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arXiv:2504.06892 · International Conference on Quantum Communications, Networking, and Computing (QCNC)

Applications of Hybrid Machine Learning Methods to Large Datasets: A Case Study

Georgios Maragkopoulos, Nikos Stefanakos, Aikaterini Mandilara, Dimitris Syvridis

Published Mar 31, 2025• 1 citation
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Abstract

We combine classical and quantum Machine Learning (ML) techniques to effectively analyze long time-series data acquired during experiments. Specifically, we demonstrate that replacing a deep classical neural network with a thoughtfully designed Variational Quantum Circuit (VQC) in an ML pipeline for multiclass classification of time-series data yields the same classification performance, while significantly reducing the number of trainable parameters. To achieve this, we use a VQC based on a single qudit, and encode the classical data into the VQC via a trainable hybrid autoencoder which has been recently proposed as embedding technique. Our results highlight the importance of tailored data pre-processing for the circuit and show the potential of qudit-based VQCs.

DOI
10.1109/qcnc64685.2025.00114

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We combine classical and quantum Machine Learning (ML) techniques to effectively analyze long time-series data acquired during experiments. Specifically, we demonstrate that replacing a deep classical neural network with a thoughtfully designed Variational Quantum Circuit (VQC) in an ML pipeline for multiclass classification of time-series data yields the same classification performance, while significantly reducing the number of trainable parameters. To achieve this, we use a VQC based on a single qudit, and encode the classical data into the VQC via a trainable hybrid autoencoder which has been recently proposed as embedding technique. Our results highlight the importance of tailored data pre-processing for the circuit and show the potential of qudit-based VQCs.
Abstract Variational quantum circuits (VQC) lie at the forefront of quantum machine learning research. Still, the use of quantum networks for real data processing remains challenging as the number of available qubits cannot accommodate a large dimensionality of data—if the usual angle encoding scenario is used. To achieve dimensionality reduction, Principal Component Analysis is routinely applied as a pre-processing method before the embedding of the classical features on qubits. In this work, we propose an alternative method which reduces the dimensionality of a given dataset by taking into account the specific quantum embedding that comes after. This method aspires to make quantum machine learning with VQCs more versatile and effective on datasets of high dimension. At a second step, we propose a quantum-inspired classical autoencoder model which can be used to encode information in low latent spaces. The power of our proposed models is exhibited via numerical tests. We show that our targeted dimensionality reduction method considerably boosts VQC’s performance, and we also identify cases for which the second model outperforms classical autoencoders in terms of reconstruction loss.
Abstract Today, classification is a significant task in data science, and many industries, including healthcare, transport, and banking sectors, are required to classify the data. In this NISQ era, quantum computers are capable of solving complex data challenges and can predict results with minimum features. The quantum neural network is being studied extensively for machine learning problems. In this paper, we have performed the multiclass classification using variational quantum circuits on benchmark datasets. A combination of quantum and classical neural networks is used to build the quantum circuit and optimize the parameters. The quantum circuit is used for the feedforward architecture, while in back-propagation, parameters are updated using a classical optimizer on classical computers. We have successfully shown classification using the proposed approach in benchmark datasets, such as the Iris flower and the MNIST Digit data set. Our results show that VQC is a promising candidate for classification problems with fewer features. To perform our experiments we have used IBM Quantum hardware and simulators.
Heart disease is one of the major global causes of death, requiring early and precise detection for efficient treatment.With advancements in quantum computing, Variational Quantum Circuits (VQCs) have gained recognition as a valuable technique for improving learning models in medical diagnosis.This study further explores the application of VQC-based models for heart disease prediction, leveraging quantum computing to enhance classification accuracy.A hybrid quantum-classical model has been developed, which combines classical preprocessing for feature extraction from patient datasets with a VQC-based classifier for medical predictions.The quantum circuit using variational parameters is optimized to reduce the loss function and facilitate effective learning from complex medical data.This proposed approach is tested on benchmark heart disease datasets and evaluated against classical Machine Learning (ML) models, including Support Vector Machines (SVMs), Random Forests, and Neural Networks.The experimental results show that VQC-based models achieve high accuracy and outperform classical models, notably on high-dimensional, non-linearly separable data.The quantum advantage of VQCs lies in their ability to encode and process data in a huge Hilbert space.However, challenges such as noise in near-term quantum devices and scalability issues remain key.This research underscores the efficacy of VQCbased quantum machine learning in medical diagnosis, paving the way for future studies on quantum-enhanced healthcare solutions.Further advancements in quantum hardware and hybrid learning techniques could allow quantum-assisted heart disease prediction to become an effective clinical tool.
Multiclass classification is of great interest for various applications, for example, it is a common task in computer vision, where one needs to categorize an image into three or more classes. Here we propose a quantum machine learning approach based on quantum convolutional neural networks for solving the multiclass classification problem. The corresponding learning procedure is implemented via TensorFlowQuantum as a hybrid quantum-classical (variational) model, where quantum output results are fed to the softmax activation function with the subsequent minimization of the cross entropy loss via optimizing the parameters of the quantum circuit. Our conceptional improvements here include a new model for a quantum perceptron and an optimized structure of the quantum circuit. We use the proposed approach to solve a 4-class classification problem for the case of the MNIST dataset using eight qubits for data encoding and four ancilla qubits; previous results have been obtained for 3-class classification problems. Our results show that the accuracy of our solution is similar to classical convolutional neural networks with comparable numbers of trainable parameters. We expect that our findings will provide a new step toward the use of quantum neural networks for solving relevant problems in the NISQ era and beyond.
Abstract Quantum Machine Learning (QML) is a promising field that combines the power of quantum computing with machine learning. Variational quantum circuits, where parameters of circuits are learned classically, have been widely used in many recent applications of QML. This is an instance of a hybrid quantum-classical framework, where both classical and quantum components are present. However, applying these techniques to applications involving massive data is a challenging task. One way to overcome this, is using the concept of classical-quantum transfer learning with the help of dressed quantum circuit, introduced recently, where the underlying neural architecture is pre-trained classically, but at the final steps (decision layer), a quantum circuit is used, followed by quantum measurements and post-processing to classify images with high precision. In this paper, we applied hybrid classical-quantum transfer learning to another task of massive data processing, i.e. Natural Language Processing (NLP). We show how to (binary) classify short texts (e.g., SMS) with classical-quantum transfer learning, which was originally applied to image processing only. Our quantum network was pre-trained by Bidirectional Encoder Representations from the Transformers (BERT) model, and its variational quantum circuit is fine-tuned for text processing. We evaluated the performance of our hybrid neural architecture using the Receiver Operating Characteristic (ROC) curve, which is typically used in the evaluation of classification problems. The results indicate high precision as well as lower loss function. To our knowledge, our work is the first application of quantum transfer learning to the area of NLP. Finally a comparison with a tool that uses learning but in a different way than transfer learning is presented
Deep learning is one of the most successful and far-reaching strategies used in machine learning today. However, the scale and utility of neural networks is still greatly limited by the current hardware used to train them. These concerns have become increasingly pressing as conventional computers quickly approach physical limitations that will slow performance improvements in years to come. For these reasons, scientists have begun to explore alternative computing platforms, like quantum computers, for training neural networks. In recent years, variational quantum circuits have emerged as one of the most successful approaches to quantum deep learning on noisy intermediate scale quantum devices. We propose a hybrid quantum-classical neural network architecture where each neuron is a variational quantum circuit. We empirically analyze the performance of this hybrid neural network on a series of binary classification data sets using a simulated universal quantum computer and a state of the art universal quantum computer. On simulated hardware, we observe that the hybrid neural network achieves roughly 10% higher classification accuracy and 20% better minimization of cost than an individual variational quantum circuit. On quantum hardware, we observe that each model only performs well when the qubit and gate count is sufficiently small.