The emergence of 5G networks has revolutionized healthcare delivery by enabling communication with ultra-low latency, massive connectivity, and quick access to IoT devices' medical data. The digitalization of healthcare has, however, introduced privacy, data security, and scalability as major challenges, and the issues have been worsened by the rapid digitalization of the healthcare industry. The current review paper is a comprehensive evaluation of the role of Quantum Machine Learning (QML) as a paradigm for data handling with privacy preserved in the healthcare ecosystems supported by 5G. It collects advancements in quantum cryptography, Quantum Key Distribution (QKD), federated learning, and blockchain technology to explore how the combining of such technologies will enhance the confidentiality, interoperability, and real-time decision-making of the data. The review arranges and compares the state-of-theart research of 2019-2025, in which the trends, architectures, and security protocols that link classical and quantum methods in healthcare analytics become visible. It also addresses the main hurdles like quantum hardware limitations, interoperability gaps, and the tuning of federated models, and it indicates potential future research paths for the development of healthcare infrastructure that is scalable, reliable, and quantum-resistant. In conclusion, this paper gives a thorough understanding of how quantum intelligence can alter the data security and privacy landscape in 5G-enabled smart healthcare systems.
The emergence of 5G networks has revolutionized healthcare delivery by enabling communication with ultra-low latency, massive connectivity, and quick access to IoT devices' medical data. The digitalization of healthcare has, however, introduced privacy, data security, and scalability as major challenges, and the issues have been worsened by the rapid digitalization of the healthcare industry. The current review paper is a comprehensive evaluation of the role of Quantum Machine Learning (QML) as a paradigm for data handling with privacy preserved in the healthcare ecosystems supported by 5G. It collects advancements in quantum cryptography, Quantum Key Distribution (QKD), federated learning, and blockchain technology to explore how the combining of such technologies will enhance the confidentiality, interoperability, and real-time decision-making of the data. The review arranges and compares the state-of-theart research of 2019-2025, in which the trends, architectures, and security protocols that link classical and quantum methods in healthcare analytics become visible. It also addresses the main hurdles like quantum hardware limitations, interoperability gaps, and the tuning of federated models, and it indicates potential future research paths for the development of healthcare infrastructure that is scalable, reliable, and quantum-resistant. In conclusion, this paper gives a thorough understanding of how quantum intelligence can alter the data security and privacy landscape in 5G-enabled smart healthcare systems.
Secure, privacy-preserving sharing and analysis of health data is foundational to precision medicine, population health, and telehealth services. Emerging quantum networks promise fundamentally new communication primitives (entanglement, quantum key distribution) that when integrated with advanced AI architectures can enable end-to-end secure healthcare systems with improved confidentiality, tamper resistance, and novel distributed computation modes. This article develops a systematic framework for integrating quantum communications and cryptography with classical and hybrid quantum–classical AI models in healthcare. We (a) summarize the enabling quantum network technologies and AI building blocks, (b) propose layered system architectures and protocols for secure data exchange and collaborative learning, (c) formalize threat models and privacy requirements in healthcare contexts, (d) discuss algorithmic integrations (federated learning with QKD, quantum-enhanced machine learning, secure multiparty quantum protocols), (e) provide evaluation metrics and prototype deployment roadmaps, and (f) identify research gaps and regulatory implications. The treatment is scholarly yet practical, aimed at researchers, engineers, and healthcare stakeholders planning future-proof secure AI systems. (Keywords: quantum networks; quantum key distribution; quantum machine learning; federated learning; healthcare security; privacy.)
The advent of Quantum Key Distribution (QKD) and quantum-based privacy-preserving techniques has ushered in a new era for securing communication channels within the Internet of Medical Things (IoMT) systems. We examine the fundamentals, uses, and ramifications of quantum cryptography in relation to healthcare data security in this thorough investigation. The journey commences with an in-depth overview of quantum cryptography, unraveling the concepts of superposition, entanglement, and quantum gates that form the bedrock of quantum computing. As we proceed, we investigate the uses of quantum cryptography, highlighting its contribution to resolving the particular issues brought about by the data-intensive and networked character of IoMT systems. The relevance of QKD in ensuring secure communication within IoMT is meticulously dissected, with case studies and experiments demonstrating the practicality and effectiveness of quantum-based privacy-preserving techniques. From telemedicine networks to wearable health devices, each case study offers valuable insights into the application of quantum-safe cryptography, showcasing its ability to fortify data integrity and confidentiality. A meticulous survey of existing research, coupled with an analysis of advancements in quantum cryptography, provides a panoramic view of the current landscape. From hardware limitations to distance constraints, the study navigates through challenges and breakthroughs, offering a roadmap for the future integration of quantum technologies into IoMT systems.Comparing quantum-based approaches with classical cryptography unveils a nuanced landscape of computational complexity, key distribution methodologies, and real-time encryption considerations. This comparative analysis serves as a guide for healthcare practitioners and technologists in making informed decisions regarding the adoption of quantum-based privacy-preserving techniques in IoMT environments. The case studies and experiments collectively paint a picture of the practicality and promise of quantum-based privacy-preserving techniques in IoMT scenarios. Anticipating future advancements, the exploration extends into quantum hardware improvements, standardization efforts, and the integration of quantum technologies with emerging trends like edge computing and blockchain. As the healthcare industry stands on the cusp of a quantum revolution, the comprehensive insights provided herein offer a foundation for understanding, implementing, and shaping the future of secure healthcare communication through the lens of quantum cryptography.
The increasing availability of electronic health records, medical imaging databases, and sensor-generated clinical datasets has boosted the need for privacy-preserving yet scalable analytical frameworks. In this regard, quantum computing and federated learning are becoming two focal points that may significantly shape future healthcare data processing. Quantum computing provides powerful tools for working with complex, high-dimensional optimization and learning problems, while federated learning facilitates collaborative model training without requiring the centralized exchange of sensitive information about patients. This review explores the integration of these two technologies and Quantum Split Federated Learning (QSFL) as a promising approach for secure and scalable co-operative health care analytics. The treatment then turns to discuss the quantum computation mathematical and algorithmic basics, and subsequently, quantum machine learning methods based on extremes of supervised, unsupervised, and semi-supervised modes. Special emphasis is placed on how QSFL can enable privacy-aware inter-institutional learning and enhance clinical decision support systems. It also surveys the applications for creating high-quality synthetic medical data sets for training, validation and data-sharing using quantum generative adversarial networks (qGANs). In addition to the technological opportunities this paper critically evaluates the practical challenges to real-world implementation, such as hardware limitations, communication costs, regulatory matters, and ethical considerations of a distributed medical learning system-based infrastructure and mechanism. In the end, the survey identifies important open research problems and provides suggestions for future research directions towards realizing quantum-enabled, privacy-preserving healthcare intelligence systems that are anticipated to usher in a new era of medical analytics.
The convergence of quantum computing and artificial intelligence is creating new opportunities for smart healthcare, particularly in medical image analysis, privacy-preserving data management, and clinical decision support. This chapter presents a conceptual and architectural overview of quantum machine learning (QML) for a multidisciplinary audience. It introduces quantum computing fundamentals and discusses quantum kernel methods and variational quantum circuits using the MedMNIST benchmark. A geometric separation diagnostic is proposed as a conceptual, computationally inexpensive, hardware-independent screening construct for indicating whether quantum encoding places data in a label-separable configuration, with its empirical validation identified as future work. The chapter further examines privacy-preserving healthcare through federated learning, synthetic data governance, differential privacy, post-quantum cryptography, and regulatory considerations, and presents a five-layer quantum-enhanced healthcare architecture together with key challenges and future research directions.
The growing digitalization of medical diagnostics has resulted in massive amounts of complicated data, including medical imaging and genomic sequences, clinical writing and real-time patient monitoring. Classical machine learning (CML) has achieved amazing success in evaluating such data. But its computational restrictions hinder scalability and efficiency when dealing with high-dimensional biomedical problems. Quantum machine learning (QML) combines the principles of quantum computing (QC) with advanced learning algorithms to offer a transformative paradigm for digital healthcare. This paper provides a systematic overview of QML foundations including quantum data encoding (QDC), variational quantum circuits (VQC), kernel methods, and hybrid quantum classical models. This paper also focuses on their applications in medical imaging, genomics, natural language processing (NLP) for electronic health records, drug discovery and healthcare security. We present comparative insights between classical and quantum approaches such as slow processing of high-dimensional data, limited scalability and inefficiency in complex optimization problems. This review also emphasizes the emerging directions towards quantum-based personalized digital healthcare approaches. By combining medical science with quantum QML has the potential to revolutionize the future of precision diagnostics, treatment optimization and healthcare data security. This study also provides a valuable resource for those interested in quantum computing and researchers who want to stay updated on the fast-growing area.
Quantum machine learning (QML) has emerged as a transformative paradigm that leverages quantum mechanical phenomena superposition, entanglement, and quantum interference to enhance computational approaches in healthcare. This comprehensive survey systematically examines advances in QML for healthcare applications from 2020 to 2025, analyzing cutting-edge algorithms, recent implementations, and emerging prospects across drug discovery, medical imaging, genomics, and clinical decision support. We review Quantum Support Vector Machines (QSVM), Variational Quantum Circuits (VQC), Quantum Neural Networks (QNN), and hybrid quantum-classical frameworks. Our analysis of 150+ recent publications reveals significant theoretical progress alongside persistent hardware constraints and algorithmic challenges. We provide a comprehensive taxonomy of QML algorithms, a comparative performance analysis against classical baselines, a detailed examination of NISQ-era limitations, and a technology roadmap spanning near-term hybrid approaches through long-term fault-tolerant quantum computing. This survey serves as an updated reference for researchers and practitioners navigating the rapidly evolving intersection of quantum computing and medical informatics.