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Scheme for Entering Binary Data Into a Quantum Computer

Colin P. Williams

Published Mar 1, 2005• 0 citations
OpenAlex

Abstract

A quantum algorithm provides for the encoding of an exponentially large number of classical data bits by use of a smaller (polynomially large) number of quantum bits (qubits). The development of this algorithm was prompted by the need, heretofore not satisfied, for a means of entering real-world binary data into a quantum computer. The data format provided by this algorithm is suitable for subsequent ultrafast quantum processing of the entered data. Potential applications lie in disciplines (e.g., genomics) in which one needs to search for matches between parts of very long sequences of data. For example, the algorithm could be used to encode the N-bit-long human genome in only log2N qubits. The resulting log2N-qubit state could then be used for subsequent quantum data processing - for example, to perform rapid comparisons of sequences.

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All the data stored and processed by our computers is encoded as sequences of zeros and ones, called bits. Quantum computers offer an alternative to this traditional way of encoding and manipulating information. The information in a collection of qubits can be a combination, also called a superposition, over many possible sequences of zeros and ones. Where classical computation consists of flipping zeros and ones, quantum computation consists of manipulating high-dimensional vectors called quantum states. Researchers have found ways to use this to engineer quantum algorithms that solve some tasks much faster than any classical computer would. These are called quantum advantages, and are proven for specific tasks, such as breaking some encryption schemes and solving certain large linear systems. The goal of this thesis was to find new tasks for which quantum computers provably have an advantage over classical computers. In this thesis, I present two such advantages and associated results. The first one revolves around a physically relevant learning task. In other words, I explore how quantum computers can be used to help solve specialized machine learning tasks. The second one addresses the simulation of classical systems. One of the first high-potential and natural uses of quantum computers was the simulation of quantum systems. A lot of real-world problems, however, are ruled by classical physics. It turns out that quantum computers are well suited for the simulation of some exponentially large classical systems. In this thesis, I add a new problem to this list.

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inquantio

• Development of the quantum algorithm 'QuBio.py' for searching and analyzing genetic information. • Successful detection of a 50-nucleotide target sequence within a 3,022-nucleotide database using a 127-qubit simulator on the IBM quantum platform. • Securing flexibility that allows up to a 30% mismatch rate... Heralding a new horizon for synthetic biology and new drug development. [Quantum Biology Society] A "quantum computing"-based gene search algorithm has emerged, capable of analyzing exponentially increasing biological data at ultra-high speeds, surpassing the limitations of conventional computers. A study titled "GENETIC ENGINEERING THROUGH QUANTUM CIRCUITS: CONSTRUCTION OF CODES AND ANALYSIS OF GENETIC ELEMENTS BIOBLOQU" was recently published on bioRxiv, a preprint repository for biological sciences. The research team, including Patrícia Verdugo Pascoal, presented an innovative model that explores and manipulates genetic information utilizing quantum mechanics. ■ Translating the Four DNA Bases into Quantum Language... The Evolution of 'Grover's Algorithm' Modern biology generates approximately 1 Gb of sequencing data per hour, but analyzing this data using classical computing methods faces significant limitations. Existing database search methods require computation time proportional to the data size (O(N)), but the quantum-based 'Grover's algorithm' applied by the researchers can significantly reduce this to the O(√N}) level. In particular, a key feature of this study is that it adapted the algorithm to process the four nucleotides (A, T, G, C) that make up DNA, rather than simple binary symbols, thereby enabling it to operate efficiently on more complex datasets. ■ Detecting the Cas9 Target Sequence with 127 Qubits... Creation of Synthetic Genome (BioBloQu) Based on the 127-qubit simulator of the IBM cloud platform, the research team developed its own quantum algorithm code named 'QuBio.py'. Through this algorithm, they succeeded in finding a specific 50-nucleotide target DNA sequence within a genetic database consisting of up to 3,022 nucleotides. A conserved functional domain of the Cas9-like nucleotide sequence found in Brazilian biomes was used as the target sequence. Notably, this quantum algorithm permits a mismatch rate of up to 30% during the sequence comparison process. This enables flexible and rapid analysis in situations where sequence variations are expected, such as homologous gene analysis or evolutionary studies. Furthermore, based on these search results, the team succeeded in constructing a synthetic structure called a 'Quantum Biological Block (BioBloQu)' inside minimal cells (JCVI-syn3.0). The researchers stated that this algorithm "constitutes a unique starting point for developing a more sophisticated model for the manipulation of data". They also predicted that "the integration of quantum computing with artificial intelligence represents an attractive avenue... By optimizing genetic algorithms and facilitating real-time data analyses, quantum computing can revolutionize trait discovery processes in agriculture and biotechnology". This achievement is evaluated as an important example demonstrating how quantum computing can contribute to next-generation synthetic biology technologies that analyze large-scale genetic big data and design genomes from the bottom up.

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Abstract Quantum computers are designed to outperform standard computers by running quantum algorithms. Areas in which quantum algorithms can be applied include cryptography, search and optimisation, simulation of quantum systems and solving large systems of linear equations. Here we briefly survey some known quantum algorithms, with an emphasis on a broad overview of their applications rather than their technical details. We include a discussion of recent developments and near-term applications of quantum algorithms.

arXiv:1511.04206•npj Quantum Information•Jan 12, 2016•1,071 citations
A quantum algorithm provides for the encoding of an exponentially large number of classical data bits by use of a smaller (polynomially large) number of quantum bits (qubits). The development of this algorithm was prompted by the need, heretofore not satisfied, for a means of entering real-world binary data into a quantum computer. The data format provided by this algorithm is suitable for subsequent ultrafast quantum processing of the entered data. Potential applications lie in disciplines (e.g., genomics) in which one needs to search for matches between parts of very long sequences of data. For example, the algorithm could be used to encode the N-bit-long human genome in only log2N qubits. The resulting log2N-qubit state could then be used for subsequent quantum data processing - for example, to perform rapid comparisons of sequences.
In computer terminology, encoding is the process of placing a specific code or a sequence of characters (in the form of certain symbols, punctuation, numbers, or letters) into a specific format for storage or efficient transmission. Today, quantum computers have been pitched to deliver the computing power necessary to solve computationally complex problems, that are currently thought to be difficult for classical computers. With the arrival of quantum machine learning algorithms, it has become important to explore unique methods of encoding and compressing data with qubits. In this paper, we will explore the possibility of linear bit-by-bit data compression in the state vector of a multi-qubit system. We will achieve this, by looking at a brief introduction to the topic, a possible way by which we could encode bits in a state vector and whether this system of encoding can be applied to a real time system. We will also elaborate on a possible application through a proposed protocol for secure communication, and suggest a further line of discussion on this topic.
Encoding classical data into quantum systems is a foundational step in the execution of nearly all quantum algorithms, and a critical bottleneck in realizing practical quantum advantage. This review provides a comprehensive account of the concepts, algorithms, and practical considerations associated with quantum data encoding. We trace the development from its early conceptual foundations to recent advances, considering commonly used access models, such as quantum state preparation, unitary synthesis, QRAM and block encoding. We survey the circuit size, depth, space-time tradeoffs, as well as non-Clifford resources required for fault-tolerant implementation. We also discuss the roles of different access models in quantum algorithms. Special attention is given to structured data, such as sparse data, Boolean functions and data represented by tensor networks. This review bridges theory and applications, serving both as a pedagogical guide for newcomers and as a reference for active researchers. We also highlight the pivotal role of quantum data encoding in quantum computing and provide insights into future directions that will enable quantum advantage.
All the data stored and processed by our computers is encoded as sequences of zeros and ones, called bits. Quantum computers offer an alternative to this traditional way of encoding and manipulating information. The information in a collection of qubits can be a combination, also called a superposition, over many possible sequences of zeros and ones. Where classical computation consists of flipping zeros and ones, quantum computation consists of manipulating high-dimensional vectors called quantum states. Researchers have found ways to use this to engineer quantum algorithms that solve some tasks much faster than any classical computer would. These are called quantum advantages, and are proven for specific tasks, such as breaking some encryption schemes and solving certain large linear systems. The goal of this thesis was to find new tasks for which quantum computers provably have an advantage over classical computers. In this thesis, I present two such advantages and associated results. The first one revolves around a physically relevant learning task. In other words, I explore how quantum computers can be used to help solve specialized machine learning tasks. The second one addresses the simulation of classical systems. One of the first high-potential and natural uses of quantum computers was the simulation of quantum systems. A lot of real-world problems, however, are ruled by classical physics. It turns out that quantum computers are well suited for the simulation of some exponentially large classical systems. In this thesis, I add a new problem to this list.
Quantum machine learning (QML), an emerging discipline with applications in various domains, has the potential to dramatically improve deep learning while reducing model complexity. Quantum computers are well suited for machine learning (ML) tasks, especially because ML models are rapidly growing and require large amounts of data to learn. For example, classical computers that train large language and foundation models typically require supercomputers. If a need exists to double the number of model parameters, one will have to double the size of the supercomputer needed to train it. A quantum computer's parameter or state space grows exponentially with the number of qubits. This means doubling the number of model parameters only requires adding one quantum bit. Another advantage is that quantum computers can use entanglement and interference to potentially learn patterns with less data. Currently, no existing solutions compares the performance of classical and quantum machine learning algorithms for a workflow comprised of multiple ML tasks. This poster presents a QML workspace to explore and verify these QML algorithms with different available quantum frameworks such as Qisklt, CUDA Quantum, and PennyLane in a consistent, reproducible, and theoretically sound way and provide a comparison with similar classical machine learning algorithms.
• Development of the quantum algorithm 'QuBio.py' for searching and analyzing genetic information. • Successful detection of a 50-nucleotide target sequence within a 3,022-nucleotide database using a 127-qubit simulator on the IBM quantum platform. • Securing flexibility that allows up to a 30% mismatch rate... Heralding a new horizon for synthetic biology and new drug development. [Quantum Biology Society] A "quantum computing"-based gene search algorithm has emerged, capable of analyzing exponentially increasing biological data at ultra-high speeds, surpassing the limitations of conventional computers. A study titled "GENETIC ENGINEERING THROUGH QUANTUM CIRCUITS: CONSTRUCTION OF CODES AND ANALYSIS OF GENETIC ELEMENTS BIOBLOQU" was recently published on bioRxiv, a preprint repository for biological sciences. The research team, including Patrícia Verdugo Pascoal, presented an innovative model that explores and manipulates genetic information utilizing quantum mechanics. ■ Translating the Four DNA Bases into Quantum Language... The Evolution of 'Grover's Algorithm' Modern biology generates approximately 1 Gb of sequencing data per hour, but analyzing this data using classical computing methods faces significant limitations. Existing database search methods require computation time proportional to the data size (O(N)), but the quantum-based 'Grover's algorithm' applied by the researchers can significantly reduce this to the O(√N}) level. In particular, a key feature of this study is that it adapted the algorithm to process the four nucleotides (A, T, G, C) that make up DNA, rather than simple binary symbols, thereby enabling it to operate efficiently on more complex datasets. ■ Detecting the Cas9 Target Sequence with 127 Qubits... Creation of Synthetic Genome (BioBloQu) Based on the 127-qubit simulator of the IBM cloud platform, the research team developed its own quantum algorithm code named 'QuBio.py'. Through this algorithm, they succeeded in finding a specific 50-nucleotide target DNA sequence within a genetic database consisting of up to 3,022 nucleotides. A conserved functional domain of the Cas9-like nucleotide sequence found in Brazilian biomes was used as the target sequence. Notably, this quantum algorithm permits a mismatch rate of up to 30% during the sequence comparison process. This enables flexible and rapid analysis in situations where sequence variations are expected, such as homologous gene analysis or evolutionary studies. Furthermore, based on these search results, the team succeeded in constructing a synthetic structure called a 'Quantum Biological Block (BioBloQu)' inside minimal cells (JCVI-syn3.0). The researchers stated that this algorithm "constitutes a unique starting point for developing a more sophisticated model for the manipulation of data". They also predicted that "the integration of quantum computing with artificial intelligence represents an attractive avenue... By optimizing genetic algorithms and facilitating real-time data analyses, quantum computing can revolutionize trait discovery processes in agriculture and biotechnology". This achievement is evaluated as an important example demonstrating how quantum computing can contribute to next-generation synthetic biology technologies that analyze large-scale genetic big data and design genomes from the bottom up.
Abstract Quantum computers are designed to outperform standard computers by running quantum algorithms. Areas in which quantum algorithms can be applied include cryptography, search and optimisation, simulation of quantum systems and solving large systems of linear equations. Here we briefly survey some known quantum algorithms, with an emphasis on a broad overview of their applications rather than their technical details. We include a discussion of recent developments and near-term applications of quantum algorithms.