Quantum federated learning (QFL) on NISQ hardware is highly sensitive to backend heterogeneity: some clients contribute informative updates, while others contribute noise-dominated drift that uniform averaging cannot distinguish. We propose Q-RAIL (Quantum Reliability-Aware Federated Inference and Learning), a circuit- and calibration-aware aggregation method for hardware-heterogeneous QFL. Q-RAIL computes a client-specific effective noise budget from backend calibration metadata together with transpiled circuit statistics. This budget is converted into stabilized aggregation weights using temperature scaling, uniform mixing, and a minimum-weight floor. Q-RAIL was evaluated across multiple experimental settings, including an ablation study, and benchmarked against state-of-the-art methods on three datasets: MNIST, Fashion-MNIST, and OrganAMNIST. On the primary MNIST benchmark under strong hardware skew, Q-RAIL improves final test accuracy from FedAvg's 0.777 to 0.877, a +10.0-point gain corresponding to about 44.8% relative error reduction, while also exceeding the strongest wpQFL baseline (0.833). At the same time, test loss drops from 0.722 to 0.585, and test AUC rises from 0.920 to 0.973. Under non-IID MNIST, Q-RAIL reaches 0.813 vs 0.722 for FedAvg. It also outperforms FedAvg in 12/12 ansatz/CX-fold stress configurations and remains stronger at 4, 10, and 15 qubit setups. Overall, the results support calibration-driven, circuit-aware aggregation as a practical path toward robust QFL on heterogeneous quantum hardware.
The convergence of quantum computing and distributed edge intelligence presents new possibilities for advancing federated learning in NISQ-era settings. Conventional federated learning, however, becomes increasingly vulnerable to decoherence, communication noise, and heterogeneous client data when extended to quantum-enabled systems. This work proposes an Entanglement-Aware Federated Quantum Learning (EAFQL) framework that couples local variational quantum circuit (VQC) training with a fidelity-weighted aggregation rule at the server. The use of entanglement fidelity as a weighting factor allows the aggregation process to compensate for noise-induced degradation in the client-server links. A corresponding theoretical model is developed, and the framework is implemented in a hybrid simulation environment using Qiskit and PennyLane. Experimental results show that EAFQL attains accuracy comparable to classical FedAvg while offering improved stability. The method remains effective under non-IID data distributions, synthetic depolarizing and amplitude-damping noise, and varying entanglement-distribution topologies. These findings indicate that fidelity-aware aggregation can enhance the reliability of federated learning in emerging quantum-classical edge networks.
AI-driven medical diagnostics increasingly requires collaborative model training across institutions, yet centralizing patient data conflicts with privacy regulations. Federated Learning enables distributed training without raw data sharing, but remains vulnerable to gradient inversion and model leakage attacks. Furthermore, harvest-now-decrypt-later attacks render computationally secure protocols insufficient for protecting long-lived medical records. Quantum communication offers information-theoretic security immune to such threats, making Quantum Federated Learning (QFL) a compelling framework for healthcare. However, practical deployment is constrained by communication overhead and quantum channel noise. We present a systematic quantitative study of communication, convergence, and noise trade-offs in QFL, introducing two complementary strategies to reduce quantum transmissions: (1) structured parameter reduction via light-cone feature selection in parameterized quantum circuits, and (2) a Hybrid QFL architecture that dynamically switches between centralized and decentralized aggregation. We show that Hybrid QFL reduces total quantum transmissions from
3TNMP, the cost of pure Centralized QFL, to
{3t+2(T−t)}NMP over
T rounds while preserving near-centralized convergence. We further demonstrate that decentralized aggregation is more noise-resilient under depolarizing noise, and evaluate Steane code-based quantum error correction in high-noise regimes. Our results provide an integrated design framework for communication-efficient, noise-aware QFL, clarifying practical trade-offs for scalable quantum-secure distributed learning in healthcare.