Abstract The Internet of Medical Things (IoMT) is revolutionizing the healthcare industry through connected medical devices and real-time data exchange. However, the sensitive nature of this data requires a security infrastructure capable of resisting both current and future threats, including those posed by quantum computing. This paper presents a unified framework that combines Software-Defined Networking (SDN), Blockchain, and Quantum Cryptography to secure IoMT systems. The SDN architecture is enhanced with a Quantum Key Distribution (QKD) plane for quantum-safe session key generation and a Blockchain plane for decentralized identity verification. To improve efficiency, we introduce a self-mutable blockchain, blocks are automatically deleted after expiration to reduce storage and maintain scalability, while remaining tamper-resistant to attackers. The system utilizes Kyber, a lattice-based quantum-resistant algorithm, to mitigate future quantum threats. The proposed protocol was evaluated through mainnet simulation, BAN logic, and AVISPA formal verification, confirming strong security against classical and quantum attack vectors. This framework delivers a scalable, efficient, and future-ready solution for secure IoMT networks.
Abstract The Internet of Medical Things (IoMT) is revolutionizing the healthcare industry through connected medical devices and real-time data exchange. However, the sensitive nature of this data requires a security infrastructure capable of resisting both current and future threats, including those posed by quantum computing. This paper presents a unified framework that combines Software-Defined Networking (SDN), Blockchain, and Quantum Cryptography to secure IoMT systems. The SDN architecture is enhanced with a Quantum Key Distribution (QKD) plane for quantum-safe session key generation and a Blockchain plane for decentralized identity verification. To improve efficiency, we introduce a self-mutable blockchain, blocks are automatically deleted after expiration to reduce storage and maintain scalability, while remaining tamper-resistant to attackers. The system utilizes Kyber, a lattice-based quantum-resistant algorithm, to mitigate future quantum threats. The proposed protocol was evaluated through mainnet simulation, BAN logic, and AVISPA formal verification, confirming strong security against classical and quantum attack vectors. This framework delivers a scalable, efficient, and future-ready solution for secure IoMT networks.
The convergence of 6G communication technologies and the Internet of Medical Things (IoMT) has revolutionized modern healthcare by enabling real-time monitoring, intelligent diagnosis, and remote patient management. However, the proliferation of interconnected medical devices also exposes the ecosystem to severe security challenges, including identity forgery, data tampering, and emerging quantum-based attacks. To address these challenges, this paper proposes a blockchain-assisted quantum signature framework for securing data exchange in 6G - enabled IoMT environments. The proposed framework leverages quantum digital signatures (QDS) based on entangled photon states to ensure message authenticity and non-repudiation, while blockchain technology provides decentralized trust management and immutable transaction logging. A Medical Authorization Center (MAC) coordinates identity registration, signature verification, and consensus-based access control among IoMT entities. Furthermore, smart contracts are utilized to automate trust evaluation and audit trails, thereby mitigating insider and replay attacks. Performance analysis using Qiskit simulations and IBM’s quantum backends demonstrates an average signature fidelity of 91% and a communication efficiency of 75.61%, validating the framework’s robustness for resource-constrained medical devices. By fusing quantum communication primitives with blockchain-enabled transparency, this work presents a scalable and tamper-resistant security solution for next-generation healthcare networks. The convergence of 6G communication technologies and the Internet of Medical Things (IoMT) has revolutionized modern healthcare by enabling real-time monitoring, intelligent diagnosis, and remote patient management. However, the proliferation of interconnected medical devices also exposes the ecosystem to severe security challenges, including identity forgery, data tampering, and emerging quantum-based attacks. To address these challenges, this paper proposes a blockchain-assisted quantum signature framework for securing data exchange in 6G-enabled IoMT environments. The proposed framework leverages quantum digital signatures (QDS) based on entangled photon states to ensure message authenticity and non-repudiation, while blockchain technology provides decentralized trust management and immutable transaction logging. A Medical Authorization Center (MAC) coordinates identity registration, signature verification, and consensus-based access control among IoMT entities. Furthermore, smart contracts are utilized to automate trust evaluation and audit trails, thereby mitigating insider and replay attacks. Performance analysis using Qiskit simulations and IBM’s quantum backends demonstrates an average signature fidelity of 91% and a communication efficiency of 75.61%, validating the framework’s robustness for resource-constrained medical devices. By fusing quantum communication primitives with blockchain-enabled transparency, this work presents a scalable and tamper-resistant security solution for next-generation healthcare networks.
The rapid expansion of Internet of Medical Things (IoMT) networks has enabled continuous data collection from diverse medical sensors and devices, supporting real-time monitoring, diagnostics, and decision-making. However, the resource limitations of IoT nodes and the open nature of communication channels make healthcare data vulnerable to security and privacy breaches. To address these challenges, this paper presents a blockchain-assisted, privacy-preserving signature scheme leveraging Quantum Key Distribution (QKD) to ensure secure and trustworthy data sharing in Healthcare Internet of Things (H-IoT) environments. The proposed scheme integrates a quantum-designated verifier signature mechanism with a private blockchain infrastructure, where peer nodes validate and store healthcare data securely. Formal (software-based) and informal security analyses demonstrate the scheme's resistance to forgery, replay, and quantum attacks. Simulation experiments conducted in Python show that the proposed protocol achieves strong cryptographic performance, with a computational cost of 42.1ms and a communication overhead of 834 bits. Additionally, a blockchain-based prototype implementation quantifies the time required to append various numbers of blocks and process multiple healthcare transactions, confirming the scalability and practicality of the proposed solution. The results affirm that the scheme offers a reliable, efficient, and quantum-resilient framework for securing sensitive medical data across distributed IoMT healthcare systems.
The convergence of blockchain technology and the Internet of Medical Things (IoMT) significantly enhances data security and interoperability in healthcare systems. However, emerging quantum computing capabilities pose critical threats to conventional cryptographic algorithms underpinning blockchain security. Moreover, as IoMT devices manage sensitive patient data and perform essential healthcare functions, ensuring robust protection against both classical and quantum attacks has become increasingly urgent. To mitigate these risks, this paper introduces a Post-Quantum Cryptography Integration Framework (PQCIF), designed to protect blockchain-enabled IoMT (BIoMT) systems and infrastructures against classical and quantum attacks. PQ-CIF is a hybrid framework leveraging NIST-standardized post-quantum cryptographic (PQC) algorithms combined with conventional public-private key pair cryptography schemes, strategically integrating them within BIoMT architectures for robust long-term security. We provide comprehensive evaluation metrics and present a detailed case study demonstrating the efficacy and minimal overhead of our proposed framework in a simulated healthcare blockchain network.
The rapid adoption of Internet of Medical Things (IoMT) devices enables real-time patient monitoring and remote diagnostics and has revolutionized healthcare delivery. Traditional cryptographic schemes like RSA and ECC, which rely on meaningful mathematical challenges, are under great threat from quantum computing, threatening sensitive medical data confidentiality and integrity. This paper proposes a quantum-resistant healthcare security framework based on lattice-based cryptographic primitives such as Learning With Errors (LWE), Ring-LWE (RLWE), and Short Integer Solution (SIS). To this end, we design a five-phase IoMT-friendly framework—Initialization, Registration, Authentication, Data Exchange, and Treatment—where each phase is backed up by lightweight cryptography primitives that can be easily implemented on the low-resource IoMT devices. Relative to the state-of-the-art lattice- and hash-based constructions, our framework involves 50-75% smaller ciphertext sizes, up to a 50% reduction of the communication overhead, and nearly 60% less in computational cost. Furthermore, the solution relies on zero-knowledge proofs, homomorphic encryption as well and attribute-based access control to guarantee strong security and privacy. Using the AVISPA tool, the framework is formally verified, showing its resistance against classical and quantum adversaries. Focusing on tangible healthcare threats, including data tampering and unlicensed access to patient diagnostics, this research paves the way for scalable, efficient, and quantum-resistant medical data protection. Our results pave the way for future investigations into secure post-quantum healthcare and IoT applications.
The Internet of Medical Things (IoMT) is a compelling networking paradigm integrating wireless communications sensors, connected devices, and embedded computing technologies. The IoMT involves the collection of real-time health data using sophisticated medical sensors. In recent years, the IoMT has become increasingly significant within the broader context of the Internet of Things (IoT). It provides accessibility for health monitoring and poses security obstacles to safeguarding the confidentiality and privacy of patient data. Therefore, this article presents a blockchain-integrated quantum authentication scheme in sensor-assisted IoMT networks. The proposed concept utilizes blockchain technology to achieve efficient patient authentication without the need for third-party entities. In addition, a secure quantum authentication scheme is designed not to require patients to authenticate themselves when communicating with multiple doctors simultaneously. This protocol explicitly addresses how clinicians can misuse their professional roles toward patients in IoMT networks. An evaluation analysis assesses the proposed technique’s efficacy compared to existing authentication schemes. The performance analyses demonstrate that the proposed protocol is resilient against various security attacks. Also, the practical usability of the quantum authentication scheme proved its importance as a significant improvement in communication security for IoMT networks.
The rapid digitalisation of healthcare has accelerated the adoption of telemedicine, Electronic Health Records (EHRs), and the Internet of Medical Things (IoMT), transforming healthcare delivery into a highly interconnected and patient-centric ecosystem. In response to growing concerns about data security, privacy, and interoperability, blockchain technology has emerged as a promising solution for its decentralization, immutability, auditability, and secure access control. However, many existing blockchain infrastructures rely on classical cryptographic primitives, including RSA- or elliptic-curve-based public-key mechanisms and cryptographic hash functions such as SHA-256, whose relevant security properties may be affected by sufficiently powerful quantum attacks. This review investigates the convergence of blockchain and quantum technologies to address emerging security threats in e-health systems. A structured literature review was conducted in accordance with the PRISMA 2020 guidelines using the IEEE Xplore, PubMed, ACM Digital Library, Google Scholar, and Crossref databases, covering studies published between January 2018 and June 2025. Following a systematic screening and eligibility-verification process, 57 relevant studies were selected and analyzed. The review evaluates quantum-resilient security mechanisms, including Quantum Key Distribution (QKD), Quantum Random Number Generation (QRNG), and NIST-standardized Post-Quantum Cryptography (PQC) algorithms specified in FIPS 203, FIPS 204, and FIPS 205. Based on the identified research gaps in the state of the art, this study also proposes a novel four-layer Quantum-Blockchain Security Architecture (QBSA) designed for secure healthcare environments. The analysis further reveals significant challenges associated with lightweight PQC deployment for IoMT devices, interoperability standardization, quantum hardware limitations, and regulatory compliance in cross-institutional healthcare systems. The findings highlight the necessity of integrating quantum-resilient cryptographic frameworks with blockchain infrastructures to support the development of secure, scalable, and patient-centric next-generation e-health ecosystems.