The Darwinian paradigm of biological evolution is based on the separability of the variation and selection processes. As a result, the population thinking had always been an integral part of the Darwinian approach. I propose an alternative scheme of biological adaptation. It is based on appreciation of limits of what we can observe considering an individual biological object. This leads to a possibility for the adaptation process to occur on the level of a single object, as a 'selection among virtual states of the organism'. I discuss the application of this idea to the phenomenon of adaptive mutations in bacteria.
The Darwinian paradigm of biological evolution is based on the separability of the variation and selection processes. As a result, the population thinking had always been an integral part of the Darwinian approach. I propose an alternative scheme of biological adaptation. It is based on appreciation of limits of what we can observe considering an individual biological object. This leads to a possibility for the adaptation process to occur on the level of a single object, as a 'selection among virtual states of the organism'. I discuss the application of this idea to the phenomenon of adaptive mutations in bacteria.
I compare two quantum-theoretical approaches to the phenomenon of adaptive mutations, termed here Q-cell and Q-genome. I use 'fluctuation trapping' model as a general framework. I introduce notions of R-error and D-error and argue that the 'fluctuation trapping' model has to employ a correlation between the R- and D- errors. Further, I compare how the two approaches can justify the R-D-error correlation, focusing on the advantages of the Q-cell approach. The positive role of environmentally induced decoherence (EID) on both steps of the adaptation process is emphasized. A starving bacterial cell is proposed to be in an einselected state. The intracellular dynamics in this state has a unitary character and I propose to interpret it as 'exponential growth in imaginary time', analogously to the commonly considered 'diffusion' interpretation of the Schroedinger equation. Addition of a substrate leads to Wick rotation and a switch from 'imaginary time' reproduction to a 'real time' reproduction regime. Due to the variations at the genomic level (such as base tautomery), the starving cell has to be represented as a superposition of different components, all 'reproducing in imaginary time'. Adidtion of a selective substrate, allowing only one of these components to amplify, will cause Wick rotation and amplification of this component, thus justifying the occurence of the R-D-error correlation. Further ramifications of the proposed ideas for evolutionary theory are discussed.
Zurek’s “quantum Darwinism” and its translation into the evolution of adaptive systems In this work I justify a scheme that favors a non-reductive integration between physical and biological approaches based on the notion of information as interpretation. I start with a discussion on the cross fertilization and feedbacks between physics and biology for it helps to explain Maxwells demon metaphor as a forerunner of a notion of information applicable to the problem of biological adaptation that is best conceived today as information gathering and using systems (IGUS) in the sense of Zurek. It is shown how IGUS by means of measurements generate informative correlations between micro-states (genotype) and macro-states (phenotype), and between macro-states (phenotype) and environment. I further examine Zureks decoherence theory dubbed “quantum Darwinism” according to which the environment eliminates most of the superpositions of quantum systems leaving only a set of preferred states, among which are chosen those that are in fact realized in the classical world. In this view IGUS are equated to non-conscious agents of quantum measurement, a posture that modifies Copenhagen interpretation without falling into the difficulties of the “many worlds” interpretation. I, thus, propose that in order to tackle the problem of biological adaptation, it would be important to understand information as IGUS’ interpretative activity thought as physical and/or biological systems that actualize an organizing potential in accordance to an “internal model” of systems environment interactions, so that they interpret physical perturbations as informative signals that orient structural adjustments to be adopted and the actions that are projected to the external milieu. To end up I show how this model may serve to account for the origin of adaptive mutations in bacteria and to formally describe developing epigenetic systems. In this way the classical debate between Lamarckian and Darwinian schools must be reframed and perhaps superseded as the new scheme of interpretation is validated with more experimental evidence. To conclude I argue that semiosis is the clue to justify the deep analogy that allows to establishing bidirectional bridges between physical and biological models of adaptive evolution. key words. Quantum Darwinism, Neo-Lamarckism, natural selection, information, IGUS, adaptation, coherence, superposition, entanglement, sign, observer, measurement, ci Copenhagen interpretation, many worlds interpretation, epigenetics.
• Published in PLOS One, reinterpreting DNA not as classical chemical bonds but as an open quantum system continuously interacting with the external environment. • Presents a theoretical framework where quantum tunneling, wave functions, and macroscopic quantum entanglement regulate the directionality of genetic mutations and increase survival fitness under environmental stress. • An innovative model demonstrating that genetic evolution is not driven by simple random chemical variations, but by a highly synchronized quantum mechanical probability distribution system within the cell. [Quantum Biology Society] Since Charles Darwin, the evolution of living organisms has been explained within the classical biological framework of random mutation and natural selection. However, a groundbreaking study has recently been published that reinterprets the mechanisms of genetic information preservation and evolution beyond the perspective of classical chemical bonds into subatomic quantum physics, delivering a fresh shock to the academic community. A paper titled "DNA as a quantum system in evolution," published in the March 2026 issue of the international journal PLOS One, identified DNA not merely as an information storage medium but as an open quantum system continuously communicating with the environment. Researcher Nahuel Aquiles Garcia, who conducted this single-author study, newly analyzed DNA dynamics through a quantum-informational model, presenting groundbreaking insights into the evolutionary process of living organisms. ■ An Open Quantum System Communicating with the Environment The researcher explained that DNA, the genetic material of living organisms, functions not as an isolated chemical molecule but as an open quantum system constantly interacting with minute energy changes in the external environment. According to this framework, changes in the minute wave function, quantum tunneling, and macroscopic quantum entanglement phenomena occurring within DNA directly affect the genetic behavior of living organisms. ■ Directionality of Mutations Beyond Randomness The most interesting part is the redefinition of how genetic mutations occur under environmental stress. From the existing Darwinian perspective, mutations were considered the result of blind and random chemical errors. However, the new quantum biological model suggests that the complex energy fields within the cell and the highly synchronized quantum mechanical probability distribution system between molecules can specifically regulate the directionality of mutations. In other words, quantum phenomena can microscopically guide evolutionary pressure in a direction that increases the survival fitness of the organism. ■ A New Paradigm in Evolutionary Biology This study is a bold and innovative biophysical achievement demonstrating that genetic evolution might not simply be the product of blind chance, but an elegant process fundamentally driven and orchestrated by the laws of quantum physics. This new paradigm, which integrates classical biology and quantum mechanics in unlocking the secrets of the origin and evolution of life, is expected to open completely new horizons of research across genetics and the life sciences in the future.
The Darwinian nature of Wojciech Zurek's theory of Quantum Darwinism is evaluated against the criteria of a Darwinian process as understood within Universal Darwinism. The characteristics of a Darwinian process are developed including the consequences of accumulated adaptations resulting in adaptive systems operating in accordance with Friston's free energy principle and employing environmental simulations. Quantum theory, as developed in Zurek's research program and encapsulated by his theory of Quantum Darwinism is discussed from the view that Zurek's derivation of the measurement axioms implies that the evolution of a quantum system entangled with environmental entities is determined solely by the nature of the entangled system. There need be no further logical foundation. Quantum Darwinism is found to conform to the Darwinian paradigm in unexpected detail and is thus may be considered a theory within the framework of Universal Darwinism. With the inclusion of Quantum Darwinism within Universal Darwinism and the explanatory power of Darwinian processes extended beyond biology and the social sciences to include the creation and evolution of scientific subject matter within particle physics, atomic physics and chemistry, it is suggested that Universal Darwinism may be considered a candidate 'Theory of Everything' as anticipated by David Deutsch.
Abstract Adaptive mutation, the phenomenon where organisms appear to increase beneficial mutation rates in response to environmental stress, has challenged the traditional understanding of random mutations in evolutionary biology. Here, we present a novel computational model, the Entangled Evolution Model, which integrates quantum game theory and quantum walks to provide a new approach to understanding mutation dynamics. By applying the Clauser-Horne-Shimony-Holt (CHSH) quantum game within a modified Lotka-Volterra framework, we simulate how quantum entanglement can accelerate the rate of adaptive mutations in Escherichia coli populations. Our simulations reveal that entangled bacterial populations achieve successful adaptive mutations with an 85% probability, significantly surpassing the classical theoretical maximum. These results introduce a new perspective on computational approaches to evolutionary adaptation, offering an efficient algorithmic framework to explore the role of quantum effects in biological systems.
I propose to treat the biological evolution of genoms by means of quantum mechanical tools. We start with the concept of meta- gene, which specifies the "selfish gene" of R.Dawkins. Meta- gene encodes the abstract living unity, which can live relatively independently of the others, and can contain a few real creatures. Each population of living creatures we treat as the wave function on meta- genes, which module squared is the total number of creatures with the given meta-gene, and the phase is the sum of "aspirations" to change the classical states of meta- genes. Each individual life thus becomes one of possible outcomes of the virtual quantum measurement of this function. The evolution of genomes is described by the unitary operator in the space of psi-functions or by Kossovsky-Lindblad equation in the case of open biosystems. This operator contains all the information about specific conditions under which individuals are, and how "aspirations" of their meta- genes may be implemented at the biochemical level. We show the example of quantum description of the population with two parts of meta-gene: "wolves" and "deer", which can be simultaneously in the same abstract living unity. "Selfish gene" reconciled with the notion of individuality of alive beings that gives possibility to consider evolutionary scenarios and their possible physical causes from the single position.