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Scientific Reports

Hybrid quantum-classical approach for combinatorial problems at hadron colliders

Zhongtian Dong, Taejoon Kim, Kyoungchul Kong, Myeonghun Park, Jacob L. Scott, Heechan Yi, Willie Aboumrad, Ananth Kaushik, Martin Roetteler

Published Sep 28, 2026• 0 citations
Publisher

Abstract

In recent years, quantum computing has drawn significant interest within the field of high-energy physics. We explore the potential of quantum algorithms to resolve the combinatorial problems in particle physics experiments. As a concrete example, we consider top quark pair production in the fully hadronic channel at the Large Hadron Collider. We investigate the performance of various quantum algorithms such as the Quantum Approximation Optimization Algorithm (QAOA), a feedback-based algorithm (FALQON) and a variational quantum imaginary time evolution algorithm (VarQITE). We demonstrate that the efficiency for selecting the correct pairing is greatly improved by utilizing quantum algorithms over conventional kinematic methods. Furthermore, we observe that gate-based universal quantum algorithms perform on par with machine learning techniques and either surpass or match the effectiveness of quantum annealers. Our findings reveal that quantum algorithms not only provide a substantial increase in matching efficiency but also exhibit adaptability and the potential for scalability, making them promising candidates for a variety of high-energy physics applications, as quantum hardware technology matures. Moreover, quantum algorithms eliminate the extensive training processes needed by classical machine learning methods, enabling real-time adjustments based on individual event data.

DOI
10.1038/s41598-026-69946-w

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In recent years, quantum computing has drawn significant interest within the field of high-energy physics. We explore the potential of quantum algorithms to resolve the combinatorial problems in particle physics experiments. As a concrete example, we consider top quark pair production in the fully hadronic channel at the Large Hadron Collider. We investigate the performance of various quantum algorithms such as the Quantum Approximation Optimization Algorithm (QAOA), a feedback-based algorithm (FALQON) and a variational quantum imaginary time evolution algorithm (VarQITE). We demonstrate that the efficiency for selecting the correct pairing is greatly improved by utilizing quantum algorithms over conventional kinematic methods. Furthermore, we observe that gate-based universal quantum algorithms perform on par with machine learning techniques and either surpass or match the effectiveness of quantum annealers. Our findings reveal that quantum algorithms not only provide a substantial increase in matching efficiency but also exhibit adaptability and the potential for scalability, making them promising candidates for a variety of high-energy physics applications, as quantum hardware technology matures. Moreover, quantum algorithms eliminate the extensive training processes needed by classical machine learning methods, enabling real-time adjustments based on individual event data.

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Combinatorial optimization problems play a vital role in computer science and engineering, with applications in logistics, network design, finance, and resource allocation. However, many of these problems are NP-hard, making them computationally expensive to solve using classical optimization techniques, especially for large-scale instances. In recent years, quantum computing has emerged as a promising paradigm capable of addressing these limitations by leveraging quantum mechanical principles such as superposition and entanglement. This study investigates the application of quantum computing for solving combinatorial optimization problems, with a focus on algorithm design, complexity analysis, and real-world applicability. The research primarily employs the Quantum Approximate Optimization Algorithm (QAOA) and Grover's search algorithm to solve representative problems such as Max-Cut and the Knapsack problem. The performance of these algorithms is evaluated using key metrics including accuracy, execution time, and approximation ratio, and is compared with classical optimization techniques. The results demonstrate that QAOA is capable of generating near-optimal solutions, achieving accuracy levels of up to 93% for small problem instances. However, the study also highlights the challenges associated with current quantum systems, including noise, limited qubit availability, and increased execution time. Comparative analysis reveals that while classical methods remain more efficient for small-scale problems, quantum algorithms show significant potential for scalability and handling complex optimization tasks. The findings suggest that hybrid quantum-classical approaches offer a practical solution in the current Noisy Intermediate-Scale Quantum (NISQ) era. The study concludes that although quantum computing is still evolving, it holds strong potential for transforming combinatorial optimization in the future.

•Jan 1, 2026•0 citations
In recent years, quantum computing has drawn significant interest within the field of high-energy physics. We explore the potential of quantum algorithms to resolve the combinatorial problems in particle physics experiments. As a concrete example, we consider top quark pair production in the fully hadronic channel at the Large Hadron Collider. We investigate the performance of various quantum algorithms such as the Quantum Approximation Optimization Algorithm (QAOA), a feedback-based algorithm (FALQON) and a variational quantum imaginary time evolution algorithm (VarQITE). We demonstrate that the efficiency for selecting the correct pairing is greatly improved by utilizing quantum algorithms over conventional kinematic methods. Furthermore, we observe that gate-based universal quantum algorithms perform on par with machine learning techniques and either surpass or match the effectiveness of quantum annealers. Our findings reveal that quantum algorithms not only provide a substantial increase in matching efficiency but also exhibit adaptability and the potential for scalability, making them promising candidates for a variety of high-energy physics applications, as quantum hardware technology matures. Moreover, quantum algorithms eliminate the extensive training processes needed by classical machine learning methods, enabling real-time adjustments based on individual event data.
In recent years, quantum computing has drawn significant interest within the field of high-energy physics. We explore the potential of quantum algorithms to resolve the combinatorial problems in particle physics experiments. As a concrete example, we consider top quark pair production in the fully hadronic channel at the Large Hadron Collider. We investigate the performance of various quantum algorithms such as the Quantum Approximation Optimization Algorithm (QAOA), a feedback-based algorithm (FALQON) and a variational quantum imaginary time evolution algorithm (VarQITE). We demonstrate that the efficiency for selecting the correct pairing is greatly improved by utilizing quantum algorithms over conventional kinematic methods. Furthermore, we observe that gate-based universal quantum algorithms perform on par with machine learning techniques and either surpass or match the effectiveness of quantum annealers. Our findings reveal that quantum algorithms not only provide a substantial increase in matching efficiency but also exhibit adaptability and the potential for scalability, making them promising candidates for a variety of high-energy physics applications, as quantum hardware technology matures. Moreover, quantum algorithms eliminate the extensive training processes needed by classical machine learning methods, enabling real-time adjustments based on individual event data.
Quantum algorithms offer promising advancements in solving complex optimization problems that are critical in various fields, including logistics, finance, and machine learning. Classical optimization techniques, while effective, often struggle with large-scale and high-dimensional data sets, leading to inefficiencies and long processing times.Quantum algorithms, leveraging the principles of superposition, entanglement, and quantum parallelism, provide a potential solution by exponentially speeding up certain computational tasks. This paper explores key quantum algorithms for optimization, including Grover's algorithm, the Quantum Approximate Optimization Algorithm (QAOA), and the Quantum Annealing method. We analyze their theoretical foundations, implementation challenges, and practical applications. Special attention is given to the performance comparisons between quantum and classical approaches in solving combinatorial optimization problems, such as the traveling salesman problem and portfolio optimization. We also discuss the limitations of current quantum hardware and the prospects for future improvements that could make quantum optimization algorithms more practical for real-world use.Our findings suggest that, while quantum algorithms are still in their early stages, they hold immense potential for transforming optimization in a variety of domains, offering new pathways toward more efficient problem-solving in both theoretical and applied contexts. we explore how hybrid quantum-classical approaches can enhance optimization results by combining the strengths of both paradigms. Future research directions are highlighted, focusing on improving quantum error correction, scaling quantum systems, and developing more robust quantum algorithms to tackle increasingly complex optimization problems.
Quantum computing, leveraging quantum mechanics, promises to enhance optimization processes in artificial intelligence (AI) by addressing challenges faced by classical computing in solving complex problems. This study investigates the role of quantum computing in optimizing AI tasks, focusing on algorithms such as Quantum Approximate Optimization Algorithm (QAOA) and Quantum Annealing (QA) for improved efficiency in optimization. A hybrid quantum-classical approach was used to evaluate the performance of quantum algorithms in optimization tasks, including combinatorial optimization and machine learning model tuning. QAOA and QA were applied to benchmark problems, such as Max-Cut and Traveling Salesman Problem (TSP). The study involved a comparative analysis between quantum algorithms and classical optimization techniques using performance metrics like solution quality, computational time, and scalability. Data were gathered through simulation on a quantum computing platform, and results were analyzed using statistical methods to assess improvements. The results showed that quantum computing significantly outperformed classical methods in solving large-scale optimization problems. QAOA demonstrated a 30% improvement in solution quality for Max-Cut problems, and QA showed a 25% faster convergence in TSP compared to classical algorithms. Quantum algorithms demonstrated scalability advantages as the problem size increased, with quantum methods achieving up to a 40% reduction in computational time for large instances. Furthermore, 70% of the tested cases showed significant improvements in solution accuracy, confirming the potential of quantum computing in real-world AI applications. Quantum computing, through QAOA and QA, offers substantial improvements in solving complex optimization problems in AI, presenting a transformative opportunity for the future of optimization algorithms.
Some of the most significant achievements of the modern era of particle physics, such as the discovery of the Higgs boson, have been made possible by the tremendous effort in building and operating large-scale experiments like the Large Hadron Collider or the Tevatron. In these facilities, the ultimate theory to describe matter at the most fundamental level is constantly probed and verified. These experiments often produce large amounts of data that require storing, processing, and analysis techniques that continually push the limits of traditional information processing schemes. Thus, the High-Energy Physics (HEP) field has benefited from advancements in information processing and the development of algorithms and tools for large datasets. More recently, quantum computing applications have been investigated to understand how the community can benefit from the advantages of quantum information science. Nonetheless, to unleash the full potential of quantum computing, there is a need to understand the quantum behavior and, thus, scale up current algorithms beyond what can be simulated in classical processors. In this work, we explore potential applications of quantum machine learning to data analysis tasks in HEP and how to overcome the limitations of algorithms targeted for Noisy Intermediate-Scale Quantum (NISQ) devices.
Optimization algorithms for combinatorial problems play a critical role in a wide range of applications, from logistics and scheduling to cryptography and artificial intelligence. Traditional classical methods, such as simulated annealing, genetic algorithms, and branch-and-bound techniques, have been widely employed to solve these problems, but they often face limitations in terms of computational efficiency and scalability as problem complexity grows. In recent years, quantum computing has emerged as a promising alternative, with quantum annealing offering a novel approach to solving combinatorial optimization problems. This study provides a comparative analysis of quantum annealing and classical optimization methods, highlighting their respective strengths and limitations. We explore how quantum annealing, through leveraging quantum tunnelling and superposition, has the potential to outperform classical algorithms in specific problem domains and Noisy Mean Field Annealing (NMFA) is used to comparisons of all algorithms. Benchmarking various combinatorial problems, such as the Traveling Salesman Problem (TSP), Max-Cut, Knapsack, and Quadratic Assignment Problem (QAP), this paper discusses performance metrics, computational time, and scalability. The findings suggest that while classical methods remain robust and practical for many real-world problems, quantum annealing holds significant promise, especially as quantum hardware continues to mature. However, there remain challenges in terms of noise, coherence, and problem mapping, which currently limit the full realization of quantum annealing's potential. This study offers insights into the future directions of optimization techniques and the evolving role of quantum computing in solving complex combinatorial problems.
Combinatorial optimization problems play a vital role in computer science and engineering, with applications in logistics, network design, finance, and resource allocation. However, many of these problems are NP-hard, making them computationally expensive to solve using classical optimization techniques, especially for large-scale instances. In recent years, quantum computing has emerged as a promising paradigm capable of addressing these limitations by leveraging quantum mechanical principles such as superposition and entanglement. This study investigates the application of quantum computing for solving combinatorial optimization problems, with a focus on algorithm design, complexity analysis, and real-world applicability. The research primarily employs the Quantum Approximate Optimization Algorithm (QAOA) and Grover's search algorithm to solve representative problems such as Max-Cut and the Knapsack problem. The performance of these algorithms is evaluated using key metrics including accuracy, execution time, and approximation ratio, and is compared with classical optimization techniques. The results demonstrate that QAOA is capable of generating near-optimal solutions, achieving accuracy levels of up to 93% for small problem instances. However, the study also highlights the challenges associated with current quantum systems, including noise, limited qubit availability, and increased execution time. Comparative analysis reveals that while classical methods remain more efficient for small-scale problems, quantum algorithms show significant potential for scalability and handling complex optimization tasks. The findings suggest that hybrid quantum-classical approaches offer a practical solution in the current Noisy Intermediate-Scale Quantum (NISQ) era. The study concludes that although quantum computing is still evolving, it holds strong potential for transforming combinatorial optimization in the future.