) from commercial quantum software frontends in a retargetable fashion to different hardware architectures. Several hybrid HPC-QC multi-node multi-CPU and GPU workloads (including solving linear system of equations, quantum optimization, and simulating quantum phase transitions) have been demonstrated on HPE EX supercomputers to illustrate functionality and execution viability for all three components developed so far. This work provides the framework for a unified quantum-classical programming environment built upon classical HPC software stack (compilers, libraries, parallel runtime and process scheduling).

arXiv:2510.20128•Oct 23, 2025•0 citations

Quantum Integrated High-Performance Computing: Envisioning a layered architecture for next-generation hybrid computing infrastructure

Suman Raj, Siva Sai, Yogesh L. Simmhan +2 more

High-performance computing (HPC) has evolved over decades through multiple architectural transitions, from vector supercomputers to massively parallel CPU clusters and GPU-accelerated systems, continuously expanding the frontier of scientific discovery. With the emergence of quantum processing units (QPUs) as practical computational accelerators, a new opportunity arises to further extend this trajectory by integrating quantum and classical computing paradigms. Building on the emerging vision of Quantum Integrated High-Performance Computing (QHPC), this paper contributes a full-stack layered architecture that integrates QPUs as first-class accelerators within, not merely alongside, the classical HPC software and hardware stack, with tight, on-premise quantum–classical coupling as its defining characteristic. The architecture comprises of unified resource management, quantum-aware scheduling, hybrid workflow orchestration, middleware and programming abstraction, interconnect technologies, and a tiered execution model enabling seamless workload partitioning across classical and quantum backends. A central aspect of this architecture is a strong user requests abstraction layer that exposes heterogeneous resources through a unified job submission interface, similar in spirit to existing schedulers such as Slurm, allowing users to describe workloads in a consistent template independent of underlying compute type or location. Drawing insights from prior accelerator integration eras, we outline how QHPC can support emerging workloads in quantum chemistry, materials discovery, combinatorial optimization, and climate modeling. We conclude by highlighting open challenges in building scalable, reliable, and programmable quantum–classical infrastructures that seamlessly connect global users to heterogeneous compute resources for future quantum–classical HPC ecosystems.

Future Generation Computer Systems•Oct 17, 2026•0 citations

Interfacing Quantum Computing Systems with High-Performance Computing Systems: An Overview

Konstantinos Rallis, Ioannis Liliopoulos, Georgios D. Varsamis +4 more

The connection and eventual integration of High-Performance Computing (HPC) with Quantum Computing (QC) represents a transformative advancement in computational technology, promising significant enhancements in solving complex, previously intractable problems. This manuscript provides a comprehensive overview of the current state of HPC-QC interfacing, detailing architectural methodologies, software stack developments, middleware functionalities, and hardware integration strategies. It critically assesses existing hardware-level integration models, ranging from standalone and loosely-coupled architectures to tightly-integrated and on-node systems. The software ecosystem is analyzed, highlighting prominent frameworks such as Qiskit, PennyLane, CUDA-Q, and middleware solutions like Pilot-Quantum, essential for seamless hybrid computing environments. Furthermore, the manuscript discusses practical applications in optimization, machine learning, and many-body dynamics, where hybrid HPC-QC systems can offer substantial advantages. It also describes existing challenges, including hardware limitations (coherence, scalability, connectivity), software maturity, communication overhead, resource management complexities, and cost factors. Finally, future directions towards tighter hardware and software integration are discussed, emphasizing ongoing research developments and emerging trends that promise to expand the capabilities and accessibility of hybrid HPC-QC systems.

arXiv:2509.06205•Sep 7, 2025•1 citation
To harness the power of quantum computing (QC) in the near future, tight and efficient integration of QC with high performance computing (HPC) infrastructure (both on the software (SW) and the hardware (HW) level) is crucial. This paper addresses the development of a unified quantum platform (UQP) and how it is being integrated into the HPC ecosystem. It builds on the concepts of hybrid high performance computing - quantum computing (HPCQC) workflows and a unified HPCQC toolchain, introduced in our previous work and makes the next needed step: it unifies the low-level interface between the existing classical HPC systems and the emerging quantum hardware technologies, including but not limited to machines based on superconducting qubits, neutral atoms or trapped ions. The UQP consists of three core components: a runtime library, an instruction set architecture (ISA) and a quantum control processor (QCP) micro-architecture. In particular, this work contributes a unified HPCQC runtime library that bridges the gap between programming systems built on quantum intermediate representation (QIR) standard with a novel, unified hybrid ISA. It then introduces the initial extension of an ISA and QCP micro-architecture to be platform and technology agnostic and enables it as an efficient execution platform. The UQP has been verified to ensure correctness. Further, our performance analysis shows that the execution time and memory requirements of the runtime library scale super-linearly with number of qubits, which is critical to support scalability efforts in OC hardware.
In the expanding field of quantum computing (QC), efficient and seamless integration of QC and high performance computing (HPC) elements (e.g., quantum hardware, classical hardware, and software infrastructure on both sides) plays a crucial role. This paper addresses the development of a unified toolchain designed for hybrid quantum-classical systems. Our work proposes a design for a unified hybrid high performance computing - quantum computing (HPCQC) toolchain that tackles pressing issues such as scalability, cross-technology execution, and ahead-of-time (AOT) optimization.
Quantum computing (QC) introduces a novel mode of computation with the possibility of greater computational power that remains to be exploitedpresenting exciting opportunities for high-performance computing (HPC) applications. However, recent advancements in the field have made clear that QC does not supplant conventional HPC, but can rather be incorporated into current heterogeneous HPC infrastructures as an additional accelerator, thereby enabling the optimal utilization of both paradigms. The desire for such integration significantly affects the development of software for quantum computers, which in turn influences the necessary software infrastructure. To date, previous review articles have investigated various quantum programming tools (QPTs) (such as languages, libraries, frameworks) in their ability to program, compile, and execute quantum circuits. However, the integration effort with classical HPC frameworks or systems has not been addressed. This study aims to characterize existing QPTs from an HPC perspective, investigating if existing QPTs have the potential to be efficiently integrated with classical computing models and determining where work is still required. This work structures a set of criteria into an analysis blueprint that enables HPC scientists to assess whether a QPT is suitable for a high-performance computing quantum computing (HPCQC) environment.
High-performance computing (HPC) has evolved over decades through multiple architectural transitions, from vector supercomputers to massively parallel CPU clusters and GPU-accelerated systems, continuously expanding the frontier of scientific discovery. With the emergence of quantum processing units (QPUs) as practical computational accelerators, a new opportunity arises to further extend this trajectory by integrating quantum and classical computing paradigms. Building on the emerging vision of Quantum Integrated High-Performance Computing (QHPC), this paper contributes a full-stack layered architecture that integrates QPUs as first-class accelerators within, not merely alongside, the classical HPC software and hardware stack, with tight, on-premise quantum-classical coupling as its defining characteristic. The architecture comprises of unified resource management, quantum-aware scheduling, hybrid workflow orchestration, middleware and programming abstraction, interconnect technologies, and a tiered execution model enabling seamless workload partitioning across classical and quantum backends. A central aspect of this architecture is a strong user requests abstraction layer that exposes heterogeneous resources through a unified job submission interface, similar in spirit to existing schedulers such as Slurm, allowing users to describe workloads in a consistent template independent of underlying compute type or location. Drawing insights from prior accelerator integration eras, we outline how QHPC can support emerging workloads in quantum chemistry, materials discovery, combinatorial optimization, and climate modeling. We conclude by highlighting open challenges in building scalable, reliable, and programmable quantum-classical infrastructures that seamlessly connect global users to heterogeneous compute resources for future quantum-classical HPC ecosystems.
To address the growing needs for scalable High Performance Computing (HPC) and Quantum Computing (QC) integration, we present our HPC-QC full stack framework and its hybrid workload development capability with modular hardware/device-agnostic software integration approach. The latest development in extensible interfaces for quantum programming, dispatching, and compilation within existing mature HPC programming environment are demonstrated. Our HPC-QC full stack enables high-level, portable invocation of quantum kernels from commercial quantum SDKs within HPC meta-program in compiled languages (C/C++ and Fortran) as well as Python through a quantum programming interface library extension. An adaptive circuit knitting hypervisor is being developed to partition large quantum circuits into sub-circuits that fit on smaller noisy quantum devices and classical simulators. At the lower-level, we leverage Cray LLVM-based compilation framework to transform and consume LLVM IR and Quantum IR (QIR) from commercial quantum software frontends in a retargetable fashion to different hardware architectures. Several hybrid HPC-QC multi-node multi-CPU and GPU workloads (including solving linear system of equations, quantum optimization, and simulating quantum phase transitions) have been demonstrated on HPE EX supercomputers to illustrate functionality and execution viability for all three components developed so far. This work provides the framework for a unified quantum-classical programming environment built upon classical HPC software stack (compilers, libraries, parallel runtime and process scheduling).
High-performance computing (HPC) has evolved over decades through multiple architectural transitions, from vector supercomputers to massively parallel CPU clusters and GPU-accelerated systems, continuously expanding the frontier of scientific discovery. With the emergence of quantum processing units (QPUs) as practical computational accelerators, a new opportunity arises to further extend this trajectory by integrating quantum and classical computing paradigms. Building on the emerging vision of Quantum Integrated High-Performance Computing (QHPC), this paper contributes a full-stack layered architecture that integrates QPUs as first-class accelerators within, not merely alongside, the classical HPC software and hardware stack, with tight, on-premise quantum–classical coupling as its defining characteristic. The architecture comprises of unified resource management, quantum-aware scheduling, hybrid workflow orchestration, middleware and programming abstraction, interconnect technologies, and a tiered execution model enabling seamless workload partitioning across classical and quantum backends. A central aspect of this architecture is a strong user requests abstraction layer that exposes heterogeneous resources through a unified job submission interface, similar in spirit to existing schedulers such as Slurm, allowing users to describe workloads in a consistent template independent of underlying compute type or location. Drawing insights from prior accelerator integration eras, we outline how QHPC can support emerging workloads in quantum chemistry, materials discovery, combinatorial optimization, and climate modeling. We conclude by highlighting open challenges in building scalable, reliable, and programmable quantum–classical infrastructures that seamlessly connect global users to heterogeneous compute resources for future quantum–classical HPC ecosystems.
The connection and eventual integration of High-Performance Computing (HPC) with Quantum Computing (QC) represents a transformative advancement in computational technology, promising significant enhancements in solving complex, previously intractable problems. This manuscript provides a comprehensive overview of the current state of HPC-QC interfacing, detailing architectural methodologies, software stack developments, middleware functionalities, and hardware integration strategies. It critically assesses existing hardware-level integration models, ranging from standalone and loosely-coupled architectures to tightly-integrated and on-node systems. The software ecosystem is analyzed, highlighting prominent frameworks such as Qiskit, PennyLane, CUDA-Q, and middleware solutions like Pilot-Quantum, essential for seamless hybrid computing environments. Furthermore, the manuscript discusses practical applications in optimization, machine learning, and many-body dynamics, where hybrid HPC-QC systems can offer substantial advantages. It also describes existing challenges, including hardware limitations (coherence, scalability, connectivity), software maturity, communication overhead, resource management complexities, and cost factors. Finally, future directions towards tighter hardware and software integration are discussed, emphasizing ongoing research developments and emerging trends that promise to expand the capabilities and accessibility of hybrid HPC-QC systems.