Early and accurate identification of heart conditions from electrocardiogram (ECG) signals is particularly important for ongoing patient health monitoring, yet classical deep learning frameworks have been inadequate at achieving high accuracy and low latency under noisy, real-time conditions. This work focuses on developing a quantum-accelerated cardiac ECG (electrocardiogram) analysis. The study introduces a novel hybrid quantum–classical framework capable of simultaneously performing ECG denoising, feature embedding, and arrhythmia classification with reduced latency and improved robustness under noisy real-time conditions. The one introduced in the article is the hybrid quantum-classical architecture, including Quantum Variational ECG Embedding (QVEE) for high-dimensional morphological representation, Quantum Enhanced Denoising Module (QEDM) for noise suppression and signal distortion, and hybrid quantum classification for arrhythmia recognition. Experiments were conducted on the MIT-BIH Arrhythmia Database, and a corpus with noise augmentation showed that the proposed framework was found to be 99.4% correct with an F1 score of 0.97 and reduced the inference latency by 23.7% compared to state-of-the-art CNN-LSTM, Transformer-based models, and showed higher robustness under the condition of low signal-to-noise ratios. The results show that quantum embeddings tend to improve ECG feature separability and that quantum denoising helps preserve clinically relevant waveform structure (i.e., structure detection), particularly for rare arrhythmias. The proposed framework is a promising approach for establishing real-time quantum-assisted monitoring of the human heart, enabling more reliable early diagnosis in wearable and clinical environments.
Early and accurate identification of heart conditions from electrocardiogram (ECG) signals is particularly important for ongoing patient health monitoring, yet classical deep learning frameworks have been inadequate at achieving high accuracy and low latency under noisy, real-time conditions. This work focuses on developing a quantum-accelerated cardiac ECG (electrocardiogram) analysis. The study introduces a novel hybrid quantum–classical framework capable of simultaneously performing ECG denoising, feature embedding, and arrhythmia classification with reduced latency and improved robustness under noisy real-time conditions. The one introduced in the article is the hybrid quantum-classical architecture, including Quantum Variational ECG Embedding (QVEE) for high-dimensional morphological representation, Quantum Enhanced Denoising Module (QEDM) for noise suppression and signal distortion, and hybrid quantum classification for arrhythmia recognition. Experiments were conducted on the MIT-BIH Arrhythmia Database, and a corpus with noise augmentation showed that the proposed framework was found to be 99.4% correct with an F1 score of 0.97 and reduced the inference latency by 23.7% compared to state-of-the-art CNN-LSTM, Transformer-based models, and showed higher robustness under the condition of low signal-to-noise ratios. The results show that quantum embeddings tend to improve ECG feature separability and that quantum denoising helps preserve clinically relevant waveform structure (i.e., structure detection), particularly for rare arrhythmias. The proposed framework is a promising approach for establishing real-time quantum-assisted monitoring of the human heart, enabling more reliable early diagnosis in wearable and clinical environments.
Cardiovascular diseases (CVD) remain a leading cause of morbidity and mortality worldwide, with arrhythmia being one of their common manifestations. Traditional diagnostic methods, such as electrocardiography (ECG), rely heavily on expert interpretation for detecting irregular heart rhythms, which can lead to inaccuracies and delays in diagnosis, particularly in resource-limited settings. In recent years, machine learning (ML) has emerged as a powerful tool for improving the accuracy and efficiency of medical diagnostics. Although deep learning models have demonstrated remarkable success in various domains, their computational complexity poses challenges for real-time applications. This study investigates various quantum-classical hybrid algorithms for improving ECG-based arrhythmia classification. In this study, we employed three hybrid quantum-classical algorithms for arrhythmia detection, estimator-based Quantum Neural Network (QNN), sampler-based QNN, and Quantum Support Vector Classifier (QSVC), to enhance the accuracy of automated arrhythmia classification. The models are evaluated using the MIT-BIH arrhythmia database. The experimental results demonstrated that these three quantum models outperform traditional Recurrent Neural Networks (RNNs) and their variants in several metrics, including accuracy, sensitivity, and specificity. The QSVC (k = 16) model achieved the highest performance, with an accuracy of 97.7%, F1-score of 97.5%, and area under the receiver operating characteristic curve of 99.4%. Additionally, we developed an interactive application using StreamLit for real-time arrhythmia risk prediction and visual feedback. Overall, the proposed quantum ML model demonstrates significant potential for arrhythmia detection with robust and highly accurate performance, providing a solid foundation for future clinical deployment and integration into wearable devices.
Cardiac arrhythmia is a leading cause of sudden cardiac death, often occurring without warning and requiring early, accurate detection for effective intervention. However, their intermittent nature and reliance on expert ECG interpretation make timely diagnosis difficult, especially at scale. This study proposes a hybrid quantum-classical deep learning algorithm for automated arrhythmia detection using ECG images. The algorithm integrates a pre-trained ResNet50 for feature extraction with a 10-qubit variational quantum circuit, enhancing classification through quantum expressiveness. A dataset of 123,998 images, derived from MIT-BIH and PTB ECG recordings, was used to train the algorithm. Each image was resized to 224×224 pixels, and 10-dimensional ResNet50 features were processed by a quantum layer via PennyLane’s lightning.kokkos simulator. The algorithm achieved 99.98% test accuracy. Training was completed in an efficient manner, demonstrating both high performance and time-conscious execution, positioning quantum-enhanced algorithms as promising tools in real-time diagnostic cardiology.
Electrocardiography (ECG) is a primary diagnostic tool for identifying cardiac arrhythmias, a critical indicator of heart disease. While ECG signals contain vital information about the patient’s health conditions, their high-resolution waveform nature poses significant challenges in effective feature extraction. Recent advancements in quantum computing provide a transformative opportunity to accelerate research in data-driven predictive modeling for healthcare. This paper investigates a variety of Quantum Convolutional Neural Network (QCNN) architectures for ECG signal classification. By leveraging optimized convolutional structures, adaptable pooling layers, and advanced encoding techniques, our QCNN model is designed to preserve essential ECG characteristics while addressing challenges in dimensionality reduction. Experimental results demonstrate that our approach holds significant potential for enhanced arrhythmia classification. This innovative QCNN model has the potential to advance ECG-based diagnostics for heart disease, offering valuable support for clinical decision-making in cardiac care.
Early and accurate recognition of cardiovascular disease (CVD) using medical imaging is essential for timely clinical intervention and management. The objective of this study was to continue developing a hybrid quantum-classical deep learning system for the early detection and automatic triage of cardiovascular diseases using cardiac imaging information. The proposed method consists of a combination of efficient feature extraction via a lightweight classical convolutional neural network and a quantum-illness feature transformation and decision-refinement process implemented as a variational quantum circuit. A clinically informed triage module was added to rate patients into three risk categories (low-, moderate-, and high-risk). Experimental evaluation on a public cardiac magnetic resonance imaging (MRI) dataset revealed that the proposed framework achieved 94.5% classification accuracy and an area under the curve (AUC) of 0.96, with sensitivity exceeding that of state-of-the-art classical deep learning models. The results show that quantum-enhanced feature representations provide better class separability, robustness to Imaging noise, and improved learning efficiency. The results suggest that one way to overcome the limitations of conventional deep models is the hybrid quantum-classical learning approach, which is also compatible with near-term quantum hardware. This work raises the question of whether quantum-assisted artificial intelligence can enable scalable, real-time cardiovascular decision support systems and promote next-generation intelligent healthcare systems.
Early detection of clinical deterioration is crucial for better patient outcomes, and current diagnostic models struggle to model the complex interactions observed in nonlinear patterns in multimodal medical data while meeting the performance requirements for real-time operation. This paper proposes a Real-Time Hybrid Quantum-Classical Diagnostic Framework (HQCDF) to improve early disease detection by combining a Quantum Variational Biomarker Embedding module (QVBE), a Classical Temporal-Clinical Learning module (CTCLM), and a novel Quantum-Classical Diagnostic Fusion mechanism (QCDF). A semi-synthetic multimodal dataset, Med-EarlyQ, physiological time series, lab biomarkers, and clinical scores was built to evaluate. The hybrid model has been trained using End-to-end differentiable quantum-classical optimization via the parameter-shift rule. Results showed that HQCDF obtained 96% accuracy, 0.93 F1-score, and 0.95 AUROC to outperform state-of-the-art classical deep learning models and existing hybrid approaches by 6~15% while controlling the real-time inference latency to 18 ms. Analysis revealed that the QCDF module contributed to increased robustness against quantum noise and missing clinical information, and to QE's increased sensitivity to subtle trends in disease in its early stages. The results show that the proposed hybrid framework is a promising evolution, addressing the call for next-generation, real-time, and resource-efficient diagnostic systems with great potential for early intervention and clinical decision-support impact.
The electrocardiogram (ECG) is the most common technique used to diagnose heart diseases. The electrical signals produced by the heart are recorded by chest electrodes and by the extremity electrodes placed on the limbs. Many diseases, such as arrhythmia, cardiomyopathy, coronary heart disease, and heart failure, can be diagnosed by examining ECG signals. The interpretation of these signals by experts may take a long time, and there may be differences between expert interpretations. Since technological developments are intertwined with the medical sciences, computer-assisted diagnostic methods have recently come forward. In computer science, machine learning techniques are often preferred for automatic detection. Quantum-based structures have emerged to increase the machine learning algorithm's speed and classification performance. In this study, a quantum-based machine learning algorithm is applied to classify heart rhythms. The ECG properties were converted to qubit structure using principal component analysis (PCA). The resulting qubits are classified using the quantum support vector machine (QSVM) algorithm. Quantum computer simulation over Qiskit was used for classification studies. Within the scope of experimental studies, comparisons between classical SVM and QSVM were made using different data amounts and qubit numbers. In the results of the analysis, classical SVM achieved 86.96% accuracy, and QSVM achieved 84.64% accuracy. Despite the fact that the entire dataset was not used due to various limitations, these successful performances were achieved. Classification of medical data such as that from ECG has shown that quantum-based machine learning frameworks perform well despite current resource constraints. In this respect, the study includes essential contributions to the use of quantum-based machine learning methods on signal data in medicine.