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International Journal of Multidisciplinary Research

Quantum Computing and Genomic Medicine: Bridging Physics, Computer Science, and Healthcare

Farah Siddiqui, Imran Haider

Published Jun 30, 2025• 0 citations
OpenAlex

Abstract

Quantum computing offers unprecedented computational power by exploiting quantum mechanical phenomena such as superposition and entanglement. Genomic medicine, the field concerned with using genomic information for diagnosis, treatment, and prevention of disease, is increasingly data intensive, with vast datasets, complex pattern recognition tasks, and computationally expensive algorithms. This article explores how quantum computing can transform genomic medicine by accelerating sequence alignment, improving variant calling, enabling efficient drug discovery, and facilitating personalized therapy design. While potential breakthroughs abound, there are challenges: quantum hardware limitations, error rates, ethical and privacy implications, and integration into existing healthcare systems. We propose a multidisciplinary framework that unites physics, computer science, and healthcare to realize these potentials. The article concludes with recommended research directions, policy implications in the Pakistani context, and a roadmap toward clinical applications.

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Quantum computing represents a paradigm shift in computational science, harnessing the principles of quantum mechanics to solve problems beyond the capacity of classical systems. Within the realm of medicine, the integration of quantum computing offers unprecedented opportunities in drug discovery, genomics, diagnostic imaging, and personalized healthcare. This article explores the multidisciplinary intersection of physics, computer science, and medical sciences, highlighting case studies from both global and Pakistani contexts. Graphical analyses illustrate the potential of quantum computing in accelerating drug discovery, optimizing diagnostic imaging, enhancing genomic analysis, and fostering public trust in quantum technologies. Despite significant promise, ethical concerns, high infrastructure costs, and the need for robust policy frameworks remain key challenges. The study concludes that quantum computing, if strategically developed, can revolutionize Pakistan’s healthcare landscape and contribute to global medical innovation.
The convergence of quantum computing and artificial intelligence (AI) presents a paradigm shift in healthcare, revolutionizing complex biological simulations, genomic data processing, and drug discovery innovations. Traditional computational methods, despite their advancements, often struggle with the sheer scale and complexity of biological data, limiting the speed and accuracy of medical breakthroughs. Quantum computing, with its ability to process vast datasets exponentially faster than classical computers, coupled with AI's predictive capabilities, offers a transformative solution for accelerating biomedical research and clinical applications. This paper explores quantum machine learning’s role in optimizing AI-driven molecular dynamics simulations for drug discovery. By leveraging quantum-enhanced algorithms, researchers can rapidly model molecular interactions, analyze drug-receptor binding affinities, and predict pharmacokinetics with unprecedented precision. Additionally, we examine quantum-assisted deep learning models for deciphering intricate biological mechanisms such as protein folding, epigenetic modifications, and metabolic pathway interactions, enabling more accurate predictions of disease progression and therapeutic targets. Furthermore, the integration of AI-quantum hybrid models in clinical diagnostics and imaging analytics is redefining personalized medicine. Quantum-enhanced deep learning facilitates high-resolution medical imaging, real-time anomaly detection, and optimized radiomic feature extraction, leading to early and more accurate disease diagnosis. In genomics, quantum computing significantly accelerates whole-genome sequencing and mutation analysis, paving the way for tailored treatment strategies based on an individual's genetic profile. Despite its promise, challenges such as quantum hardware limitations, data coherence issues, and ethical considerations must be addressed to ensure the practical implementation of quantum-AI healthcare solutions. This paper provides a comprehensive analysis of the potential, challenges, and future directions of quantum-AI synergy in transforming modern healthcare.
Quantum computing has emerged as a disruptive paradigm which can transform the information heavy areas of knowledge such as precision medicine. The expanding needs of precision medicine based on customized therapy in the light of genomics, molecular profiling, and clinical data suggest that the computation tasks can demand computational capabilities unattainable by the traditional high-performance computing. Quantum algorithms, which are founded upon the laws of superposition, entanglement and quantum parallelism, offer a scale factor of exponential on a problem in genomics, drug discovery, medical imaging and biomarker discovery. This is a review article that is a narrative synthesis of emerging trends at the interface of quantum computing and precision medicine. In particular, it discusses women topics such as patient stratification and imaging analysis with quantum machine learning (QML), protein-ligand interactions and drug discovery with quantum chemistry simulations, and quantum-classical architectures to combine complex biomedical data with clinical decision-making. Initial implementations show evidence of proof-of-concept utility in accelerating the sequencing of genomes, improving the accuracy of diagnostic imaging, and improving treatment design. With those developments, there are still major issues, such as the problem of qubit coherence, scalability of algorithms, barriers to the integration of data, and ethical concerns about transparency and fair access. To overcome these obstacles, it is necessary to physically co-evolve domain-specific quantum algorithms, powerful error-correction protocols, and cloud-friendly frameworks that can connect biomedical research to current quantum computing devices. This review offers a roadmap on how quantum computing can be leveraged to drive precision medicine to scalable, interpretable, and patient-centered healthcare solutions by outlining both early uses and future opportunities.
The convergence of quantum computing and artificial intelligence (AI) presents a paradigm shift in healthcare, revolutionizing complex biological simulations, genomic data processing, and drug discovery innovations. Traditional computational methods, despite their advancements, often struggle with the sheer scale and complexity of biological data, limiting the speed and accuracy of medical breakthroughs. Quantum computing, with its ability to process vast datasets exponentially faster than classical computers, coupled with AI\\\'s predictive capabilities, offers a transformative solution for accelerating biomedical research and clinical applications. This paper explores quantum machine learning's role in optimizing AI-driven molecular dynamics simulations for drug discovery. By leveraging quantum-enhanced algorithms, researchers can rapidly model molecular interactions, analyze drug- receptor binding affinities, and predict pharmacokinetics with unprecedented precision. Additionally, we examine quantum-assisted deep learning models for deciphering intricate biological mechanisms such as protein folding, epigenetic modifications, and metabolic pathway interactions, enabling more accurate predictions of disease progression and therapeutic targets. Furthermore, the integration of AI-quantum hybrid models in clinical diagnostics and imaging analytics is redefining personalized medicine. Quantum-enhanced deep learning facilitates high-resolution medical imaging, real-time anomaly detection, and optimized radiomic feature extraction, leading to early and more accurate disease diagnosis. In genomics, quantum computing significantly accelerates whole-genome sequencing and mutation analysis, paving the way for tailored treatment strategies based on an individual\\\'s genetic profile. Despite its promise, challenges such as quantum hardware limitations, data coherence issues, and ethical considerations must be addressed to ensure the practical implementation of quantum-AI healthcare solutions.
Quantum computing is a developing computational paradigm that uses the principles of quantum mechanics, like superposition and entanglement, to execute composite calculations beyond the abilities of conventional computers. Currently, implementation of this technology in medicine has the potential to revolutionize various domains like drug discovery, protein folding, genomics, medical imaging, and personalized healthcare. By allowing high-dimensional data processing and accurate molecular simulations, quantum computing may enhance biomedical research and thereby improving clinical decision-making. Moreover integrating quantum computing with artificial intelligence, mainly through quantum machine learning, further accelerates its capability to assess vast complex biological datasets and generate precise predictive models. Applications like disease prediction, drug response optimization, and advanced diagnostic imaging further validates its growing importance in modern healthcare. However, the implementation of quantum computing in medicine is presently limited by technical challenges, that includes decoherence, error correction, and scalability, as well as practical problems like high budgets and lack of skilled professionals. Moreover, ethical concerns play a major hurdle related to data privacy and healthcare inequality also require cautious consideration. In spite of these challenges, ongoing developments in hybrid quantum-classical systems and quantum algorithms reveal that a promising future, particularly placing quantum computing as an effective transformative force in next-generation medicine.
Quantum computing represents a promising frontier in healthcare, offering unparalleled computational power to tackle complex challenges in drug discovery and precision drugs. This paper explores the potential applications and use cases of quantum computing in healthcare. We discuss how quantum algorithms can revolutionize molecular modeling, accelerating the identification of new drug candidates and predicting their interactions with biological targets with unprecedented accuracy. Likewise, we explore how quantum computing can optimize treatment plans in precision medicine by analyzing vast datasets to tailor therapies to individual patient's genetic makeup and medical histories. Additionally, we examine the challenges and opportunities associated with integrating quantum computing into healthcare systems, including considerations around scalability, algorithm development, and data security. By harnessing the transformative capabilities of quantum computing, we envision a future where healthcare delivery is enhanced, personalized, and optimized to improve patient outcomes and advance medical science.