Chiral-Quantum Biological Engine

This study establishes a rigorous quantitative boundary between engineered quantum systems and biological matter, defined by the thermodynamic cost of information protection. By benchmarking the 2025 Google “Willow” superconducting processor—which requires cryogenic isolation (20 mK) and active error correction to achieve a logical coherence time of 291 μs—against the biological requirement of 25 ms at 310 K, we identify a protection deficit of approximately $10^{12}$ . We demonstrate that standard gravitational collapse models (Orch OR) are falsified by radiative constraints ( $R_0$ limits) from underground experiments. Consequently, we propose and validate a hybrid architecture: nuclear spin memory (Posner molecules) stabilized by cytoskeletal chaperones, linked by chiral spintronic wires (microtubules), and read out via spin-gated ion channels. This model satisfies all physical constraints and is corroborated by recent experimental evidence of lithium isotope fractionation in calcium phosphate chemistry.This study establishes a rigorous quantitative boundary between engineered quantum systems and biological matter, defined by the thermodynamic cost of information protection. By benchmarking the 2025 Google “Willow” superconducting processor—which requires cryogenic isolation (20 mK) and active error correction to achieve a logical coherence time of 291 μs—against the biological requirement of 25 ms at 310 K, we identify a protection deficit of approximately $10^{12}$. We demonstrate that standard gravitational collapse models (Orch OR) are falsified by radiative constraints ($R_0$ limits) from underground experiments. Consequently, we propose and validate a hybrid architecture: nuclear spin memory (Posner molecules) stabilized by cytoskeletal chaperones, linked by chiral spintronic wires (microtubules), and read out via spin-gated ion channels. This model satisfies all physical constraints and is corroborated by recent experimental evidence of lithium isotope fractionation in calcium phosphate chemistry.

Dec 19, 20250 citations

Quantum Biology

Frontiers research topicsJan 1, 20260 citations

Coherent Quantum Engine

Juliette Monsel

Springer thesesJan 1, 20200 citations

Stimulated Chiral Light–Matter Interactions in Biological Microlasers

Zhiyi Yuan, Yunke Zhou, Zhen Qiao +4 more

Chiral light-matter interactions have emerged as a promising area in biophysics and quantum optics. Great progress in enhancing chiral light-matter interactions have been investigated through passive resonators or spontaneous emission. Nevertheless, the interaction between chiral biomolecules and stimulated emission remains unexplored. Here we introduce the concept of a biological chiral laser by amplifying chiral light-matter interactions in an active resonator through stimulated emission process. Green fluorescent proteins or chiral biomolecules encapsulated in Fabry-Perot microcavity served as the gain material while excited by either left-handed or right-handed circularly polarized pump laser. Owing to the nonlinear pump energy dependence of stimulated emission, significant enhancement of chiral light-matter interactions was demonstrated. Detailed experiments and theory revealed that a lasing dissymmetry factor is determined by molecular absorption dissymmetry factor at its excitation wavelength. Finally, chirality transfer was investigated under a stimulated emission process through resonance energy transfer. Our findings elucidate the mechanism of stimulated chiral light-matter interactions, providing better understanding of light-matter interaction in biophysics, chiral sensing, and quantum biophotonics.Chiral light-matter interactions have emerged as a promising area in biophysics and quantum optics. Great progress in enhancing chiral light-matter interactions have been investigated through passive resonators or spontaneous emission. Nevertheless, the interaction between chiral biomolecules and stimulated emission remains unexplored. Here we introduce the concept of a biological chiral laser by amplifying chiral light-matter interactions in an active resonator through stimulated emission process. Green fluorescent proteins or chiral biomolecules encapsulated in Fabry-Perot microcavity served as the gain material while excited by either left-handed or right-handed circularly polarized pump laser. Owing to the nonlinear pump energy dependence of stimulated emission, significant enhancement of chiral light-matter interactions was demonstrated. Detailed experiments and theory revealed that a lasing dissymmetry factor is determined by molecular absorption dissymmetry factor at its excitation wavelength. Finally, chirality transfer was investigated under a stimulated emission process through resonance energy transfer. Our findings elucidate the mechanism of stimulated chiral light-matter interactions, providing better understanding of light-matter interaction in biophysics, chiral sensing, and quantum biophotonics.

ACS NanoMay 14, 202153 citations

Quantum Biology

June Kinoshita

Scientific AmericanMay 1, 19890 citations

10^{12}

. We demonstrate that standard gravitational collapse models (Orch OR) are falsified by radiative constraints (

R_0

limits) from underground experiments. Consequently, we propose and validate a hybrid architecture: nuclear spin memory (Posner molecules) stabilized by cytoskeletal chaperones, linked by chiral spintronic wires (microtubules), and read out via spin-gated ion channels. This model satisfies all physical constraints and is corroborated by recent experimental evidence of lithium isotope fractionation in calcium phosphate chemistry.