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Quantum Frontiers Journal

Hybrid Quantum-Classical Algorithms for Complex Computational Tasks

Helena Popescu

Published Mar 28, 2024• 0 citations
OpenAlex

Abstract

Hybrid quantum-classical algorithms represent the dominant computational paradigm for near-term quantum advantage: classical co-processors handle data pre-processing, parameter optimisation, and post-processing, while quantum processors execute short-depth circuits that exploit superposition and entanglement for tasks classically hard to simulate. Despite growing interest, a systematic framework for designing, benchmarking, and selecting hybrid architectures across diverse computational task categories has been absent. This paper proposes the Hybrid Quantum-Classical Algorithm Design (HQCAD) framework, covering four hybrid paradigms: Variational Quantum-Classical Loops (VQCL) for optimisation and ground-state estimation; Quantum-Enhanced Machine Learning (QEML) combining quantum feature maps with classical classifiers; Quantum-Classical Divide-and-Conquer (QCDC) for graph and combinatorial problems; and Quantum-Accelerated Monte Carlo (QAMC) for sampling-based inference. HQCAD is benchmarked on six tasks -- molecular ground-state energy, binary classification, graph partitioning, financial Monte Carlo, protein fold scoring, and logistics routing -- on IBM Quantum Eagle (127-qubit) and IonQ Aria (25-qubit). VQCL achieves chemical accuracy (error < 1.6 mHa) for H2O ground-state energy. QEML achieves test AUC = 0.924 vs. classical SVM 0.884 on a quantum-advantage dataset. QAMC delivers 8.4x variance reduction for financial option pricing vs. classical Monte Carlo at equal shot budget. HQCAD provides a task-adaptive hybrid algorithm selection methodology validated across six computational domains.

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Hybrid Quantum-AI Architectures for Intelligent Decision Systems

Andreas Novak, Marta Moreau, Isabella Klein

Intelligent decision systems -- AI architectures that synthesise multi-source information to produce actionable decisions in complex environments -- increasingly encounter problem structures where quantum computational resources could provide meaningful advantage: high-dimensional state spaces, combinatorial action selection, uncertainty quantification under exponential hypothesis spaces, and real-time optimisation under resource constraints. This paper proposes the Hybrid Quantum-AI Decision System (HQADS) framework, integrating quantum computational modules into classical AI decision pipelines across four architectural patterns: quantum-enhanced reinforcement learning (QERL) using variational quantum circuits as policy networks in deep RL; quantum Bayesian inference (QBI) leveraging quantum amplitude estimation for posterior probability computation; quantum-accelerated planning (QAP) using Grover-enhanced tree search for sequential decision problems; and quantum ensemble decision fusion (QEDF) combining quantum superposition for multi-model ensemble aggregation. HQADS is evaluated on four decision system benchmarks: autonomous logistics routing (QERL), medical differential diagnosis (QBI), game-tree search (QAP), and multi-sensor fusion classification (QEDF) on IBM Quantum Eagle and IonQ Aria. QERL achieves 18.4% higher reward than classical DQN on the quantum-structured logistics environment. QBI reduces posterior computation time by 6.4x vs. classical MCMC at equal accuracy. QAP achieves 4.8x speedup for depth-12 game-tree search. QEDF improves multi-sensor classification AUC by 3.8pp vs. classical ensemble. HQADS provides a systematic integration methodology for quantum modules in AI decision pipelines with validated performance across four decision domains.

Quantum Frontiers Journal•Mar 28, 2025•0 citations

Quantum Data Encoding and Variational Algorithms: A Framework for Hybrid Quantum Classical Machine Learning

Bhavna Bose, Saurav Verma

The development of quantum computers has been the stimulus that enables the realization of Quantum Machine Learning (QML), an area that integrates the calculational framework of quantum mechanics with the adaptive properties of classical machine learning. This article suggests a broad architecture that allows the connection between classical data pipelines and quantum algorithms, hybrid quantum-classical models emerge as a promising route to scalable and near-term quantum benefit. At the core of this paradigm lies the Classical-Quantum (CQ) paradigm, in which the qubit states of high-dimensional classical data are encoded using sophisticated classical encoding strategies which encode the data in terms of amplitude and angle of rotation, along with superposition mapping. These techniques allow compression of information exponentially into Hilbert space representations, which, together with reduced sample complexity, allows greater feature expressivity. We also examine variational quantum circuits, quantum gates expressed as trainable variables that run with classical optimizers to overcome decoherence, noise, and gate-depth constraints of the existing Noisy Intermediate-Scale Quantum (NISQ) devices. Experimental comparisons with a Quantum Naive Bayes classifier prove that even small quantum circuits can approximate probabilistic inference with competitive accuracy compared to classical benchmarks, and have much better robustness to noisy data distributionsThis model does not only explain the algorithmic and architectural design of QML, it also offers a roadmap to the implementation of quantum kernels, variational algorithms, and hybrid feedback loops into practice, including optimization, computer vision, and medical diagnostics. The results support the idea that hybrid architectures with strong data encoding and adaptive error protection are key to moving QML out of theory to practice.

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A Hybrid Quantum Classical Framework for Enhanced Machine Learning Performance on High Dimensional Data

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Abstract This research presents a comprehensive hybrid quantum classical machine learning framework designed to overcome the computational limitations of classical algorithms when processing high dimensional data. The study integrates parameterized quantum circuits within classical neural network architectures and demonstrates their application across optimization tasks and supervised learning problems. The framework was evaluated on combinatorial optimization benchmarks including Max Cut and Job Shop Scheduling problems alongside classification tasks using quantum annealing based feature selection. Results demonstrate that hybrid quantum classical models achieve faster convergence rates and improved accuracy in high dimensional spaces compared to classical counterparts with the quantum algorithm for Max Cut optimization outperforming complete solution searches on larger problem instances. The findings provide machine learning practitioners and quantum computing researchers with validated hybrid architectures for near term quantum device deployment.

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Hybrid Quantum-Classical Variational Algorithms for High-Dimensional Feature Selection

Dhanalakshmi V, Sreedevi K, Neethu Akkarapatty +2 more

Feature selection in high-dimensional data spaces continues to be an intrinsic challenge in machine learning algorithms, especially when the number of features regularly exceeds thousands. Traditional techniques including mutual information filters, LASSO regularization, and recursive feature elimination are limited by the computational inefficiency of brute force searching as well as poor scalability in the ultra-high-dimensional setting. In this paper, a novel technique, the Hybrid Quantum-Classical Variational Algorithm (HQCVA), that combines quantum computing and classical optimization methods in the Variational Quantum Eigensolver (VQE) approach is introduced. Specifically, the quantum part is responsible for representing the correlation structure of the input features via the Ising model. To reduce composite loss, the classical sub-system uses the Adam stochastic optimizer to update variational parameters iteratively while also balancing density between predictive accuracies, densifications and depth of quantum circuits. Using five benchmark datasets (22,000 gene data; 12,000 pixels of hyperspectral imagery; 8,500 data points of financial time series), HQCVA produces a 12-18% higher F1-score than leading, state-of-the-art classical systems while decreasing the number of selected features by 40-65%. All simulations of circuits are performed on IBM Qiskit Aer with noise added, to simulate Eagle r3 consoles. Furthermore, the results indicate that the quantum advantage scales with increasing feature dimension through this process to demonstrate that near-term quantum devices have practical applications in real-world feature selection applications.

International Journal of Artificial Intelligence and Machine Learning•May 24, 2026•0 citations

Quantum Machine Learning Approaches

Lukas Dubois

Quantum machine learning sits at the intersection of quantum computing and artificial intelligence, seeking to exploitquantum mechanical phenomena -- superposition, entanglement, and interference -- to achieve computationaladvantages for learning tasks. This study presents a systematic evaluation of five quantum ML approaches -- variationalquantum classifiers (VQC), quantum kernel methods, quantum reservoir computing, quantum Boltzmann machines, andhybrid quantum-classical neural networks -- benchmarked against classical counterparts on both simulated quantumhardware (up to 30 qubits) and real NISQ devices (IBM Quantum, 27 qubits). Evaluations spanned four task categories:binary classification on structured datasets (6 UCI benchmarks), quantum chemistry property prediction (QM9 molecularenergies), generative modelling (learning probability distributions), and optimisation (Max-Cut on random graphs). A totalof 1,920 experiments were conducted. On classical structured datasets, no quantum method outperformed the bestclassical baseline (XGBoost or SVM) at any problem size accessible to current quantum hardware (up to 30 features),with quantum kernel methods achieving parity at 0.4 +- 0.8% accuracy difference but at 100-1000x higher computationalcost. On quantum chemistry, variational quantum eigensolvers showed a genuine advantage for small molecules (H2,LiH, BeH2): achieving chemical accuracy (1 kcal/mol) with 4-12 qubits where classical methods required exponentiallymore compute for equivalent accuracy. Noise on real NISQ devices degraded all quantum ML methods by 8.4-22.6%relative to noiseless simulation, with error mitigation recovering 42-68% of the noise-induced loss. The quantumadvantage threshold -- the problem size at which quantum methods become faster than classical for equivalent accuracy-- was estimated at 50-100 logical qubits for quantum chemistry and 200+ logical qubits for general ML tasks, placingpractical quantum ML advantage beyond current NISQ capabilities but within plausible reach of fault-tolerant devices. Apractical assessment framework mapping task type, problem structure, and available quantum hardware to expectedquantum advantage is proposed.

Bio-QI Journal•Jul 23, 2023•0 citations

Design and Analysis of Quantum Algorithms for Large-Scale Optimization Problems

Laura Bianchi

Large-scale combinatorial and continuous optimisation problems remain intractable for classical algorithms as problem dimensionality scales. Quantum computing offers advantages through parallelism, amplitude amplification, and tunnelling, but practical realisation on near-term noisy intermediate-scale quantum (NISQ) devices demands careful algorithm design balancing advantage against noise resilience and circuit depth constraints. This paper presents the Quantum Optimisation Algorithm Suite (QOAS), a systematic framework across four algorithmic paradigms: Adaptive QAOA with dynamic depth scheduling; Variational Quantum Eigensolver (VQE) for QUBO problems; hybrid Quantum Annealing (QA); and Grover-enhanced Branch and Bound (GBB) for constrained integer programming. QOAS is benchmarked on five problem classes (MaxCut, TSP, Portfolio, Drug-Target, Feature Selection) across n = 12-84 qubits on IBM Quantum Eagle (127-qubit) and Falcon (27-qubit). Adaptive QAOA achieves approximation ratio 0.924 (SD = 0.018) for MaxCut at n = 48 -- outperforming standard QAOA (0.848) and Goemans-Williamson (0.878) at equivalent wall-clock time. GBB achieves 28.4x speedup over classical branch-and-bound for the n = 24 drug-target problem. QOAS provides systematic methodology for algorithm selection, circuit depth optimisation, and noise mitigation for NISQ workloads.

Quantum Frontiers Journal•Mar 28, 2024•0 citations
Hybrid quantum-classical algorithms represent the dominant computational paradigm for near-term quantum advantage: classical co-processors handle data pre-processing, parameter optimisation, and post-processing, while quantum processors execute short-depth circuits that exploit superposition and entanglement for tasks classically hard to simulate. Despite growing interest, a systematic framework for designing, benchmarking, and selecting hybrid architectures across diverse computational task categories has been absent. This paper proposes the Hybrid Quantum-Classical Algorithm Design (HQCAD) framework, covering four hybrid paradigms: Variational Quantum-Classical Loops (VQCL) for optimisation and ground-state estimation; Quantum-Enhanced Machine Learning (QEML) combining quantum feature maps with classical classifiers; Quantum-Classical Divide-and-Conquer (QCDC) for graph and combinatorial problems; and Quantum-Accelerated Monte Carlo (QAMC) for sampling-based inference. HQCAD is benchmarked on six tasks -- molecular ground-state energy, binary classification, graph partitioning, financial Monte Carlo, protein fold scoring, and logistics routing -- on IBM Quantum Eagle (127-qubit) and IonQ Aria (25-qubit). VQCL achieves chemical accuracy (error < 1.6 mHa) for H2O ground-state energy. QEML achieves test AUC = 0.924 vs. classical SVM 0.884 on a quantum-advantage dataset. QAMC delivers 8.4x variance reduction for financial option pricing vs. classical Monte Carlo at equal shot budget. HQCAD provides a task-adaptive hybrid algorithm selection methodology validated across six computational domains.
Intelligent decision systems -- AI architectures that synthesise multi-source information to produce actionable decisions in complex environments -- increasingly encounter problem structures where quantum computational resources could provide meaningful advantage: high-dimensional state spaces, combinatorial action selection, uncertainty quantification under exponential hypothesis spaces, and real-time optimisation under resource constraints. This paper proposes the Hybrid Quantum-AI Decision System (HQADS) framework, integrating quantum computational modules into classical AI decision pipelines across four architectural patterns: quantum-enhanced reinforcement learning (QERL) using variational quantum circuits as policy networks in deep RL; quantum Bayesian inference (QBI) leveraging quantum amplitude estimation for posterior probability computation; quantum-accelerated planning (QAP) using Grover-enhanced tree search for sequential decision problems; and quantum ensemble decision fusion (QEDF) combining quantum superposition for multi-model ensemble aggregation. HQADS is evaluated on four decision system benchmarks: autonomous logistics routing (QERL), medical differential diagnosis (QBI), game-tree search (QAP), and multi-sensor fusion classification (QEDF) on IBM Quantum Eagle and IonQ Aria. QERL achieves 18.4% higher reward than classical DQN on the quantum-structured logistics environment. QBI reduces posterior computation time by 6.4x vs. classical MCMC at equal accuracy. QAP achieves 4.8x speedup for depth-12 game-tree search. QEDF improves multi-sensor classification AUC by 3.8pp vs. classical ensemble. HQADS provides a systematic integration methodology for quantum modules in AI decision pipelines with validated performance across four decision domains.
The development of quantum computers has been the stimulus that enables the realization of Quantum Machine Learning (QML), an area that integrates the calculational framework of quantum mechanics with the adaptive properties of classical machine learning. This article suggests a broad architecture that allows the connection between classical data pipelines and quantum algorithms, hybrid quantum-classical models emerge as a promising route to scalable and near-term quantum benefit. At the core of this paradigm lies the Classical-Quantum (CQ) paradigm, in which the qubit states of high-dimensional classical data are encoded using sophisticated classical encoding strategies which encode the data in terms of amplitude and angle of rotation, along with superposition mapping. These techniques allow compression of information exponentially into Hilbert space representations, which, together with reduced sample complexity, allows greater feature expressivity. We also examine variational quantum circuits, quantum gates expressed as trainable variables that run with classical optimizers to overcome decoherence, noise, and gate-depth constraints of the existing Noisy Intermediate-Scale Quantum (NISQ) devices. Experimental comparisons with a Quantum Naive Bayes classifier prove that even small quantum circuits can approximate probabilistic inference with competitive accuracy compared to classical benchmarks, and have much better robustness to noisy data distributionsThis model does not only explain the algorithmic and architectural design of QML, it also offers a roadmap to the implementation of quantum kernels, variational algorithms, and hybrid feedback loops into practice, including optimization, computer vision, and medical diagnostics. The results support the idea that hybrid architectures with strong data encoding and adaptive error protection are key to moving QML out of theory to practice.
Abstract This research presents a comprehensive hybrid quantum classical machine learning framework designed to overcome the computational limitations of classical algorithms when processing high dimensional data. The study integrates parameterized quantum circuits within classical neural network architectures and demonstrates their application across optimization tasks and supervised learning problems. The framework was evaluated on combinatorial optimization benchmarks including Max Cut and Job Shop Scheduling problems alongside classification tasks using quantum annealing based feature selection. Results demonstrate that hybrid quantum classical models achieve faster convergence rates and improved accuracy in high dimensional spaces compared to classical counterparts with the quantum algorithm for Max Cut optimization outperforming complete solution searches on larger problem instances. The findings provide machine learning practitioners and quantum computing researchers with validated hybrid architectures for near term quantum device deployment.
Feature selection in high-dimensional data spaces continues to be an intrinsic challenge in machine learning algorithms, especially when the number of features regularly exceeds thousands. Traditional techniques including mutual information filters, LASSO regularization, and recursive feature elimination are limited by the computational inefficiency of brute force searching as well as poor scalability in the ultra-high-dimensional setting. In this paper, a novel technique, the Hybrid Quantum-Classical Variational Algorithm (HQCVA), that combines quantum computing and classical optimization methods in the Variational Quantum Eigensolver (VQE) approach is introduced. Specifically, the quantum part is responsible for representing the correlation structure of the input features via the Ising model. To reduce composite loss, the classical sub-system uses the Adam stochastic optimizer to update variational parameters iteratively while also balancing density between predictive accuracies, densifications and depth of quantum circuits. Using five benchmark datasets (22,000 gene data; 12,000 pixels of hyperspectral imagery; 8,500 data points of financial time series), HQCVA produces a 12-18% higher F1-score than leading, state-of-the-art classical systems while decreasing the number of selected features by 40-65%. All simulations of circuits are performed on IBM Qiskit Aer with noise added, to simulate Eagle r3 consoles. Furthermore, the results indicate that the quantum advantage scales with increasing feature dimension through this process to demonstrate that near-term quantum devices have practical applications in real-world feature selection applications.
Quantum machine learning sits at the intersection of quantum computing and artificial intelligence, seeking to exploitquantum mechanical phenomena -- superposition, entanglement, and interference -- to achieve computationaladvantages for learning tasks. This study presents a systematic evaluation of five quantum ML approaches -- variationalquantum classifiers (VQC), quantum kernel methods, quantum reservoir computing, quantum Boltzmann machines, andhybrid quantum-classical neural networks -- benchmarked against classical counterparts on both simulated quantumhardware (up to 30 qubits) and real NISQ devices (IBM Quantum, 27 qubits). Evaluations spanned four task categories:binary classification on structured datasets (6 UCI benchmarks), quantum chemistry property prediction (QM9 molecularenergies), generative modelling (learning probability distributions), and optimisation (Max-Cut on random graphs). A totalof 1,920 experiments were conducted. On classical structured datasets, no quantum method outperformed the bestclassical baseline (XGBoost or SVM) at any problem size accessible to current quantum hardware (up to 30 features),with quantum kernel methods achieving parity at 0.4 +- 0.8% accuracy difference but at 100-1000x higher computationalcost. On quantum chemistry, variational quantum eigensolvers showed a genuine advantage for small molecules (H2,LiH, BeH2): achieving chemical accuracy (1 kcal/mol) with 4-12 qubits where classical methods required exponentiallymore compute for equivalent accuracy. Noise on real NISQ devices degraded all quantum ML methods by 8.4-22.6%relative to noiseless simulation, with error mitigation recovering 42-68% of the noise-induced loss. The quantumadvantage threshold -- the problem size at which quantum methods become faster than classical for equivalent accuracy-- was estimated at 50-100 logical qubits for quantum chemistry and 200+ logical qubits for general ML tasks, placingpractical quantum ML advantage beyond current NISQ capabilities but within plausible reach of fault-tolerant devices. Apractical assessment framework mapping task type, problem structure, and available quantum hardware to expectedquantum advantage is proposed.
Large-scale combinatorial and continuous optimisation problems remain intractable for classical algorithms as problem dimensionality scales. Quantum computing offers advantages through parallelism, amplitude amplification, and tunnelling, but practical realisation on near-term noisy intermediate-scale quantum (NISQ) devices demands careful algorithm design balancing advantage against noise resilience and circuit depth constraints. This paper presents the Quantum Optimisation Algorithm Suite (QOAS), a systematic framework across four algorithmic paradigms: Adaptive QAOA with dynamic depth scheduling; Variational Quantum Eigensolver (VQE) for QUBO problems; hybrid Quantum Annealing (QA); and Grover-enhanced Branch and Bound (GBB) for constrained integer programming. QOAS is benchmarked on five problem classes (MaxCut, TSP, Portfolio, Drug-Target, Feature Selection) across n = 12-84 qubits on IBM Quantum Eagle (127-qubit) and Falcon (27-qubit). Adaptive QAOA achieves approximation ratio 0.924 (SD = 0.018) for MaxCut at n = 48 -- outperforming standard QAOA (0.848) and Goemans-Williamson (0.878) at equivalent wall-clock time. GBB achieves 28.4x speedup over classical branch-and-bound for the n = 24 drug-target problem. QOAS provides systematic methodology for algorithm selection, circuit depth optimisation, and noise mitigation for NISQ workloads.