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International Journal of Computer Information Systems and Industrial Management Applications

The Role of Quantum Machine Learning in the Transition from Industry 4.0 to Industry 5.0

Pijush Dutta, Mittapally Sandeep Reddy, Yogendra Chhetri, Rudrajit Datta, Anubrata Mondal, Tan Yi Fei, Chua Fang Fang

Published Jul 29, 2026• 0 citations
Publisher

Abstract

The current review's goal is to examine the strategic significance of Quantum Machine Learning (QML) as a technology tool or strategic enabler of Industry 5.0, the approaching industrial revolution. To summarize and categorize the most common forms, antecedents, and outcomes of sustainable innovation, the primary objective of this study is to systematically identify and critically evaluate the literature on sustainable innovation in Industry 5.0 since January 2020. A thorough search and review of 5984 scholarly articles were identified during the systematic review, and 36 publications were chosen by a cyclic filtration for a careful review in the fields of Industry 5.0 and QML to analyze the articles' contents. The findings demonstrate that QML provides a revolutionary improvement in decision-making platforms, system security, and data analytics in Industry 4.0. By taking into consideration a methodical and critical assessment of the research manuscripts, the proposed survey offers readers an impactful insight into the functions of quantum machine learning as an enabler to Industry 5.0 processes. QML is emphasized as a key driver for secure, intelligent, and sustainable industrial ecosystems through QML-assisted designs across various verticals, such as smart healthcare, manufacturing, digital twins, and Cobots, as this review methodically examines the enabling technologies shaping the Industry 5.0 vision. It also highlights how QML can improve decision-making, ensure post-quantum security, optimize resources, and speed up the realization of human-centric, energy-efficient, and resilient Industry 5.0 systems as quantum computing advances.

DOI
10.70917/ijcisim-2026-3955

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Quantum Computing (QC) and Artificial Intelligence (AI) have emerged as key technologies in the evolution of Industry 6.0, driving advancements in automation and advanced analytics, and process optimization. Their integration holds the potential to revolutionize sectors such as data science, healthcare, finance, and cybersecurity by enabling faster and more efficient computations through qubits, superposition, and quantum entanglement. However, the lack of structured knowledge regarding specific QC methodologies and applications in AI hinders its optimal implementation and development. Consequently, this study aims to identify the applications and variables associated with QC-AI integration. To this end, a systematic literature review was conducted following the PRISMA 2020 methodology, drawing on studies from Scopus and Web of Science databases. This enabled the analysis of trends, limitations, and opportunities in this technological convergence. This study aims to systematically examine the intersection of quantum computing and artificial intelligence by identifying the key technological features, integration requirements, and sectoral applications that define the current state of the field. The review contributes by mapping existing research, highlighting methodological approaches, and revealing gaps that may guide targeted advancements in hybrid quantum AI systems. The insights generated have the potential to accelerate innovation in high-impact domains such as healthcare, finance, energy, and cybersecurity. The findings indicate that the main advances in QC applied to AI focus on quantum optimization, Quantum Machine Learning (QML), and post-quantum cryptography. Notably, sectors such as energy, healthcare, and finance have shown significant progress in adopting these technologies. For example, in healthcare, QML has been applied to simulate molecular interactions to accelerate drug discovery, and in finance, it enhances predictive models for market behavior. The study concludes that although QC demonstrates substantial potential to enhance AI, its broader adoption remains constrained by reliance on NISQ hardware, the need for effective error correction, and the limited scalability of hybrid quantum classical algorithms. Addressing these challenges will be essential to establishing QML as a cornerstone of technological innovation and digital transformation. Additionally, this review introduces an integrative framework that categorizes key AI QC convergence dimensions and proposes a classification of application areas based on technical requirements and algorithmic capabilities. These contributions aim to guide future experimental validations and hybrid model development.
Quantum Machine Learning (QML), a confluence of quantum computing and classical machine learning, represents a revolutionary paradigm with transformative potential. This systematic review explores the landscape of QML by investigating its underlying principles, methodologies, diverse applications, challenges, and ethical considerations. Beginning with an examination of fundamental quantum computing principles, the review navigates through various QML methodologies, comparing them with classical counterparts. Real-world applications, ranging from quantum-enhanced optimization to drug discovery, are scrutinized, showcasing the practical implications of QML across industries. The paper systematically identifies challenges, including quantum hardware constraints and ethical considerations, while offering insights into current limitations and future research directions. A comparative analysis benchmarks QML against classical machine learning approaches, providing a nuanced understanding of its strengths and limitations. Ethical considerations underscore the importance of responsible AI practices in the integration of QML. The review concludes by identifying research gaps and suggesting future directions, emphasizing the need for continued exploration in this dynamic intersection of quantum computing and machine learning. This comprehensive exploration serves as a valuable resource for researchers, practitioners, and decision-makers seeking insights into the current state and transformative potential of Quantum Machine Learning.