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arXiv:2507.09243

Spin Squeezing in Electron Microscopy

Shiran Even-Haim, Ethan Nussinson, Roni Ben-Maimon, Alexey A. Gorlach, Ron Ruimy, Ephraim Shahmoon, Osip Schwartz, Ido E. Kaminer

Published Jul 12, 2025• 0 citations
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Abstract

Quantum metrology experiments in atomic physics and quantum optics have demonstrated measurement accuracy beyond the shot-noise limit via multi-particle entanglement. At the same time, electron microscopy, an essential tool for high-resolution imaging of biological systems, is severely constrained in its signal-to-noise ratio (SNR) by shot noise, due to the dose limit imposed by electron beam-induced damage. Here, we show theoretically that spin squeezing, a form of quantum metrology based on entanglement, is a natural fit for improving the SNR in electron microscopy. We investigate the generation of the necessary entangled states through electron-electron Coulomb interactions and quantum non-demolition measurements. Our results connect the fields of quantum metrology and electron interferometry, paving the way toward electron microscopy with SNR beyond the shot-noise limit.

DOI
10.48550/arxiv.2507.09243

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Quantum metrology experiments in atomic physics and quantum optics have demonstrated measurement accuracy beyond the shot-noise limit via multi-particle entanglement. At the same time, electron microscopy, an essential tool for high-resolution imaging of biological systems, is severely constrained in its signal-to-noise ratio (SNR) by shot noise, due to the dose limit imposed by electron beam-induced damage. Here, we show theoretically that spin squeezing, a form of quantum metrology based on entanglement, is a natural fit for improving the SNR in electron microscopy. We investigate the generation of the necessary entangled states through electron-electron Coulomb interactions and quantum non-demolition measurements. Our results connect the fields of quantum metrology and electron interferometry, paving the way toward electron microscopy with SNR beyond the shot-noise limit.
Quantum metrology enables us to estimate optical phase shifts beyond the shot noise limit. Applications include quantum-enhanced biological measurement [1], microscopy [2] and gravitational wave detection[3]. For two-mode N-photon system, the NOON state can achieve the highest possible phase sensitivity where multi-photon coherence between two states significantly contributes to improving the phase sensitivity. Another alternative approach to improve the phase sensitivity by use of squeezed states. Squeezing is usually characterized by reducing the quantum noise of desired observable at the expense of increasing the quantum noise for its non-commute partner. Because shot-noise limits the phase sensitivity of any classical states, the reduced quantum noise can be used for improving the phase sensitivity. Here we experimentally study the phase sensitivity of an optical spin-squeezed state by using linear optics. We generated the optical spin-squeezed state using one photon subtraction from a down converted photon source. To implement the sub-shot noise measurement, we used multiplexed photon number resolving detectors so that we can reconstruct the photon number statistics of the state. In the talk, we will analyse the generated state in terms of both squeezing and phase sensitivity by using Fisher information.
Quantum-enhanced metrology techniques offer ultra-precise timekeeping, allowing for breakthroughs in navigation systems, global positioning, medical and Biological imaging. Quantum metrology, a core application of quantum technologies, leverages non-classical states of light (such as entanglement and squeezing) to enhance measurement precision, sensitivity, and resolution beyond the classical limits, particularly the shot-noise limit. Its application to bio imaging and microscopy offers significant advantages for studying delicate biological specimens, which are often susceptible to damage from the intense light typically required by conventional high-resolution methods. The abstract highlights the potential of quantum properties of light to revolutionize bio imaging by providing a non-invasive, highly sensitive, and high-resolution platform for observing biological processes at fundamental scales.
The controlled generation of entanglement forms the basis for currently emerging ‘quantum technologies’, such as quantum simulation, computation, and metrology. In the field of quantum metrology, multi-particle entangled states, such as spin-squeezed states, are investigated as a means to improve measurement precision beyond the ‘standard quantum limit’. This limit arises from the quantum noise inherent in measurements on a finite number of uncorrelated particles and limits today’s best atomic clocks. Atom chips combine exquisite coherent control of ultracold atoms with a compact and robust setup, suggesting their use for quantum metrology with portable atomic clocks and interferometers. A severe limitation of atom chips, however, is that techniques to control atomic interactions and to generate entanglement have not been experimentally available so far. In this thesis, I present experiments where we generate for the first time multi-particle entanglement on an atom chip. We achieve this by controlling elastic collisional interactions with a state-dependent potential. We employ this novel technique to generate spin-squeezed states of a two-component Bose-Einstein condensate and show that they are a useful resource for quantum metrology, as they could be used to improve an interferometric measurement by 2.5 dB over the standard quantum limit. The state-dependent potential is created with the help of a coplanar microwave guide, which is integrated on our atom chip. In the vicinity of this waveguide a microwave nearfield is formed. When a Bose-Einstein condensate of 87Rb is brought into this near-field, the hyperfine energy levels of the atoms are shifted differentially due to the AC Zeeman effect. The strong gradients in the field can be used to state-selectively shift the minimum of a static magnetic atom trap and thus coherently split an ensemble of atoms which have been prepared in a superposition of two internal states. During this process, nonlinear atomic interactions lead to the formation of a spinsqueezed state. I tomographically analyze the produced state, reconstruct its Wigner function, and deduce that it is at least four-particle entangled. I compare our results with a dynamical multi-mode simulation which takes not only the atomic motion and internal state dynamics but also particle losses into account and find good agreement. Moreover, I use this comparison to identify technical noise sources in our experiment, which currently limit the achieved amount of squeezing, and make suggestions on how to eliminate them in future experiments. Our method can in principle create a very large amount of squeezing and entanglement and is applicable to a wide variety of atomic systems, in particular to those for which no convenient Feshbach resonance exists. We envisage the implementation of this technique in portable atomic clocks and interferometers operating beyond the standard quantum limit. Furthermore, it is a valuable tool for experiments on many-body quantum physics and could enable quantum information processing on atom chips.
Quantum metrology enables estimation of optical phase shifts with precision beyond the shot-noise limit. One way to exceed this limit is to use squeezed states, where the quantum noise of one observable is reduced at the expense of increased quantum noise for its complementary partner. Because shot-noise limits the phase sensitivity of all classical states, reduced noise in the average value for the observable being measured allows for improved phase sensitivity. However, additional phase sensitivity can be achieved using phase estimation strategies that account for the full distribution of measurement outcomes. Here we experimentally investigate a model of optical spin-squeezing, which uses post-selection and photon subtraction from the state generated using a parametric downconversion photon source, and we investigate the phase sensitivity of this model. The Fisher information for all photon-number outcomes shows it is possible to obtain a quantum advantage of 1.58 compared to the shot-noise value for five-photon events, even though due to experimental imperfection, the average noise for the relevant spin-observable does not achieve sub-shot-noise precision. Our demonstration implies improved performance of spin squeezing for applications to quantum metrology.
Measurements with quantum limited resolution have important applications in metrology and sensing, including atomic clocks, atom interferometry, and magnetometry. We perform a quantum-non-demolition measurement on a collective angular momentum of a million spin-4 Cs atoms with high optical depth in our work. Quantum mechanics limits the measurement's resolution to what is known as the standard quantum limit (SQL) when there is no entanglement between the individual atoms. We can generate entanglement between atoms to create spin squeezed states through quantum backaction, improving the measurement sensitivity by 5.5 dB relative to the SQL. We have recently rebuilt the entire experiment inside a state-of-the-art magnetic shield of mu-metal and aluminum. This upgrade has drastically mitigated classical control errors in the spin squeezing experiment. Furthermore, the ensemble's sensitivity to magnetic fields allows us to make precise measurements of the magnetic field environment. Using closed-loop feedback, we use our atomic magnetometer to measure magnetic fields 4.3 dB below the SQL. The shielded environment will allow us to optimize the magnetometer and sets the stage for future experiments to use the closed-loop control to explore more complicated quantum dynamics.