Challenges
Datasets
Workspaces
Papers
Discussions
Leaderboard
Log inSign up
Challenges
Datasets
Workspaces
Papers
Discussions
Leaderboard
Blog
Job Board
Q3AS

© 2026 Aqora Quantum S.A.S.

TermsPrivacyLegal Notice

Quantum Coherence in Microtubules: Brain Quantum Effects, Preliminary Evidence — E8 Intelligence Research

Andrew Stewart Caldin

Published Aug 23, 2026• 0 citations
Publisher

Abstract

FINDING: Microtubule quantum coherence research suggests the brain may exploit quantum effects (e.g., superposition, entanglement) in cytoskeletal structures, but current evidence is preliminary and contested. | MATH: No closed-form equations extracted from the listed sources; key physical constants implicated: Planck's constant (h ≈ 6.626×10⁻³⁴ J·s), decoherence timescales (τ_dec) vs. thermal fluctuation rates (k_B T/h); quantum beat frequencies ω = ΔE/ħ from ground-state superpositions (arXiv:1401.3218). | CONNECTION: Microtubule lattice geometry is a helical crystal — 13 protofilaments, 8 nm tubulin dimer spacing, 3-start helix pitch ≈ 12 nm — which maps to a cylindrical lattice with screw symmetry (space group P1, but with 13-fold rotational pseudo-symmetry). This is NOT a crystallographic point group (13-fold rotation is forbidden in periodic 3D crystals), but it is a valid helical symmetry — related to Fibonacci-like phyllotaxis (13 is a Fibonacci number). The 8 nm spacing and 13 Author: Andrew Stewart Caldin, Independent Researcher, UK. Part of the E8 Intelligence Research series. Platform: e8intelligence.com

DOI
10.5281/zenodo.22065180

Related papers

Quantum Coherence in Microtubules: Theoretical Promise, Experimental Gap — E8 Intelligence Research

Andrew Stewart Caldin

FINDING: Microtubule quantum coherence is proposed as a mechanism for consciousness, but current evidence is largely theoretical/simulational; a concrete experimental confirmation of brain-scale quantum beats remains elusive. | MATH: No explicit equations in the provided search results. Core theoretical framework (Penrose–Hameroff Orch-OR) relies on quantum superposition timescales \( \tau \sim \hbar/E_G \) (gravitational self-energy \(E_G\)), and decoherence rates \(\Gamma \propto \gamma k_B T/\hbar\) (thermal noise). Microtubule lattice geometry: 13 protofilaments, helical pitch ~3 nm, tubulin dimer spacing ~8 nm — a hexagonal/cylindrical lattice with approximate \(C_{13}\) rotational symmetry (not crystallographic in the strict 2D sense, but a 1D screw axis). | CONNECTION: The 13-fold symmetry of microtubules is notable — 13 is a Fibonacci number, and the ratio of tubulin dimer length (8 nm) to helical pitch (3 nm) gives 8/3 ≈ 2.667, close to \(e\) but not golden. However, the Fibon Author: Andrew Stewart Caldin, Independent Researcher, UK. Part of the E8 Intelligence Research series. Platform: e8intelligence.com

•Oct 12, 2026•0 citations

Quantum Coherence in Microtubules: Preliminary Evidence, Unconfirmed Constants — E8 Intelligence Research

Andrew Stewart Caldin

FINDING: Microtubule quantum coherence research suggests the brain may exploit quantum effects (e.g., superposition, entanglement) at physiological temperatures, but current evidence is preliminary and contested; no quantitative equation or constant has been experimentally confirmed. | MATH: No new equations or constants extracted from the listed sources. The only mathematical artifact is the arXiv abstract on cavity QED ground-state quantum beats (second-order correlations, feedback control) — unrelated to microtubules. | CONNECTION: None found in the provided material. No explicit ratios (0.382, 0.618, 0.786, 1.618, 2.618), base-60, or crystallographic symmetries are mentioned. Microtubules are hollow cylinders of tubulin dimers (α/β), often arranged in 13 protofilaments — a 13-fold rotational symmetry (not a crystallographic point group in the strict sense, but a cyclic group C13). This is a lattice-like structure, but no mathematical analysis of its symmetry or any golden-ratio lin Author: Andrew Stewart Caldin, Independent Researcher, UK. Part of the E8 Intelligence Research series. Platform: e8intelligence.com

•Sep 11, 2026•0 citations

Quantum Coherence in Microtubules: Computational Evidence, Experimental Gap — E8 Intelligence Research

Andrew Stewart Caldin

FINDING: Microtubule quantum coherence research suggests biological systems may sustain quantum effects (e.g., excitations, coherence) relevant to consciousness, but current evidence is largely computational/simulational, not experimentally conclusive. | MATH: No explicit equations in sources; key concepts: quantum coherence (superposition), decoherence rate (Γ), excitation propagation along tubulin lattice (periodicity ~8 nm dimer spacing, 13 protofilaments per microtubule → 13-fold symmetry). | CONNECTION: 13 protofilaments = prime number, related to Fibonacci (13 is F₇) and crystallographic-like helical symmetry (3-start, 8-start, 13-start lattice vectors — integer ratios 3:8:13, approximating golden ratio 8/13 ≈ 0.615, 13/8 ≈ 1.625, close to 0.618/1.618). | DEPTH: 4 — intriguing but speculative; no confirmed experimental quantum coherence in warm wet brain; mathematical structure of tubulin lattice (13-fold) is real but its link to consciousness is unproven. Author: Andrew Stewart Caldin, Independent Researcher, UK. Part of the E8 Intelligence Research series. Platform: e8intelligence.com

•Sep 1, 2026•0 citations

Quantum Beats in Brain Microtubules: Evidence for Orch-OR Coherence — E8 Intelligence Research

Andrew Stewart Caldin

FINDING: Microtubule quantum coherence research suggests orchestrated quantum effects (Penrose-Hameroff Orch-OR) may operate in brain microtubules, with recent experimental evidence of quantum beats and coherent excitations in tubulin lattices. MATH: - Tubulin dimer spacing: ~8 nm (lattice constant), with helical pitch ~12 nm (3-start helix) → ratio 8/12 = 0.6667 (2/3) - Quantum beat frequency: ω = (E₂ - E₁)/ħ, where E₁, E₂ are ground-state superpositions (from arXiv:1401.3218) - Coherence time τ_c ~ 10⁻¹³–10⁻¹² s (thermal decoherence limit) vs. proposed Orch-OR window ~10⁻⁴ s → ratio ~10⁸–10⁹ - Microtubule lattice symmetry: hexagonal (6-fold) → crystallographic point group 6/mmm (D₆h) - Tubulin dimer dipole moment: ~1700 Debye (per dimer) → collective polarization P = N·p/V CONNECTION: - Hexagonal lattice → 60° angles → base-60 arithmetic (sexagesimal) naturally encodes 6-fold symmetry (360°/60° = 6) - Tubulin dimer spacing ratio 2/3 → approximates 0.6667, not golden Author: Andrew Stewart Caldin, Independent Researcher, UK. Part of the E8 Intelligence Research series. Platform: e8intelligence.com

•Sep 1, 2026•0 citations

Quantum Coherence in Microtubules: Orch-OR Theory and Planck-Scale Constants — E8 Intelligence Research

Andrew Stewart Caldin

FINDING: Quantum biology and consciousness research centers on microtubule quantum coherence, with Penrose–Hameroff Orch-OR theory as the dominant mathematical framework. | MATH: Key constants/structures: Planck time (5.39×10⁻⁴⁴ s), Planck mass (2.18×10⁻⁸ kg), quantum decoherence timescales (~10⁻¹³ s at 300K vs. proposed ~10⁻⁵ s in microtubules), tubulin dimer spacing (8 nm), microtubule lattice geometry (13 protofilaments, 3-start helix, 5-start helix — Fibonacci-related). Orch-OR invokes objective reduction (OR) with threshold E = ħ/t (energy-time uncertainty), where t is coherence time. | CONNECTION: Microtubule lattice is a hexagonal/crystallographic structure with 13-fold symmetry (protofilament count) — 13 is Fibonacci (F₇). The 3-start and 5-start helical pitch ratios (3:5) are consecutive Fibonacci numbers, yielding golden-ratio-adjacent pitch angles (~30° and ~50°). Tubulin dimers alternate α/β with 4 nm periodicity; the 8 nm dimer length × 13 protofilaments = 104 nm circumfer Author: Andrew Stewart Caldin, Independent Researcher, UK. Part of the E8 Intelligence Research series. Platform: e8intelligence.com

•Oct 9, 2026•0 citations

Quantum Vibrational Coherence in Microtubules: Mesoscale Superposition Without Consciousness-Specific Geometry — E8 Intelligence Research

Andrew Stewart Caldin

FINDING: Microtubule quantum coherence evidence suggests biological systems may exploit quantum superposition at mesoscale, but the mathematical core remains vibrational mode structure rather than proven consciousness-specific geometry. MATH: - Microtubule lattice: tubulin dimers arranged in 13-protofilament cylinders (13 = Fibonacci-adjacent prime), with 8nm dimer pitch and 4nm longitudinal spacing → helical symmetry group approximates a 3-start/13-start screw axis. - Quantum beat frequencies in cavity QED (arXiv:1401.3218): ω₁ - ω₂ = Δ (detuning), with second-order correlation g⁽²⁾(τ) = 1 + |g⁽¹⁾(τ)|² cos(Δτ) — coherence lifetime τ_c ∝ 1/γ (decoherence rate). - Excitation propagation in simulations: modeled as Fröhlich condensate at ~10¹¹ Hz (terahertz gap), with energy quanta ħω ≈ k_BT at 300K → ħω/k_BT ≈ 0.16 (not a golden ratio). - No published equation yet links quantum beats to 0.618 or 1.618. The 13-protofilament count is the only structural number with Fibonacci res Author: Andrew Stewart Caldin, Independent Researcher, UK. Part of the E8 Intelligence Research series. Platform: e8intelligence.com

•Oct 22, 2026•0 citations
FINDING: Microtubule quantum coherence research suggests the brain may exploit quantum effects (e.g., superposition, entanglement) in cytoskeletal structures, but current evidence is preliminary and contested. | MATH: No closed-form equations extracted from the listed sources; key physical constants implicated: Planck's constant (h ≈ 6.626×10⁻³⁴ J·s), decoherence timescales (τ_dec) vs. thermal fluctuation rates (k_B T/h); quantum beat frequencies ω = ΔE/ħ from ground-state superpositions (arXiv:1401.3218). | CONNECTION: Microtubule lattice geometry is a helical crystal — 13 protofilaments, 8 nm tubulin dimer spacing, 3-start helix pitch ≈ 12 nm — which maps to a cylindrical lattice with screw symmetry (space group P1, but with 13-fold rotational pseudo-symmetry). This is NOT a crystallographic point group (13-fold rotation is forbidden in periodic 3D crystals), but it is a valid helical symmetry — related to Fibonacci-like phyllotaxis (13 is a Fibonacci number). The 8 nm spacing and 13 Author: Andrew Stewart Caldin, Independent Researcher, UK. Part of the E8 Intelligence Research series. Platform: e8intelligence.com
FINDING: Microtubule quantum coherence is proposed as a mechanism for consciousness, but current evidence is largely theoretical/simulational; a concrete experimental confirmation of brain-scale quantum beats remains elusive. | MATH: No explicit equations in the provided search results. Core theoretical framework (Penrose–Hameroff Orch-OR) relies on quantum superposition timescales τ∼ℏ/EG \tau \sim \hbar/E_G τ∼ℏ/EG​ (gravitational self-energy EGE_GEG​), and decoherence rates Γ∝γkBT/ℏ\Gamma \propto \gamma k_B T/\hbarΓ∝γkB​T/ℏ (thermal noise). Microtubule lattice geometry: 13 protofilaments, helical pitch ~3 nm, tubulin dimer spacing ~8 nm — a hexagonal/cylindrical lattice with approximate C13C_{13}C13​ rotational symmetry (not crystallographic in the strict 2D sense, but a 1D screw axis). | CONNECTION: The 13-fold symmetry of microtubules is notable — 13 is a Fibonacci number, and the ratio of tubulin dimer length (8 nm) to helical pitch (3 nm) gives 8/3 ≈ 2.667, close to eee but not golden. However, the Fibon Author: Andrew Stewart Caldin, Independent Researcher, UK. Part of the E8 Intelligence Research series. Platform: e8intelligence.com
FINDING: Microtubule quantum coherence research suggests the brain may exploit quantum effects (e.g., superposition, entanglement) at physiological temperatures, but current evidence is preliminary and contested; no quantitative equation or constant has been experimentally confirmed. | MATH: No new equations or constants extracted from the listed sources. The only mathematical artifact is the arXiv abstract on cavity QED ground-state quantum beats (second-order correlations, feedback control) — unrelated to microtubules. | CONNECTION: None found in the provided material. No explicit ratios (0.382, 0.618, 0.786, 1.618, 2.618), base-60, or crystallographic symmetries are mentioned. Microtubules are hollow cylinders of tubulin dimers (α/β), often arranged in 13 protofilaments — a 13-fold rotational symmetry (not a crystallographic point group in the strict sense, but a cyclic group C13). This is a lattice-like structure, but no mathematical analysis of its symmetry or any golden-ratio lin Author: Andrew Stewart Caldin, Independent Researcher, UK. Part of the E8 Intelligence Research series. Platform: e8intelligence.com
FINDING: Microtubule quantum coherence research suggests biological systems may sustain quantum effects (e.g., excitations, coherence) relevant to consciousness, but current evidence is largely computational/simulational, not experimentally conclusive. | MATH: No explicit equations in sources; key concepts: quantum coherence (superposition), decoherence rate (Γ), excitation propagation along tubulin lattice (periodicity ~8 nm dimer spacing, 13 protofilaments per microtubule → 13-fold symmetry). | CONNECTION: 13 protofilaments = prime number, related to Fibonacci (13 is F₇) and crystallographic-like helical symmetry (3-start, 8-start, 13-start lattice vectors — integer ratios 3:8:13, approximating golden ratio 8/13 ≈ 0.615, 13/8 ≈ 1.625, close to 0.618/1.618). | DEPTH: 4 — intriguing but speculative; no confirmed experimental quantum coherence in warm wet brain; mathematical structure of tubulin lattice (13-fold) is real but its link to consciousness is unproven. Author: Andrew Stewart Caldin, Independent Researcher, UK. Part of the E8 Intelligence Research series. Platform: e8intelligence.com
FINDING: Microtubule quantum coherence research suggests orchestrated quantum effects (Penrose-Hameroff Orch-OR) may operate in brain microtubules, with recent experimental evidence of quantum beats and coherent excitations in tubulin lattices. MATH: - Tubulin dimer spacing: ~8 nm (lattice constant), with helical pitch ~12 nm (3-start helix) → ratio 8/12 = 0.6667 (2/3) - Quantum beat frequency: ω = (E₂ - E₁)/ħ, where E₁, E₂ are ground-state superpositions (from arXiv:1401.3218) - Coherence time τ_c ~ 10⁻¹³–10⁻¹² s (thermal decoherence limit) vs. proposed Orch-OR window ~10⁻⁴ s → ratio ~10⁸–10⁹ - Microtubule lattice symmetry: hexagonal (6-fold) → crystallographic point group 6/mmm (D₆h) - Tubulin dimer dipole moment: ~1700 Debye (per dimer) → collective polarization P = N·p/V CONNECTION: - Hexagonal lattice → 60° angles → base-60 arithmetic (sexagesimal) naturally encodes 6-fold symmetry (360°/60° = 6) - Tubulin dimer spacing ratio 2/3 → approximates 0.6667, not golden Author: Andrew Stewart Caldin, Independent Researcher, UK. Part of the E8 Intelligence Research series. Platform: e8intelligence.com
FINDING: Quantum biology and consciousness research centers on microtubule quantum coherence, with Penrose–Hameroff Orch-OR theory as the dominant mathematical framework. | MATH: Key constants/structures: Planck time (5.39×10⁻⁴⁴ s), Planck mass (2.18×10⁻⁸ kg), quantum decoherence timescales (~10⁻¹³ s at 300K vs. proposed ~10⁻⁵ s in microtubules), tubulin dimer spacing (8 nm), microtubule lattice geometry (13 protofilaments, 3-start helix, 5-start helix — Fibonacci-related). Orch-OR invokes objective reduction (OR) with threshold E = ħ/t (energy-time uncertainty), where t is coherence time. | CONNECTION: Microtubule lattice is a hexagonal/crystallographic structure with 13-fold symmetry (protofilament count) — 13 is Fibonacci (F₇). The 3-start and 5-start helical pitch ratios (3:5) are consecutive Fibonacci numbers, yielding golden-ratio-adjacent pitch angles (~30° and ~50°). Tubulin dimers alternate α/β with 4 nm periodicity; the 8 nm dimer length × 13 protofilaments = 104 nm circumfer Author: Andrew Stewart Caldin, Independent Researcher, UK. Part of the E8 Intelligence Research series. Platform: e8intelligence.com
FINDING: Microtubule quantum coherence evidence suggests biological systems may exploit quantum superposition at mesoscale, but the mathematical core remains vibrational mode structure rather than proven consciousness-specific geometry. MATH: - Microtubule lattice: tubulin dimers arranged in 13-protofilament cylinders (13 = Fibonacci-adjacent prime), with 8nm dimer pitch and 4nm longitudinal spacing → helical symmetry group approximates a 3-start/13-start screw axis. - Quantum beat frequencies in cavity QED (arXiv:1401.3218): ω₁ - ω₂ = Δ (detuning), with second-order correlation g⁽²⁾(τ) = 1 + |g⁽¹⁾(τ)|² cos(Δτ) — coherence lifetime τ_c ∝ 1/γ (decoherence rate). - Excitation propagation in simulations: modeled as Fröhlich condensate at ~10¹¹ Hz (terahertz gap), with energy quanta ħω ≈ k_BT at 300K → ħω/k_BT ≈ 0.16 (not a golden ratio). - No published equation yet links quantum beats to 0.618 or 1.618. The 13-protofilament count is the only structural number with Fibonacci res Author: Andrew Stewart Caldin, Independent Researcher, UK. Part of the E8 Intelligence Research series. Platform: e8intelligence.com