Parameterized Quantum Circuits (PQC) have obtained increasing popularity thanks to their great potential for near-term Noisy Intermediate-Scale Quantum (NISQ) computers. Achieving quantum advantages usually requires a large number of qubits and quantum circuits with enough capacity. However, limited coherence time and massive quantum noises severely constrain the size of quantum circuits that can be executed reliably on real machines. To address these two pain points, we propose QuantumSEA, an in-time sparse exploration for noise-adaptive quantum circuits, aiming to achieve two key objectives: (1) implicit circuits capacity during training - by dynamically exploring the circuit's sparse connectivity and sticking a fixed small number of quantum gates throughout the training which satisfies the coherence time and enjoy light noises, enabling feasible executions on real quantum devices; (2) noise robustness - by jointly optimizing the topology and parameters of quantum circuits under real device noise models. In each update step of sparsity, we leverage the moving average of historical gradients to grow necessary gates and utilize salience-based pruning to eliminate insignificant gates. Extensive experiments are conducted with 7 Quantum Machine Learning (QML) and Variational Quantum Eigensolver (VQE) benchmarks on 6 simulated or real quantum computers, where QuantumSEA consistently surpasses noise-aware search, human-designed, and randomly generated quantum circuit baselines by a clear performance margin. For example, even in the most challenging on-chip training regime, our method establishes state-of-the-art results with only half the number of quantum gates and ~ 2 ×time saving of circuit executions. Codes are available at https://github.com/VITA-Group/QuantumSEA.
Parameterized Quantum Circuits (PQC) have obtained increasing popularity thanks to their great potential for near-term Noisy Intermediate-Scale Quantum (NISQ) computers. Achieving quantum advantages usually requires a large number of qubits and quantum circuits with enough capacity. However, limited coherence time and massive quantum noises severely constrain the size of quantum circuits that can be executed reliably on real machines. To address these two pain points, we propose QuantumSEA, an in-time sparse exploration for noise-adaptive quantum circuits, aiming to achieve two key objectives: (1) implicit circuits capacity during training - by dynamically exploring the circuit's sparse connectivity and sticking a fixed small number of quantum gates throughout the training which satisfies the coherence time and enjoy light noises, enabling feasible executions on real quantum devices; (2) noise robustness - by jointly optimizing the topology and parameters of quantum circuits under real device noise models. In each update step of sparsity, we leverage the moving average of historical gradients to grow necessary gates and utilize salience-based pruning to eliminate insignificant gates. Extensive experiments are conducted with 7 Quantum Machine Learning (QML) and Variational Quantum Eigensolver (VQE) benchmarks on 6 simulated or real quantum computers, where QuantumSEA consistently surpasses noise-aware search, human-designed, and randomly generated quantum circuit baselines by a clear performance margin. For example, even in the most challenging on-chip training regime, our method establishes state-of-the-art results with only half the number of quantum gates and ~ 2 ×time saving of circuit executions. Codes are available at https://github.com/VITA-Group/QuantumSEA.
Quantum noise is the key challenge in Noisy Intermediate-Scale Quantum (NISQ) computers. Previous work for mitigating noise has primarily focused on gate-level or pulse-level noise-adaptive compilation. However, limited research has explored a higher level of optimization by making the quantum circuits themselves resilient to noise.In this paper, we propose QuantumNAS, a comprehensive framework for noise-adaptive co-search of the variational circuit and qubit mapping. Variational quantum circuits are a promising approach for constructing quantum neural networks for machine learning and variational ansatzes for quantum simulation. However, finding the best variational circuit and its optimal parameters is challenging due to the large design space and parameter training cost. We propose to decouple the circuit search from parameter training by introducing a novel SuperCircuit. The SuperCircuit is constructed with multiple layers of pre-defined parameterized gates (e.g., U3 and CU3) and trained by iteratively sampling and updating the parameter subsets (SubCircuits) of it. It provides an accurate estimation of SubCircuits performance trained from scratch. Then we perform an evolutionary co-search of SubCircuit and its qubit mapping. The SubCircuit performance is estimated with parameters inherited from SuperCircuit and simulated with real device noise models. Finally, we perform iterative gate pruning and finetuning to remove redundant gates in a fine-grained manner.Extensively evaluated with 12 quantum machine learning (QML) and variational quantum eigensolver (VQE) benchmarks on 14 quantum computers, QuantumNAS significantly outperforms noise-unaware search, human, random, and existing noise-adaptive qubit mapping baselines. For QML tasks, QuantumNAS is the first to demonstrate over 95% 2-class, 85% 4-class, and 32% 10-class classification accuracy on real quantum computers. It also achieves the lowest eigenvalue for VQE tasks on H2, H2O, LiH, CH4, BeH2compared with UCCSD baselines. We also open-source the TorchQuantum library for fast training of parameterized quantum circuits to facilitate future research.
Designing parameterized quantum circuits (PQCs) that are expressive, trainable, and robust to hardware noise is a central challenge for quantum machine learning (QML) on noisy intermediate-scale quantum (NISQ) devices. We present a Domain-Aware Quantum Circuit (DAQC) that leverages image priors to guide locality-preserving encoding and entanglement via non-overlapping DCT-style zigzag windows. The design employs interleaved encode-entangle-train cycles, where entanglement is applied among qubits hosting neighboring pixels, aligned to device connectivity. This staged, locality-preserving information flow expands the effective receptive field without deep global mixing, enabling efficient use of limited depth and qubits. The design concentrates representational capacity on short-range correlations, reduces long-range two-qubit operations, and encourages stable optimization, thereby mitigating depth-induced and globally entangled barren-plateau effects. We evaluate DAQC on MNIST, FashionMNIST, and PneumoniaMNIST datasets. On quantum hardware, DAQC achieves performance competitive with strong classical baselines (e.g., ResNet-18/50, DenseNet-121, EfficientNet-B0) and substantially outperforming Quantum Circuit Search (QCS) baselines. To the best of our knowledge, DAQC, which uses a quantum feature extractor with only a linear classical readout (no deep classical backbone), currently achieves the best reported performance on real quantum hardware for QML-based image classification tasks. Code and pretrained models are available at: https://github.com/gurinder-hub/DAQC.
Noisy Intermediate-Scale Quantum (NISQ) devices are promising platforms for practical quantum computing, but their performance is significantly affected by limited qubit availability, gate errors, decoherence, circuit depth, and hardware-dependent noise. Conventional quantum circuits are generally designed and optimized before execution and may not respond effectively to changing hardware conditions during computation. This research proposes a Self-Adaptive Quantum Circuit framework that dynamically modifies quantum circuits according to the current computational resources and noise characteristics of NISQ devices. The proposed framework monitors parameters such as qubit fidelity, gate error rates, circuit depth, execution time, and resource availability, and automatically selects suitable circuit configurations to improve computational performance. Adaptive mechanisms can be employed to reduce unnecessary gates, optimize qubit utilization, and mitigate the impact of hardware noise while maintaining the required computational accuracy. The framework will be evaluated using simulation platforms and available NISQ quantum hardware, comparing adaptive circuits with conventional static circuits using metrics such as accuracy, fidelity, circuit depth, gate count, execution time, and error rate. The expected outcome is a resource-efficient and noise-aware quantum circuit optimization approach capable of improving the reliability and performance of quantum applications on near-term quantum hardware. The proposed research aims to contribute toward more practical, flexible, and hardware-aware quantum computing systems for NISQ-era applications. Keywords: NISQ Computing, Self-Adaptive Quantum Circuits, Quantum Circuit Optimization, Quantum Error Mitigation, Quantum Noise, Quantum Computing.
Quantum Neural Networks (QNNs) based on parameterized quantum circuits (PQCs) are gaining significant research attention due to their potential to achieve quantum advantages on Near-Term Noisy Intermediate-Scale Quantum (NISQ) computers. However, executing QNNs on NISQ devices is challenging due to quantum noise. To address this, we propose a noise-resilient QNN (NR-QNN) that leverages the unique characteristics of PQCs to perform noise-aware optimizations during the inference stage of QNNs. Specifically, NR-QNN employs two optimization techniques to mitigate the impact of noise on QNNs: quantum pruning and sensitivity-aware qubit mapping. The first technique is quantum pruning which identifies gates with small angle of rotations and removes them to simplify circuit of QNNs. The second optimization technique is sensitivity-aware qubit mapping which maps more important logical qubits to more reliable physical qubits. This technique is based on the observation that there can be variation in the sensitivity of an output to input qubits in a QNN. NR-QNN exploits this variability and guides qubit allocation to use reliable physical qubits for sensitive logical qubits. Our evaluation on a real quantum computer demonstrates that NR-QNN enhances the robustness of QNNs, enabling them to operate effectively on NISQ devices.
The rapid advancement in Quantum Computing, particularly through Noisy-Intermediate Scale Quantum (NISQ) devices, has spurred significant interest in Quantum Machine Learning (QML) applications. Despite their potential, fully-quantum algorithms remain impractical due to the limitations of current NISQ devices. Hybrid quantum-classical neural networks (HQNNs) have emerged as a viable alternative, leveraging both quantum and classical computations to enhance machine learning capabilities. However, the constrained resources of NISQ devices, particularly the limited number of qubits, pose significant challenges for executing large-scale quantum circuits. This work addresses these current challenges by proposing a novel and practical methodology for quantum circuit cutting of HQNNs, allowing large quantum circuits to be executed on limited-qubit NISQ devices. Our approach not only preserves the accuracy of the original circuits but also supports the training of quantum parameters across all subcircuits, which is crucial for the learning process in HQNNs. We propose a cutting methodology for HQNNs that employs a greedy algorithm for identifying efficient cutting points, and the implementation of trainable subcircuits, all designed to maximize the utility of NISQ devices in HQNNs. The findings suggest that quantum circuit cutting is a promising technique for advancing QML on current quantum hardware, since the cut circuit achieves comparable accuracy and much lower qubit requirements than the original circuit. The code is available at https://github.com/eBrain4Everyone/QNN-Cutting.
Adaptive quantum machine learning (QML) represents an exciting frontier at the intersection of quantum computing and classical bio-inspired optimization. The constraints of noisy intermediate-scale quantum (NISQ) devices—limited qubit counts, significant decoherence, and measurement uncertainties—pose formidable challenges to training parameterized quantum circuits (PQCs) using traditional gradient-based methods. To overcome these hurdles, we propose a novel Adaptive PSO–QML framework that integrates a particle swarm optimization (PSO)–inspired algorithm with dynamic hyperparameter adjustment, enabling real-time tuning of PQC parameters based on performance feedback. Unlike static optimizers, our approach continuously adapts its inertia weight and cognitive/social coefficients to balance exploration and exploitation, responding to stagnation or rapid improvement in measured fitness. We evaluate this hybrid algorithm on two benchmark classification tasks: the classical Iris dataset encoded into a 2-qubit circuit and a quantum-encoded subset of the MNIST dataset on 4 qubits. Our experiments, conducted on the Qiskit Aer simulator under realistic noise models (depolarizing, amplitude damping, and mixed), demonstrate that Adaptive PSO–QML achieves an average accuracy improvement of 12% over fixed-parameter PSO and 15% over Adam-based gradient descent, with p-values below 0.01 across paired t-tests. Statistical analysis summarized in Table 1 confirms the significance of these gains. Detailed simulation research further reveals that the adaptive mechanism not only accelerates convergence by approximately 30%—reducing total circuit evaluations—but also exhibits robust performance across varying circuit depths (1–3 entangling layers) and noise intensities. Our findings suggest that bio-inspired adaptation is a powerful tool for mitigating barren plateaus and noise effects in NISQ-era QML, paving the way for scalable quantum advantage in near-term hardware.