Energy-efficient healthcare systems are becoming increasingly critical for Industry 5.0 as the Internet of Medical Things (IoMT) expands, particularly with the integration of 5G technology. 5G-enabled IoMT systems allow real-time data collection, high-speed communication, and enhanced connectivity between medical devices and healthcare providers. However, these systems face energy consumption and data security challenges, especially with the growing number of connected devices operating in Industry 5.0 environments with limited power resources. Quantum computing integrated with machine learning (ML) algorithms, forming quantum machine learning (QML), offers exponential improvements in computational speed and efficiency through principles such as superposition and entanglement. In this paper, we propose and evaluate three QML algorithms, which are UU, variational UU, and UU-quantum neural networks (QNN) for classifying data from four different datasets: 5G-South Asia, Lumos5G 1.0, WUSTL EHMS 2020, and PS-IoT. Our comparative analysis, using various evaluation metrics, reveals that the UU-QNN method not only outperforms the other algorithms in the 5G-South Asia and WUSTL EHMS 2020 datasets, achieving 100% accuracy, but also aligns with the human-centric goals of Industry 5.0 by allowing more efficient and secure healthcare data processing. Furthermore, the robustness of the proposed quantum algorithms is verified against several noisy channels by analyzing accuracy variations in response to each noise model parameter, which contributes to the resilience aspect of Industry 5.0. These results offer promising quantum solutions for 5G-enabled IoMT healthcare systems by optimizing data classification and reducing power consumption while maintaining high levels of security even in noisy environments.
Energy-efficient healthcare systems are becoming increasingly critical for Industry 5.0 as the Internet of Medical Things (IoMT) expands, particularly with the integration of 5G technology. 5G-enabled IoMT systems allow real-time data collection, high-speed communication, and enhanced connectivity between medical devices and healthcare providers. However, these systems face energy consumption and data security challenges, especially with the growing number of connected devices operating in Industry 5.0 environments with limited power resources. Quantum computing integrated with machine learning (ML) algorithms, forming quantum machine learning (QML), offers exponential improvements in computational speed and efficiency through principles such as superposition and entanglement. In this paper, we propose and evaluate three QML algorithms, which are UU, variational UU, and UU-quantum neural networks (QNN) for classifying data from four different datasets: 5G-South Asia, Lumos5G 1.0, WUSTL EHMS 2020, and PS-IoT. Our comparative analysis, using various evaluation metrics, reveals that the UU-QNN method not only outperforms the other algorithms in the 5G-South Asia and WUSTL EHMS 2020 datasets, achieving 100% accuracy, but also aligns with the human-centric goals of Industry 5.0 by allowing more efficient and secure healthcare data processing. Furthermore, the robustness of the proposed quantum algorithms is verified against several noisy channels by analyzing accuracy variations in response to each noise model parameter, which contributes to the resilience aspect of Industry 5.0. These results offer promising quantum solutions for 5G-enabled IoMT healthcare systems by optimizing data classification and reducing power consumption while maintaining high levels of security even in noisy environments.
The healthcare industry is experiencing a significant digital transformation due to the proliferation of electronic health records, medical imaging technologies, wearable sensors, genomic sequencing, and Internet of Medical Things (IoMT) devices. These technologies produce enormous quantities of heterogeneous and high-dimensional data that hold valuable insights for disease diagnosis, prognosis, treatment planning and population health management. Conventional machine learning and deep learning methods have achieved significant success in extracting patterns from medical data, but their performance is increasingly limited by computational complexity, scalability limitations, and the increasing dimensionality of healthcare datasets. Quantum Machine Learning (QML) is a young interdisciplinary field, which integrates quantum computing with machine learning methods, and offers a promising way to overcome these challenges and enable more powerful intelligent healthcare systems.
The proliferation of large-scale Internet of Things (IoT) networks introduce significant challenges for real-time anomaly detection, particularly due to the massive volume, high speed, and heterogeneity of IoT-generated data. Traditional and deep learning-based models, while effective to some extent, often face computational bottlenecks that limit their scalability and responsiveness in complex IoT environments. To address these limitations, this paper investigates the application of Quantum Machine Learning (QML) for anomaly detection in IoT systems. By leveraging the parallelism and high-dimensional processing capabilities of quantum computing, QML offers a promising pathway to overcome current computational constraints. We propose a novel anomaly detection framework based on Quantum Generative Adversarial Networks (QGANs) designed to enhance security, reliability, and real-time responsiveness across diverse IoT scenarios, including smart homes, industrial IoT, healthcare monitoring, and critical infrastructure protection. Furthermore, this paper provides a comprehensive analysis of existing anomaly detection challenges, practical IoT applications, and outlines future research directions, including hybrid quantum-classical architectures, resource-efficient quantum algorithms for edge computing, and the integration of QML with emerging technologies to ensure scalable, secure, and robust IoT systems.
The growing volume of biomedical data from electronic health records, medical imaging, genomic sequencing, wearable Internet of Medical Things (IoMT) devices, and precision medicine has created new opportunities as well as significant computational challenges for healthcare. This chapter explores how Quantum Machine Learning (QML) can complement conventional machine learning by improving the analysis of complex, high-dimensional healthcare data through hybrid quantum–classical approaches. It introduces the fundamentals of quantum computing and discusses their application in genomics, medical imaging, drug discovery, IoMT-enabled healthcare, and cybersecurity. The chapter also presents an integrated framework that brings together quantum-enabled analytics, secure communication, and clinical decision support, while highlighting current challenges, ethical considerations, and future directions such as fault-tolerant quantum computing, explainable quantum AI, federated quantum learning, and post-quantum healthcare security.
Quantum Machine Learning (QML) has emerged as a transformative paradigm that integrates the computational advantages of quantum computing with the adaptive intelligence of machine learning to solve complex optimization problems in smart computing systems. Traditional optimization techniques often struggle with high-dimensional search spaces, combinatorial complexity, computational overhead, and scalability limitations in applications such as intelligent transportation, healthcare analytics, smart manufacturing, cybersecurity, cloud computing, and Internet of Things (IoT) infrastructures. QML approaches exploit quantum superposition, entanglement, and quantum parallelism to accelerate optimization tasks and enhance predictive performance beyond classical machine learning capabilities. This research proposes a hybrid Quantum Machine Learning optimization framework that combines Variational Quantum Circuits (VQCs), Quantum Neural Networks (QNNs), and classical deep learning models to address resource allocation, task scheduling, energy optimization, and intelligent decision-making in smart computing environments. The proposed framework integrates quantum-enhanced feature extraction, adaptive optimization layers, and reinforcement-based learning mechanisms to improve convergence speed and computational efficiency. Experimental analysis is performed using benchmark optimization datasets and simulated quantum environments to evaluate accuracy, execution time, energy efficiency, and scalability. Comparative results demonstrate that the proposed QML-based framework achieves superior optimization accuracy, reduced computational latency, and improved resource utilization when compared with traditional machine learning and classical metaheuristic optimization methods. Furthermore, the study highlights the practical significance of hybrid quantum-classical architectures in next-generation intelligent systems where large-scale optimization and real-time decision support are critical. The findings suggest that QML can significantly contribute to the advancement of sustainable, adaptive, and high-performance smart computing ecosystems while opening new directions for future quantum-aware intelligent infrastructures.
The Internet of Medical Things (IoMT) provides the capabilities of continuous real-time monitoring of patients using connected devices as well as generating a great deal of healthcare data; these are the benefits of IoMT. According to multiple sources, machine learning (ML) and deep learning (DL) have been used in the medical field for many years, and there are also issues surrounding these technologies that impact their ability to support clinical decision-making. These include issues related to scalability, interoperability, latency, explainability of the model output, and cybersecurity (WHO, 2021; Esteva et al., 2019; Topol et al., 2019). In this chapter, a hybrid classical-quantum framework is proposed for use in real-time patient monitoring, which integrates Quantum Intelligence (QI), Quantum ML (QML), Edge Computing (EC), and the IoMT. In addition, the authors provide examples of current use cases as well as practical recommendations to support the adoption of secure, scalable, and intelligent healthcare monitoring systems.
The emergence of 5G networks has revolutionized healthcare delivery by enabling communication with ultra-low latency, massive connectivity, and quick access to IoT devices' medical data. The digitalization of healthcare has, however, introduced privacy, data security, and scalability as major challenges, and the issues have been worsened by the rapid digitalization of the healthcare industry. The current review paper is a comprehensive evaluation of the role of Quantum Machine Learning (QML) as a paradigm for data handling with privacy preserved in the healthcare ecosystems supported by 5G. It collects advancements in quantum cryptography, Quantum Key Distribution (QKD), federated learning, and blockchain technology to explore how the combining of such technologies will enhance the confidentiality, interoperability, and real-time decision-making of the data. The review arranges and compares the state-of-theart research of 2019-2025, in which the trends, architectures, and security protocols that link classical and quantum methods in healthcare analytics become visible. It also addresses the main hurdles like quantum hardware limitations, interoperability gaps, and the tuning of federated models, and it indicates potential future research paths for the development of healthcare infrastructure that is scalable, reliable, and quantum-resistant. In conclusion, this paper gives a thorough understanding of how quantum intelligence can alter the data security and privacy landscape in 5G-enabled smart healthcare systems.